COOPERATIVE GROUP IN ORGANOGENESIS, GROWTH AND REGENERATION

Research output

Research output per year 2005 2005 2006 2007 2008 2009 2010 2017

• 104 Article
• 5 Chapter or section
• 3 Review article
• 1 Meeting abstract
• 1 More
  • 1 Letter

Research output per year

Research output per year

Search results

• 2017

  Highly potent and isoform-selective dual-site-binding tankyrase/Wnt signaling inhibitors that increase cellular glucose uptake and have anti-proliferative activity

  Nathubhai, A., Haikarainen, T., Koivunen, J., Murthy, S., Koumanov, F., Lloyd, M., Holman, G., Pihlajaniemi, T., Tosh, D., Lehtio, L. & Threadgill, M., 26 Jan 2017, In: Journal of Medicinal Chemistry. 60, 2, p. 814-820 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Wnt Signaling 100%
  • IC50 100%
  • Antiproliferative Activity 100%
  • Binding Site 100%
  • Glucose Uptake 100%
  50 Citations (SciVal)

  368 Downloads (Pure)

• Rab28 is a TBC1D1/TBC1D4 substrate involved in GLUT4 trafficking

  Zhou, Z., Menzel, F., Benninghoff, T., Chadt, A., Du, C., Holman, G. D. & Al-Hasani, H., 1 Jan 2017, In: FEBS Letters. 591, 1, p. 88-96 9 p.

  Research output: Contribution to journal › Letter › peer-review

  • Skeletal Muscle 100%
  • Adipose Tissue 100%
  • TBC1D4 100%
  • GLUT4 100%
  • Muscle Cell 50%
  18 Citations (SciVal)
• 2016

  The causal role of breakfast in energy balance and health: A randomized controlled trial in obese adults

  Chowdhury, E., Richardson, J., Holman, G. D., Tsintzas, K., Thompson, D. & Betts, J., 1 Mar 2016, In: The American Journal of Clinical Nutrition. 103, 3, p. 747-756 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Physical Activity 100%
  • Energy Intake 75%
  • Thermogenesis 75%
  • Adipose Tissue 25%
  • Dual-Energy X-Ray Absorptiometry 25%
  141 Citations (SciVal)

  62 Downloads (Pure)
• 2015

  Deletion of Both Rab-GTPase–Activating Proteins TBC1D1 and TBC1D4 in Mice Eliminates Insulin- and AICAR-Stimulated Glucose Transport

  Chadt, A., Immisch, A., De Wendt, C., Springer, C., Zhou, Z., Stermann, T., Holman, G. D., Loffing-cueni, D., Loffing, J., Joost, H.-G. & Al-hasani, H., Mar 2015, In: Diabetes. 64, 3, p. 746-759 14 p.

  Research output: Contribution to journal › Article › peer-review

  • TBC1D4 100%
  • GLUT4 100%
  • Glucose Transport 100%
  • Skeletal Muscle 75%
  • Adipose Tissue 50%
  72 Citations (SciVal)

• Insulin regulates Rab3–Noc2 complex dissociation to promote GLUT4 translocation in rat adipocytes

  Koumanov, F., Pereira, V. J., Richardson, J. D., Sargent, S. L., Fazakerley, D. J. & Holman, G. D., 1 Aug 2015, In: Diabetologia. 58, 8, p. 1877-1886 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • GLUT4 100%
  • Adipocyte 100%
  • Cell Membrane 75%
  • Guanosine Triphosphate 57%
  • Skeletal Muscle 25%
  14 Citations (SciVal)

  51 Downloads (Pure)

• Physiological and molecular responses to an acute bout of reduced-exertion high-intensity interval training (REHIT)

  Metcalfe, R. S., Koumanov, F., Ruffino, J. S., Stokes, K. A., Holman, G. D., Thompson, D. & Vollaard, N. B. J., Nov 2015, In: European Journal of Applied Physiology. 115, 11, p. 2321-2334 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Exercise 100%
  • High Intensity Interval Training 100%
  • Blood Plasma 100%
  • Cell Signaling 33%
  • Gene Expression 33%
  79 Citations (SciVal)

  396 Downloads (Pure)

• Proteomic Analysis of GLUT4 Storage Vesicles Reveals Tumour Suppressor Candidate 5 (TUSC5) as a Novel Regulator of Insulin Action in Adipocytes

