BrainHealth - Decoding life course pathways of mental ageing - Frontier Research Guarantee

Research output

Research output per year 2024 2024 2025 2026

• 23 Article
• 1 Comment/debate
• 1 Letter
• 1 Review article

Research output per year

Research output per year

Search results

• 2026

  Consortium profile: the methylation, imaging and NeuroDevelopment (MIND) consortium

  Schuurmans, I. K., Mulder, R. H., Baltramonaityte, V., Lahtinen, A., Qiuyu, F., Rothmann, L., Staginnus, M., Tuulari, J. J., Burt, S. A., Buss, C., Craig, J. M., Donald, K. A., Eriksson, J. G., Felix, J. F., Freeman, T. P., Grassi-Oliveira, R., Huels, A., Hyde, L. W., jones, S. A. & Karlsson, H. & 26 others, Karlsson, L., Koen, N., Lawn, W., Mitchell, C., Monk, C. S., Mooney, M. A., Muetzel, R. L., Nigg, J. T., Iole Nogueira Belangero, S., Notterman, D. A., Ong, Y. Y., O'Connor, T., O’Donnell, K. J., Pan, P. M., Paunio, T., Ryabinin, P., Saffery, R., Salum, G. A., Seal, M., Silk, T. J., Stein, D. J., Tan, A. P., Wang, D., Zar, H. J., Walton, E. & Cecil, C. A. M., 28 Feb 2026, In: Molecular Psychiatry. 31, p. 1177-1189

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Methylation 100%
  • Nerve Cell Differentiation 100%
  • DNA Methylation 100%
  • Epigenomics 25%
  • Cross Sectional Study 25%

  3   Link opens in a new tab Citations (SciVal)

• Longitudinal co-development of mental and cardio-metabolic health from childhood to young adulthood

  Defina, S., Cecil, C. A. M., Felix, J. F., Walton, E. & Tiemeier, H., 31 Mar 2026, In: Journal of Child Psychology and Psychiatry. 67, 3, p. 413-424 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Economic and Social Development 100%
  • Body Mass Index 50%
  • Insulin 50%

• Orbitofrontal Thickness and Network Associations as Transdiagnostic Signature of Amotivation Along the Bipolar-Schizophrenia Spectrum

  Franz, M., Kebets, V., Berg, X., Georgiadis, F., Milano, B. A., Burrer, A., Brakowski, J., Kaiser, S., Seifritz, E., Homan, P., Walton, E., van Erp, T. G. M., Turner, J. A., Misic, B., Valk, S. L., Yeo, B. T. T., Bernhardt, B. C. & Kirschner, M., 31 Mar 2026, In: Schizophrenia Bulletin. 52, 2, sbaf078.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Orbitofrontal Cortex 100%
  • Schizophrenia 100%
  • Bipolar Disorder 50%
  • Negative Syndrome 50%
  • Cortical Region 10%

  3   Link opens in a new tab Citations (SciVal)

• Testing the Ecophenotype Hypothesis: Differences in White Matter Microstructure in Youth with Conduct Disorder With Versus Without a History of Childhood Abuse

  Townend, S., Staginnus, M., Rogers, J., Smaragdi, A., Martinelli, A., Bernhard, A., Raschle, N. M., Kohls, G., Konrad, K., Stadler, C., Freitag, C. M., Walton, E., De Brito, S. A. & Fairchild, G., 28 Feb 2026, In: Development and Psychopathology. 38, 1, p. 211-225 15 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Conduct Disorder 100%
  • Fractional Anisotropy 15%
  • Corpus Callosum 10%
  • Superior Longitudinal Fasciculus 5%
  • Diffusion Tensor Imaging 5%

• 2025

  A network analysis of housing quality indicators and depression in women

  Sanders, F., Waldren, L., Baltramonaityte, V., Lussier, A. A. & Walton, E., 5 Nov 2025, In: Scientific Reports. 15, 1, 8 p., 38745.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Network Analysis 100%
  • Housing Quality 100%
  • Emotions 100%
  • Mental Diseases 66%
  • Neurodevelopmental Disorder 66%

• Associations between epigenetic age and brain age in young people

  Sanders, F., Baltramonaityte, V., Donohoe, G., Davies, N. M., Dunn, E. C., Cecil, C. A. M. & Walton, E., 31 Dec 2025, In: Scientific Reports. 15, 1, 26609.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Neuroimaging 100%
  • Brain Age 100%
  • Body Mass Index 50%
  • Cognitive Function 50%
  • Mental Health 50%

• Biological pathways underlying the relationship between childhood maltreatment and Multimorbidity: A two-step, multivariable Mendelian randomisation study

