Tony James

Royal Society Wolfson Research Merit Award Holder, Fellow of the Royal Society of Chemistry, Prof

  • 1 SOUTH 0.21

Accepting PhD Students

1987 …2022
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Research Output 1987 2019

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Article
2019

A molecular design strategy to construct the near-infrared fluorescent probe for selectively sensing human cytochrome P450 2J2

Ning, J., Liu, T., Dong, P., Wang, W., Ge, G., Wang, B., Yu, Z., Shi, L., Tian, X., Huo, X., Feng, L., Wang, C., Sun, C., Cui, J-N., James, T. D. & Ma, X., 16 Jan 2019, In : Journal of the American Chemical Society. 141, 2, p. 1126-1134 9 p.

Research output: Contribution to journalArticle

ESIPT-based fluorescence probe for the ratiometric detection of superoxide

Wu, L., Liu, L., Han, H. H., Tian, X., Odyniec, M. L., Feng, L., Sedgwick, A. C., He, X. P., Bull, S. D. & James, T. D., 23 Jan 2019, In : New Journal of Chemistry. 43, 7, p. 2875-2877 3 p.

Research output: Contribution to journalArticle

Open Access

NAG-targeting fluorescence based probe for precision diagnosis of kidney injury

Yan, F., Tian, X., Luan, Z., Feng, L., Ma, X. & James, T. D., 7 Feb 2019, In : Chemical communications (Cambridge, England). 55, 13, p. 1955-1958 4 p.

Research output: Contribution to journalArticle

Open Access
2018
3 Citations (Scopus)

A fluorescent peptidyl substrate for visualizing peptidyl-prolyl cis/trans isomerase activity in live cells

Jiang, Q., Li, X-R., Wang, C-K., Cheng, J., Tan, C., Cui, T-T., Lu, N-N., James, T. D., Han, F. & Li, X., 21 Feb 2018, In : Chemical communications (Cambridge, England). 54, 15, p. 1857-1860 4 p.

Research output: Contribution to journalArticle

Open Access
File
Peptidylprolyl Isomerase
Imaging techniques
Communication
Substrates
Fluorescent Dyes
3 Citations (Scopus)

A hemicyanine based ratiometric fluorescence probe for mapping lysosomal pH during heat stroke in living cells

Wu, L., Wang, Y., James, T. D., Jia, N. & Huang, C., 11 Apr 2018, In : Chemical Communications. 54, p. 5518-5521 4 p.

Research output: Contribution to journalArticle

Open Access
Fluorescence
Cells
Fluorophores
Neurology
Fluorescent Dyes

A naphthoimidazolium-cholesterol derivative as a ratiometric fluorescence based chemosensor for the chiral recognition of carboxylates

Zhang, X., Ko, G., Joung, J. F., Li, M., Jeong, Y., Swamy, K. M. K., Lee, D., Liu, Y., Lee, S., Park, S., James, T. D. & Yoon, J., 22 Nov 2018, In : Chemical communications (Cambridge, England). 54, 94, p. 13264-13267 4 p.

Research output: Contribution to journalArticle

Open Access
1 Citations (Scopus)

'AND'-based fluorescence scaffold for the detection of ROS/RNS and a second analyte

Odyniec, M. L., Sedgwick, A. C., Swan, A. H., Weber, M., Tang, T. M. S., Gardiner, J. E., Zhang, M., Jiang, Y. B., Kociok-Kohn, G., Elmes, R. B. P., Bull, S. D., He, X. P. & James, T. D., 27 Jun 2018, In : Chemical Communications. 54, p. 8466-8469 4 p.

Research output: Contribution to journalArticle

Open Access
Scaffolds
Fluorescence
Biomarkers
Esterases
Fluorescent Dyes
1 Citations (Scopus)

An ESIPT Probe for the Ratiometric Imaging of Peroxynitrite Facilitated by Binding to Aβ-Aggregates

Sedgwick, A. C., Dou, W. T., Jiao, J. B., Wu, L., Williams, G. T., Jenkins, A. T. A., Bull, S. D., Sessler, J. L., He, X. P. & James, T. D., 31 Oct 2018, In : Journal of the American Chemical Society. 140, 43, p. 14267-14271 5 p.

