Tony James

Royal Society Wolfson Research Merit Award Holder, Fellow of the Royal Society of Chemistry, Prof

  • 1 SOUTH 0.21

Accepting PhD Students

1987 …2022

Research output per year

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Research Output

2020
2 Downloads (Pure)

Activity-Based Sensing: Achieving Chemical Selectivity through Chemical Reactivity

Chang, C. J., James, T. D., New, E. J. & Tang, B. Z., 21 Jan 2020, In : Accounts of Chemical Research. 53, 1, p. 1 1 p.

Research output: Contribution to journalEditorial

A fluorogenic probe for tracking GSH flux in developing neurons

Zong, H., Peng, J., Li, X. R., Liu, M., Hu, Y., Li, J., Zang, Y., Li, X. & James, T. D., 7 Jan 2020, In : Chemical communications (Cambridge, England). 56, 4, p. 515-518 4 p.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)
Open Access
File
3 Citations (Scopus)
3 Downloads (Pure)

A Three-Component Derivatization Protocol for Determining the Enantiopurity of Sulfinamides by 1H and 19F NMR Spectroscopy

Groleau, R. R., Chapman, R. S. L., Ley-Smith, H., Liu, L., James, T. D. & Bull, S. D., 17 Jan 2020, In : Journal of Organic Chemistry. 85, 2, p. 1208-1215

Research output: Contribution to journalArticle

Open Access

Bio-Conjugated Advanced Materials for Targeted Disease Theranostics

Hu, X. L., Kwon, N., Yan, K. C., Sedgwick, A. C., Chen, G. R., He, X. P., James, T. D. & Yoon, J., 3 Feb 2020, In : Advanced Functional Materials. 1907906.

Research output: Contribution to journalReview article

Colorimetric assay for the rapid determination of free-base nicotine in e-liquid

Huang, Y. J., Deng, Q. X., Lan, H. Q., Fang, Z. Z., Chen, H., Lin, Y., Xu, H. C., James, T. D. & Xie, W., 14 Jan 2020, In : Analytical Methods. 12, 2, p. 193-199 7 p.

Research output: Contribution to journalArticle

Correction: Fluorescence imaging of a potential diagnostic biomarker for breast cancer cells using a peptide-functionalized fluorogenic 2D material

Dou, W. T., Liu, L. F., Gao, J., Zang, Y., Chen, G. R., Field, R. A., James, T. D., Li, J. & He, X. P., 14 Jan 2020, In : Chemical Communications. 56, 4, p. 664-664 1 p.

Research output: Contribution to journalArticle

Open Access

Mechanistic insights into the novel glucose-sensitive behavior of P(NIPAM-co-2-AAPBA)

Wang, Q., Fu, M., Guan, Y., James, T. D. & Zhang, Y., 18 Feb 2020, In : Science China Chemistry.

Research output: Contribution to journalArticle

Mechanistic insights into the origin of substituent-directed product Z–E selectivity for gold-catalyzed [4+1]-annulations of 1,4-diyn-3-ols with isoxazoles: A DFT study

Wang, K., Liu, Y., Wu, Q., Liu, L., Li, Y., James, T. D., Chen, G. & Bi, S., 1 Jan 2020, In : Molecular Catalysis. 480, p. 1-9 9 p., 110647.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Protein encapsulation: A new approach for improving the capability of small-molecule fluorogenic probes

Han, H. H., Sedgwick, A. C., Shang, Y., Li, N., Liu, T., Li, B. H., Yu, K., Zang, Y., Brewster, J. T., Odyniec, M. L., Weber, M., Bull, S. D., Li, J., Sessler, J. L., James, T. D., He, X. P. & Tian, H., 28 Jan 2020, In : Chemical Science. 11, 4, p. 1107-1113 7 p.

