Vasanta Subramanian

2024

Neural stem cell homeostasis is affected in cortical organoids carrying a mutation in Angiogenin

Ferguson, R., van Es, M. A., Van den Berg, L. H. & Subramanian, V., 30 Apr 2024, In: The Journal of Pathology. 262, 4, p. 410-426 17 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Citations (SciVal)

Targeted Deletion in the Basal Body Protein Talpid3 Leads to Loss of Primary Cilia in Embryonic Stem Cells and Defective Lineage-Specific Differentiation

Ferguson, R. & Subramanian, V., 31 Dec 2024, In: Cells. 13, 23, 1957.

Research output: Contribution to journal › Article › peer-review

Open Access

2022

Hippocampals neurogenesis is impaired in mice with a deletion in the coiled coil domain of Talpid3-implications for Joubert syndrome

Bashford, A. & Subramanian, V., 29 Sept 2022, In: Human Molecular Genetics. 31, 19, p. 3245-3265 21 p., ddac095.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Citation (SciVal)

2020

Crystal structure of peptide-bound neprilysin reveals key binding interactions

Moss, S., Subramanian, V. & Acharya, K. R., 29 Feb 2020, In: FEBS Letters. 594, 2, p. 327-336 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

12 Citations (SciVal)

86 Downloads (Pure)

2019

Mice with a conditional deletion of Talpid3 (KIAA0586) - a model for Joubert Syndrome

Bashford, A. L. & Subramanian, V., 18 Jul 2019, In: The Journal of Pathology. 248, 4, p. 396-408 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

21 Citations (SciVal)

The catalytic activity and secretion of zebrafish RNases are essential for their in vivo function in motor neurons and vasculature

Ferguson, R., Holloway, D. E., Chandrasekhar, A., Acharya, K. R. & Subramanian, V., 1 Feb 2019, In: Scientific Reports. 9, 1, p. 1-15 15 p., 1107.

Research output: Contribution to journal › Article › peer-review

Open Access

11 Citations (SciVal)

The secretion of the angiogenic and neurotrophic factor angiogenin is COPII and microtubule dependent

Ferguson, R. & Subramanian, V., 15 Aug 2019, In: Experimental Cell Research. 381, 2, p. 265-279 15 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

1 Citation (SciVal)

118 Downloads (Pure)

2018

A comparative bioinformatic analysis of C9orf72

Iyer, S., Acharya, K. R. & Subramanian, V., 19 Feb 2018, In: PeerJ. 6, 2, p. e4391 e4391.

Research output: Contribution to journal › Article › peer-review

Open Access

12 Citations (SciVal)

C9orf72, a protein associated with amyotrophic lateral sclerosis (ALS) is a guanine nucleotide exchange factor

Iyer, S., Subramanian, V. & Acharya, K. R., 17 Oct 2018, In: PeerJ. p. 1-29 29 p., e5815.

Research output: Contribution to journal › Article › peer-review

Open Access

45 Citations (SciVal)

Embryoid body arrays: Parallel cryosectioning of spheroid/embryoid body samples for medium through-put analysis

Ferguson, R. & Subramanian, V., 1 Apr 2018, In: Stem Cell Research. 28, p. 125-130 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

4 Citations (SciVal)

High resolution crystal structure of substrate-free human neprilysin

Moss, S., Subramanian, V. & Acharya, K. R., 1 Oct 2018, In: Journal of Structural Biology. 204, 1, p. 19-25 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

18 Citations (SciVal)

167 Downloads (Pure)

Prediction of structural consequences for disease causing variants in C21orf2 protein using computational approaches

Iyer, S., Acharya, K. R. & Subramanian, V., 7 Feb 2018, (E-pub ahead of print) In: Journal of Biomolecular Structure & Dynamics. p. 1-16 16 p.

Research output: Contribution to journal › Article › peer-review

5 Citations (SciVal)

The cellular uptake of angiogenin, an angiogenic and neurotrophic factor is through multiple pathways and largely dynamin independent

Ferguson, R. & Subramanian, V., 27 Feb 2018, In: PLoS ONE. 13, 2, p. e0193302 e0193302.

