AMACR Targeted Drugs for Treating Advance Prostate Cancer

James, Tony (PI)

Project: UK charity

Status	Finished
Effective start/end date	1/02/15 → 31/01/18

Funding

Prostate Cancer UK

4 Poster
4 Article
1 Abstract
1 Review article

Racemases and epimerases operating through a 1,1-proton transfer mechanism: Reactivity, mechanism and inhibition
Lloyd, M., Jevglevskis, M., Nathubhai, A., James, T., Threadgill, M. & Woodman, T., 1 May 2021, In: Chemical Society Reviews. 50, 10, p. 5952–5984 33 p.
Research output: Contribution to journal › Review article › peer-review

Open Access
22 Link opens in a new tab Citations (SciVal)
Identification of novel small-molecule inhibitors of α-methylacyl-CoA racemase (AMACR; P504S) and structure-activity relationships
Petrova, Y., Wadda, K., Nathubhai, A., Jevglevskis, M., Mitchell, P., James, T., Threadgill, M., Woodman, T. & Lloyd, M., 1 Nov 2019, In: Bioorganic Chemistry. 92, 103264.
Research output: Contribution to journal › Article › peer-review

Open Access
File
14 Link opens in a new tab Citations (SciVal)

203 Downloads (Pure)
Novel 2-arylthiopropanoyl-CoA inhibitors of α-methylacyl-CoA racemase 1A (AMACR; P504S) as potential anti-prostate cancer agents
Jevglevskis, M., Nathubhai, A., Wadda, K., Lee, G. L., Al-Rawi, S., Jiao, T., Mitchell, P., James, T., Threadgill, M., Woodman, T. & Lloyd, M., 1 Nov 2019, In: Bioorganic Chemistry. 92, 103263.
Research output: Contribution to journal › Article › peer-review

Open Access
File
13 Link opens in a new tab Citations (SciVal)

353 Downloads (Pure)