Personal profile
Research interests
Our lab at the University of Bath is interested in the role of tumour microenvironment and how it impacts tumour progression and therapy response. We aim to identify novel strategies to target the tumour and/or stroma for the prevention or suppression of (metastatic) cancer and to overcome treatment-resistant tumour progression.
Biography
Until January 2024, I was Senior Lecturer (Associate Professor) at the University of Bath. Since then I am a Visiting Senior Research Fellow at the University of Bath and Senior Lecturer (Associate Professor) in Cancer Drug Discovery at Newcastle University in the Cancer Research UK Newcastle Drug Discovery Unit and Translational and Clinical Research Institute.
Current University of Bath lab members:
Ioanna Kontou (PhD student)
Tressan Grant (PhD student)
Ella Rimmer (PhD stduent together with Prof Tosh)
Pooja Murali (MBiochem student together with Dr Gurevich)
Former lab members:
PhD students:
Emily Lay (Oct 2019-Aug 2023)
Carmen Grimaldos Rodriguez (Nov 2018-Mar 2023, together with Prof Tosh)
MSc students:
Uliana Filie (MSc Molecular Biosciences 2023), Amalda Erdmane (MSc Molecular Biosciences 2023), Spyroula Antoniou (MSc Drug Discovery, 2021), Shujun Wang (MSc Drug Discovery, 2020)
BSc final year students:
Phoebe Elvin (BSc Biochem 2023/24), Victoria Summers (BSc Biochem, 2022/23), Sophie Bliss (BSc Biochem, 2022/23), Honor Tookey (BSc Biochem, 2022/23), Laura Edwards (BSc BiomedSci, 2021/22), Sabrina James (BSc BiomedSci, 2021/22), Mari Davies (BSc BiomedSci, 2019/20), Meryl Attrill (BSc BiomedSci, final 2019/20)
ERASMUS visiting students:
Simone Herwig (2022), Anna Lauridsen (2018/19)
Education/Academic qualification
Malignant Diseases, Doctor of Philosophy, Medical University of Vienna
Toxicology, Master of Science, Medical University of Vienna
Chemistry, Master of Chemistry, University of Vienna
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
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Multi User High-Content Confocal Microscope
Sero, J. (PI), Cevik, V. (CoI), Gurevich, D. (CoI), Jungwirth, U. (CoI), Kelsh, R. (CoI), Koumanov, F. (CoI), Kyprianou, A. (CoI), Laabei, M. (CoI), Licchesi, J. (CoI), Murrell, A. (CoI), Pascu, S. (CoI), Turner, L. (CoI), Walko, G. (CoI), Ward, A. (CoI), Ward, S. (CoI), Williams, R. (CoI) & Zachariadis, M. (CoI)
Biotechnology and Biological Sciences Research Council
1/08/22 → 31/07/23
Project: Research council
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How fibroblasts and azathioprine prepare the soil for cutaneous squamous cell carcinoma
Jungwirth, U. (PI)
1/07/22 → 30/06/25
Project: UK charity
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Collagen remodelling by stromal fibroblasts in breast cancer metastasis
Jungwirth, U. (CoI)
1/06/15 → 31/05/18
Project: Project at a former HEI
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Extracellular matrix remodelling in breast cancer metastasis
Jungwirth, U. (PI)
1/06/13 → 31/05/15
Project: Project at a former HEI
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Generation of 3D Fibroblast-Derived Extracellular Matrix and Analysis of Tumor Cell-Matrix Interactions and Signaling
Lay, E., Grant, T., Walko, G. & Jungwirth, U., 7 May 2024, Imaging Cell Signaling. Wuelfing, C. & Murphy, R. F. (eds.). 1st ed. New York, U. S. A.: Humana Press, Vol. 2800. p. 11-25 15 p. (Methods in Molecular Biology ; vol. 2800).Research output: Chapter or section in a book/report/conference proceeding › Book chapter
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Synergistic Interface Platforms: Designing Superhydrophilic Conductive Nanoparticle-Decorated Nanofibrous Membranes
Keirouz, A., Jungwirth, U., Graf, A. & Leese, H. S., 6 Jun 2024, In: Advanced Materials Interfaces. 11, 16, 13 p., 2400040.Research output: Contribution to journal › Article › peer-review
Open Access3 Link opens in a new tab Citations (SciVal) -
3D-Printed Hollow Microneedle-Lateral Flow Devices for Rapid Blood-Free Detection of C-Reactive Protein and Procalcitonin
Turner, J., Lay, E., Jungwirth, U., Varenko, V., Gill, H. S., Estrela, P. & Leese, H., 25 Aug 2023, In: Advanced Materials Technologies. 8, 16, 11 p., 2300259.Research output: Contribution to journal › Article › peer-review
Open AccessFile50 Link opens in a new tab Citations (SciVal)232 Downloads (Pure) -
Conductive polymer-coated 3D printed microneedles: biocompatible platforms for minimally invasive biosensing interfaces
Keirouz, A., Mustafa, Y., Turner, J., Lay, E., Jungwirth, U., Marken, F. & Leese, H., 5 Apr 2023, In: Small. 19, 14, 2206301.Research output: Contribution to journal › Article › peer-review
Open Access101 Link opens in a new tab Citations (SciVal) -
Ectopic expression of HNF4α in Het1A cells induces an invasive phenotype
Grimaldos Rodriguez, C., Rimmer, E. F., Colleypriest, B., Tosh, D., Slack, J. M. W. & Jungwirth, U., 30 Nov 2023, In: Differentiation. 134, p. 1-10Research output: Contribution to journal › Article › peer-review
Open Access2 Link opens in a new tab Citations (SciVal)3 Downloads (Pure)
Datasets
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Dataset for "Conductive polymer-coated 3D printed microneedles: biocompatible platforms for minimally invasive biosensing interfaces"
Keirouz, T. (Creator), Mustafa, Y. (Creator), Turner, J. (Creator), Lay, E. (Creator), Jungwirth, U. (Creator), Marken, F. (Creator) & Leese, H. (Creator), University of Bath, 3 Jan 2023
DOI: 10.15125/BATH-01210
Dataset
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Dataset for "3D‐Printed Hollow Microneedle‐Lateral Flow Devices for Rapid Blood‐Free Detection of C‐Reactive Protein and Procalcitonin"
Turner, J. (Creator), Lay, E. (Creator), Jungwirth, U. (Creator), Varenko, V. (Creator), Gill, R. (Creator), Estrela, P. (Creator) & Leese, H. (Creator), University of Bath, 28 Apr 2023
DOI: 10.15125/BATH-01233
Dataset