The discovery and understanding of the reactivity of metal nanoparticles and their potential applications is slowly transforming our World due to their unique chemical and physical properties. However, their implementation is mainly limited by their tendency to agglomerate and sinter into bigger and more stable particles, losing their exceptional characteristics. The aim of this project is to stabilize metal nanoparticles using morphologically engineered supports overcoming the diffusion challenges faced by conventional stabilization approaches, specially relevant in catalytic applications. The potential of this new type of metal nanostructured catalyst will be explored in areas of green chemistry, environment and energy applications.