Research output per year
Research output per year
- 29 results
Search results
-
2024
Synergistic Interface Platforms: Designing Superhydrophilic Conductive Nanoparticle-Decorated Nanofibrous Membranes
Keirouz, A., Jungwirth, U., Graf, A. & Leese, H. S., 6 Jun 2024, In: Advanced Materials Interfaces. 11, 16, 13 p., 2400040.Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (SciVal) -
2023
3D-Printed Hollow Microneedle-Lateral Flow Devices for Rapid Blood-Free Detection of C-Reactive Protein and Procalcitonin
Turner, J., Lay, E., Jungwirth, U., Varenko, V., Gill, H. S., Estrela, P. & Leese, H., 25 Aug 2023, In: Advanced Materials Technologies. 8, 16, 11 p., 2300259.Research output: Contribution to journal › Article › peer-review
Open AccessFile21 Citations (SciVal)110 Downloads (Pure) -
Conductive polymer-coated 3D printed microneedles: biocompatible platforms for minimally invasive biosensing interfaces
Keirouz, A., Mustafa, Y., Turner, J., Lay, E., Jungwirth, U., Marken, F. & Leese, H., 5 Apr 2023, In: Small. 19, 14, 2206301.Research output: Contribution to journal › Article › peer-review
Open Access58 Citations (SciVal) -
Ectopic expression of HNF4α in Het1A cells induces an invasive phenotype
Grimaldos Rodriguez, C., Rimmer, E. F., Colleypriest, B., Tosh, D., Slack, J. M. W. & Jungwirth, U., 30 Nov 2023, In: Differentiation. 134, p. 1-10Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (SciVal)3 Downloads (Pure) -
2022
Cancer-Associated Fibroblasts Suppress CD8+ T-cell Infiltration and Confer Resistance to Immune-Checkpoint Blockade
Jenkins, L., Jungwirth, U., Avgustinova, A., Iravani, M., Mills, A., Haider, S., Harper, J. & Isacke, C. M., 16 Aug 2022, In: Cancer Research. 82, 16, p. 2904-2917 14 p.Research output: Contribution to journal › Article › peer-review
Open Access122 Citations (SciVal) -
Phenanthroindolizidine Alkaloids Isolated from Tylophora ovata as Potent Inhibitors of Inflammation, Spheroid Growth, and Invasion of Triple-Negative Breast Cancer
Reimche, I., Yu, H., Ariantari, N. P., Liu, Z., Merkens, K., Rotfuß, S., Peter, K., Jungwirth, U., Bauer, N., Kiefer, F., Neudörfl, J. M., Schmalz, H. G., Proksch, P. & Teusch, N., 7 Sept 2022, In: International Journal of Molecular Sciences. 23, 18, 10319.Research output: Contribution to journal › Article › peer-review
Open Access9 Citations (SciVal) -
2021
Impairment of a distinct cancer-associated fibroblast population limits tumour growth and metastasis
Jungwirth, U., van Weverwijk, A., Evans, R. J., Jenkins, L., Vicente, D., Alexander, J., Gao, Q., Haider, S., Iravani, M. & Isacke, C. M., 10 Jun 2021, In: Nature Communications. 12, 1, 17 p., 3516.Research output: Contribution to journal › Article › peer-review
Open Access37 Citations (SciVal) -
2020
Impairment of a distinct cancer-associated fibroblast population limits tumour growth and metastasis
Jungwirth, U., van Weverwijk, A., Jenkins, L., Alexander, J., Vicente, D., Gao, Q., Haider, S., Iravani, M. & Isacke, C. M., 17 May 2020, (Submitted) In: bioRxiv.Research output: Contribution to journal › Article
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2019
Metabolic adaptability in metastatic breast cancer by AKR1B10-dependent balancing of glycolysis and fatty acid oxidation
van Weverwijk, A., Koundouros, N., Iravani, M., Ashenden, M., Gao, Q., Poulogiannis, G., Jungwirth, U. & Isacke, C. M., 20 Jun 2019, In: Nature Communications. 10, 1, 2698.Research output: Contribution to journal › Article › peer-review
Open Access81 Citations (SciVal) -
Preclinical studies on metal based anticancer drugs as enabled by integrated metallomics and metabolomics
Galvez, L., Rusz, M., Schwaiger-Haber, M., El Abiead, Y., Hermann, G., Jungwirth, U., Berger, W., Keppler, B. K., Jakupec, M. A. & Koellensperger, G., 1 Oct 2019, In: Metallomics. 11, 10, p. 1716-1728 13 p.Research output: Contribution to journal › Article › peer-review
Open Access25 Citations (SciVal) -
2018
Generation and characterisation of two D2A1 mammary cancer sublines to model spontaneous and experimental metastasis in a syngeneic BALB/c host
