2,5-Disubstituted furans from 1,4-alkynediols

S J Pridmore, P A Slatford, J M J Williams

Research output: Contribution to journalArticle

45 Citations (Scopus)


1-4-Alkynediols serve as readily available starting materials for isomerisation to 1,4-diketones, which can be converted in situ into the corresponding furans by acid-catalysed dehydration. A range of 2,5-disubstituted furans was prepared using the ruthenium-based catalyst Ru(PPh3)(3)(CO)H-2 with Xantphos at 1 mol % loading. (C) 2007 Published by Elsevier Ltd.
Original languageEnglish
Pages (from-to)5111-5114
Number of pages4
JournalTetrahedron Letters
Issue number29
Publication statusPublished - 2007


Cite this

Pridmore, S. J., Slatford, P. A., & Williams, J. M. J. (2007). 2,5-Disubstituted furans from 1,4-alkynediols. Tetrahedron Letters, 48(29), 5111-5114. https://doi.org/10.1016/j.tetlet.2007.05.069