• 4 SOUTH 0.67

Accepting PhD Students

1989 …2021
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Research Output 1989 2018

2018

A comparative bioinformatic analysis of C9orf72

Iyer, S., Acharya, K. R. & Subramanian, V., 19 Feb 2018, In : PeerJ. 6, p. e4391

Research output: Contribution to journalArticle

Open Access
Neurodegenerative diseases
Bioinformatics
Computational Biology
bioinformatics
Introns

C9orf72, a protein associated with amyotrophic lateral sclerosis (ALS) is a guanine nucleotide exchange factor

Iyer, S., Subramanian, V. & Acharya, K. R., 17 Oct 2018, In : PeerJ. 6, 29 p., e5815.

Research output: Contribution to journalArticle

Open Access

Embryoid body arrays: Parallel cryosectioning of spheroid/embryoid body samples for medium through-put analysis

Ferguson, R. & Subramanian, V., 1 Apr 2018, In : Stem Cell Research. 28, p. 125-130 6 p.

Research output: Contribution to journalArticle

Open Access
Cryoultramicrotomy
Embryoid Bodies
Organoids
Histological Techniques
Organogenesis
Neprilysin
Neurotensin
Protein Conformation
Enkephalins
Metalloproteases
Amyotrophic Lateral Sclerosis
Mutation
Proteins
Motor Neuron Disease
Missense Mutation

The cellular uptake of angiogenin, an angiogenic and neurotrophic factor is through multiple pathways and largely dynamin independent

Ferguson, R. & Subramanian, V., 27 Feb 2018, In : PLoS ONE. 13, 2, p. e0193302

Research output: Contribution to journalArticle

Open Access
Dynamins
neurotrophins
Angiogenesis Inducing Agents
Nerve Growth Factors
uptake mechanisms
2017
2 Citations

Structural insights into human angiogenin variants implicated in Parkinson's disease and Amyotrophic Lateral Sclerosis

Bradshaw, W. J., Rehman, S., Pham, T. T. K., Thiyagarajan, N., Lee, R. L., Subramanian, V. & Acharya, K. R., 8 Feb 2017, In : Scientific Reports. 7, 41996.

Research output: Contribution to journalArticle

Open Access
Amyotrophic Lateral Sclerosis
Parkinson Disease
Cell Line
Pancreatic Ribonuclease
Ribonucleases
2016
2 Citations
Open Access
File
Motor Neuron Disease
neurodevelopment
sclerosis
nervous system
Central Nervous System
2 Citations

PA6 Stromal Cell Co-Culture Enhances SH-SY5Y and VSC4.1 Neuroblastoma Differentiation to Mature Phenotypes

Ferguson, R. & Subramanian, V., 8 Jul 2016, In : PLoS ONE. 11, 7, e0159051.

Research output: Contribution to journalArticle

Open Access
File
stromal cells
coculture
Stromal Cells
Coculture Techniques
Neuroblastoma
2015

An investigation into the roles of Talpid3 and primary cilia in the developing brain

Bashford, A., May 2015, (Unpublished) 293 p.

Research output: ThesisDoctoral Thesis

File
Cilia
Brain
Hedgehogs
Phenotype
Centrioles
2012
37 Citations

Structural and molecular insights into the mechanism of action of human angiogenin-ALS variants in neurons.

Thiyagarajan, N., Ferguson, R., Subramanian, V. & Acharya, K. R., 9 Oct 2012, In : Nature Communications. 3, 14 p., 1121.

Research output: Contribution to journalArticle

Advanced Launch System (STS)
neurons
Neurons
cultured cells
Parkinson disease
14 Citations

Ribonuclease A homologues of the zebrafish: polymorphism, crystal structures of two representatives and their evolutionary implications

Kazakou, K., Holloway, D. E., Prior, S. H., Subramanian, V. & Acharya, K. R., 27 Jun 2008, In : Journal of Molecular Biology. 380, 1, p. 206-222 17 p.

