Conformational selection in Aurora-A kinase: competition between activator- and inhibitor- promoted forms

Search results

• 2019

  Ligand discrimination between active and inactive activation loop conformations of Aurora-A kinase is unmodified by phosphorylation

  Gilburt, J., Girvan, P., Blagg, J., Ying, L. & Dodson, C., 14 Apr 2019, In: Chemical Science. 10, 14, p. 4069-4076 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Conformation 100%
  • Aurora A Kinase 100%
  • Kinase 50%
  • Phosphotransferase 50%
  • Enzyme 12%

  8   Link opens in a new tab Citations (SciVal)

  16 Downloads (Pure)

• 2017

  Dynamic Equilibrium of the Aurora A Kinase Activation Loop Revealed by Single-Molecule Spectroscopy

  Gilburt, J., Sarkar, H., Sheldrake, P., Blagg, J., Ying, L. & Dodson, C., 6 Sept 2017, In: Angewandte Chemie International Edition. 56, 38, p. 11409-11414 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Conformation 100%
  • Aurora A Kinase 100%
  • Kinase 50%
  • Phosphotransferase 50%
  • TPX2 50%

  29   Link opens in a new tab Citations (SciVal)