Using single molecule spectroscopy to inform drug discovery in protein kinases

Project: Project at a former HEI

Project Details

Description

Imperial College Junior Research Fellowship
Short title153567
StatusFinished
Effective start/end date1/12/1330/11/16

Research Output

  • 6 Article
  • 1 Conference contribution

Ligand discrimination between active and inactive activation loop conformations of Aurora-A kinase is unmodified by phosphorylation

Gilburt, J., Girvan, P., Blagg, J., Ying, L. & Dodson, C., 14 Apr 2019, In : Chemical Science. 10, 14, p. 4069-4076 8 p.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)
16 Downloads (Pure)

Dynamic equilibrium of Aurora-A kinase activation loop revealed by single molecule spectroscopy

Gilburt, J., Sarkar, H., Sheldrake, P., Blagg, J., Ying, L. & Dodson, C., 2017, EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS. Springer, Vol. 46. p. S315-S315 1 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Dynamic Equilibrium of the Aurora A Kinase Activation Loop Revealed by Single-Molecule Spectroscopy

Gilburt, J., Sarkar, H., Sheldrake, P., Blagg, J., Ying, L. & Dodson, C., 6 Sep 2017, In : Angewandte Chemie-International Edition. 56, 38, p. 11409-11414 6 p.

Research output: Contribution to journalArticle

Open Access
  • 13 Citations (Scopus)