13C-Carbamylation as a mechanistic probe for the inhibition of class D β-lactamases by avibactam and halide ions

Christopher T. Lohans; David Y. Wang; Christian Jorgensen; Samuel T. Cahill; Ian J. Clifton; Michael A. McDonough; Henry P. Oswin; James Spencer; Carmen Domene Nunez; Timothy D.W. Claridge; Jürgen Brem; Christopher J. Schofield

doi:10.1039/c7ob01514c

13C-Carbamylation as a mechanistic probe for the inhibition of class D β-lactamases by avibactam and halide ions

Christopher T. Lohans
, David Y. Wang
, Christian Jorgensen
, Samuel T. Cahill
, Ian J. Clifton
, Michael A. McDonough
, Henry P. Oswin
, James Spencer
, Carmen Domene Nunez
, Timothy D.W. Claridge
, Jürgen Brem
, Christopher J. Schofield

Department of Chemistry

University of Oxford
King's College London
University of Bristol

Research output: Contribution to journal › Article › peer-review

20 Citations (SciVal)

Original language	English
Pages (from-to)	6024-6032
Number of pages	9
Journal	Organic and Biomolecular Chemistry
Volume	15
Issue number	28
DOIs	https://doi.org/10.1039/c7ob01514c
Publication status	Published - 28 Jul 2017

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10.1039/c7ob01514c

https://ora.ox.ac.uk/objects/uuid:6300cd93-8b87-4223-99f5-41b08a1e9296

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Lohans, C. T., Wang, D. Y., Jorgensen, C., Cahill, S. T., Clifton, I. J., McDonough, M. A., Oswin, H. P., Spencer, J., Domene Nunez, C., Claridge, T. D. W., Brem, J., & Schofield, C. J. (2017). 13C-Carbamylation as a mechanistic probe for the inhibition of class D β-lactamases by avibactam and halide ions. Organic and Biomolecular Chemistry, 15(28), 6024-6032. https://doi.org/10.1039/c7ob01514c

Lohans, CT, Wang, DY, Jorgensen, C, Cahill, ST, Clifton, IJ, McDonough, MA, Oswin, HP, Spencer, J, Domene Nunez, C, Claridge, TDW, Brem, J & Schofield, CJ 2017, '13C-Carbamylation as a mechanistic probe for the inhibition of class D β-lactamases by avibactam and halide ions', Organic and Biomolecular Chemistry, vol. 15, no. 28, pp. 6024-6032. https://doi.org/10.1039/c7ob01514c

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title = "13C-Carbamylation as a mechanistic probe for the inhibition of class D β-lactamases by avibactam and halide ions",

author = "Lohans, \{Christopher T.\} and Wang, \{David Y.\} and Christian Jorgensen and Cahill, \{Samuel T.\} and Clifton, \{Ian J.\} and McDonough, \{Michael A.\} and Oswin, \{Henry P.\} and James Spencer and \{Domene Nunez\}, Carmen and Claridge, \{Timothy D.W.\} and J{\"u}rgen Brem and Schofield, \{Christopher J.\}",

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AU - Lohans, Christopher T.

AU - Wang, David Y.

AU - Jorgensen, Christian

AU - Cahill, Samuel T.

AU - Clifton, Ian J.

AU - McDonough, Michael A.

AU - Oswin, Henry P.

AU - Spencer, James

AU - Domene Nunez, Carmen

AU - Claridge, Timothy D.W.

AU - Brem, Jürgen

AU - Schofield, Christopher J.

PY - 2017/7/28

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DO - 10.1039/c7ob01514c

M3 - Article

SN - 1477-0520

VL - 15

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EP - 6032

JO - Organic and Biomolecular Chemistry

JF - Organic and Biomolecular Chemistry

IS - 28

ER -

13C-Carbamylation as a mechanistic probe for the inhibition of class D β-lactamases by avibactam and halide ions

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