Projects per year
Personal profile
Research interests
I am a consultant rheumatologist at the Royal National Hospital for Rheumatic Diseases and senior lecturer in the department of Pharmacy and Pharmacology. I graduated from the University of Bristol with a BSc in Anatomical Science before undertaking my medical degree at the same institution.
My research interests centre on improving the assessment and treatment of psoriatic arthritis. Psoriatic arthritis is a form of arthritis that affects approximately one in five people living with psoriasis causing pain, stiffness and damage to the joints, tendons and spine. Left untreated psoriatic arthritis causes significant pain, reduced function, impaired quality of life and work disability.
The overarching aim of my research is to improve the lives of people living with arthritis through improved detection (diagnosis), assessment (patient reported, clinical and imaging) and treatment strategies. I work with industry, the NHS, charities and across university departments to answer clinically important questions. My current research interests focus on:
- Early detection of disease and enhanced surveillance to improve outcome
- Precision medicine through improved treatment selection, refining composite measures to improve assessment and treatment strategies
- Understanding the natural course of disease, prognosis and evolution of damage
- Effect of biologics and targeted synthetic drugs in PsA
I am accepting students who would like to undertake research projects of any duration up to and including PhD studies. I also welcome collaborations from other disciplines where there is an opportunity to advance knowledge across specialities.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Psoriatic Arthritis, Doctor of Science, University of Bath
Anatomical Science, Bachelor of Science, University of Bristol
Medicine, Bachelor of Medicine and Bachelor of Surgery, University of Bristol
External positions
Consultant Rheumatologist, Royal National Hospital for Rheumatic Diseases
1 Aug 2014 → …
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Collaborations and top research areas from the last five years
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Medication use during pregnancy in women with chronic inflammatory disease
McGrogan, A. (PI), Charlton, R. (CoI) & Tillett, W. (CoI)
Bath Institute For Rheumatic Diseases
1/01/22 → 31/12/24
Project: UK charity
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Automated Image Recognition in Psoriatic Arthritis: AI-PsA
Tillett, W. (PI)
Royal United Hospitals Bath NHS Foundation Trust
1/06/20 → 1/11/25
Project: Central government, health and local authorities
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The Assessment of Structural Damage in Psoriatic Arthritis
Tillett, W. (PI)
1/05/14 → …
Project: Central government, health and local authorities
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The total burden of psoriasis
McHugh, N. (PI) & Tillett, W. (CoI)
Royal United Hospitals Bath NHS Foundation Trust
1/05/23 → 30/04/24
Project: Central government, health and local authorities
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Association of achieving clinical disease control criteria and patient-reported outcomes in bimekizumab-treated patients with active psoriatic arthritis: results from two phase III studies
Kristensen, L. E., Tillett, W., Nash, P., Coates, L. C., Mease, P. J., Ogdie, A., Gisondi, P., Ink, B., Prickett, A. R., Bajracharya, R., Taieb, V., Lyris, N., Lambert, J. & Walsh, J. A., 31 Dec 2024, In: Therapeutic Advances in Musculoskeletal Disease. 16Research output: Contribution to journal › Article › peer-review
Open Access -
Bimekizumab provided rapid improvements in patient-reported symptoms and health-related quality of life in patients with active psoriatic arthritis: pooled 16-week results from two phase 3 studies
Husni, M. E., Mease, P. J., Merola, J. F., Tillett, W., Goldammer, N., Ink, B., Coarse, J., Lambert, J., Taieb, V. & Gladman, D. D., 23 Sept 2024, In: RMD Open. 10, 3, 11 p., e004464.Research output: Contribution to journal › Article › peer-review
Open Access -
Changing medication-related beliefs: A systematic review and meta-analysis of randomized controlled trials
Sheils, E., Tillett, W., James, D., Brown, S., Dack, C., Family, H. & Chapman, S. C. E., 31 Mar 2024, In: Health Psychology. 43, 3, p. 155-170 16 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Citations (SciVal)161 Downloads (Pure) -
Comparative early effectiveness across 14 PsA drugs and 5 classes of PsA treatment: 3-month results from the PRO-SPIRIT study
Kristensen, L. E., Ng, K. J., Ngantcha, M., Morel, J., Lubrano, E., Tillett, W., Alten, R., Chandran, V., Martinez Ferrer, À., Zhu, B., Kennedy, D., Holzkämper, T., Gullick, N., Kronbergs, A., Fakhouri, W., de la Torre, I. & McGonagle, D. G., 20 Sept 2024, In: RMD Open. 10, 3, e004318.Research output: Contribution to journal › Article › peer-review
Open Access -
Composite Outcome Measures for Psoriatic Arthritis: OMERACT and 3 and 4 Visual Analog Scale Progress in 2023
Leung, Y. Y., Gladman, D. D., Orbai, A.-M. & Tillett, W., 1 Oct 2024, In: The Journal of Rheumatology. 51, Suppl 2, p. 80-83Research output: Contribution to journal › Article › peer-review
1 Citation (SciVal)
Thesis
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Work Disability in Psoriatic Arthritis
Tillett, W. (Author)McHugh, N. (Supervisor), 2 Jul 2014Student thesis: Doctoral Thesis › PhD
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