Tony James

Royal Society Wolfson Research Merit Award Holder, Fellow of the Royal Society of Chemistry, Prof

  • 1 SOUTH 0.21

Accepting PhD Students

1987 …2022
If you made any changes in Pure these will be visible here soon.

Research Output 1987 2018

2018
2 Citations

A fluorescent peptidyl substrate for visualizing peptidyl-prolyl cis/trans isomerase activity in live cells

Jiang, Q., Li, X-R., Wang, C-K., Cheng, J., Tan, C., Cui, T-T., Lu, N-N., James, T. D., Han, F. & Li, X., 21 Feb 2018, In : Chemical communications (Cambridge, England). 54, 15, p. 1857-1860 4 p.

Research output: Contribution to journalArticle

Peptidylprolyl Isomerase
Imaging techniques
Communication
Substrates
Fluorescent Dyes
1 Citations

A hemicyanine based ratiometric fluorescence probe for mapping lysosomal pH during heat stroke in living cells

Wu, L., Wang, Y., James, T. D., Jia, N. & Huang, C., 11 Apr 2018, In : Chemical Communications. 54, p. 5518-5521 4 p.

Research output: Contribution to journalArticle

Open Access
Fluorescence
Cells
Fluorophores
Neurology
Fluorescent Dyes

Analysis of Protein Glycation Using Phenylboronate Acrylamide Gel Electrophoresis

Pereira Morais, M., Munir, O. K., Flower, S., Williams, R. J., James, T. & Van Den Elsen, J., 14 Nov 2018, Electrophoretic Separation of Proteins. Kurien, B. & Scofield, R. (eds.). New York, U. S. A.: Humana Press, p. 161-175 (Methods in Molecular Biology; vol. 1855).

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Citations

'AND'-based fluorescence scaffold for the detection of ROS/RNS and a second analyte

Odyniec, M. L., Sedgwick, A. C., Swan, A. H., Weber, M., Tang, T. M. S., Gardiner, J. E., Zhang, M., Jiang, Y. B., Kociok-Kohn, G., Elmes, R. B. P., Bull, S. D., He, X. P. & James, T. D., 27 Jun 2018, In : Chemical Communications. 54, p. 8466-8469 4 p.

Research output: Contribution to journalArticle

Open Access
Scaffolds
Fluorescence
Biomarkers
Esterases
Fluorescent Dyes

An ESIPT Probe for the Ratiometric Imaging of Peroxynitrite Facilitated by Binding to Aβ-Aggregates

Sedgwick, A. C., Dou, W. T., Jiao, J. B., Wu, L., Williams, G. T., Jenkins, A. T. A., Bull, S. D., Sessler, J. L., He, X. P. & James, T. D., 2018, In : Journal of the American Chemical Society. 140, 43, p. 14267-14271

Research output: Contribution to journalArticle

Open Access
4 Citations

A quick and selective rhodamine based “smart probe” for “signal-on” optical detection of Cu2+ and Al3+ in water, cell imaging, computational studies and solid state analysis

Rai, A., Singh, A. K., Tripathi, K., Sonkar, A. K., Chauhan, B. S., Srikrishna, S., James, T. D. & Mishra, L., 1 Aug 2018, In : Sensors and Actuators B: Chemical. 266, p. 95-105

Research output: Contribution to journalArticle

Rhodamines
rhodamine
solid state
Imaging techniques
Water
5 Citations
Open Access
File
Fructose
Bolts
Boronic Acids
Acids
Fluorescence
1 Citations

A simple umbelliferone based fluorescent probe for the detection of nitroreductase

Sedgwick, A. C., Hayden, A., Hill, B., Bull, S. D., Elmes, R. B. P. & James, T. D., 1 Jun 2018, In : Frontiers of Chemical Science and Engineering. 12, 2, p. 311-314 4 p.

Research output: Contribution to journalArticle

7-hydroxycoumarin
Nitroreductases
Fluorescent Dyes
Enzymes
Fluorophores
1 Citations

Biodegradable macroporous scaffold with nano-crystal surface microstructure for highly effective osteogenesis and vascularization

Chu, L., Jiang, G., Hu, X., James, T. D., He, X-P., Li, Y. & Tang, T., 21 Mar 2018, In : Journal of Materials Chemistry B . 6, 11, p. 1658-1667

Research output: Contribution to journalArticle

Scaffolds
Scaffolds (biology)
Crystals
Microstructure
Calcium
2 Citations

Boronate-Based Fluorescence Probes for the Detection of Hydrogen Peroxide

Lampard, E. V., Sedgwick, A. C., Sun, X., Filer, K. L., Hewins, S. C., Kim, G., Yoon, J., Bull, S. D. & James, T. D., 1 Mar 2018, In : ChemistryOpen. 7, 3, p. 262-265

Research output: Contribution to journalArticle

Open Access

Correction: Boronate based fluorescence (ESIPT) probe for peroxynitrite(Chem. Commun. (2016) 52 (12350–12352) DOI: 10.1039/C6CC06829D)

Sedgwick, A. C., Sun, X., Kim, G., Yoon, J., Bull, S. D. & James, T. D., 28 Sep 2018, In : Chemical Communications. 54, 76, p. 10775 1 p.