Research output: Contribution to journalArticle

Open Access
Open Access

Special issue on “Fluorescent probes”

Sedgwick, A. C. & James, T. D., Feb 2020, In : Frontiers of Chemical Science and Engineering. 14, 1, p. 1-13

Research output: Contribution to journalEditorial

2019

A boronic acid-based fluorescent hydrogel for monosaccharide detection

Xu, S., Sedgwick, A. C., Elfeky, S. A., Chen, W., Jones, A. S., Williams, G. T., Jenkins, A. T. A., Bull, S. D., Fossey, J. S. & James, T. D., 21 May 2019, In : Frontiers of Chemical Science and Engineering.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

A far-red fluorescent probe for sensing laccase in fungi and its application in developing an effective biocatalyst for the biosynthesis of antituberculous dicoumarin

Tian, Z., Yan, Q., Feng, L., Deng, S., Wang, C., Cui, J., Wang, C., Zhang, Z., James, T. D. & Ma, X., 7 Apr 2019, In : Chemical Communications. 55, 27, p. 3951-3954 4 p.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

A Leucine Aminopeptidase-Activated Theranostic Prodrug for Cancer Diagnosis and Chemotherapy

Wang, F., Hu, S., Sun, Q., Fei, Q., Ma, C., Lu, C., Nie, J., Chen, Z., Ren, J., Chen, G. R., Yang, G., He, X. P. & James, T. D., 18 Nov 2019, In : ACS Applied Bio Materials. 2, 11, p. 4904-4910 7 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

A practical graphitic carbon nitride (g-C3N4)based fluorescence sensor for the competitive detection of trithiocyanuric acid and mercury ions

Li, M., Wang, B., An, X., Li, Z., Zhu, H., Mao, B., Calatayud, D. G. & James, T. D., 1 Nov 2019, In : Dyes and Pigments. 170, 107476.

Research output: Contribution to journalArticle

1 Citation (Scopus)

A Simple Near-Infrared Fluorescent Probe for the Detection of Peroxynitrite

Wu, L., Tian, X., Han, H. H., Wang, J., Groleau, R. R., Tosuwan, P., Wannalerse, B., Sedgwick, A. C., Bull, S. D., He, X. P. & James, T. D., 9 Dec 2019, In : ChemistryOpen. 8, 12, p. 1407-1409 3 p.

Research output: Contribution to journalArticle

Open Access

Azulene-Derived Fluorescent Probe for Bioimaging: Detection of Reactive Oxygen and Nitrogen Species by Two-Photon Microscopy

Murfin, L. C., Weber, M., Park, S. J., Kim, W. T., Lopez-Alled, C. M., McMullin, C. L., Pradaux-Caggiano, F., Lyall, C. L., Kociok-Köhn, G., Wenk, J., Bull, S. D., Yoon, J., Kim, H. M., James, T. D. & Lewis, S. E., 11 Dec 2019, In : Journal of the American Chemical Society. 141, 49, p. 19389-19396 8 p.

Research output: Contribution to journalArticle

Open Access
File
1 Downloads (Pure)
Open Access
File
4 Citations (Scopus)
29 Downloads (Pure)
Open Access

Correction to: Molecular Design Strategy to Construct the Near-Infrared Fluorescent Probe for Selectively Sensing Human Cytochrome P450 2J2 (Journal of the American Chemical Society (2019) 141 (1126-1134) DOI: 10.1021/jacs.8b12136)

Ning, J., Liu, T., Dong, P., Wang, W., Ge, G., Wang, B., Yu, Z., Shi, L., Tian, X., Huo, X., Feng, L., Wang, C., Sun, C., Cui, J., James, T. D. & Ma, X., 21 Aug 2019, In : Journal of the American Chemical Society. 141, 33, p. 1-1 1 p., 13278.

Research output: Contribution to journalArticle

Coumarin-based fluorescent 'AND' logic gate probes for the detection of homocysteine and a chosen biological analyte

Wu, L., Gardiner, J. E., Kumawat, L. K., Han, H. H., Guo, R., Li, X., He, X. P., Elmes, R. B. P., Sedgwick, A. C., Bull, S. D. & James, T. D., 27 Aug 2019, In : RSC Advances. 9, 45, p. 26425-26428 4 p.