Research output: Contribution to journalArticle

Open Access
10 Citations (Scopus)

A quick and selective rhodamine based “smart probe” for “signal-on” optical detection of Cu2+ and Al3+ in water, cell imaging, computational studies and solid state analysis

Rai, A., Singh, A. K., Tripathi, K., Sonkar, A. K., Chauhan, B. S., Srikrishna, S., James, T. D. & Mishra, L., 1 Aug 2018, In : Sensors and Actuators B: Chemical. 266, p. 95-105

Research output: Contribution to journalArticle

Rhodamines
rhodamine
solid state
Imaging techniques
Water
7 Citations (Scopus)
Open Access
File
Fructose
Bolts
Boronic Acids
Acids
Fluorescence
1 Citations (Scopus)

A simple umbelliferone based fluorescent probe for the detection of nitroreductase

Sedgwick, A. C., Hayden, A., Hill, B., Bull, S. D., Elmes, R. B. P. & James, T. D., 1 Jun 2018, In : Frontiers of Chemical Science and Engineering. 12, 2, p. 311-314 4 p.

Research output: Contribution to journalArticle

Open Access
File
7-hydroxycoumarin
Nitroreductases
Fluorescent Dyes
Enzymes
Fluorophores
2 Citations (Scopus)

Biodegradable macroporous scaffold with nano-crystal surface microstructure for highly effective osteogenesis and vascularization

Chu, L., Jiang, G., Hu, X., James, T. D., He, X-P., Li, Y. & Tang, T., 21 Mar 2018, In : Journal of Materials Chemistry B . 6, 11, p. 1658-1667

Research output: Contribution to journalArticle

Open Access
File
Scaffolds
Scaffolds (biology)
Crystals
Microstructure
Calcium
4 Citations (Scopus)

Boronate-Based Fluorescence Probes for the Detection of Hydrogen Peroxide

Lampard, E. V., Sedgwick, A. C., Sun, X., Filer, K. L., Hewins, S. C., Kim, G., Yoon, J., Bull, S. D. & James, T. D., 1 Mar 2018, In : ChemistryOpen. 7, 3, p. 262-265

Research output: Contribution to journalArticle

Open Access

Correction: Boronate based fluorescence (ESIPT) probe for peroxynitrite(Chem. Commun. (2016) 52 (12350–12352) DOI: 10.1039/C6CC06829D)

Sedgwick, A. C., Sun, X., Kim, G., Yoon, J., Bull, S. D. & James, T. D., 28 Sep 2018, In : Chemical Communications. 54, 76, p. 10775 1 p.

Research output: Contribution to journalArticle

Open Access

Correction: A bodipy based hydroxylamine sensor (Chemical Communications (2017) 53 (10441-10443) DOI: 10.1039/C7CC05872A)

Sedgwick, A. C., Chapman, R. S. L., Gardiner, J. E., Peacock, L. R., Kim, G., Yoon, J., Bull, S. D. & James, T. D., 4 Oct 2018, In : Chemical Communications. 54, 77, p. 10922 1 p.

Research output: Contribution to journalArticle

Open Access
5 Citations (Scopus)

Dual-function cellulose composites for fluorescence detection and removal of fluoride

Li, M., Liu, Z., Wang, H. C., Sedgwick, A. C., Gardiner, J. E., Bull, S. D., Xiao, H. N. & James, T. D., 1 Feb 2018, In : Dyes and Pigments. 149, p. 669-675 7 p.