  Fazakerley, D. J., Naghiloo, S., Chaudhuri, R., Koumanov, F., Burchfield, J. G., Thomas, K. C., Krycer, J. R., Prior, M. J., Parker, B. L., Murrow, B. A., Stöckli, J., Meoli, C. C., Holman, G. D. & James, D. E., 25 Sept 2015, In: The Journal of biological chemistry. 290, 39, p. 23528-23542 15 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Proteomics 100%
  • Tumor Suppressor Protein 100%
  • Adipocyte 100%
  • Glucose Transporter 100%
  • GLUT4 55%
  48 Citations (SciVal)
• 2014

  Developmental Programming Mediated by Complementary Roles of Imprinted Grb10 in Mother and Pup

  Cowley, M., Garfield, A. S., Madon-Simon, M., Charalambous, M., Clarkson, R. W., Smalley, M. J., Kendrick, H., Isles, A. R., Parry, A. J., Carney, S., Oakey, R. J., Heisler, L. K., Moorwood, K., Wolf, J. B. & Ward, A., 28 Feb 2014, In: PLoS Biology. 12, 2, p. 1-13 13 p., e1001799.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Progeny 100%
  • Genetics 50%
  • Health Status 33%
  • Homeostasis 16%
  • Mediator 16%
  44 Citations (SciVal)

  50 Downloads (Pure)

• The causal role of breakfast in energy balance and health: A randomized controlled trial in lean adults

  Betts, J., Richardson, J. D., Chowdhury, E., Holman, G. D., Tsintzas, K. & Thompson, D., 1 Aug 2014, In: The American Journal of Clinical Nutrition. 100, 2, p. 539-547 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Randomized Controlled Trial 100%
  • Energy Balance 100%
  • Energy Intake 100%
  • Glucose Blood Level 66%
  • Metabolic Pathway 33%
  181 Citations (SciVal)

  58 Downloads (Pure)
• 2012

  A novel transgenic line using the Cre-lox system to allow permanent lineage-labeling of the zebrafish neural crest

  Rodrigues, F. S. L. M., Doughton, G., Yang, B. & Kelsh, R. N., 2012, In: Genesis. 50, 10, p. 750-757

  Research output: Contribution to journal › Article › peer-review

  • Neural Crest 100%
  • Stem Cell 33%
  • Promoter Region 33%
  • Oligodendrocyte 33%
  • Cytotechnology 16%
  31 Citations (SciVal)

• GLUT4 Traffic through an ESCRT-III-Dependent Sorting Compartment in Adipocytes

  Koumanov, F., Pereira, V. J., Whitley, P. R. & Holman, G. D., 25 Sept 2012, In: PLoS ONE. 7, 9, e44141.

  Research output: Contribution to journal › Article › peer-review

  • GLUT4 100%
  • Adipocyte 100%
  • Endosomal Sorting Complex Required Transport 100%
  • Glucose Transporter 4 100%
  • Cell Surface 50%
  19 Citations (SciVal)
• 2011

  An iterative genetic and dynamical modelling approach identifies novel features of the gene regulatory network underlying melanocyte development

  Greenhill, E. R., Rocco, A., Vibert, L., Nikaido, M. & Kelsh, R. N., 1 Sept 2011, In: Plos Genetics. 7, 9, 18 p., e1002265.

  Research output: Contribution to journal › Article › peer-review

  • Genetics 100%
  • Melanocyte 100%
  • Gene Regulatory Network 100%
  • Zebra Fish 16%
  • Neural Crest 16%
  59 Citations (SciVal)

• Deciphering the cellular and molecular roles of cellular nucleic acid binding protein during cranial neural crest development

  Weiner, A. M. J., Sdrigotti, M. A., Kelsh, R. N. & Calcaterra, N. B., 2011, In: Development Growth & Differentiation. 53, 8, p. 934-947

  Research output: Contribution to journal › Article › peer-review

  • Binding Protein 100%
  • Cranial Neural Crest 100%
  • Nucleic Acid Binding 100%
  • Morpholino 42%
  • Neural Crest 28%
  21 Citations (SciVal)

• Distinct physiological and behavioural functions for parental alleles of imprinted Grb10

  Garfield, A. S., Cowley, M., Smith, F. M., Moorwood, K., Stewart-Cox, J. E., Gilroy, K., Baker, S., Xia, J., Dalley, J. W., Hurst, L. D., Wilkinson, L. S., Isles, A. R. & Ward, A., 27 Jan 2011, In: Nature. 469, 7331, p. 534-538 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Social Behavior 100%
  • Allele 100%
  • Behavior (Neuroscience) 66%
  • Receptor Tyrosine Kinase 33%
  • Adaptor Protein 33%
  169 Citations (SciVal)
• 2010

  Barrett's metaplasia: molecular mechanisms and nutritional influences

  Slack, J. M. W., Colleypriest, B. J., Quinlan, J. M., Yu, W. Y., Farrant, J. M. & Tosh, D., Apr 2010, In: Biochemical Society Transactions. 38, 2, p. 313-319 7 p.

