Find Research Outputs

Search in all content

Filters for Research Output

Search concepts
Selected filters

Publication Year

  • 2019
  • 2018
  • 2017
  • 2016
  • 2015
  • 2014
  • 2013
  • 2012
  • 2011

Author

  • Richard Guy
2011

Imaging drug delivery to skin with stimulated Raman scattering microscopy

Saar, B. G., Contreras-Rojas, L. R., Xie, X. S. & Guy, R. H., 6 Jun 2011, In : Molecular Pharmaceutics. 8, 3, p. 969-975 7 p.

Research output: Contribution to journalArticle

Open Access
File
116 Citations (Scopus)
179 Downloads (Pure)
2015

Development and in vitro evaluation of lipid nanoparticle-based dressings for topical treatment of chronic wounds

Gainza, G., Chu, W. S., Guy, R. H., Pedraz, J. L., Hernandez, R. M., Delgado-Charro, B. & Igartua, M., 25 Jul 2015, In : International Journal of Pharmaceutics. 490, 1-2, p. 404-411 8 p.

Research output: Contribution to journalArticle

File
19 Citations (Scopus)
164 Downloads (Pure)
2016

Managing diabetes through the skin: Diagnostic devices

Guy, R., Jun 2016, In : Nature Nanotechnology. 11, 6, p. 493-494 2 p.

Research output: Contribution to journalArticle

Open Access
File
13 Citations (Scopus)
179 Downloads (Pure)
2015

Iontophoretic transdermal sampling of iohexol as a noninvasive tool to assess glomerular filtration rate

Djabri, A., van’t Hoff, W., Brock, P., Wong, I. C. K., Guy, R. & Delgado-Charro, B., 1 Feb 2015, In : Pharmaceutical Research. 32, 2, p. 590-603 14 p.

Research output: Contribution to journalArticle

Open Access
File
3 Citations (Scopus)
151 Downloads (Pure)
2014

Imaging drug delivery to skin with coherent raman scattering microscopy

Belsey, N. A., Contreras-Rojas, L. R. & Guy, R. H., 1 Jan 2014, Non Invasive Diagnostic Techniques in Clinical Dermatology. Springer Berlin Heidelberg, p. 225-231 7 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2018

Comparison of patient (POEM), observer (EASI, SASSAD, TIS) and corneometry measures of emollient effectiveness in children with eczema: findings from the COMET feasibility trial

Ridd, M. J., Gaunt, D. M., Guy, R. H., Redmond, N. M., Garfield, K., Hollinghurst, S., Ball, N., Shaw, L., Purdy, S. & Metcalfe, C., 1 Aug 2018, In : British Journal of Dermatology. 179, 2, p. 362-370 9 p.

Research output: Contribution to journalArticle

Open Access
File
2 Citations (Scopus)
45 Downloads (Pure)
2016

Ibuprofen delivery into and through the skin from novel oxidized cellulose-based gels and conventional topical formulations

Celebi, D., Edler, K., Scott, J. & Guy, R., 30 Nov 2016, In : International Journal of Pharmaceutics. 514, p. 238-243 6 p.

Research output: Contribution to journalArticle

Open Access
File
10 Citations (Scopus)
225 Downloads (Pure)
2015

Choice of Moisturiser for Eczema Treatment (COMET): Study protocol for a randomized controlled trial

Ridd, M. J., Redmond, N. M., Hollinghurst, S., Ball, N., Shaw, L., Guy, R., Wilson, V., Metcalfe, C. & Purdy, S., 15 Jul 2015, In : Trials. 16, 304.

Research output: Contribution to journalArticle

Open Access
File
14 Citations (Scopus)
102 Downloads (Pure)
2019

Stratum corneum sampling to assess bioequivalence between topical acyclovir products

Pensado-Lopez, A., Chiu, W. S., Cordery, S., Rantou, E., Bunge, A. L., Delgado-Charro, B. & Guy, R., 1 Dec 2019, In : Pharmaceutical Research. 36, 12, p. 180-196 16 p., 180.

Research output: Contribution to journalArticle

Open Access
2013
Open Access
File
9 Citations (Scopus)
156 Downloads (Pure)
2017

Bioequivalence methodologies for topical drug products: in vitro and ex vivo studies with a cortiscosteroid and an anti-fungal drug

Bastos Leal, L., Cordery, S. F., Delgado-Charro, M. B., Bunge, A. L. & Guy, R. H., Apr 2017, In : Pharmaceutical Research. 34, 4, p. 730-737 8 p.