Research output: Contribution to journalArticle

Open Access
File
Fluorides
Cellulose
Fluorescence
Adsorption
Composite materials

Dye Displacement Assay for Saccharides using Benzoxaborole Hydrogels

Lampard, E. V., Sedgwick, A. C., Sombuttan, T., Williams, G. T., Wannalerse, B., Jenkins, A. T. A., Bull, S. D. & James, T. D., 1 Mar 2018, In : ChemistryOpen. 7, 3, p. 266-268

Research output: Contribution to journalArticle

Open Access
Hydrogels
Assays
Coloring Agents
Boronic Acids
Monosaccharides
4 Citations (Scopus)

ESIPT-based fluorescence probe for the rapid detection of hypochlorite (HOCl/ClO-)

Wu, L., Yang, Q., Liu, L., Sedgwick, A. C., Cresswell, A. J., Bull, S. D., Huang, C. & James, T. D., 4 Jul 2018, In : Chemical Communications. 54, 61, p. 8522-8525 4 p.

Research output: Contribution to journalArticle

Open Access
Hypochlorous Acid
Fluorescence
Water
Logic gates
Potable water
1 Citations (Scopus)

ESIPT-based fluorescence probe for the rapid detection of peroxynitrite ‘AND' biological thiols

Wu, L., Han, H. H., Liu, L., Gardiner, J. E., Sedgwick, A. C., Huang, C., Bull, S. D., He, X. P. & James, T. D., 14 Oct 2018, In : Chemical Communications. 54, 80, p. 11336-11339 4 p.

Research output: Contribution to journalArticle

Open Access
5 Citations (Scopus)

ESIPT-based ratiometric fluorescence probe for the intracellular imaging of peroxynitrite

Wu, L., Wang, Y., Weber, M., Liu, L., Sedgwick, A. C., Bull, S. D., Huang, C. & James, T. D., 7 Aug 2018, In : Chemical Communications. 54, 71, p. 9953-9956 4 p.

Research output: Contribution to journalArticle

Open Access
Peroxynitrous Acid
Fluorescent Dyes
Fluorescence
Imaging techniques
Experiments

Fluorescence based Tool to Detect Endogenous Peroxynitrite in M1-Polarized Murine J774.2 Macrophages

Weber, M., Mackenzie, A. B., Bull, S. D. & James, T. D., 4 Sep 2018, In : Analytical Chemistry. 90, 17, p. 10621–10627 7 p.

Research output: Contribution to journalArticle

Open Access
File
Peroxynitrous Acid
Macrophages
Reactive Oxygen Species
Fluorescence
Oxidative stress
7 Citations (Scopus)

Fluorescence detection and removal of copper from water using a biobased and biodegradable 2D soft material

Li, M., Liu, Z., Wang, S., Calatayud, D. G., Zhu, W. H., James, T. D., Wang, L., Mao, B. & Xiao, H. N., 7 Jan 2018, In : Chemical Communications. 54, 2, p. 184-187 4 p.

Research output: Contribution to journalArticle

Open Access
Metal ions
Copper
Fluorescence
Graphite
Water
6 Citations (Scopus)

Long-wavelength TCF-based fluorescence probes for the detection and intracellular imaging of biological thiols

Sedgwick, A. C., Gardiner, J. E., Kim, G., Yevglevskis, M., Lloyd, M. D., Jenkins, A. T. A., Bull, S. D., Yoon, J. & James, T. D., 2018, In : Chemical Communications. 54, 38, p. 4786-4789 4 p.

Research output: Contribution to journalArticle

Open Access
Sulfhydryl Compounds
Toxicity
Fluorescence
Drug therapy
Imaging techniques

Osteogenesis, vascularization and osseointegration of a bioactive multiphase macroporous scaffold in the treatment of large bone defects

Chu, L., Jiang, G., Hu, X., James, T. D., He, X-P., Li, Y. & Tang, T., 2018, In : Journal of Materials Chemistry B . 6, 25, p. 4197-4204 10 p.

Research output: Contribution to journalArticle

Scaffolds
Bone
Defects
Bone Substitutes
Biocompatible Materials

Preferential colonization of osteoblasts over co-cultured bacteria on a bifunctional biomaterial surface

Chu, L., Yang, Y., Yang, S., Fan, Q., Yu, Z., Hu, X. L., James, T. D., He, X. P. & Tang, T., 2 Oct 2018, In : Frontiers in Microbiology. 9, OCT, 2219.