  Research output: Contribution to journal › Article

  • Metaplasia 100%
  • Homeobox 100%
  • Tissue (Anatomy) 57%
  • Transcription Factors 33%
  • Gene Expression 33%
  8 Citations (SciVal)

• GroEL dependency affects codon usage-support for a critical role of misfolding in gene evolution

  Warnecke, T. & Hurst, L. D., 19 Jan 2010, In: Molecular Systems Biology. 6, 340.

  Research output: Contribution to journal › Article › peer-review

  File

  • Codon 100%
  • Codon Usage 100%
  • Gene Evolution 100%
  • GroEL 100%
  • Escherichia coli 40%
  52 Citations (SciVal)

  194 Downloads (Pure)

• Human RASSF7 regulates the microtubule cytoskeleton and is required for spindle formation, Aurora B activation and chromosomal congression during mitosis

  Recino, A., Sherwood, V., Flaxman, A., Cooper, W., Latif, F., Ward, A. & Chalmers, A. D., 30 Sept 2010, In: Biochemical Journal. 430, 2, p. 207-213 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Minoxidil 100%
  27 Citations (SciVal)

  73 Downloads (Pure)

• In vitro reprogramming of pancreatic cells to hepatocytes

  Eberhard, D., O’Neill, K., Burke, Z. D. & Tosh, D., 2010, Cellular Programming and Reprogramming: Methods and Protocols. Ding, S. (ed.). 636 ed. Humana Press, p. 285-292 8 p. (Methods in Molecular Biology).

  Research output: Chapter or section in a book/report/conference proceeding › Chapter or section

  • In Vitro 100%
  • Hepatocyte 100%
  • Cell Transdifferentiation 80%
  • Glucocorticoid 40%
  • Cell Line 20%
  5 Citations (SciVal)

• Isolation, culture, and characterisation of mouse embryonic oesophagus and intestine

  Quinian, J. M., Yu, W.-Y. & Tosh, D., 2010, Mouse Cell Culture: Methods and Protocols. Ward, A. & Tosh, D. (eds.). 633 ed. Humana Press, p. 81-90 10 p. (Methods in Molecular Biology).

  Research output: Chapter or section in a book/report/conference proceeding › Chapter or section

  • Mouse 100%
  • Esophagus 100%
  • Intestine 100%
  • Gastrointestinal Tract 50%
  • Fibronectin 25%
  1 Citation (SciVal)

• Isolation and culture of adult mouse hepatocytes

  Li, W.-C., Ralphs, K. L. & Tosh, D., 2010, Mouse Cell Culture: Methods and Protocols. Ward, A. & Tosh, D. (eds.). 633 ed. Humana Press, p. 185-196 12 p. (Methods in Molecular Biology).

  Research output: Chapter or section in a book/report/conference proceeding › Chapter or section

  • Hepatocyte 100%
  • Collagenase 50%
  • Perfusion 50%
  • In Vitro 25%
  • Transgenic Mouse 25%
  233 Citations (SciVal)

• Isolation and culture of embryonic pancreas and liver

  Burke, Z. D., Li, W.-C., Slack, J. & Tosh, D., 2010, Mouse Cell Culture: Methods and Protocols. Ward, A. & Tosh, D. (eds.). 633 ed. Humana Press, p. 91-99 9 p. (Methods in Molecular Biology).