  EarlyCause consortium, 31 May 2025, In: Brain Behavior and Immunity. 126, p. 59-69 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Mediator 100%
  • Biological Pathway 100%
  • Cortisol 66%
  • Genome-Wide Association Study 33%
  • Triglyceride 33%

  2   Link opens in a new tab Citations (SciVal)

• Genetic Susceptibility to Neurodevelopmental Conditions Is Associated With Neonatal DNA Methylation Patterns in the General Population: an individual participant data meta-analysis

  Schuurmans, I. K., Smajlagic, D., Baltramonaityte, V., Malmberg, A. L. K., Neumann, A., Creasey, N., Felix, J. F., Tiemeier, H., Pingault, J.-B., Czamara, D., Raïkkönen, K., Page, C. M., Lyle, R., Havdahl, A., Lahti, J., Walton, E., Bekkhus, M. & Cecil, C. A. M., 22 Sept 2025, (E-pub ahead of print) In: Biological Psychiatry.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Genetic Susceptibility 100%
  • DNA Methylation 100%
  • Methylation Pattern 100%
  • Polygenic Score 63%
  • Genetics 27%

  2   Link opens in a new tab Citations (SciVal)

• Home and Epigenome: Exploring the Role of DNA Methylation in the Relationship Between Poor Housing Quality and Depressive Symptoms

  Sanders, F., Baltramonaityte, V., Lussier, A. A., Smith, A., Dunn, E. C. & Walton, E., 15 Oct 2025, (E-pub ahead of print) In: BMJ Public Health. 3, 2, e002859.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • DNA Methylation 100%
  • Epigenome 100%
  • Risk Factor 100%

  40 Downloads (Pure)

• Interactive effects of genotype with prenatal stress on DNA methylation at birth

  Mulder, R. H., Baltramonaityte, V., Defina, S., Suderman, M., Boks, M. P., Walton, E., Cecil, C. A. M. & Felix, J. F., 24 Oct 2025, In: Molecular Psychiatry. 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Genotyping 100%
  • DNA Methylation 100%
  • Genetic Divergence 40%
  • Genetic Model 10%
  • Gene Linkage 10%

  2   Link opens in a new tab Citations (SciVal)

• Lifestyle behaviours do not moderate the association between childhood maltreatment and comorbid depression and cardiometabolic disease in older adults: a meta-analysis

  Layinka, J., Souama, C., Defina, S., Baltramonaityte, V., Cecil, C. A. M., Shah, P., Milaneschi, Y., Lamers, F., Penninx, B. W. J. H. & Walton, E., 31 Dec 2025, In: BMC medicine. 23, 1, 133.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Meta-Analysis 100%
  • Childhood Maltreatment 100%
  • Comorbidity 57%
  • Physical Activity 28%
  • Health Concern 14%

  1   Link opens in a new tab Citation (SciVal)

• Shared and distinct alterations in brain structure of youth with internalizing or externalizing disorders: Findings from the ENIGMA Antisocial Behavior, ADHD, MDD, and Anxiety Working Groups

  Sophie Townend, Staginnus, M., Gao, Y., Alexander, N., Arolt, V., Banaschewski, T., Beesdo-Baum, K., Bellgrove, M. A., Benegal, V., Blair, R. J., Blanco-Hinojo, L., Boeken, O. J., Böhnlein, J., Bölte, S., Bonnekoh, L. M., Brandeis, D., Bressan, R. A., Breuer, F., Bruin, W. B. & Buitelaar, J. K. & 134 others, Burkhouse, K. L., Calkins, M. E., Cano, M., Cardoner, N., Chen, H., Chen, X., Coghill, D. R., Colins, O. F., Connolly, C. G., Craig, M. C., Cullen, K. R., Dannlowski, U., Davey, C. G., Dietrich, A., Dong, D., Freitag, C. M., Frodl, T., Goossens, L., Grotegerd, D., Gur, R. E., Gur, R. C., Haavik, J., Hagan, C. C., Hahn, T., Hamm, A. O., Harrison, B. J., Hartman, C. A., Herrmann, M. J., Ho, T. C., Hoekstra, P. J., Holla, B., Ibrahim, K., Jackowski, A., Jamalabadi, H., Jiang, Y., Kircher, T., Konrad, K., Kraus, A., Kuntsi, J., Langhammer, T., Lazaro, L., Leehr, E. J., Lueken, U., Ma, R., MacMaster, F. P., Manfro, G. G., Martinelli, A., Meinert, H., Meinert, S., Michałowski, J. M., Ming, Q., Moeck, R., Muehlhan, M., Mujica-Parodi, L. R., Mwangi, B., Neufeld, J., Nigg, J. T., O’Gorman Tuura, R. L., Oh, H., Oosterlaan, J., Paloyelis, Y., Pan, P. M., Passamonti, L., Peñate, W., Phan, K. L., Plessen, K. J., Pujol, J., Remnélius, K. L., Rivero, F., Rubia, K., Salas, R., Salum, G. A., Satterthwaite, T. D., Schienle, A., Schrammen, E., Schruers, K. R. J., Schumann, G., Sethi, A., Silk, T., Skokauskas, N., Smoller, J. W., Soares, J. C., Sørensen, L., Stadler, C., Stevens, M. C., Straube, B., Straube, T., Ströhle, A., Sudre, G., Sukhodolsky, D. G., Sully, K., Sun, X., Sylvester, C. M., Toschi, N., van der Werff, S. J. A., Vance, A., Vermeiren, R., Wabnegger, A., Wang, X., Wendt, J., Whittle, S., Wiemer, J., Winkler, A. M., Wittchen, H. U., Wu, M.-J., Wu, Q., Yang, T. T., Yang, Y., Yao, S., Zhang, J., Zhou, J., Zugman, A., Zunta-Soares, G. B., Zwanzger, P. M., Thomopoulos, S. I., Jahanshad, N., Thompson, P. M., Hilbert, K., Baskin-Sommers, A., Cecil, C. A. M., Aghajani, M., Pine, D. S., van der Wee, N. J. A., Stein, D. J., Groenewold, N. A., Bas-Hoogendam, J. M., Han, L. K. M., Pozzi, E., Schmaal, L., Franke, B., Hoogman, M., Walton, E., De Brito, S. A. & Fairchild, G., 15 Aug 2025, In: Biological Psychiatry. 100, 4, p. 399-413