Research output: Contribution to journalArticle

Open Access

Proline-Based Boronic Acid Receptors for Chiral Recognition of Glucose

Guo, L-E., Hong, Y., Zhang, S-Y., Zhang, M., Yan, X-S., Cao, J-L., Li, Z., James, T. D. & Jiang, Y-B., 22 Nov 2018, In : Journal of Organic Chemistry. 8 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Promoting magnesium sulfite oxidation: Via partly oxidized metal nanoparticles on graphitic carbon nitride (g-C3N4) in the magnesia desulfurization process

Li, M., Qi, T., Yang, R., Xiao, H. N., Fang, Z., Hodge, S. A., James, T. D., Wang, L. & Mao, B., 28 Jun 2018, In : Journal of Materials Chemistry A. 6, 24, p. 11296-11305 10 p.

Research output: Contribution to journalArticle

Magnesium Oxide
Sulfites
Carbon nitride
Metal nanoparticles
Magnesia

Selective Cu2+ Ion Sensing by Nanoaggregates of Pyridyl-2,6-bis(3-allylsalicylaldehyde)hydrazone

Rai, A., Tripathi, K., Kumar Sonkar, A., James, T. D., Yashaswee, S., Kumar Trigun, S. & Mishra, L., 24 May 2018, In : ChemistrySelect. 3, 19, p. 5395-5400 6 p.

Research output: Contribution to journalArticle

Hydrazones
Ions
Cells
Water

Structure-activity relationships of rationally designed AMACR 1A inhibitors

Jevglevskis, M., Lee, G. L., Nathubhai, A., Petrova, Y., James, T., Threadgill, M., Woodman, T. & Lloyd, M., 1 Sep 2018, In : Bioorganic and Medicinal Chemistry. 79, p. 145-154 10 p.

Research output: Contribution to journalArticle

Acyl Coenzyme A
Enzyme activity
Coenzyme A
Assays
Esters

Supramolecular glyco-poly-cyclodextrin functionalized 2D probe for targeted stimulus-responsive bioimaging

Wang, H., Liu, Y., Xu, C., Wang, X., Chen, G-R., James, T. D., Zang, Y., Li, J., Ma, X. & He, X-P., 18 Apr 2018, In : Chemical Communications. 54, 32, p. 4037-4040

Research output: Contribution to journalArticle

Open Access
File
Cyclodextrins
Cells
14 Citations (Scopus)

The development of a novel AND logic based fluorescence probe for the detection of peroxynitrite and GSH

Sedgwick, A. C., Han, H. H., Gardiner, J. E., Bull, S. D., He, X-P. & James, T. D., 21 Apr 2018, In : Chemical Science. 9, 15, p. 3672-3676 5 p.

Research output: Contribution to journalArticle

Open Access
Peroxynitrous Acid
Fluorescence
Fluorescein
Imaging techniques
Experiments
2017
4 Citations (Scopus)

A 1-hydroxy-2,3,1-benzodiazaborine-containing π-conjugated system: synthesis, optical properties and solvent-dependent response toward anions

Satta, Y., Nishiyabu, R., James, T. D. & Kubo, Y., 13 Apr 2017, In : Tetrahedron. 73, 15, p. 2053-2061 9 p.

Research output: Contribution to journalArticle

File
Optical Devices
Dimethyl Sulfoxide
Anions
Boron
Optical properties
9 Citations (Scopus)

A bodipy based hydroxylamine sensor

Sedgwick, A. C., Chapman, R. S. L., Gardiner, J. E., Peacock, L. R., Kim, G., Yoon, J., Bull, S. D. & James, T. D., 25 Sep 2017, In : Chemical Communications. 53, 75, p. 10441-10443

Research output: Contribution to journalArticle

Open Access
Hydroxylamine
Fluorescence
Sensors
11 Citations (Scopus)

A fluorogenic 2D glycosheet for the simultaneous identification of human-and avian-receptor specificity in influenza viruses

Song, J. X., Tang, X. Y., Zhou, D. M., Zhang, W., James, T. D., He, X-P. & Tian, H., 1 May 2017, In : Materials Horizons. 4, 3, p. 431-436 6 p.