Research output: Contribution to journalArticle

Open Access
10 Citations (Scopus)

Precise laser poration to control drug delivery into and through human nail

Vanstone, S., Cordery, S., Stone, J., Gordeev, S. & Guy, R., 28 Dec 2017, In : Journal of Controlled Release. 268, p. 72-77 6 p.

Research output: Contribution to journalArticle

Open Access
File
6 Citations (Scopus)
173 Downloads (Pure)
2019

Potential of iontophoresis as a drug delivery method for midazolam in pediatrics

Djabri, A., Guy, R. & Delgado-Charro, M., 1 Feb 2019, In : European Journal of Pharmaceutical Sciences. 128, p. 137-143 7 p.

Research output: Contribution to journalArticle

Open Access
File
2 Citations (Scopus)
35 Downloads (Pure)
2016

The potential of polymeric film-forming systems as sustained delivery platforms for topical drugs

Frederiksen, K., Guy, R. H. & Petersson, K., 2016, In : Expert Opinion on Drug Delivery. 13, 3, p. 349-360

Research output: Contribution to journalArticle

Open Access
File
19 Citations (Scopus)
191 Downloads (Pure)
2012

Transdermal iontophoresis of ranitidine: An opportunity in paediatric drug therapy

Djabri, A., Guy, R. H. & Delgado-Charro, M. B., 1 Oct 2012, In : International Journal of Pharmaceutics. 435, 1, p. 27-32

Research output: Contribution to journalArticle

Open Access
File
33 Citations (Scopus)
148 Downloads (Pure)
2011

Assessment of dermal exposure to pesticide residues during re-entry

Belsey, N. A., Cordery, S. F., Bunge, A. L. & Guy, R. H., 15 May 2011, In : Environmental Science & Technology. 45, 10, p. 4609-4615 7 p.

Research output: Contribution to journalArticle

Open Access
File
13 Citations (Scopus)
165 Downloads (Pure)
2013

Products in "Bounty bags" potentially harm newborn skin

Ridd, M., Guy, R., Ball, N., Roberts, A. & Williams, H., 22 Jun 2013, In : BMJ . 346, 7913, f3895.

Research output: Contribution to journalArticle

2015

In situ detection of salicylate in Ocimum basilicum plant leaves via reverse iontophoresis

González-Sánchez, M. I., Lee, P. T., Guy, R. H. & Compton, R. G., 28 Nov 2015, In : Chemical Communications. 51, 92, p. 16534-16536 3 p.

Research output: Contribution to journalArticle

Open Access
File
13 Citations (Scopus)
147 Downloads (Pure)
2012

Comparison of gravimetric and spectroscopic approaches to quantify stratum corneum removed by tape-stripping

Mohammed, D., Yang, Q., Guy, R. H., Matts, P. J., Hadgraft, J. & Lane, M. E., Sep 2012, In : European Journal of Pharmaceutics and Biopharmaceutics. 82, 1, p. 171-174

Research output: Contribution to journalArticle

33 Citations (Scopus)
2011

AFM nanotools for surgery of biological Cells

Beard, J. D., Gordeev, S. N. & Guy, R. H., 2011, In : Journal of Physics: Conference Series. 286, 1, 012003.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2019

Scanning the horizon: a systematic literature review of methodologies

Hines, P., Yu, L. H., Guy, R. & Papaluca-Amati, M., 27 May 2019, BMJ Open, 9, 5, p. e026764 9 p.

Research output: Contribution to specialist publicationArticle

Open Access
2 Citations (Scopus)
2015
Open Access
File
35 Citations (Scopus)
269 Downloads (Pure)
2019

The European Medicines Agency’s goals for regulatory science to 2025

Hines, P., Guy, R., Humphreys, A. & Papaluca-Amati, M., 3 Jun 2019, In : Nature Reviews Drug Discovery. 18, 6, p. 403-404 2 p.

Research output: Contribution to journalComment/debate

Open Access
File
6 Citations (Scopus)
25 Downloads (Pure)
2015
Open Access
File
10 Citations (Scopus)
160 Downloads (Pure)
2013

Mechanical tomography of human corneocytes with a nanoneedle

Beard, J. D., Guy, R. H. & Gordeev, S. N., Jun 2013, In : Journal Of Investigative Dermatology. 133, 6, p. 1565-1571 7 p.

