Factory in a Fumehood: Reagentless Flow Reactors as Enabling Techniques for Manufacture

  • Lewis, Dave (PI)

Project: Research council

Project Details


This proposal aims to bring together a unique team of scientists from academia and industry to develop new enabling manufacturing techniques for the reagentless synthesis of high value chemical products. Why reagentless? In traditional chemical processes once a reagent has performed its task it needs to be removed from the product stream. Unless the spent reagent can be reactivated then the waste stream must be dealt with. Most processes require large amounts of reagent, placing a heavy financial and environmental burden on manufacturing of high value products such as pharmaceuticals. The Holy Grail would be to avoid reagents altogether. Photochemisty, electrochemistry and thermochemistry are reagentless techniques, requiring only electrical energy as a primary input and will be the focus of this project in order to provide new enabling techniques for manufacturing. By the use of flow chemistry techniques these three areas can be connected together to provide rapid access to complex, high value products - this is conceptualized as a 'Factory in a Fumehood' - where scale-up can be achieved with a small footprint and with greatly reduced operating costs and waste.
Effective start/end date1/07/1330/06/16

Collaborative partners

  • University of Bath (lead)
  • University of Bristol
  • University of Reading
  • University of Southampton
  • AstraZeneca UK Ltd
  • GlaxoSmithKline


  • Engineering and Physical Sciences Research Council


Explore the research topics touched on by this project. These labels are generated based on the underlying awards/grants. Together they form a unique fingerprint.