2-substituted estradiol bis-sulfamates, multitargeted antitumor agents

synthesis, in vitro SAR, protein crystallography, and in vivo activity

Mathew P. Leese, Bertrand Leblond, Andrew Smith, Simon P. Newman, Anna Di Fiore, Giuseppina De Simone, Cladiu T. Supuran, Atul Purohit, Michael J. Reed, Barry V. L. Potter

Research output: Contribution to journalArticle

87 Citations (Scopus)
Original languageEnglish
Pages (from-to)7683-7696
JournalJournal of Medicinal Chemistry
Volume49
Issue number26
DOIs
Publication statusPublished - 2006

Keywords

  • in vitro

Cite this

2-substituted estradiol bis-sulfamates, multitargeted antitumor agents : synthesis, in vitro SAR, protein crystallography, and in vivo activity. / Leese, Mathew P.; Leblond, Bertrand; Smith, Andrew; Newman, Simon P.; Di Fiore, Anna; De Simone, Giuseppina; Supuran, Cladiu T.; Purohit, Atul; Reed, Michael J.; Potter, Barry V. L.

In: Journal of Medicinal Chemistry, Vol. 49, No. 26, 2006, p. 7683-7696.

Research output: Contribution to journalArticle

Leese, MP, Leblond, B, Smith, A, Newman, SP, Di Fiore, A, De Simone, G, Supuran, CT, Purohit, A, Reed, MJ & Potter, BVL 2006, '2-substituted estradiol bis-sulfamates, multitargeted antitumor agents: synthesis, in vitro SAR, protein crystallography, and in vivo activity', Journal of Medicinal Chemistry, vol. 49, no. 26, pp. 7683-7696. https://doi.org/10.1021/jm060705x
Leese, Mathew P. ; Leblond, Bertrand ; Smith, Andrew ; Newman, Simon P. ; Di Fiore, Anna ; De Simone, Giuseppina ; Supuran, Cladiu T. ; Purohit, Atul ; Reed, Michael J. ; Potter, Barry V. L. / 2-substituted estradiol bis-sulfamates, multitargeted antitumor agents : synthesis, in vitro SAR, protein crystallography, and in vivo activity. In: Journal of Medicinal Chemistry. 2006 ; Vol. 49, No. 26. pp. 7683-7696.
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