  Research output: Chapter or section in a book/report/conference proceeding › Chapter or section

  • Pancreas 100%
  • Immunostaining 100%
  • Organogenesis 100%
  • Fibronectin 100%
  5 Citations (SciVal)

• Kinetic evidence for unique regulation of GLUT4 trafficking by insulin and AMP-activated protein kinase activators in L6 myotubes

  Fazakerley, D. J., Holman, G. D., Marley, A., James, D. E., Stockli, J. & Coster, A. C. F., 15 Jan 2010, In: Journal of Biological Chemistry. 285, 3, p. 1653-1660 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Hydroxymethylglutaryl Coenzyme A Reductase Kinase Activator 100%
  • Glucose Transporter 4 100%
  • Myotube 100%
  • Immunology 100%
  • AMP-activated Protein Kinase 100%
  67 Citations (SciVal)

• Maternally-inherited Grb10 reduces placental size and efficiency

  Charalambous, M., Cowley, M., Geoghegan, F., Smith, F. M., Radford, E. J., Marlow, B. P., Graham, C. F., Hurst, L. D. & Ward, A., 1 Jan 2010, In: Developmental Biology. 337, 1, p. 1-8 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Allele 100%
  • Fetus Growth 100%
  • Placenta 50%
  • Placenta Development 50%
  • Progeny 50%
  81 Citations (SciVal)

• Streptozotocin-induced diabetes modulates action potentials and ion channel currents from the rat atrioventricular node

  Yuill, K. H., Tosh, D. & Hancox, J. C., Apr 2010, In: Experimental Physiology. 95, 4, p. 508-517 10 p.

  Research output: Contribution to journal › Article › peer-review
  11 Citations (SciVal)

• The N-terminal RASSF family: a new group of Ras-association-domain-containing proteins, with emerging links to cancer formation

  Sherwood, V., Recino, A., Jeffries, A., Ward, A. & Chalmers, A. D., 2010, In: Biochemical Journal. 425, 2, p. 303-311 9 p.

  Research output: Contribution to journal › Review article › peer-review

  File

  • N-Terminus 100%
  • Protein Family 100%
  • Amino Terminal Sequence 100%
  • Tumor Suppressor Protein 28%
  • Cell Death 14%
  83 Citations (SciVal)

  299 Downloads (Pure)

• The role of Cdx2 in Barrett's metaplasia

  Colleypriest, B. J., Farrant, J. M., Slack, J. M. W. & Tosh, D., Apr 2010, In: Biochemical Society Transactions. 38, 2, p. 364-369 6 p.

  Research output: Contribution to journal › Article

  • Homeobox 100%
  • Metaplasia 100%
  • Intestine 40%
  • Regulator Gene 20%
  • Transcription Factors 20%
  19 Citations (SciVal)

• The role of scaffold proteins in JNK signalling

  Engstrom, W., Ward, A. & Moorwood, K., Feb 2010, In: Cell Proliferation. 43, 1, p. 56-66 11 p.

  Research output: Contribution to journal › Review article › peer-review

  • Scaffold Protein 100%
  • Signal Transduction 66%
  • Intracellular Signaling 33%
  • Cell Cycle 33%
  52 Citations (SciVal)

• Timing of replication is a determinant of neutral substitution rates but does not explain slow Y chromosome evolution in rodents

  Pink, C. J. & Hurst, L. D., May 2010, In: Molecular Biology and Evolution. 27, 5, p. 1077-1086 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Autosome 100%
  • Y Chromosome 100%
  • S Phase 22%
  • Y Chromosomal Inheritance 22%
  • Mutation Rate 11%
  24 Citations (SciVal)

• Unique cost dynamics elucidate the role of frameshifting errors in promoting translational robustness

  Warnecke, T., Huang, Y., Przytycka, T. M. & Hurst, L. D., 5 Aug 2010, In: Genome biology and evolution. 2, p. 636-645 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Ribosome 100%
  • Dynamics 100%
  • Microbial Genome 100%
  • Codon Usage 100%
  • Anticodon 100%
  9 Citations (SciVal)
• 2009

  A common trafficking route for GLUT4 in cardiomyocytes in response to insulin, contraction and energy-status signalling

  Fazakerley, D. J., Lawrence, S. P., Lizunov, V. A., Cushman, S. W. & Holman, G. D., 1 Mar 2009, In: Journal of Cell Science. 122, 5, p. 727-734 8 p.

  Research output: Contribution to journal › Article › peer-review

  • GLUT4 100%
  • Cardiac Muscle Cell 100%
  • Sarcolemma 50%
  • Internalization 28%
  • T-Tubule 28%
  43 Citations (SciVal)

• A zebrafish model for Waardenburg syndrome type IV reveals diverse roles for Sox10 in the otic vesicle

  Dutton, K., Abbas, L., Spencer, J., Brannon, C., Mowbray, C., Nikaido, M., Kelsh, R. N. & Whitfield, T. T., Jan 2009, In: Disease Models and Mechanisms. 2, 1-2, p. 68-83 16 p.