Research output: Contribution to journal › Article › peer-review

Open Access

15 Citations (SciVal)

2017

Structural insights into human angiogenin variants implicated in Parkinson's disease and Amyotrophic Lateral Sclerosis

Bradshaw, W. J., Rehman, S., Pham, T. T. K., Thiyagarajan, N., Lee, R. L., Subramanian, V. & Acharya, K. R., 8 Feb 2017, In: Scientific Reports. 7, p. 1-10 10 p., 41996.

Research output: Contribution to journal › Article › peer-review

Open Access

34 Citations (SciVal)

2016

Dynamic expression of the mouse orthologue of the human amyotropic lateral sclerosis associated gene C9orf72 during central nervous system development and neuronal differentiation

Ferguson, R., Serafeimidou-Pouliou, E. & Subramanian, V., Dec 2016, In: Journal Of Anatomy. 229, 6, p. 871-891

Research output: Contribution to journal › Article › peer-review

Open Access

File

6 Citations (SciVal)

92 Downloads (Pure)

PA6 Stromal Cell Co-Culture Enhances SH-SY5Y and VSC4.1 Neuroblastoma Differentiation to Mature Phenotypes

Ferguson, R. & Subramanian, V., 8 Jul 2016, In: PLoS ONE. 11, 7, e0159051.

Research output: Contribution to journal › Article › peer-review

Open Access

File

16 Citations (SciVal)

391 Downloads (Pure)

2012

Structural and molecular insights into the mechanism of action of human angiogenin-ALS variants in neurons.

Thiyagarajan, N., Ferguson, R., Subramanian, V. & Acharya, K. R., 9 Oct 2012, In: Nature Communications. 3, 14 p., 1121.

Research output: Contribution to journal › Article › peer-review

79 Citations (SciVal)

2008

Human angiogenin is a neuroprotective factor and amyotrophic lateral sclerosis associated angiogenin variants affect neurite extension/pathfinding and survival of motor neurons

Subramanian, V., Crabtree, B. & Acharya, K. R., 1 Jan 2008, In: Human Molecular Genetics. 17, 1, p. 130-149 20 p.

Research output: Contribution to journal › Article › peer-review

113 Citations (SciVal)

Ribonuclease A homologues of the zebrafish: polymorphism, crystal structures of two representatives and their evolutionary implications

Kazakou, K., Holloway, D. E., Prior, S. H., Subramanian, V. & Acharya, K. R., 27 Jun 2008, In: Journal of Molecular Biology. 380, 1, p. 206-222 17 p.

Research output: Contribution to journal › Article › peer-review

22 Citations (SciVal)

2007

A new role for angiogenin in neurite growth and pathfinding: implications for amyotrophic lateral sclerosis

Subramanian, V. & Feng, Y., Jun 2007, In: Human Molecular Genetics. 16, p. 1445--1453 9 p.

Research output: Contribution to journal › Article › peer-review

73 Citations (SciVal)

Behaviour of endothelial cells on Matrigel and development of a method for a rapid and reproducible in vitro angiogenesis assay

Crabtree, B. & Subramanian, V., Feb 2007, In: In Vitro Cellular & Developmental Biology - Animal. 43, p. 87--94 8 p.

Research output: Contribution to journal › Article › peer-review

20 Citations (SciVal)

Biological and structural features of murine angiogenin-4, an angiogenic protein

Crabtree, B., Holloway, D. E., Baker, M. D., Acharya, K. R. & Subramanian, V., 2007, In: Biochemistry. 46, 9, p. 2431-2443 13 p.

Research output: Contribution to journal › Article › peer-review

37 Citations (SciVal)

Characterization of human angiogenin variants implicated in amyotrophic lateral sclerosis

Crabtree, B., Thiyagarajan, N., Prior, S. H., Wilson, P., Iyer, S., Ferns, T., Shapiro, R., Brew, K., Subramanian, V. & Acharya, K. R., 2007, In: Biochemistry. 46, 42, p. 11810-11818 9 p.

Research output: Contribution to journal › Article › peer-review

92 Citations (SciVal)

2005

Investigating the potential functions of murine Angiogenin 4

Crabtree, B., Acharya, K. R. & Subramanian, V., 2005, In: Genetics Research. 86, 3, p. 234-234 1 p.