Research output: Contribution to journalArticle

Open Access

Dual enzyme activated fluorescein based fluorescent probe

Odyniec, M. L., Gardiner, J. E., Sedgwick, A. C., He, X. P., Bull, S. D. & James, T. D., 1 Mar 2019, In : Frontiers of Chemical Science and Engineering.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

Endoplasmic Reticulum Targeting Ratiometric Fluorescent Probe for Carboxylesterase 2 Detection in Drug-Induced Acute Liver Injury

Tian, X., Yan, F., Zheng, J., Cui, X., Feng, L., Li, S., Jin, L., James, T. D. & Ma, X., 17 Dec 2019, In : Analytical Chemistry. 91, 24, p. 15840-15845 6 p.

Research output: Contribution to journalArticle

ESIPT-based fluorescence probe for the ratiometric detection of superoxide

Wu, L., Liu, L., Han, H. H., Tian, X., Odyniec, M. L., Feng, L., Sedgwick, A. C., He, X. P., Bull, S. D. & James, T. D., 21 Feb 2019, In : New Journal of Chemistry. 43, 7, p. 2875-2877 3 p.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

Evaluation of HOCl-generating anticancer agents by an ultrasensitive dual-mode fluorescent probe

Shi, D., Chen, S., Dong, B., Zhang, Y., Sheng, C., James, T. D. & Guo, Y., 7 Apr 2019, In : Chemical Science. 10, 13, p. 3715-3722 8 p.

Research output: Contribution to journalArticle

Open Access
14 Citations (Scopus)

Fluorescence imaging of a potential diagnostic biomarker for breast cancer cells using a peptide-functionalized fluorogenic 2D material

Dou, W. T., Liu, L. F., Gao, J., Zang, Y., Chen, G. R., Field, R. A., James, T. D., Li, J. & He, X. P., 14 Nov 2019, In : Chemical communications (Cambridge, England). 55, 88, p. 13235-13238 4 p.

Research output: Contribution to journalArticle

Open Access

Fluorescent probes for bioactive detection and imaging of phase II metabolic enzymes

Feng, L., Ning, J., Tian, X., Wang, C., Zhang, L., Ma, X. & James, T. D., 15 Nov 2019, In : Coordination Chemistry Reviews. 399, 213026.

Research output: Contribution to journalReview article

3 Citations (Scopus)

Identification of novel small-molecule inhibitors of α-methylacyl-CoA racemase (AMACR; P504S) and structure-activity relationships

Petrova, Y., Wadda, K., Nathubhai, A., Jevglevskis, M., Mitchell, P., James, T., Threadgill, M., Woodman, T. & Lloyd, M., 1 Nov 2019, In : Bioorganic Chemistry. 92, 103264.

Research output: Contribution to journalArticle

Long Wavelength TCF-Based Fluorescent Probe for the Detection of Alkaline Phosphatase in Live Cells

Gwynne, L., Sedgwick, A. C., Gardiner, J. E., Williams, G. T., Kim, G., Maillard, J. Y., Jenkins, T., Bull, S. D., Sessler, J. L., Yoon, J. & James, T. D., 30 Apr 2019, In : Frontiers in Chemistry. 7, APR, p. 1-6 6 p., 255.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

Molecular Design Strategy to Construct the Near-Infrared Fluorescent Probe for Selectively Sensing Human Cytochrome P450 2J2

Ning, J., Liu, T., Dong, P., Wang, W., Ge, G., Wang, B., Yu, Z., Shi, L., Tian, X., Huo, X., Feng, L., Wang, C., Sun, C., Cui, J-N., James, T. D. & Ma, X., 16 Jan 2019, In : Journal of the American Chemical Society. 141, 2, p. 1126-1134 9 p.