Jungwirth, U., van Weverwijk, A., Melake, M. J., Chambers, A. F., Gao, Q., Fivaz, M. & Isacke, C. M., 18 Jan 2018, In: Disease Models and Mechanisms. 11, 1, dmm031740.Research output: Contribution to journal › Article › peer-review
Open Access12 Citations (SciVal) -
2017
Comparative studies of oxaliplatin-based platinum(iv) complexes in different in vitro and in vivo tumor models
Göschl, S., Schreiber-Brynzak, E., Pichler, V., Cseh, K., Heffeter, P., Jungwirth, U., Jakupec, M. A., Berger, W. & Keppler, B. K., 22 Mar 2017, In: Metallomics. 9, 3, p. 309-322 14 p.Research output: Contribution to journal › Article › peer-review
Open Access58 Citations (SciVal) -
2014
Calpain-mediated integrin deregulation as a novel mode of action for the anticancer gallium compound KP46
Jungwirth, U., Gojo, J., Tuder, T., Walko, G., Holcmann, M., Schöfl, T., Nowikovsky, K., Wilfinger, N., Schoonhoven, S., Kowol, C. R., Lemmens-Gruber, R., Heffeter, P., Keppler, B. K. & Berger, W., Oct 2014, In: Molecular Cancer Therapeutics. 13, 10, p. 2436-49 14 p.Research output: Contribution to journal › Article › peer-review
23 Citations (SciVal) -
Enhanced anticancer activity and circumvention of resistance mechanisms by novel polymeric/phospholipidic nanocarriers of doxorubicin
Senkiv, Y., Riabtseva, A., Heffeter, P., Boiko, N., Kowol, C. R., Jungwith, U., Shlyakhtina, Y., Garasevych, S. G., Mitina, N., Berger, W., Zaichenko, A. & Stoika, R., 31 Jul 2014, In: Journal of Biomedical Nanotechnology. 10, 7, p. 1369-1381 13 p.Research output: Contribution to journal › Article › peer-review
19 Citations (SciVal) -
Nanoformulation improves activity of the (pre)clinical anticancer ruthenium complex KP1019
Heffeter, P., Riabtseva, A., Senkiv, Y., Kowol, C. R., Körner, W., Jungwith, U., Mitina, N., Keppler, B. K., Konstantinova, T., Yanchuk, I., Stoika, R., Zaichenko, A. & Berger, W., 31 May 2014, In: Journal of Biomedical Nanotechnology. 10, 5, p. 877-884 8 p.Research output: Contribution to journal › Article › peer-review
32 Citations (SciVal) -
Triapine and a more potent dimethyl derivative induce endoplasmic reticulum stress in cancer cells
Trondl, R., Flocke, L. S., Kowol, C. R., Heffeter, P., Jungwirth, U., Mair, G. E., Steinborn, R., Enyedy, É. A., Jakupec, M. A., Berger, W. & Keppler, B. K., Mar 2014, In: Molecular Pharmacology. 85, 3, p. 451-9 9 p.Research output: Contribution to journal › Article › peer-review
38 Citations (SciVal) -
2013
Influence of extracellular pH on the cytotoxicity, cellular accumulation, and DNA interaction of novel pH-sensitive 2-aminoalcoholatoplatinum(II) complexes
Valiahdi, S. M., Egger, A. E., Miklos, W., Jungwirth, U., Meelich, K., Nock, P., Berger, W., Hartinger, C. G., Galanski, M., Jakupec, M. A. & Keppler, B. K., Feb 2013, In: Journal of Biological Inorganic Chemistry. 18, 2, p. 249-60 12 p.Research output: Contribution to journal › Article › peer-review
16 Citations (SciVal) -
Organometallic anticancer complexes of lapachol: metal centre-dependent formation of reactive oxygen species and correlation with cytotoxicity
Kandioller, W., Balsano, E., Meier, S. M., Jungwirth, U., Göschl, S., Roller, A., Jakupec, M. A., Berger, W., Keppler, B. K. & Hartinger, C. G., 25 Apr 2013, In: Chemical communications (Cambridge, England). 49, 32, p. 3348-50 3 p.Research output: Contribution to journal › Article › peer-review
Open Access132 Citations (SciVal) -
Synergistic anticancer activity of arsenic trioxide with erlotinib is based on inhibition of EGFR-mediated DNA double-strand break repair
Kryeziu, K., Jungwirth, U., Hoda, M. A., Ferk, F., Knasmüller, S., Karnthaler-Benbakka, C., Kowol, C. R., Berger, W. & Heffeter, P., Jun 2013, In: Molecular Cancer Therapeutics. 12, 6, p. 1073-84 12 p.Research output: Contribution to journal › Article › peer-review
49 Citations (SciVal) -
The ruthenium compound KP1339 potentiates the anticancer activity of sorafenib in vitro and in vivo