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Behavior (Neuroscience) 100%
  • Attention Deficit Hyperactivity Disorder 100%
  • Brain Structure 100%
  • Conduct Disorder 75%
  • Anxiety Disorder 75%

• Strengthening Rigor and Reproducibility in Epigenome-Wide Association Studies of Social Exposures and Brain-Based Health Outcomes

  McKenna, B. G., Lussier, A. A., Suderman, M. J., Walton, E., Simpkin, A. J., Hüls, A. & Dunn, E. C., 21 Apr 2025, In: Current Environmental Health Reports. 12, 1, 19.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Reproducibility 100%
  • Health Outcomes 100%
  • Rigor 100%
  • Epigenomics 100%
  • Mental Capacity 20%

  2   Link opens in a new tab Citations (SciVal)

• Stress reactivity moderates the association between stressful life events and depressive symptoms in adolescents: Results from a population-based study

  Baltramonaityte, V., Lussier, A. A., Smith, A. D. A. C., Simpkin, A. J., Fairchild, G., Dunn, E. C. & Walton, E., 15 Mar 2025, In: Journal of Affective Disorders. 373, p. 28-34 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Adolescence 100%
  • Stress Reactivity 100%
  • Stressful Life Event 100%
  • Life Event 28%
  • Regression Analysis 14%

  2   Link opens in a new tab Citations (SciVal)

• The association between epigenetic ageing from childhood to early adulthood and psychotic-like experiences in early adulthood

  Hart, Z., Großbach, A., Simpkin, A. J. & Walton, E., 30 Jun 2025, In: Psychological Medicine. 55, p. 1-9 e182.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • DNA Methylation 100%
  • Cognitive Defect 100%
  • Premature Mortality 100%
  • Longitudinal Study 100%
  • Early Adulthood 100%

• 2024

  Are housing circumstances associated with faster epigenetic ageing? A commentary on Clair et al

  Sanders, F., Walton, E. & Lussier, A. A., 7 Jun 2024, In: Journal of Epidemiology & Community Health.

  Research output: Contribution to journal › Letter › peer-review

  Open Access

  File

  192 Downloads (Pure)

• Assessing the association between global structural brain age and polygenic risk for schizophrenia in early adulthood: A recall-by-genotype study

  Constantinides, C., Baltramonaityte, V., Caramaschi, D., Han, L. K. M., Lancaster, T., Zammit, S., Freeman, T. & Walton, E., 31 Mar 2024, In: Cortex. 172, p. 1-13 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Brain Age 100%
  • Schizophrenia 100%
  • Genetics 28%
  • Gray Matter 14%
  • Magnetic Resonance Imaging 14%

  5   Link opens in a new tab Citations (SciVal)

• Cortical structure and subcortical volumes in conduct disorder: a coordinated analysis of 15 international cohorts from the ENIGMA-Antisocial Behavior Working Group

  Gao, Y., Staginnus, M. & ENIGMA-Antisocial Behavior Working Group, 31 Aug 2024, In: The Lancet Psychiatry. 11, 8, p. 620-632 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Behavior (Neuroscience) 100%
  • Conduct Disorder 100%
  • Cortical Thickness 15%
  • Mental Disorder 7%
  • Amygdala 7%