Research output: Contribution to journalArticle

Open Access
File
33 Citations (Scopus)
9 Downloads (Pure)

Multiphoton fluorescence lifetime imaging microscopy (FLIM) and super-resolution fluorescence imaging with a supramolecular biopolymer for the controlled tagging of polysaccharides

Ge, H., Cortezon-Tamarit, F., Wang, H. C., Sedgwick, A. C., Arrowsmith, R. L., Mirabello, V., Botchway, S. W., James, T. D. & Pascu, S. I., 21 May 2019, In : Nanoscale. 11, 19, p. 9498-9507 10 p.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

NAG-targeting fluorescence based probe for precision diagnosis of kidney injury

Yan, F., Tian, X., Luan, Z., Feng, L., Ma, X. & James, T. D., 14 Feb 2019, In : Chemical communications (Cambridge, England). 55, 13, p. 1955-1958 4 p.

Research output: Contribution to journalArticle

Open Access
4 Citations (Scopus)

Novel 2-arylthiopropanoyl-CoA inhibitors of α-methylacyl-CoA racemase 1A (AMACR; P504S) as potential anti-prostate cancer agents

Jevglevskis, M., Nathubhai, A., Wadda, K., Lee, G. L., Al-Rawi, S., Jiao, T., Mitchell, P., James, T., Threadgill, M., Woodman, T. & Lloyd, M., 1 Nov 2019, In : Bioorganic Chemistry. 92, 103263.

Research output: Contribution to journalArticle

Open Access
File
66 Downloads (Pure)

Peroxynitrite Activated Drug Conjugate Systems Based on a Coumarin Scaffold Toward the Application of Theranostics

Odyniec, M. L., Han, H. H., Gardiner, J. E., Sedgwick, A. C., He, X. P., Bull, S. D. & James, T. D., 5 Dec 2019, In : Frontiers in Chemistry. 7, 775.

Research output: Contribution to journalArticle

Open Access

Ratiometric fluorescent probe for sensing Streptococcus mutans glucosyltransferase, a key factor in the formation of dental caries

Feng, L., Yan, Q., Zhang, B., Tian, X., Wang, C., Yu, Z., Cui, J., Guo, D., Ma, X. & James, T. D., 25 Mar 2019, In : Chemical Communications. 55, 24, p. 3548-3551 4 p.

Research output: Contribution to journalArticle

Open Access
5 Citations (Scopus)

Ratiometric two-photon fluorescent probe for: In situ imaging of carboxylesterase (CE)-mediated mitochondrial acidification during medication

Jiang, A., Chen, G., Xu, J., Liu, Y., Zhao, G., Liu, Z., Chen, T., Li, Y. & James, T. D., 28 Sep 2019, In : Chemical Communications. 55, 76, p. 11358-11361 4 p.

Research output: Contribution to journalArticle

Open Access
6 Citations (Scopus)

Reaction-Based Fluorescent Probes for the Detection and Imaging of Reactive Oxygen, Nitrogen, and Sulfur Species

Wu, L., Sedgwick, A. C., Sun, X., Bull, S. D., He, X. P. & James, T. D., 17 Sep 2019, In : Accounts of Chemical Research. 52, 9, p. 2582-2597 16 p.

Research output: Contribution to journalArticle

Open Access
6 Citations (Scopus)

Reaction-based indicator displacement assay (RIA) for the development of a triggered release system capable of biofilm inhibition

Patenall, B. L., Williams‡, G. T., Gwynne, L., Stephens, L. J., Lampard, E. V., Hathaway, H. J., Thet, N. T., Young, A. E., Sutton, M. J., Short, R. D., Bull, S. D., James, T. D., Sedgwick, A. C. & Jenkins, A. T. A., 12 Dec 2019, In : Chemical Communications. 55, 100, p. 15129-15132 4 p.

Research output: Contribution to journalArticle

Open Access

Target Enzyme-Activated Two-Photon Fluorescent Probes: A Case Study of CYP3A4 Using a Two-Dimensional Design Strategy

Ning, J., Wang, W., Ge, G., Chu, P., Long, F., Yang, Y., Peng, Y., Feng, L., Ma, X. & James, T. D., 15 Jul 2019, In : Angewandte Chemie - International Edition. 58, 29, p. 9959-9963 5 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

The mechanisms of boronate ester formation and fluorescent turn-on in ortho-aminomethylphenylboronic acids

Sun, X., Chapin, B. M., Metola, P., Collins, B., Wang, B., James, T. D. & Anslyn, E. V., 1 Sep 2019, In : Nature Chemistry. 11, 9, p. 768-778 11 p.