Research output: Contribution to journalArticle

Open Access

Correction: A bodipy based hydroxylamine sensor (Chemical Communications (2017) 53 (10441-10443) DOI: 10.1039/C7CC05872A)

Sedgwick, A. C., Chapman, R. S. L., Gardiner, J. E., Peacock, L. R., Kim, G., Yoon, J., Bull, S. D. & James, T. D., 4 Oct 2018, In : Chemical Communications. 54, 77, p. 10922 1 p.

Research output: Contribution to journalArticle

Open Access
3 Citations

Dual-function cellulose composites for fluorescence detection and removal of fluoride

Li, M., Liu, Z., Wang, H. C., Sedgwick, A. C., Gardiner, J. E., Bull, S. D., Xiao, H. N. & James, T. D., 1 Feb 2018, In : Dyes and Pigments. 149, p. 669-675 7 p.

Research output: Contribution to journalArticle

Fluorides
Cellulose
Fluorescence
Adsorption
Composite materials

Dye Displacement Assay for Saccharides using Benzoxaborole Hydrogels

Lampard, E. V., Sedgwick, A. C., Sombuttan, T., Williams, G. T., Wannalerse, B., Jenkins, A. T. A., Bull, S. D. & James, T. D., 1 Mar 2018, In : ChemistryOpen. 7, 3, p. 266-268

Research output: Contribution to journalArticle

Open Access
Hydrogels
Assays
Coloring Agents
Boronic Acids
Monosaccharides
1 Citations

ESIPT-based fluorescence probe for the rapid detection of hypochlorite (HOCl/ClO-)

Wu, L., Yang, Q., Liu, L., Sedgwick, A. C., Cresswell, A. J., Bull, S. D., Huang, C. & James, T. D., 4 Jul 2018, In : Chemical Communications. 54, 61, p. 8522-8525 4 p.

Research output: Contribution to journalArticle

Open Access
Hypochlorous Acid
Fluorescence
Water
Logic gates
Potable water

ESIPT-based fluorescence probe for the rapid detection of peroxynitrite ‘AND' biological thiols

Wu, L., Han, H. H., Liu, L., Gardiner, J. E., Sedgwick, A. C., Huang, C., Bull, S. D., He, X. P. & James, T. D., 14 Oct 2018, In : Chemical Communications. 54, 80, p. 11336-11339 4 p.

Research output: Contribution to journalArticle

Open Access
1 Citations

ESIPT-based ratiometric fluorescence probe for the intracellular imaging of peroxynitrite

Wu, L., Wang, Y., Weber, M., Liu, L., Sedgwick, A. C., Bull, S. D., Huang, C. & James, T. D., 7 Aug 2018, In : Chemical Communications. 54, 71, p. 9953-9956 4 p.

Research output: Contribution to journalArticle

Open Access
Peroxynitrous Acid
Fluorescent Dyes
Fluorescence
Imaging techniques
Experiments

Fluorescence based Tool to Detect Endogenous Peroxynitrite in M1-Polarized Murine J774.2 Macrophages

Weber, M., Mackenzie, A. B., Bull, S. D. & James, T. D., 4 Sep 2018, In : Analytical Chemistry. 90, 17, p. 10621–10627 7 p.

Research output: Contribution to journalArticle

Open Access
File
Peroxynitrous Acid
Macrophages
Reactive Oxygen Species
Fluorescence
Oxidative stress
4 Citations

Fluorescence detection and removal of copper from water using a biobased and biodegradable 2D soft material

Li, M., Liu, Z., Wang, S., Calatayud, D. G., Zhu, W. H., James, T. D., Wang, L., Mao, B. & Xiao, H. N., 7 Jan 2018, In : Chemical Communications. 54, 2, p. 184-187 4 p.

Research output: Contribution to journalArticle

Open Access
Metal ions
Copper
Fluorescence
Graphite
Water
2 Citations

Long-wavelength TCF-based fluorescence probes for the detection and intracellular imaging of biological thiols

Sedgwick, A. C., Gardiner, J. E., Kim, G., Yevglevskis, M., Lloyd, M. D., Jenkins, A. T. A., Bull, S. D., Yoon, J. & James, T. D., 2018, In : Chemical Communications. 54, 38, p. 4786-4789 4 p.