Research output: Contribution to journalArticle

Open Access
File
18 Citations (Scopus)
127 Downloads (Pure)
2016

Femtosecond pulsed laser ablation to enhance drug delivery across the skin

Garvie-Cook, H., Stone, J. M., Yu, F., Guy, R. H. & Gordeev, S. N., 5 Jan 2016, In : Journal of Biophotonics. 9, 1-2, p. 144-154 11 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)
2013

Method for non-invasively determining the relative levels of two biological substances. T3

Delgado-Charro, M. & Guy, R., 4 Feb 2013, Patent No. ES2394691T, Priority date 22 Jun 2001, Priority No. EP01114750

Research output: Patent

2012
Open Access
File
17 Citations (Scopus)
152 Downloads (Pure)

Novel imaging method to quantify stratum corneum in dermatopharmacokinetic studies: Proof-of-concept with acyclovir formulations

Russell, L. M. & Guy, R. H., Dec 2012, In : Pharmaceutical Research. 29, 12, p. 3362-3372 11 p.

Research output: Contribution to journalArticle

Open Access
File
9 Citations (Scopus)
131 Downloads (Pure)
2015

Iontophoresis of minoxidil sulphate loaded microparticles, a strategy for follicular drug targeting?

Gelfuso, G. M., Barros, M. A. D. O., Delgado-Charro, M. B., Guy, R. H. & Lopez, R. F. V., Oct 2015, In : Colloids and Surfaces B: Biointerfaces. 134, p. 408-412 5 p.

Research output: Contribution to journalArticle

Open Access
File
20 Citations (Scopus)
170 Downloads (Pure)
2014

Characterisation of skin barrier function using bioengineering and biophysical techniques

Yang, Q. & Guy, R. H., 5 Aug 2014, In : Pharmaceutical Research. 32, 2, p. 445-457

Research output: Contribution to journalArticle

Open Access
File
7 Citations (Scopus)
180 Downloads (Pure)
2011
File
5 Citations (Scopus)
152 Downloads (Pure)
2012

Novel imaging method to quantify stratum corneum in dermatopharmacokinetic studies

Russell, L. M. & Guy, R. H., Sep 2012, In : Pharmaceutical Research. 29, 9, p. 2389-2397 9 p.

Research output: Contribution to journalArticle

Open Access
File
9 Citations (Scopus)
138 Downloads (Pure)

Method for non-invasively determining the relative levels of two biological substances. B1

Delgado-Charro, M. & Guy, R., 10 Oct 2012, IPC No. A61N1/30; (IPC1-7): A61N1/30, Patent No. EP1401532 (WO03000340), 17 Jun 2002, Priority date 22 Jun 2001, Priority No. 0114750.1 20010622 ; WO2002EP06637 20020617 ; EP20020747396 20020617

Research output: Patent

2016

Metals and the skin: Topical effects and systemic absorption

Guy, R. H., Hostýnek, J. J., Hinz, R. S. & Lorence, C. R., 19 Apr 2016, CRC Press. 431 p.

Research output: Book/ReportBook

4 Citations (Scopus)
2018

Non-invasive, transdermal, path-selective and specific glucose monitoring via a graphene-based platform

Lipani, L., Dupont, B. G. R., Doungmene, F., Marken, F., Tyrrell, R. M., Guy, R. H. & Ilie, A., 30 Jun 2018, In : Nature Nanotechnology. 13, 6, p. 504-511 8 p.

Research output: Contribution to journalArticle

Open Access
File
75 Citations (Scopus)
595 Downloads (Pure)

Topical bio(in)equivalence of metronidazole formulations in vivo

Pedon de Araujo, T., Moura Fittipaldi, I., Galindo Bedor, D. C., Ludna Duarte, M., Cordery, S., Guy, R., Delgado-Charro, M., Pereira de Santana, D. & Bastos Leal, L., 25 Apr 2018, In : International Journal of Pharmaceutics. 541, 1-2, p. 167-172 6 p.

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
42 Downloads (Pure)

Dermal Absorption of Pesticide Residues

Clarke, J., Cordery, S., Morgan, N. A., Knowles, P. & Guy, R., 17 Dec 2018, In : Chemical Research in Toxicology. 31, 12, p. 1356-1363

Research output: Contribution to journalArticle

File
2 Citations (Scopus)
43 Downloads (Pure)
2015

Biophysical elucidation of the mechanism of enhanced drug release and topical delivery from polymeric film-forming systems

Garvie-Cook, H., Frederiksen, K., Petersson, K., Guy, R. & Gordeev, S., 28 Aug 2015, In : Journal of Controlled Release. 212, p. 103-112 10 p.