Research output: Contribution to journalArticle

Pancreatic Ribonuclease
Zebrafish
Ribonucleases
Vertebrates
Catalytic Domain
2007
54 Citations

A new role for angiogenin in neurite growth and pathfinding: implications for amyotrophic lateral sclerosis

Subramanian, V. & Feng, Y., Jun 2007, In : Human Molecular Genetics. 16, p. 1445--1453 9 p.

Research output: Contribution to journalArticle

24 Citations

Biological and structural features of murine angiogenin-4, an angiogenic protein

Crabtree, B., Holloway, D. E., Baker, M. D., Acharya, K. R. & Subramanian, V., 2007, In : Biochemistry. 46, 9, p. 2431-2443 13 p.

Research output: Contribution to journalArticle

66 Citations

Characterization of human angiogenin variants implicated in amyotrophic lateral sclerosis

Crabtree, B., Thiyagarajan, N., Prior, S. H., Wilson, P., Iyer, S., Ferns, T., Shapiro, R., Brew, K., Subramanian, V. & Acharya, K. R., 2007, In : Biochemistry. 46, 42, p. 11810-11818 9 p.

Research output: Contribution to journalArticle

2005

Investigating the potential functions of murine Angiogenin 4

Crabtree, B., Acharya, K. R. & Subramanian, V., 2005, In : Genetics Research. 86, 3, p. 234-234 1 p.

Research output: Contribution to journalArticle

14 Citations
2001
2 Citations

Differential potential of intestinal mesenchyme and its interaction with epithelial cells: a study using beta-galactosidase-expressing fibroblast lines

Subramanian, V., Sneddon, S. F., Martin, L. & Evans, G. S., Aug 2001, In : Cell Biology International. 25, p. 741--751 11 p.

Research output: Contribution to journalArticle

31 Citations

High-level expression of three members of the murine angiogenin family in Escherichia coli and purification of the recombinant proteins

Holloway, D. E., Hares, M. C., Shapiro, R., Subramanian, V. & Acharya, K. R., 2001, In : Protein Expression and Purification. 22, 2, p. 307-317 11 p.

Research output: Contribution to journalArticle

55 Citations

Truncation of the MLL gene in exon 5 by gene targeting leads to early preimplantation lethality of homozygous embryos

Ayton, P., Sneddon, S. F., Palmer, D. B., Rosewell, I. R., Owen, M. J., Young, B., Presley, R. & Subramanian, V., Aug 2001, In : Genesis. 30, p. 201--212 12 p.

Research output: Contribution to journalArticle

1999
53 Citations

The angiogenins: An emerging family of ribonuclease related proteins with diverse cellular functions

Adams, S. A. & Subramanian, V., Sep 1999, In : Angiogenesis. 3, 3, p. 189-199 11 p.

Research output: Contribution to journalReview article

1998
75 Citations

The murine Cdx1 gene product localises to the proliferative compartment in the developing and regenerating intestinal epithelium

Subramanian, V., Meyer, B. & Evans, G. S., 1 Jan 1998, In : Differentiation. 64, 1, p. 11-18 8 p.

Research output: Contribution to journalArticle

Disruption of the murine homeobox gene Cdx1 affects axial skeletal identities by altering the mesodermal expression domains of Hox genes

Subramanian, V., Meyer, B. I. & Gruss, P., 17 Nov 1995, In : Cell. 83, 4, p. 641-653 13 p.

Research output: Contribution to journalArticle

Open Access

The Mouse Angiogenin Gene Family: Structures of an Angiogenin-Related Protein Gene and Two Pseudogenes

Brown, W. E., Nobile, V., Subramanian, V. & Shapiro, R., 1 Sep 1995, In : Genomics. 29, 1, p. 200-206 7 p.

Research output: Contribution to journalArticle

1992

Crystallization and preliminary X-ray analysis of human angiogenin

Acharya, K. R., Subramanian, V., Shapiro, R., Riordan, J. F. & Vallee, B. L., 20 Dec 1992, In : Journal of Molecular Biology. 228, 4, p. 1269-1270 2 p.

Research output: Contribution to journalArticle