Research output: Contribution to journalReview article

Open Access
File
3 Citations (Scopus)
3 Downloads (Pure)

Voltammetric characterisation of diferrocenylborinic acid in organic solution and in aqueous media when immobilised into a titanate nanosheet film

Konhefr, M., Sedgwick, A. C., James, T. D., Lacina, K., Skládal, P., Putra, B. R., Harito, C., Bavykin, D. V., Walsh, F. C., Raithby, P. R., Kociok-Köhn, G. & Marken, F., 14 Aug 2019, In : Dalton transactions (Cambridge, England : 2003). 48, 30, p. 11200-11207 8 p.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)
2018

A fluorescent peptidyl substrate for visualizing peptidyl-prolyl cis/trans isomerase activity in live cells

Jiang, Q., Li, X-R., Wang, C-K., Cheng, J., Tan, C., Cui, T-T., Lu, N-N., James, T. D., Han, F. & Li, X., 21 Feb 2018, In : Chemical communications (Cambridge, England). 54, 15, p. 1857-1860 4 p.

Research output: Contribution to journalArticle

Open Access
File
3 Citations (Scopus)
25 Downloads (Pure)

A hemicyanine based ratiometric fluorescence probe for mapping lysosomal pH during heat stroke in living cells

Wu, L., Wang, Y., James, T. D., Jia, N. & Huang, C., 4 Jun 2018, In : Chemical Communications. 54, 44, p. 5518-5521 4 p.

Research output: Contribution to journalArticle

Open Access
29 Citations (Scopus)

Analysis of Protein Glycation Using Phenylboronate Acrylamide Gel Electrophoresis

Pereira Morais, M., Munir, O. K., Flower, S., Williams, R. J., James, T. & Van Den Elsen, J., 14 Nov 2018, Electrophoretic Separation of Proteins: Methods and Protocols. T. Kurien, B. & Hal Scofield, R. (eds.). New York, U. S. A.: Humana Press, p. 161-175 (Methods in Molecular Biology; vol. 1855).

Research output: Chapter in Book/Report/Conference proceedingChapter

A naphthoimidazolium-cholesterol derivative as a ratiometric fluorescence based chemosensor for the chiral recognition of carboxylates

Zhang, X., Ko, G., Joung, J. F., Li, M., Jeong, Y., Swamy, K. M. K., Lee, D., Liu, Y., Lee, S., Park, S., James, T. D. & Yoon, J., 22 Nov 2018, In : Chemical communications (Cambridge, England). 54, 94, p. 13264-13267 4 p.

Research output: Contribution to journalArticle

Open Access
3 Citations (Scopus)

'AND'-based fluorescence scaffold for the detection of ROS/RNS and a second analyte

Odyniec, M. L., Sedgwick, A. C., Swan, A. H., Weber, M., Tang, T. M. S., Gardiner, J. E., Zhang, M., Jiang, Y. B., Kociok-Kohn, G., Elmes, R. B. P., Bull, S. D., He, X. P. & James, T. D., 27 Jun 2018, In : Chemical Communications. 54, p. 8466-8469 4 p.

Research output: Contribution to journalArticle

Open Access
14 Citations (Scopus)

An ESIPT Probe for the Ratiometric Imaging of Peroxynitrite Facilitated by Binding to Aβ-Aggregates

Sedgwick, A. C., Dou, W. T., Jiao, J. B., Wu, L., Williams, G. T., Jenkins, A. T. A., Bull, S. D., Sessler, J. L., He, X. P. & James, T. D., 31 Oct 2018, In : Journal of the American Chemical Society. 140, 43, p. 14267-14271 5 p.

Research output: Contribution to journalArticle

Open Access
34 Citations (Scopus)