Research output: Contribution to journalArticle

Open Access
Sulfhydryl Compounds
Toxicity
Fluorescence
Drug therapy
Imaging techniques
16 Citations

Molecular logic gates: the past, present and future

Erbas-cakmak, S., Kolemen, S., Sedgwick, A. C., Gunnlaugsson, T., James, T. D., Yoon, J. & Akkaya, E. U., 1 Mar 2018, In : Chemical Society Reviews. 47, 7, p. 2228-2248 21 p.

Research output: Contribution to journalReview article

Open Access
Logic gates
Silicon
Integrated circuits
Tissue
Molecules

Osteogenesis, vascularization and osseointegration of a bioactive multiphase macroporous scaffold in the treatment of large bone defects

Chu, L., Jiang, G., Hu, X., James, T. D., He, X-P., Li, Y. & Tang, T., 2018, In : Journal of Materials Chemistry B . 6, 25, p. 4197-4204 10 p.

Research output: Contribution to journalArticle

Scaffolds
Bone
Defects
Bone Substitutes
Biocompatible Materials

Preferential colonization of osteoblasts over co-cultured bacteria on a bifunctional biomaterial surface

Chu, L., Yang, Y., Yang, S., Fan, Q., Yu, Z., Hu, X. L., James, T. D., He, X. P. & Tang, T., 2 Oct 2018, In : Frontiers in Microbiology. 9, OCT, 2219.

Research output: Contribution to journalArticle

Open Access
1 Citations

Promoting magnesium sulfite oxidation: Via partly oxidized metal nanoparticles on graphitic carbon nitride (g-C3N4) in the magnesia desulfurization process

Li, M., Qi, T., Yang, R., Xiao, H. N., Fang, Z., Hodge, S. A., James, T. D., Wang, L. & Mao, B., 28 Jun 2018, In : Journal of Materials Chemistry A. 6, 24, p. 11296-11305 10 p.

Research output: Contribution to journalArticle

Magnesium Oxide
Sulfites
Carbon nitride
Metal nanoparticles
Magnesia

Selective Cu2+ Ion Sensing by Nanoaggregates of Pyridyl-2,6-bis(3-allylsalicylaldehyde)hydrazone

Rai, A., Tripathi, K., Kumar Sonkar, A., James, T. D., Yashaswee, S., Kumar Trigun, S. & Mishra, L., 24 May 2018, In : ChemistrySelect. 3, 19, p. 5395-5400 6 p.

Research output: Contribution to journalArticle

Hydrazones
Ions
Cells
Water

Structure-activity relationships of rationally designed AMACR 1A inhibitors

Jevglevskis, M., Lee, G. L., Nathubhai, A., Petrova, Y., James, T., Threadgill, M., Woodman, T. & Lloyd, M., 1 Sep 2018, In : Bioorganic and Medicinal Chemistry. 79, p. 145-154 10 p.

Research output: Contribution to journalArticle

Acyl Coenzyme A
Enzyme activity
Coenzyme A
Assays
Esters

Supramolecular glyco-poly-cyclodextrin functionalized 2D probe for targeted stimulus-responsive bioimaging

Wang, H., Liu, Y., Xu, C., Wang, X., Chen, G-R., James, T. D., Zang, Y., Li, J., Ma, X. & He, X-P., 18 Apr 2018, In : Chemical Communications. 54, 32, p. 4037-4040

Research output: Contribution to journalArticle

Cyclodextrins
Cells
7 Citations

The development of a novel AND logic based fluorescence probe for the detection of peroxynitrite and GSH

Sedgwick, A. C., Han, H. H., Gardiner, J. E., Bull, S. D., He, X-P. & James, T. D., 21 Apr 2018, In : Chemical Science. 9, 15, p. 3672-3676

Research output: Contribution to journalArticle

Open Access
Peroxynitrous Acid
Fluorescence
Fluorescein
Imaging techniques
Experiments

Virtual Issue: Chemosensors

Sedgwick, A. C. & James, T. D., 1 Mar 2018, In : ChemistryOpen. 7, 3, p. 215-216 2 p.

Research output: Contribution to journalEditorial

Open Access
Fluorescence
Molecular interactions
Public health
Agriculture
Imaging techniques
2017
2 Citations

A 1-hydroxy-2,3,1-benzodiazaborine-containing π-conjugated system: synthesis, optical properties and solvent-dependent response toward anions

Satta, Y., Nishiyabu, R., James, T. D. & Kubo, Y., 13 Apr 2017, In : Tetrahedron. 73, 15, p. 2053-2061 9 p.