Research output: Contribution to journalArticle

Open Access
Viruses
Polysaccharides
Color
Fluorophores
Switches
3 Citations (Scopus)

A glutamic acid-modified cellulose fibrous composite used for the adsorption of heavy metal ions from single and binary solutions

Li, M., Liu, Z., Wang, L., James, T. D., Xiao, H. N. & Zhu, W. H., 1 Nov 2017, In : Materials Chemistry Frontiers. 1, 11, p. 2317-2323 7 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

A novel colorimetric assay for α-methylacyl-CoA racemase 1A (AMACR; P504S) utilizing the elimination of 2,4-dinitrophenolate

Jevglevskis, M., Lee, G. L., Nathubhai, A., Petrova, Y., James, T., Threadgill, M., Woodman, T. & Lloyd, M., 7 May 2017, In : Chemical Communications. 53, 37, p. 5087-5090 4 p.

Research output: Contribution to journalArticle

Open Access
Assays
Ibuprofen
Fatty acids
Fatty Acids
Degradation
16 Citations (Scopus)

Azulene–boronate esters: colorimetric indicators for fluoride in drinking water

Lopez-Alled, C. M., Sanchez Fernandez, A., Edler, K., Sedgwick, A., Bull, S., McMullin, C., Kociok-Kohn, G., James, T., Wenk, J. & Lewis, S., 4 Dec 2017, In : Chemical Communications. 53, 93, p. 12580-12583 4 p.

Research output: Contribution to journalArticle

Open Access
Fluorides
Developing countries
Potable water
Drinking Water
Esters
5 Citations (Scopus)

Behavior of Supramolecular Assemblies of Radiometal-Filled and Fluorescent Carbon Nanocapsules In Vitro and In Vivo

Ge, H., Riss, P. J., Mirabello, V., Calatayud, D. G., Flower, S. E., Arrowsmith, R. L., Fryer, T. D., Hong, Y., Sawiak, S., Jacobs, R. M. J., Botchway, S. W., Tyrrell, R. M., James, T. D., Fossey, J. S., Dilworth, J. R., Aigbirhio, F. I. & Pascu, S. I., 14 Sep 2017, In : Chem. 3, 3, p. 437-460 24 p.

Research output: Contribution to journalArticle

Open Access
Nanocapsules
Carbon Nanotubes
beta-Glucans
Carbon
Optical Imaging
8 Citations (Scopus)

Boronic Acid Mediated Coupling of Catechols and N-Hydroxylamines: A Bioorthogonal Reaction to Label Peptides

Meadows, M. K., Roesner, E. K., Lynch, V. M., James, T. D. & Anslyn, E. V., 16 Jun 2017, In : Organic Letters. 19, 12, p. 3179-3182 4 p.

Research output: Contribution to journalArticle

Open Access
File
Hydroxylamines
Catechols
Boronic Acids
peptides
Labels
1 Citations (Scopus)

Electroanalysis in 2D-TiO2 Nanosheet Hosts: Electrolyte and Selectivity Effects in Ferroceneboronic Acid – Saccharide Binding

Tri Wahyuni, W., Marken, F., Putra, B. R., Bavykin, D. V., Walsh, F. C., James, T., Kociok-Kohn, G. & Harito, C., 17 Nov 2017, In : Electroanalysis.

Research output: Contribution to journalArticle

Open Access
File
Nanosheets
Electrolytes
Fructose
Acids
Glucose
24 Citations (Scopus)

Fluorescent glycoprobes: a sweet addition for improved sensing

He, X. P., Zang, Y., James, T. D., Li, J., Chen, G. R. & Xie, J., 4 Jan 2017, In : Chemical Communications. 53, 1, p. 82-90 9 p.

