Abstract
1,1-Diacyloxy-1-phenylmethanes and 1-pivaloxy-1-acyloxy-1-phenylmethanes have been used as bench stable N-acylating reagents for primary and secondary amines and anilines under solvent-free conditions to afford their corresponding amides in good yield.
| Original language | English |
|---|---|
| Pages (from-to) | 5330-5339 |
| Number of pages | 10 |
| Journal | Tetrahedron |
| Volume | 74 |
| Issue number | 38 |
| Early online date | 21 May 2018 |
| DOIs | |
| Publication status | Published - 20 Sep 2018 |
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Keywords
- 1,1-Acylals
- Amides
- N-Acylation
- Solvent free
ASJC Scopus subject areas
- Biochemistry
- Drug Discovery
- Organic Chemistry
Cite this
1,1-Diacyloxy-1-phenylmethanes as versatile N-acylating agents for amines. / Chapman, Robert S.L.; Tibbetts, Joshua D.; Bull, Steven D.
In: Tetrahedron, Vol. 74, No. 38, 20.09.2018, p. 5330-5339.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - 1,1-Diacyloxy-1-phenylmethanes as versatile N-acylating agents for amines
AU - Chapman, Robert S.L.
AU - Tibbetts, Joshua D.
AU - Bull, Steven D.
PY - 2018/9/20
Y1 - 2018/9/20
N2 - 1,1-Diacyloxy-1-phenylmethanes and 1-pivaloxy-1-acyloxy-1-phenylmethanes have been used as bench stable N-acylating reagents for primary and secondary amines and anilines under solvent-free conditions to afford their corresponding amides in good yield.
AB - 1,1-Diacyloxy-1-phenylmethanes and 1-pivaloxy-1-acyloxy-1-phenylmethanes have been used as bench stable N-acylating reagents for primary and secondary amines and anilines under solvent-free conditions to afford their corresponding amides in good yield.
KW - 1,1-Acylals
KW - Amides
KW - N-Acylation
KW - Solvent free
UR - http://www.scopus.com/inward/record.url?scp=85048338873&partnerID=8YFLogxK
U2 - 10.1016/j.tet.2018.05.044
DO - 10.1016/j.tet.2018.05.044
M3 - Article
AN - SCOPUS:85048338873
VL - 74
SP - 5330
EP - 5339
JO - Tetrahedron
JF - Tetrahedron
SN - 0040-4020
IS - 38
ER -