  Research output: Contribution to journal › Article › peer-review

  • Otic Vesicle 100%
  • SOX10 100%
  • Neural Crest 50%
  • Melanocyte 16%
  • Gene Expression 16%
  47 Citations (SciVal)

• Cdx genes, inflammation and the pathogenesis of Barrett's metaplasia

  Colleypriest, B. J., Palmer, R. M., Ward, S. G. & Tosh, D., Jul 2009, In: Trends in Molecular Medicine. 15, 7, p. 313-322 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Metaplasia 100%
  • Esophageal Adenocarcinoma 22%
  • Tissue (Anatomy) 11%
  • Neoplasm 11%
  • Malignant Neoplasm 11%
  27 Citations (SciVal)

• Does negative auto-regulation increase gene duplicability?

  Warnecke, T., Wang, G. Z., Lercher, M. J. & Hurst, L. D., Aug 2009, In: BMC Evolutionary Biology. 9, 193.

  Research output: Contribution to journal › Article › peer-review

  File
  3 Citations (SciVal)

  150 Downloads (Pure)

• Dual ablation of Grb10 and Grb14 in mice reveals their combined role in regulation of insulin signaling and glucose homeostasis

  Holt, L. J., Lyons, R. J., Ryan, A. S., Beale, S. M., Ward, A., Cooney, G. J. & Daly, R. J., 2009, In: Molecular Endocrinology. 23, 9, p. 1406-1414 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Insulin Signaling 100%
  • Glucose Homeostasis 100%
  • Insulin Receptor 75%
  • Body Composition 50%
  • Knockout Mouse 25%
  49 Citations (SciVal)

• Evidence that replication-associated mutation alone does not explain between-chromosome differences in substitution rates

  Pink, C. J., Swaminathan, S. K., Dunham, I., Rogers, J., Ward, A. & Hurst, L. D., May 2009, In: Genome biology and evolution. 2009, p. 13-22 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Autosome 100%
  • Intron 50%
  • Germ Line 50%
  • Evolutionary Rate 50%
  • Bacterial Artificial Chromosome 50%

• Evolutionary genomics and the reach of selection

  Hurst, L. D., Feb 2009, In: Journal of Biology. 8, 2, p. 12 1 p.

  Research output: Contribution to journal › Article › peer-review
  16 Citations (SciVal)

• Frequent long-range epigenetic silencing of Protocadherin gene clusters on chromosome 5q31 in Wilms' Tumor

  Dallosso, A. R., Hancock, A. L., Szemes, M., Moorwood, K., Chilukamarri, L., Tsai, H. H., Sarkar, A., Barasch, J., Vuononvirta, R., Jones, C., Pritchard-Jones, K., Royer-Pokora, B., Lee, S. B., Owen, C., Malik, S., Feng, Y., Frank, M., Ward, A., Brown, K. W. & Malik, K., 26 Nov 2009, In: Plos Genetics. 5, 11, 13 p., e1000745.

  Research output: Contribution to journal › Article › peer-review

  File

  • Polymerase Chain Reaction 100%
  126 Citations (SciVal)

  196 Downloads (Pure)

• Fundamental concepts in genetics: Genetics and the understanding of selection

  Hurst, L. D., 2009, In: Nature Reviews Genetics. 10, 2, p. 83-93 11 p.

  Research output: Contribution to journal › Article › peer-review
  100 Citations (SciVal)

• How does inflammation cause Barrett's metaplasia?

  Colleypriest, B. J., Ward, S. G. & Tosh, D., Dec 2009, In: Current Opinion in Pharmacology. 9, 6, p. 721-726 6 p.

  Research output: Contribution to journal › Article › peer-review
  43 Citations (SciVal)

• Inhibition of Hes1 activity in gall bladder epithelial cells promotes insulin expression and glucose responsiveness

  Coad, R. A., Dutton, J. R., Tosh, D. & Slack, J., 2009, In: Biochemistry and Cell Biology - Biochimie Et Biologie Cellulaire. 87, 6, p. 975-987 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Epithelial Cell 100%
  • Gallbladder 100%
  • Gall Bladder 100%
  • Epithelial Cells 100%
  • Transcription Factors 100%
  14 Citations (SciVal)

• Liver zonation occurs through a β-catenin–dependent, c-Myc–independent mechanism