Heffeter, P., Atil, B., Kryeziu, K., Groza, D., Koellensperger, G., Körner, W., Jungwirth, U., Mohr, T., Keppler, B. K. & Berger, W., Oct 2013, In: European Journal of Cancer. 49, 15, p. 3366-75 10 p.Research output: Contribution to journal › Article › peer-review
Open Access78 Citations (SciVal) -
2012
Anticancer activity of methyl-substituted oxaliplatin analogs
Jungwirth, U., Xanthos, D. N., Gojo, J., Bytzek, A. K., Körner, W., Heffeter, P., Abramkin, S. A., Jakupec, M. A., Hartinger, C. G., Windberger, U., Galanski, M., Keppler, B. K. & Berger, W., May 2012, In: Molecular Pharmacology. 81, 5, p. 719-28 10 p.Research output: Contribution to journal › Article › peer-review
63 Citations (SciVal) -
Impact of terminal dimethylation on the resistance profile of α-N-heterocyclic thiosemicarbazones
Heffeter, P., Pirker, C., Kowol, C. R., Herrman, G., Dornetshuber, R., Miklos, W., Jungwirth, U., Koellensperger, G., Keppler, B. K. & Berger, W., 15 Jun 2012, In: Biochemical Pharmacology. 83, 12, p. 1623-33 11 p.Research output: Contribution to journal › Article › peer-review
Open Access18 Citations (SciVal) -
Trivanillic polyphenols with anticancer cytostatic effects through the targeting of multiple kinases and intracellular Ca2+ release
Lamoral-Theys, D., Wauthoz, N., Heffeter, P., Mathieu, V., Jungwirth, U., Lefranc, F., Nève, J., Dubois, J., Dufrasne, F., Amighi, K., Berger, W., Gailly, P. & Kiss, R., Jul 2012, In: Journal of Cellular and Molecular Medicine. 16, 7, p. 1421-1434 14 p.Research output: Contribution to journal › Article › peer-review
Open Access13 Citations (SciVal) -
2011
Targeted proteolysis of plectin isoform 1a accounts for hemidesmosome dysfunction in mice mimicking the dominant skin blistering disease EBS-Ogna
Walko, G., Vukasinovic, N., Gross, K., Fischer, I., Sibitz, S., Fuchs, P., Reipert, S., Jungwirth, U., Berger, W., Salzer, U., Carugo, O., Castañón, M. J. & Wiche, G., Dec 2011, In: Plos Genetics. 7, 12, p. e1002396Research output: Contribution to journal › Article › peer-review
Open Access54 Citations (SciVal) -
2010
{(1R,2R,4R)-4-methyl-1,2-cyclohexanediamine}oxalatoplatinum(II): a novel enantiomerically pure oxaliplatin derivative showing improved anticancer activity in vivo
Abramkin, S. A., Jungwirth, U., Valiahdi, S. M., Dworak, C., Habala, L., Meelich, K., Berger, W., Jakupec, M. A., Hartinger, C. G., Nazarov, A. A., Galanski, M. & Keppler, B. K., 28 Oct 2010, In: Journal of Medicinal Chemistry. 53, 20, p. 7356-64 9 p.Research output: Contribution to journal › Article › peer-review
55 Citations (SciVal) -
Intracellular protein binding patterns of the anticancer ruthenium drugs KP1019 and KP1339
Heffeter, P., Böck, K., Atil, B., Reza Hoda, M. A., Körner, W., Bartel, C., Jungwirth, U., Keppler, B. K., Micksche, M., Berger, W. & Koellensperger, G., Jun 2010, In: Journal of Biological Inorganic Chemistry. 15, 5, p. 737-48 12 p.Research output: Contribution to journal › Article › peer-review
156 Citations (SciVal) -
2009
Ribonucleotide reductase as one important target of [Tris(1,10-phenanthroline)lanthanum(III)] trithiocyanate (KP772)
Heffeter, P., Popovic-Bijelic, A., Saiko, P., Dornetshuber, R., Jungwirth, U., Voevodskaya, N., Biglino, D., Jakupec, M. A., Elbling, L., Micksche, M., Szekeres, T., Keppler, B. K., Gräslund, A. & Berger, W., Aug 2009, In: Current Cancer Drug Targets. 9, 5, p. 595-607 13 p.Research output: Contribution to journal › Article › peer-review
24 Citations (SciVal) -
The Na+/K+-ATPase is the Achilles Heel of multi-drug-resistant cancer cells
Mijatovic, T., Jungwirth, U., Heffeter, P., Hoda, M. A. R., Dornetshuber, R., Kiss, R. & Berger, W., 8 Sept 2009, In: Cancer Letters. 282, 1, p. 30-34 5 p.Research output: Contribution to journal › Article › peer-review
39 Citations (SciVal) -
2008
Cisplatin and siRNA interference with structure and function of Wnt-5a mRNA: design and in vitro evaluation of targeting AU-rich elements in the 3' UTR
Hägerlöf, M., Papsai, P., Hedman, H. K., Jungwirth, U., Jenei, V. & Elmroth, S. K. C., Mar 2008, In: Journal of Biological Inorganic Chemistry. 13, 3, p. 385-99 15 p.Research output: Contribution to journal › Article › peer-review
11 Citations (SciVal)