Abstract
1,1-Diacyloxy-1-phenylmethanes and 1-pivaloxy-1-acyloxy-1-phenylmethanes have been used as bench stable N-acylating reagents for primary and secondary amines and anilines under solvent-free conditions to afford their corresponding amides in good yield.
| Original language | English |
|---|---|
| Pages (from-to) | 5330-5339 |
| Number of pages | 10 |
| Journal | Tetrahedron |
| Volume | 74 |
| Issue number | 38 |
| Early online date | 21 May 2018 |
| DOIs | |
| Publication status | Published - 20 Sep 2018 |
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Keywords
- 1,1-Acylals
- Amides
- N-Acylation
- Solvent free
ASJC Scopus subject areas
- Biochemistry
- Drug Discovery
- Organic Chemistry
Cite this
Chapman, R. S. L., Tibbetts, J. D., & Bull, S. D. (2018). 1,1-Diacyloxy-1-phenylmethanes as versatile N-acylating agents for amines. Tetrahedron, 74(38), 5330-5339. https://doi.org/10.1016/j.tet.2018.05.044