  Burke, Z. D., Reed, K. R., Phesse, T. J., Sansom, O. J., Clarke, A. R. & Tosh, D., Jun 2009, In: Gastroenterology. 136, 7, p. 2316-2324e3 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Zonation 100%
  • Catenin 83%
  • Wnt Signaling Pathway 66%
  • Glutamine Synthetase 66%
  • Oncogene C Myc 66%
  135 Citations (SciVal)

• Metaplasia and somatic cell reprogramming

  Slack, J., 2009, In: The Journal of Pathology. 217, 2, p. 161-168 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Metaplasia 100%
  • Somatic Cell 100%
  • Nuclear Reprogramming 100%
  • Transcription Factors 75%
  • Embryonic Stem Cell 50%
  28 Citations (SciVal)

• Protein rates of evolution are predicted by double-strand break events, independent of crossing-over rates

  Weber, C. C. & Hurst, L. D., Sept 2009, In: Genome biology and evolution. 2009, p. 340-349 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Crossing over 100%
  • Gene Expression 20%
  • Negative Selection (Natural Selection) 20%
  • Saccharomyces cerevisiae 20%
  • Gene Ontology 20%

• Reprogramming of liver to pancreas

  Thowfeequ, S., Li, W.-C., Slack, J. M. & Tosh, D., 2009, Stem Cells in Regenerative Medicine. Audet, J. & Stanford, W. L. (eds.). 482 ed. Humana Press, p. 407-418 12 p. (Methods in Molecular Biology).

  Research output: Chapter or section in a book/report/conference proceeding › Chapter or section

  • Beta Cell 100%
  • Allograft 100%
  • Transcription Factors 33%
  • Diabetes 33%
  • Hepatocyte 33%
  8 Citations (SciVal)

• Stripes and belly-spots: a review of pigment cell morphogenesis in vertebrates

  Kelsh, R. N., Harris, M. L., Colanesi, S. & Erickson, C. A., 2009, In: Seminars in Cell & Developmental Biology. 20, 1, p. 90-104

  Research output: Contribution to journal › Article › peer-review

  • Zebra Fish 100%
  • Chick 100%
  • Morphogenesis 100%
  • Pigment Cell 100%
  • Pattern Formation 80%
  159 Citations (SciVal)

• The price of silent mutations: Small changes to DNA that were once considered innocuous enough to be ignored are proving to be important in human diseases, evolution and biotechnology

  Chamary, J. V. & Hurst, L. D., 30 Jun 2009, In: Scientific American. 300, 6, p. 46-53 8 p.

  Research output: Contribution to journal › Article › peer-review
  64 Citations (SciVal)

• Why there is more to protein evolution than protein function: Splicing, nucleosomes and dual-coding sequence

  Warnecke, T., Weber, C. C. & Hurst, L. D., 2009, In: Biochemical Society Transactions. 37, 4, p. 756-761 6 p.

  Research output: Contribution to journal › Article › peer-review
  32 Citations (SciVal)
• 2008

  An evolutionarily conserved intronic region controls the spatiotemporal expression of the transcription factor Sox10

  Dutton, J. R., Antonellis, A., Carney, T. J., Rodriguez, F. S. L. M., Pavan, W. J., Ward, A. & Kelsh, R. N., 2008, In: BMC Developmental Biology. 8, 1, p. 105

  Research output: Contribution to journal › Meeting abstract › peer-review

  File

  • SOX10 100%
  • Transcription Factor Sox10 100%
  • Binding Site 75%
  • Neural Crest 75%
  • Zebra Fish 75%
  90 Citations (SciVal)

  176 Downloads (Pure)

• Determination of pelvic ring stability: a new technique using a composite hemi-pelvis

  Clements, J. P., Moriaty, N., Chesser, T. S., Ward, A. J. & Cunningham, J. L., 1 May 2008, In: Proceedings of the Institution of Mechanical Engineers, Part H - Journal of Engineering in Medicine. 222, 5, p. 611-616 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Degree of Freedom 100%
  • Implant 100%
  • Comparable Result 100%
  • Displacement Transducer 100%
  • Disruptions 100%
  11 Citations (SciVal)

• Do Alu repeats drive the evolution of the primate transcriptome?

  Urrutia, A. O., Ocana, L. B. & Hurst, L. D., 1 Feb 2008, In: Genome Biology. 9, 2, 16 p., R25.

  Research output: Contribution to journal › Article › peer-review

  File

  • Transcriptome 100%
  • CpG Island 100%
  • Transcription Factors 50%
  • Transcription 50%
  • Cell Function 50%
  18 Citations (SciVal)

  137 Downloads (Pure)