Research output: Contribution to journalArticle

Open Access
Fluorescent Dyes
Solubility
Ions
Imaging techniques
Water
3 Citations (Scopus)

Graphene oxide-enhanced cytoskeleton imaging and mitosis tracking

Li, Q. R., Jiao, J. B., Li, L. L., He, X. P., Zang, Y., James, T. D., Chen, G. R., Guo, L. & Li, J., 28 Feb 2017, In : Chemical Communications. 53, 23, p. 3373-3376 4 p.

Research output: Contribution to journalArticle

Open Access
Graphite
Oxides
Graphene
Peptides
Imaging techniques
5 Citations (Scopus)

High-Throughput Assay for Enantiomeric Excess Determination in 1,2- and 1,3-Diols and Direct Asymmetric Reaction Screening

Shcherbakova, E. G., Brega, V., Lynch, V. M., James, T. D. & Anzenbacher, P., 26 Jul 2017, In : Chemistry - A European Journal. 23, 42, p. 10222-10229 8 p.

Research output: Contribution to journalArticle

Open Access
File
Assays
Screening
Throughput
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Self assembly
20 Citations (Scopus)

Long-wavelength fluorescent boronate probes for the detection and intracellular imaging of peroxynitrite

Sedgwick, A. C., Han, H. H., Gardiner, J. E., Bull, S. D., He, X-P. & James, T. D., 11 Dec 2017, In : Chemical Communications. 53, 95, p. 12822-12825

Research output: Contribution to journalArticle

Open Access
Mitochondria
Peroxynitrous Acid
Solubility
Imaging techniques
Wavelength
7 Citations (Scopus)

Low-dimensional materials facilitate the conjugation between fluorogenic boronic acids and saccharides

Guo, S., Chen, J., Cai, B. Y., Chen, W. W., Li, Y. F., Sun, X., Chen, G. R., He, X. P. & James, T. D., 1 Jan 2017, In : Materials Chemistry Frontiers. 1, 1, p. 61-64 4 p.

Research output: Contribution to journalArticle

Open Access
7 Citations (Scopus)

Lysosomal tracking with a cationic naphthalimide using multiphoton fluorescence lifetime imaging microscopy

Li, M., Ge, H., Mirabello, V., Arrowsmith, R. L., Kociok-Kohn, G., Botchway, S. W., Zhu, W., Pascu, S. I. & James, T. D., 18 Oct 2017, In : Chemical Communications. 53, 81, p. 11161-11164

Research output: Contribution to journalArticle

Open Access
File
Naphthalimides
Microscopic examination
Fluorescence
Imaging techniques
Protonation
8 Citations (Scopus)

Macrophage Migration Inhibitory Factor is subjected to glucose modification and oxidation in Alzheimer's Disease

Kassaar, O., Pereira Morais, M., Xu, S., Adam, E. L., Chamberlain, R. C., Jenkins, B., James, T., Francis, P. T., Ward, S., Williams, R. J. & Van Den Elsen, J., 23 Feb 2017, In : Scientific Reports. 7, 42874.

Research output: Contribution to journalArticle

Open Access
Macrophage Migration-Inhibitory Factors
Alzheimer Disease
Glucose
Hyperglycemia
Aptitude
14 Citations (Scopus)

Photochromism and molecular logic gate operation of a water-compatible bis-glycosyl diarylethene

Chai, X., Fu, Y. X., James, T. D., Zhang, J., He, X-P. & Tian, H., 1 Aug 2017, In : Chemical Communications. 53, 68, p. 9494-9497 4 p.

Research output: Contribution to journalArticle

Open Access
Photochromism
Logic gates
Water
6 Citations (Scopus)

Rapid determination of enantiomeric excess via NMR spectroscopy: A research-informed experiment

Fossey, J. S., Anslyn, E. V., Brittain, W. D. G., Bull, S. D., Chapin, B. M., Le Duff, C. S., James, T. D., Lees, G., Lim, S., Lloyd, J. A. C., Manville, C. V., Payne, D. T. & Roper, K. A., 10 Jan 2017, In : Journal of Chemical Education. 94, 1, p. 79-84 6 p.

Research output: Contribution to journalArticle

Open Access
Nuclear magnetic resonance spectroscopy
experiment
Experiments
Teaching
chemistry