Research output: Contribution to journalArticle

File
Optical Devices
Dimethyl Sulfoxide
Anions
Boron
Optical properties
7 Citations

A bodipy based hydroxylamine sensor

Sedgwick, A. C., Chapman, R. S. L., Gardiner, J. E., Peacock, L. R., Kim, G., Yoon, J., Bull, S. D. & James, T. D., 25 Sep 2017, In : Chemical Communications. 53, 75, p. 10441-10443

Research output: Contribution to journalArticle

Open Access
Hydroxylamine
Fluorescence
Sensors

A convenient colorimetric assay for α-methylacyl-CoA racemase (AMACR; P504S) and testing of inhibitors

Jevglevskis, M., Lee, G. L., Nathubhai, A., James, T., Threadgill, M., Woodman, T. & Lloyd, M., 21 Apr 2017, (Unpublished).

Research output: Contribution to conferenceAbstract

File
Coenzyme A
Inhibitory Concentration 50
Acyl Coenzyme A
Prostatic Neoplasms
S 10
8 Citations

A fluorogenic 2D glycosheet for the simultaneous identification of human-and avian-receptor specificity in influenza viruses

Song, J. X., Tang, X. Y., Zhou, D. M., Zhang, W., James, T. D., He, X-P. & Tian, H., 7 Mar 2017, In : Materials Horizons. 4, 3, p. 431-436 6 p.

Research output: Contribution to journalArticle

Open Access
Viruses
Polysaccharides
Color
Fluorophores
Switches
2 Citations

A novel colorimetric assay for α-methylacyl-CoA racemase 1A (AMACR; P504S) utilizing the elimination of 2,4-dinitrophenolate

Jevglevskis, M., Lee, G. L., Nathubhai, A., Petrova, Y., James, T., Threadgill, M., Woodman, T. & Lloyd, M., 7 May 2017, In : Chemical Communications. 53, 37, p. 5087-5090 4 p.

Research output: Contribution to journalArticle

Open Access
Assays
Ibuprofen
Fatty acids
Fatty Acids
Degradation
9 Citations

Azulene–boronate esters: colorimetric indicators for fluoride in drinking water

Lopez-Alled, C. M., Sanchez Fernandez, A., Edler, K., Sedgwick, A., Bull, S., McMullin, C., Kociok-Kohn, G., James, T., Wenk, J. & Lewis, S., 4 Dec 2017, In : Chemical Communications. 53, 93, p. 12580-12583 4 p.

Research output: Contribution to journalArticle

Open Access
Fluorides
Developing countries
Potable water
Drinking Water
Esters
3 Citations

Behavior of Supramolecular Assemblies of Radiometal-Filled and Fluorescent Carbon Nanocapsules In Vitro and In Vivo

Ge, H., Riss, P. J., Mirabello, V., Calatayud, D. G., Flower, S. E., Arrowsmith, R. L., Fryer, T. D., Hong, Y., Sawiak, S., Jacobs, R. M. J., Botchway, S. W., Tyrrell, R. M., James, T. D., Fossey, J. S., Dilworth, J. R., Aigbirhio, F. I. & Pascu, S. I., 14 Sep 2017, In : Chem. 3, 3, p. 437-460

Research output: Contribution to journalArticle

Open Access
File
Nanocapsules
Carbon Nanotubes
beta-Glucans
Carbon
Optical Imaging

Benzoxaboroles and Boronic Acids for Sensing Applications

Lampard, E., Sep 2017

Research output: ThesisDoctoral Thesis

Open Access
File
Boronic Acids
Sugars
Hydrogels
Esters
Hydrogen Peroxide
7 Citations

Boronic Acid Mediated Coupling of Catechols and N-Hydroxylamines: A Bioorthogonal Reaction to Label Peptides

Meadows, M. K., Roesner, E. K., Lynch, V. M., James, T. D. & Anslyn, E. V., 16 Jun 2017, In : Organic Letters. 19, 12, p. 3179-3182 4 p.

Research output: Contribution to journalArticle

Open Access
File
Hydroxylamines
Catechols
Boronic Acids
peptides
Labels

Carbohydrate Directed Photoaffinity Labelling

Fowle, C., Sep 2017, 136 p.

