1,1-Diacyloxy-1-phenylmethanes as versatile N-acylating agents for amines

Robert S.L. Chapman, Joshua D. Tibbetts, Steven D. Bull

Research output: Contribution to journalArticle

  • 1 Citations

Abstract

1,1-Diacyloxy-1-phenylmethanes and 1-pivaloxy-1-acyloxy-1-phenylmethanes have been used as bench stable N-acylating reagents for primary and secondary amines and anilines under solvent-free conditions to afford their corresponding amides in good yield.

LanguageEnglish
Number of pages10
JournalTetrahedron
Early online date21 May 2018
DOIs
StatusE-pub ahead of print - 21 May 2018

Fingerprint

Aniline Compounds
Amides
Amines

Keywords

  • 1,1-Acylals
  • Amides
  • N-Acylation
  • Solvent free

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

Cite this

1,1-Diacyloxy-1-phenylmethanes as versatile N-acylating agents for amines. / Chapman, Robert S.L.; Tibbetts, Joshua D.; Bull, Steven D.

In: Tetrahedron, 21.05.2018.

Research output: Contribution to journalArticle

@article{73bd2f9efd8b4ab49b1ee75215550cdc,
title = "1,1-Diacyloxy-1-phenylmethanes as versatile N-acylating agents for amines",
abstract = "1,1-Diacyloxy-1-phenylmethanes and 1-pivaloxy-1-acyloxy-1-phenylmethanes have been used as bench stable N-acylating reagents for primary and secondary amines and anilines under solvent-free conditions to afford their corresponding amides in good yield.",
keywords = "1,1-Acylals, Amides, N-Acylation, Solvent free",
author = "Chapman, {Robert S.L.} and Tibbetts, {Joshua D.} and Bull, {Steven D.}",
year = "2018",
month = "5",
day = "21",
doi = "10.1016/j.tet.2018.05.044",
language = "English",
journal = "Tetrahedron",
issn = "0040-4020",
publisher = "PERGAMON-ELSEVIER SCIENCE LTD",

}

TY - JOUR

T1 - 1,1-Diacyloxy-1-phenylmethanes as versatile N-acylating agents for amines

AU - Chapman, Robert S.L.

AU - Tibbetts, Joshua D.

AU - Bull, Steven D.

PY - 2018/5/21

Y1 - 2018/5/21

N2 - 1,1-Diacyloxy-1-phenylmethanes and 1-pivaloxy-1-acyloxy-1-phenylmethanes have been used as bench stable N-acylating reagents for primary and secondary amines and anilines under solvent-free conditions to afford their corresponding amides in good yield.

AB - 1,1-Diacyloxy-1-phenylmethanes and 1-pivaloxy-1-acyloxy-1-phenylmethanes have been used as bench stable N-acylating reagents for primary and secondary amines and anilines under solvent-free conditions to afford their corresponding amides in good yield.

KW - 1,1-Acylals

KW - Amides

KW - N-Acylation

KW - Solvent free

UR - http://www.scopus.com/inward/record.url?scp=85048338873&partnerID=8YFLogxK

U2 - 10.1016/j.tet.2018.05.044

DO - 10.1016/j.tet.2018.05.044

M3 - Article

JO - Tetrahedron

T2 - Tetrahedron

JF - Tetrahedron

SN - 0040-4020

ER -