2-substituted estradiol bis-sulfamates, multitargeted antitumor agents: synthesis, in vitro SAR, protein crystallography, and in vivo activity

Mathew P. Leese, Bertrand Leblond, Andrew Smith, Simon P. Newman, Anna Di Fiore, Giuseppina De Simone, Cladiu T. Supuran, Atul Purohit, Michael J. Reed, Barry V. L. Potter

Research output: Contribution to journalArticle

90 Citations (Scopus)
Original languageEnglish
Pages (from-to)7683-7696
JournalJournal of Medicinal Chemistry
Volume49
Issue number26
DOIs
Publication statusPublished - 2006

Keywords

  • in vitro

Cite this

Leese, M. P., Leblond, B., Smith, A., Newman, S. P., Di Fiore, A., De Simone, G., Supuran, C. T., Purohit, A., Reed, M. J., & Potter, B. V. L. (2006). 2-substituted estradiol bis-sulfamates, multitargeted antitumor agents: synthesis, in vitro SAR, protein crystallography, and in vivo activity. Journal of Medicinal Chemistry, 49(26), 7683-7696. https://doi.org/10.1021/jm060705x