1,1-Diacyloxy-1-phenylmethanes as versatile N-acylating agents for amines

Robert S.L. Chapman, Joshua D. Tibbetts, Steven D. Bull

Research output: Contribution to journalArticle

2 Citations (Scopus)
10 Downloads (Pure)

Abstract

1,1-Diacyloxy-1-phenylmethanes and 1-pivaloxy-1-acyloxy-1-phenylmethanes have been used as bench stable N-acylating reagents for primary and secondary amines and anilines under solvent-free conditions to afford their corresponding amides in good yield.

Original languageEnglish
Pages (from-to)5330-5339
Number of pages10
JournalTetrahedron
Volume74
Issue number38
Early online date21 May 2018
DOIs
Publication statusPublished - 20 Sep 2018

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Aniline Compounds
Amides
Amines

Keywords

  • 1,1-Acylals
  • Amides
  • N-Acylation
  • Solvent free

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

Cite this

1,1-Diacyloxy-1-phenylmethanes as versatile N-acylating agents for amines. / Chapman, Robert S.L.; Tibbetts, Joshua D.; Bull, Steven D.

In: Tetrahedron, Vol. 74, No. 38, 20.09.2018, p. 5330-5339.

Research output: Contribution to journalArticle

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