Research output: ThesisDoctoral Thesis

Open Access
File
Labeling
Carbohydrates
Biological systems
Caseins
Proteins

Electroanalysis in 2D-TiO2 Nanosheet Hosts: Electrolyte and Selectivity Effects in Ferroceneboronic Acid – Saccharide Binding

Tri Wahyuni, W., Marken, F., Putra, B. R., Bavykin, D. V., Walsh, F. C., James, T., Kociok-Kohn, G. & Harito, C., 17 Nov 2017, In : Electroanalysis.

Research output: Contribution to journalArticle

Open Access
File
Nanosheets
Electrolytes
Fructose
Acids
Glucose
5 Citations

Fluorescence Sensing with Cellulose-Based Materials

Li, M., Li, X., Xiao, H. N. & James, T. D., 1 Dec 2017, In : ChemistryOpen. 6, 6, p. 685-696 12 p.

Research output: Contribution to journalReview article

Open Access
Cellulose
Fluorescence
Sensors
Functional materials
Heavy Metals
80 Citations

Fluorescent chemosensors: The past, present and future

Wu, D., Sedgwick, A. C., Gunnlaugsson, T., Akkaya, E. U., Yoon, J. & James, T. D., 7 Dec 2017, In : Chemical Society Reviews. 46, 23, p. 7105-7123 19 p.

Research output: Contribution to journalReview article

Open Access
Physiology
Biotechnology
Ions
Sensors
Direction compound
21 Citations

Fluorescent glycoprobes: a sweet addition for improved sensing

He, X. P., Zang, Y., James, T. D., Li, J., Chen, G. R. & Xie, J., 4 Jan 2017, In : Chemical Communications. 53, 1, p. 82-90 9 p.

Research output: Contribution to journalArticle

Open Access
Fluorescent Dyes
Solubility
Ions
Imaging techniques
Water
3 Citations

Graphene oxide-enhanced cytoskeleton imaging and mitosis tracking

Li, Q. R., Jiao, J. B., Li, L. L., He, X. P., Zang, Y., James, T. D., Chen, G. R., Guo, L. & Li, J., 28 Feb 2017, In : Chemical Communications. 53, 23, p. 3373-3376 4 p.

Research output: Contribution to journalArticle

Open Access
Graphite
Oxides
Graphene
Peptides
Imaging techniques
2 Citations

High-Throughput Assay for Enantiomeric Excess Determination in 1,2- and 1,3-Diols and Direct Asymmetric Reaction Screening

Shcherbakova, E. G., Brega, V., Lynch, V. M., James, T. D. & Anzenbacher, P., 26 Jul 2017, In : Chemistry - A European Journal. 23, 42, p. 10222-10229 8 p.

Research output: Contribution to journalArticle

Open Access
File
Assays
Screening
Throughput
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Self assembly
Photochromism
Fluorescent Dyes
Imaging techniques
Biological systems
Fluorescence
14 Citations

Long-wavelength fluorescent boronate probes for the detection and intracellular imaging of peroxynitrite

Sedgwick, A. C., Han, H. H., Gardiner, J. E., Bull, S. D., He, X-P. & James, T. D., 11 Dec 2017, In : Chemical Communications. 53, 95, p. 12822-12825

Research output: Contribution to journalArticle

Open Access
Mitochondria
Peroxynitrous Acid
Solubility
Imaging techniques
Wavelength
6 Citations

Lysosomal tracking with a cationic naphthalimide using multiphoton fluorescence lifetime imaging microscopy

Li, M., Ge, H., Mirabello, V., Arrowsmith, R. L., Kociok-Kohn, G., Botchway, S. W., Zhu, W., Pascu, S. I. & James, T. D., 18 Oct 2017, In : Chemical Communications. 53, 81, p. 11161-11164

Research output: Contribution to journalArticle

Open Access
File
Naphthalimides
Microscopic examination
Fluorescence
Imaging techniques
Protonation
6 Citations

Macrophage Migration Inhibitory Factor is subjected to glucose modification and oxidation in Alzheimer's Disease

Kassaar, O., Pereira Morais, M., Xu, S., Adam, E. L., Chamberlain, R. C., Jenkins, B., James, T., Francis, P. T., Ward, S., Williams, R. J. & Van Den Elsen, J., 23 Feb 2017, In : Scientific Reports. 7, 42874.

Research output: Contribution to journalArticle

Open Access
Macrophage Migration-Inhibitory Factors
Alzheimer Disease
Glucose
Hyperglycemia
Aptitude
23 Citations

Multiplexed photoluminescent sensors: Towards improved disease diagnostics

He, X. P., Hu, X. L., James, T. D., Yoon, J. & Tian, H., 21 Nov 2017, In : Chemical Society Reviews. 46, 22, p. 6687-6696 10 p.

Research output: Contribution to journalReview article

Open Access
Sensors
Biomarkers
Materials science