Zoe Burke

Dr

20042018
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Research Output 2004 2018

2018

Spatiotemporal regulation of liver development by the Wnt/β-catenin pathway

Burke, Z. D., Reed, K. R., Yeh, S-W., Meniel, V., Sansom, O. J., Clarke, A. R. & Tosh, D., 9 Feb 2018, In : Scientific Reports. 8, 1, p. 1-9 9 p., 2735.

Research output: Contribution to journalArticle

Open Access
beta Catenin
Glutamate-Ammonia Ligase
Liver
Ammonia
Carbamoyl-Phosphate Synthase (Ammonia)
2017
8 Citations (Scopus)
34 Downloads (Pure)

Hnf4α is a key gene that can generate columnar metaplasia in oesophageal epithelium

Colleypriest, B. J., Burke, Z. D., Griffiths, L. P., Chen, Y., Yu, W-Y., Jover, R., Bock, M., Biddlestone, L., Quinlan, J. M., Ward, S. G., Mark Farrant, J., Slack, J. M. W. & Tosh, D., 1 Jan 2017, In : Differentiation. 93, p. 39-49 11 p.

Research output: Contribution to journalArticle

Open Access
File
Barrett Esophagus
Metaplasia
Organ Culture Techniques
Epithelium
Phenotype
2015
22 Citations (Scopus)

MicroRNA-122: A novel hepatocyte-enriched in vitro marker of drug-induced cellular toxicity

Kia, R., Kelly, L., Sison-Young, R. L. C., Zhang, F., Pridgeon, C. S., Heslop, J. A., Metcalfe, P., Kitteringham, N. R., Baxter, M., Harrison, S., Hanley, N. A., Burke, Z. D., Storm, M. P., Welham, M. J., Tosh, D., Küppers-Munther, B., Edsbagge, J., Starkey Lewis, P. J., Bonner, F., Harpur, E. & 6 others, Sidaway, J., Bowes, J., Fenwick, S. W., Malik, H., Goldring, C. E. P. & Kevin Park, B., Mar 2015, In : Toxicological Sciences. 144, 1, p. 173-185 13 p.

Research output: Contribution to journalArticle

MicroRNAs
Toxicity
Hepatocytes
Assays
Pharmaceutical Preparations
2012
22 Citations (Scopus)
Barrett Esophagus
Metaplasia
Esophagus
Epithelium
Esophageal Diseases
1 Citation (Scopus)

Cellular Reprogramming During Mouse Development

Burke, Z. D., Miron-Buchacra, G. & Tosh, D., 2012, Mouse Development. Kubiak, J. Z. (ed.). Berlin: Springer, p. 291-302

Research output: Chapter in Book/Report/Conference proceedingChapter

Switch Genes
Developmental Biology
Regenerative Medicine
Cellular Reprogramming
Cell Differentiation
7 Citations (Scopus)

Ontogenesis of Hepatic and Pancreatic Stem Cells

Burke, Z. D. & Tosh, D., 2012, In : Stem Cell Reviews and Reports. 8, 2, p. 586-596

Research output: Contribution to journalArticle

Pancreas
Stem Cells
Liver
Embryonic Structures
Endoderm
2010
18 Citations (Scopus)

Dexamethasone treatment induces the reprogramming of pancreatic acinar cells to hepatocytes and ductal cells

Al-Adsani, A., Burke, Z. D., Eberhard, D., Lawrence, K. L., Shen, C. N., Rustgi, A. K., Sakaue, H., Farrant, J. M. & Tosh, D., 27 Oct 2010, In : PLoS ONE. 5, 10, 12 p., e13650.

Research output: Contribution to journalArticle

acinar cells
Acinar Cells
dexamethasone
Dexamethasone
hepatocytes
58 Citations (Scopus)
73 Downloads (Pure)

Genetic dissection of differential signaling threshold requirements for the Wnt/β-Catenin pathway in vivo

Buchert, M., Athineos, D., Abud, H. E., Burke, Z. D., Faux, M. C., Samuel, M. S., Jarnicki, A. G., Winbanks, C. E., Newton, I. P., Meniel, V. S., Suzuki, H., Stacker, S. A., Nathke, I. S., Tosh, D., Huelsken, J., Clarke, A. R., Heath, J. K., Sansom, O. J. & Ernst, M., 15 Jan 2010, In : Plos Genetics. 6, 1, e1000816.

Research output: Contribution to journalArticle

File
Differential Threshold
dissection
beta Catenin
phenotype
Dissection
4 Citations (Scopus)

In vitro reprogramming of pancreatic cells to hepatocytes

Eberhard, D., O’Neill, K., Burke, Z. D. & Tosh, D., 2010, Cellular Programming and Reprogramming: Methods and Protocols. Ding, S. (ed.). 636 ed. Humana Press, p. 285-292 8 p. (Methods in Molecular Biology).

