NANOSTRUCTURED HYDROGEL FILMS FOR ENCAPSULATION AND RELEASE

Project: Research council

Project Details

Description

We have recently discovered a new method of making solid nanostructured films of water soluble polymers with surfactants. These membranes form spontaneously at the surface of aqueous solutions of the two components, and contain highly ordered arrays of micelles surrounded and bound together by the polymer. The films are robust, can be easily lifted from the interface where they form, and will grow over an arbitrarily large area, the size of the container where they are prepared. Our preliminary experiments have shown that it is possible to incorporate hydrophobic material within the micelle array inside the films. The ability to encapsulate other molecules in these films raises the possibility of using them for sustained release applications to deliver eg drugs, flavours, pesticides etc. In this proposal we will work to develop polymer-surfactant membrane-forming systems to optimise nanostructure formation and encapsulation properties and to map the relationship between polymer and surfactant properties and those of the resulting membrane. This new method provides a simple, cheap and straightforward method to creating large areas of free-standing polymer membranes with encapsulated material and in this proposal we will particularly target formation of the membranes from biocompatible polymers towards potential drug release applications.
StatusFinished
Effective start/end date11/07/0710/01/11

Funding

  • Engineering and Physical Sciences Research Council

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  • Research Output

    Controlling interfacial film formation in mixed polymer-surfactant systems by changing the vapor phase

    Mokhtari, T., Pham, Q. D., Hirst, C., O'Driscoll, B. M. D., Nylander, T., Edler, K. J. & Sparr, E., 26 Aug 2014, In : Langmuir. 30, 33, p. 9991-10001 11 p.

    Research output: Contribution to journalArticle

  • 5 Citations (Scopus)

    Water-responsive internally structured polymer-surfactant films on solid surfaces

    Gustavsson, C., Li, J., Edler, K. J. & Piculell, L., 28 Oct 2014, In : Langmuir. 30, 42, p. 12525-12531 7 p.

    Research output: Contribution to journalArticle

  • 7 Citations (Scopus)

    Formation of mesostructured thin films at the air–liquid interface

    Edler, K. J. & Yang, B., 7 May 2013, In : Chemical Society Reviews. 42, 9, p. 3765-3776 12 p.

    Research output: Contribution to journalArticle

  • 28 Citations (Scopus)