Using single molecule spectroscopy to inform drug discovery in protein kinases

Project: Project at a former HEI

Imperial College Junior Research Fellowship

Ligand discrimination between active and inactive activation loop conformations of Aurora-A kinase is unmodified by phosphorylation
Gilburt, J., Girvan, P., Blagg, J., Ying, L. & Dodson, C., 14 Apr 2019, In: Chemical Science. 10, 14, p. 4069-4076 8 p.
Research output: Contribution to journal › Article › peer-review

Open Access
6 Citations (SciVal)

16 Downloads (Pure)
Dynamic Equilibrium of the Aurora A Kinase Activation Loop Revealed by Single-Molecule Spectroscopy
Gilburt, J., Sarkar, H., Sheldrake, P., Blagg, J., Ying, L. & Dodson, C., 6 Sept 2017, In: Angewandte Chemie International Edition. 56, 38, p. 11409-11414 6 p.
Research output: Contribution to journal › Article › peer-review

Open Access
28 Citations (SciVal)
Chemical amplification of magnetic field effects relevant to avian magnetoreception
Kattnig, D., Evans, E., Dejean, V., Dodson, C., Wallace, M., Mackenzie, S., Timmel, C. & Hore, P., 1 Feb 2016, In: Nature Chemistry. 8, p. 384-391 8 p.
Research output: Contribution to journal › Article › peer-review
74 Citations (SciVal)

Project Details