Research output: Contribution to journalArticle

Open Access
File
10 Citations (Scopus)
162 Downloads (Pure)
2017

Topical bioavailability of diclofenac from locally-acting, dermatological formulations

Cordery, S. F., Pensado, A., Chiu, W. S., Shehab, M. Z., Bunge, A. L., Delgado-Charro, M. B. & Guy, R. H., 30 Aug 2017, In : International Journal of Pharmaceutics. 529, 1-2, p. 55-64 10 p.

Research output: Contribution to journalArticle

Open Access
File
16 Citations (Scopus)
220 Downloads (Pure)
2014

Transdermal drug delivery: 30 + years of war and still fighting!

Wiedersberg, S. & Guy, R. H., 28 Sep 2014, In : Journal of Controlled Release. 190, p. 150-156

Research output: Contribution to journalArticle

Open Access
File
121 Citations (Scopus)
287 Downloads (Pure)
2012

Objective assessment of nanoparticle disposition in mammalian skin after topical exposure

Campbell, C. S. J., Contreras-Rojas, L. R., Delgado-Charro, B. & Guy, R. H., 20 Aug 2012, In : Journal of Controlled Release. 162, 1, p. 201-207 7 p.

Research output: Contribution to journalArticle

Open Access
File
88 Citations (Scopus)
442 Downloads (Pure)
2019

Regulatory Science and Innovation Programme for Europe (ReScIPE): A proposed model

Hines, P. A., Guy, R. H., Brand, A., Humphreys, A. J. & Papaluca-Amati, M., 19 Aug 2019, In : British Journal Of Clinical Pharmacology. p. 1-6 6 p.

Research output: Contribution to journalArticle

Open Access
File
3 Citations (Scopus)
25 Downloads (Pure)
2015

Molecular diffusion in the human nail measured by stimulated Raman scattering microscopy

Chiu, W-S., Belsey, N., Garrett, N. L., Moger, J., Delgado-Charro, M. & Guy, R., 23 Jun 2015, In : Proceedings of the National Academy of Sciences of the United States of America. 112, 25, p. 7725-7730 6 p.

Research output: Contribution to journalArticle

Open Access
File
31 Citations (Scopus)
169 Downloads (Pure)

In vitro method to quantify dermal absorption of pesticide residues

Clarke, J. F., Cordery, S. F., Morgan, N. A., Knowles, P. K. & Guy, R. H., 16 Feb 2015, In : Chemical Research in Toxicology. 28, 2, p. 166-168

Research output: Contribution to journalArticle

Open Access
File
5 Citations (Scopus)
167 Downloads (Pure)
2013

Iontophoresis-targeted, follicular delivery of minoxidil sulfate for the treatment of alopecia

Gelfuso, G. M., Gratieri, T., Delgado-Charro, M. B., Guy, R. H. & Vianna Lopez, R. F., 1 May 2013, In : Journal of Pharmaceutical Sciences. 102, 5, p. 1488-1494

Research output: Contribution to journalArticle

25 Citations (Scopus)
2014
Open Access
File
31 Citations (Scopus)
209 Downloads (Pure)

Evaluation of drug delivery to intact and porated skin by coherent Raman scattering and fluorescence microscopies

Belsey, N. A., Garrett, N. L., Contreras-Rojas, L. R., Pickup-Gerlaugh, A. J., Price, G. J., Moger, J. & Guy, R. H., 28 Jan 2014, In : Journal of Controlled Release. 174, 28, p. 37-42 6 p.

Research output: Contribution to journalArticle

Open Access
File
43 Citations (Scopus)
230 Downloads (Pure)
2016

Modelling drug flux through microporated skin

Rzhevskiy, A. S., Guy, R. H. & Anissimov, Y. G., 10 Nov 2016, In : Journal of Controlled Release. 241, p. 194-199 6 p.

Research output: Contribution to journalArticle

Open Access
File
7 Citations (Scopus)
150 Downloads (Pure)

Choice of moisturiser for eczema treatment (COMET): feasibility study of a randomised controlled parallel group trial in children recruited from primary care

Ridd, M., Garfield, K., Gaunt, D., Hollinghurst, S., Redmond, N., Powell, K., Wilson, V., Guy, R., Ball, N., Shaw, L., Purdy, S. & Metcalfe, C., 16 Nov 2016, In : BMJ Open. 6, 11, 9 p., e012021.

Research output: Contribution to journalArticle

Open Access
12 Citations (Scopus)