Research output: Contribution to journal › Article › peer-review

Structure of murine angiogenin: features of the substrate- and cell-binding regions and prospects for inhibitor-binding studies

Holloway, D. E., Chavali, G. B., Hares, M. C., Subramanian, V. & Acharya, K. R., 2005, In: Acta Crystallographica Section D-Biological Crystallography. 61, p. 1568-1578 11 p.

Research output: Contribution to journal › Article › peer-review

18 Citations (SciVal)

2001

Differential potential of intestinal mesenchyme and its interaction with epithelial cells: a study using beta-galactosidase-expressing fibroblast lines

Subramanian, V., Sneddon, S. F., Martin, L. & Evans, G. S., Aug 2001, In: Cell Biology International. 25, p. 741--751 11 p.

Research output: Contribution to journal › Article › peer-review

2 Citations (SciVal)

High-level expression of three members of the murine angiogenin family in Escherichia coli and purification of the recombinant proteins

Holloway, D. E., Hares, M. C., Shapiro, R., Subramanian, V. & Acharya, K. R., 2001, In: Protein Expression and Purification. 22, 2, p. 307-317 11 p.

Research output: Contribution to journal › Article › peer-review

41 Citations (SciVal)

Truncation of the MLL gene in exon 5 by gene targeting leads to early preimplantation lethality of homozygous embryos

Ayton, P., Sneddon, S. F., Palmer, D. B., Rosewell, I. R., Owen, M. J., Young, B., Presley, R. & Subramanian, V., Aug 2001, In: Genesis. 30, p. 201--212 12 p.

Research output: Contribution to journal › Article › peer-review

65 Citations (SciVal)

1998

The murine Cdx1 gene product localises to the proliferative compartment in the developing and regenerating intestinal epithelium

Subramanian, V., Meyer, B. & Evans, G. S., 1 Jan 1998, In: Differentiation. 64, 1, p. 11-18 8 p.

Research output: Contribution to journal › Article › peer-review

80 Citations (SciVal)

1995

Atlas of the Developing Rat Nervous System, 2nd ed., by George Paxinos, Ken W. S. Ashwell, and Istvan Törk. Academic Press, San Diego, 1994, ISBN 0‐12‐547610‐8 (paper), $125.00.

Subramanian, V., 1 Jan 1995, In: Journal of Neurochemistry. 65, 1, p. 471 1 p.

Research output: Contribution to journal › Article › peer-review

Disruption of the murine homeobox gene Cdx1 affects axial skeletal identities by altering the mesodermal expression domains of Hox genes

Subramanian, V., Meyer, B. I. & Gruss, P., 17 Nov 1995, In: Cell. 83, 4, p. 641-653 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

The Mouse Angiogenin Gene Family: Structures of an Angiogenin-Related Protein Gene and Two Pseudogenes

Brown, W. E., Nobile, V., Subramanian, V. & Shapiro, R., 1 Sept 1995, In: Genomics. 29, 1, p. 200-206 7 p.

Research output: Contribution to journal › Article › peer-review

The Rat Nervous System, 2nd ed., edited by George Paxinos. Academic Press, San Diego, 1994, ISBN 0‐12‐54763‐3 (case), 1,136 pp., $169.00.

Subramanian, V., 1 Jan 1995, In: Journal of Neurochemistry. 65, 1, p. 471 1 p.

Research output: Contribution to journal › Article › peer-review

1992

Crystallization and preliminary X-ray analysis of human angiogenin

Acharya, K. R., Subramanian, V., Shapiro, R., Riordan, J. F. & Vallee, B. L., 20 Dec 1992, In: Journal of Molecular Biology. 228, 4, p. 1269-1270 2 p.

Research output: Contribution to journal › Article › peer-review

1989

A malignant, stem cell-like somatic hybrid between a mouse teratocarcinoma and a rat ascitic hepatoma is differentiation competent

Subramanian, V., 1 Sept 1989, In: Cell Differentiation and Development. 27, 3, p. 197-214 18 p.

Research output: Contribution to journal › Article › peer-review

Vasanta Subramanian

Research output

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