  23   Link opens in a new tab Citations (SciVal)

• DNA methylation at birth and lateral ventricular volume in childhood: a neuroimaging epigenetics study

  Luo, M., Walton, E., Neumann, A., Thio, C. H. L., Felix, J. F., van IJzendoorn, M. H., Pappa, I. & Cecil, C. A. M., 31 Jan 2024, In: Journal of Child Psychology and Psychiatry. 65, 1, p. 77-90 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Epigenomics 100%
  • DNA Methylation 100%
  • Epigenetics 100%
  • Methylation 33%
  • Ciliogenesis 11%

  7   Link opens in a new tab Citations (SciVal)

• Effects of Pre- and Postnatal Early-Life Stress on Internalizing, Adiposity and Their Comorbidity

  EarlyCause consortium, 29 Feb 2024, In: Journal of the American Academy of Child and Adolescent Psychiatry. 63, 2, p. 255-265 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Comorbidity 100%
  • Internalizing 100%
  • Internalizing Symptom 50%
  • Adolescence 25%
  • Prenatal Stress 25%

  12   Link opens in a new tab Citations (SciVal)

• Gestational epigenetic age and ADHD symptoms in childhood: a prospective, multi-cohort study

  Salontaji, K., Haftorn, K. L., Sanders, F., Page, C. M., Walton, E., Felix, J. F., Bekkhus, M., Bohlin, J., Tiemeier, H. & Cecil, C. A. M., 30 Sept 2024, In: Molecular Psychiatry. 29, 9, p. 2911-2918 8 p.

  Research output: Contribution to journal › Comment/debate › peer-review

  • Attention Deficit Hyperactivity Disorder 100%
  • Gestational Age 62%
  • Longitudinal Analysis 12%

  5   Link opens in a new tab Citations (SciVal)

• Mapping prenatal predictors and neurobehavioral outcomes of an epigenetic marker of neonatal inflammation – A longitudinal population-based study

  Suleri, A., Creasey, N., Walton, E., Muetzel, R., Felix, J. F., Duijts, L., Bergink, V. & Cecil, C. A. M., 30 Nov 2024, In: Brain, Behavior, and Immunity. 122, p. 483-496 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Methylation 100%
  • Epigenetic Marker 100%
  • Inflammation 100%
  • Offspring 100%
  • Psychopathology 100%

  8   Link opens in a new tab Citations (SciVal)

• Maximizing insights from longitudinal epigenetic age data: simulations, applications, and practical guidance

  Großbach, A., Suderman, M. J., Hüls, A., Lussier, A. A., Smith, A. D. A. C., Walton, E., Dunn, E. C. & Simpkin, A. J., 20 Dec 2024, In: CLINICAL EPIGENETICS. 16, 1, p. 187 187.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Mixed Model 100%

  2   Link opens in a new tab Citations (SciVal)

• The role of lifestyle factors in the association between early-life stress and adolescent psycho-physical health: Moderation analysis in two European birth cohorts

  Defina, S., Woofenden, T., Baltramonaityte, V., Tiemeier, H., Fairchild, G., Felix, J. F., Cecil, C. A. M. & Walton, E., 31 May 2024, In: Preventive Medicine. 182, 107926.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Comorbidity 100%
  • Adolescence 100%
  • Physical Activity 66%
  • Mental Health 33%
  • Healthy Lifestyle 16%

  4   Link opens in a new tab Citations (SciVal)

• The Role of Loneliness and Social Isolation in Mediating the Relationship Between Childhood Maltreatment and Schizophrenia: A Genetically Informed Approach

  Zavitsanou, G., Waldren, L. H., Walton, E. & Baltramonaityte, V., 9 May 2024, In: Journal of Psychopathology and Clinical Science. 133, 5, p. 392-402 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Schizophrenia 100%
  • Loneliness 100%
  • Childhood Maltreatment 100%
  • Social Isolation 100%
  • Social Alienation 100%

  1   Link opens in a new tab Citation (SciVal)

  141 Downloads (Pure)

• Transient patterns of advanced brain ageing in female adolescents with Anorexia Nervosa

  Stratton, T., Bahnsen, K., Geisler, D., Bernardoni, F., Gaser, C., Ehrlich, S. & Walton, E., 30 Nov 2024, In: The British Journal of Psychiatry. 225, 5, p. 499-505

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Anorexia Nervosa 100%
  • Brain Age 100%
  • Gray Matter 75%
  • Psychopathology 50%
  • Magnetic Resonance Imaging 25%

  5   Link opens in a new tab Citations (SciVal)