Research output: Chapter in Book/Report/Conference proceedingChapter

Hepatocytes
Glucocorticoids
Liver
Xenobiotics
Dexamethasone
4 Citations (Scopus)

Isolation and culture of embryonic pancreas and liver

Burke, Z. D., Li, W-C., Slack, J. & Tosh, D., 2010, Mouse Cell Culture: Methods and Protocols. Ward, A. & Tosh, D. (eds.). 633 ed. Humana Press, p. 91-99 9 p. (Methods in Molecular Biology).

Research output: Chapter in Book/Report/Conference proceedingChapter

Pancreas
Liver
Embryonic Structures
Organogenesis
Fibronectins
2009
88 Citations (Scopus)

Liver zonation occurs through a β-catenin–dependent, c-Myc–independent mechanism

Burke, Z. D., Reed, K. R., Phesse, T. J., Sansom, O. J., Clarke, A. R. & Tosh, D., Jun 2009, In : Gastroenterology. 136, 7, p. 2316-2324e3 9 p.

Research output: Contribution to journalArticle

beta Catenin
Glutamate-Ammonia Ligase
Wnt Signaling Pathway
Carbamoyl-Phosphate Synthase (Ammonia)
Liver
2008
50 Citations (Scopus)

B-catenin deficiency, but not Myc deletion, suppresses the immediate phenotypes of APC loss in the liver

Reed, K. R., Athineos, D., Meniel, V. S., Wilkins, J. A., Ridgway, R. A., Burke, Z. D., Muncan, V., Clarke, A. R. & Sansom, O. J., 2008, In : Proceedings of the National Academy of Sciences of the United States of America. 105, 48, p. 18919-18923 5 p.

Research output: Contribution to journalArticle

Catenins
beta Catenin
Phenotype
Hepatomegaly
Liver
2007

Sources of hepatocytes for transplantation in hepatic dysfunction

Ralphs, K. L., Li, W-C., Burke, Z. D., Thowfeequ, S., Al-Adsani, A. & Tosh, D., 2007, In : Journal of Organ Dysfunction. 3, 3, p. 150-163 14 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)

Stem cells in the adult pancreas and liver

Burke, Z. D., Thowfeequ, S., Peran, M. & Tosh, D., 2007, In : Biochemical Journal. 404, p. 169-178 10 p.

Research output: Contribution to journalArticle

Adult Stem Cells
Stem cells
Liver
Pancreas
Stem Cells
2006
32 Citations (Scopus)

C/EBP alpha and C/EBP beta are markers of early liver development

Westmacott, A., Burke, Z. D., Oliver, G., Slack, J. M. W. & Tosh, D., 2006, In : International Journal of Developmental Biology. 50, 7, p. 653-657 5 p.

Research output: Contribution to journalArticle

CCAAT-Enhancer-Binding Protein-alpha
CCAAT-Enhancer-Binding Protein-beta
Liver
Pancreas
Hepatocytes
37 Citations (Scopus)

Characterization of liver function in transdifferentiated hepatocytes

Burke, Z. D., Shen, C. N., Ralphs, K. L. & Tosh, D., Jan 2006, In : Journal of Cellular Physiology. 206, 1, p. 147-159 13 p.

Research output: Contribution to journalArticle

Liver
Hepatocytes
CCAAT-Enhancer-Binding Protein-beta
Transcription Factors
Cells
9 Citations (Scopus)

Liver specification: A new role for Wnts in liver development

Burke, Z. D., Thowfeequ, S. & Tosh, D., Nov 2006, In : Current Biology. 16, 17, p. R688-R690

Research output: Contribution to journalArticle

37 Citations (Scopus)

The Wnt/beta-catenin pathway: master regulator of liver zonation?

Burke, Z. D. & Tosh, D., Nov 2006, In : Bioessays. 28, 11, p. 1072-1077 6 p.

Research output: Contribution to journalArticle

Glutamate-Ammonia Ligase
beta Catenin
Ammonia
Liver
Urea
2005
52 Citations (Scopus)

The molecular basis of transdifferentiation

Li, W. C., Yu, W. Y., Quinlan, J. M., Burke, Z. D. & Tosh, D., Jul 2005, In : Journal of Cellular and Molecular Medicine. 9, 3, p. 569-582 14 p.

Research output: Contribution to journalArticle

Phenotype
Developmental Biology
Metaplasia
Transcription Factors
Stem Cells
30 Citations (Scopus)

Therapeutic potential of transdifferentiated cells

Burke, Z. D. & Tosh, D., 2005, In : Clinical Science. 108, 4, p. 309-321 13 p.

Research output: Contribution to journalArticle

Adult Stem Cells
Embryonic Stem Cells
Cell- and Tissue-Based Therapy
Therapeutics
Parkinson Disease
2004
13 Citations (Scopus)

Bile ducts as a source of pancreatic beta cells

Burke, Z. D., Shen, C. N. & Tosh, D., Sep 2004, In : Bioessays. 26, 9, p. 932-937 6 p.

Research output: Contribution to journalArticle

Insulin-Secreting Cells
Bile Ducts
Liver
Ducts
Pancreas