Conformational selection in Aurora-A kinase: competition between activator- and inhibitor- promoted forms

Dodson, Charlotte (PI)

Department of Life Sciences

Project: Project at a former HEI

Short title	156908
Status	Finished
Effective start/end date	1/10/15 → 1/04/17

2 Article

Ligand discrimination between active and inactive activation loop conformations of Aurora-A kinase is unmodified by phosphorylation
Gilburt, J., Girvan, P., Blagg, J., Ying, L. & Dodson, C., 14 Apr 2019, In: Chemical Science. 10, 14, p. 4069-4076 8 p.
Research output: Contribution to journal › Article › peer-review

Open Access
6 Citations (SciVal)

16 Downloads (Pure)
Dynamic Equilibrium of the Aurora A Kinase Activation Loop Revealed by Single-Molecule Spectroscopy
Gilburt, J., Sarkar, H., Sheldrake, P., Blagg, J., Ying, L. & Dodson, C., 6 Sept 2017, In: Angewandte Chemie International Edition. 56, 38, p. 11409-11414 6 p.
Research output: Contribution to journal › Article › peer-review

Open Access
28 Citations (SciVal)

Single molecule experimental data for intensity histograms in Gilburt et al, Angewandte 2017
Dodson, C. (Creator), Gilburt, J. (Creator) & Ying, L. (Creator), Zenodo, 11 Jul 2017
DOI: 10.5281/zenodo.825693, https://DOI.org/10.5281/zenodo.825692
Dataset
Single molecule experimental data for dwell time histogram in Gilburt et al, Angewandte Chemie 2017
Dodson, C. (Creator), Gilburt, J. (Creator) & Ying, L. (Creator), Zenodo, 11 Jul 2017
DOI: 10.5281/zenodo.825752, https://DOI.org/10.5281/zenodo.825751
Dataset
Single molecule experimental data for unphosphorylated Aurora-A measurements in Gilburt et al, Chemical Science 2019
Dodson, C. (Creator), Gilburt, J. (Creator) & Ying, L. (Creator), Zenodo, 7 Mar 2019
DOI: 10.5281/zenodo.2555379
Dataset