Tony James

Royal Society Wolfson Research Merit Award Holder, Fellow of the Royal Society of Chemistry, Prof

  • 1 SOUTH 0.21

Accepting PhD Students

1987 …2022
If you made any changes in Pure these will be visible here soon.

Research Output 1987 2019

2019

A boronic acid-based fluorescent hydrogel for monosaccharide detection

Xu, S., Sedgwick, A. C., Elfeky, S. A., Chen, W., Jones, A. S., Williams, G. T., Jenkins, A. T. A., Bull, S. D., Fossey, J. S. & James, T. D., 21 May 2019, In : Frontiers of Chemical Science and Engineering.

Research output: Contribution to journalArticle

Open Access

A far-red fluorescent probe for sensing laccase in fungi and its application in developing an effective biocatalyst for the biosynthesis of antituberculous dicoumarin

Tian, Z., Yan, Q., Feng, L., Deng, S., Wang, C., Cui, J., Wang, C., Zhang, Z., James, T. D. & Ma, X., 7 Apr 2019, In : Chemical Communications. 55, 27, p. 3951-3954 4 p.

Research output: Contribution to journalArticle

Open Access
14 Citations (Scopus)

A molecular design strategy to construct the near-infrared fluorescent probe for selectively sensing human cytochrome P450 2J2

Ning, J., Liu, T., Dong, P., Wang, W., Ge, G., Wang, B., Yu, Z., Shi, L., Tian, X., Huo, X., Feng, L., Wang, C., Sun, C., Cui, J-N., James, T. D. & Ma, X., 16 Jan 2019, In : Journal of the American Chemical Society. 141, 2, p. 1126-1134 9 p.

Research output: Contribution to journalArticle

A practical graphitic carbon nitride (g-C3N4)based fluorescence sensor for the competitive detection of trithiocyanuric acid and mercury ions

Li, M., Wang, B., An, X., Li, Z., Zhu, H., Mao, B., Calatayud, D. G. & James, T. D., 12 Apr 2019, In : Dyes and Pigments. 170, 107476.

Research output: Contribution to journalArticle

1 Citation (Scopus)
13 Downloads (Pure)
Open Access
File
Open Access

Correction to: Molecular Design Strategy to Construct the Near-Infrared Fluorescent Probe for Selectively Sensing Human Cytochrome P450 2J2 (Journal of the American Chemical Society (2019) 141 (1126-1134) DOI: 10.1021/jacs.8b12136)

Ning, J., Liu, T., Dong, P., Wang, W., Ge, G., Wang, B., Yu, Z., Shi, L., Tian, X., Huo, X., Feng, L., Wang, C., Sun, C., Cui, J., James, T. D. & Ma, X., 21 Aug 2019, In : Journal of the American Chemical Society. 141, 33, 1 p., 13278.

Research output: Contribution to journalArticle

Dual enzyme activated fluorescein based fluorescent probe

Odyniec, M. L., Gardiner, J. E., Sedgwick, A. C., He, X. P., Bull, S. D. & James, T. D., 1 Mar 2019, In : Frontiers of Chemical Science and Engineering.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

ESIPT-based fluorescence probe for the ratiometric detection of superoxide

Wu, L., Liu, L., Han, H. H., Tian, X., Odyniec, M. L., Feng, L., Sedgwick, A. C., He, X. P., Bull, S. D. & James, T. D., 21 Feb 2019, In : New Journal of Chemistry. 43, 7, p. 2875-2877 3 p.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

Evaluation of HOCl-generating anticancer agents by an ultrasensitive dual-mode fluorescent probe

Shi, D., Chen, S., Dong, B., Zhang, Y., Sheng, C., James, T. D. & Guo, Y., 7 Apr 2019, In : Chemical Science. 10, 13, p. 3715-3722 8 p.

Research output: Contribution to journalArticle

Open Access

Fluorescent probes for bioactive detection and imaging of phase II metabolic enzymes

Feng, L., Ning, J., Tian, X., Wang, C., Zhang, L., Ma, X. & James, T. D., 29 Aug 2019, In : Coordination Chemistry Reviews. 399, 213026.

Research output: Contribution to journalReview article

Identification of novel small-molecule inhibitors of α-methylacyl-CoA racemase (AMACR; P504S) and structure-activity relationships

Petrova, Y., Wadda, K., Nathubhai, A., Jevglevskis, M., Mitchell, P., James, T., Threadgill, M., Woodman, T. & Lloyd, M., 7 Sep 2019, In : Bioorganic Chemistry. 92, 103264.

Research output: Contribution to journalArticle

Long wavelength TCF-based fluorescence probe for the detection of Alkaline Phosphatase in live cells

Gwynne, L., Sedgwick, A. C., Gardiner, J. E., Williams, G. T., Kim, G., Maillard, J. Y., Jenkins, T., Bull, S. D., Sessler, J. L., Yoon, J. & James, T. D., 30 Apr 2019, In : Frontiers in Chemistry. 7, APR, 255.

Research output: Contribution to journalArticle

Open Access

Multiphoton fluorescence lifetime imaging microscopy (FLIM) and super-resolution fluorescence imaging with a supramolecular biopolymer for the controlled tagging of polysaccharides

Ge, H., Cortezon-Tamarit, F., Wang, H. C., Sedgwick, A. C., Arrowsmith, R. L., Mirabello, V., Botchway, S. W., James, T. D. & Pascu, S. I., 21 May 2019, In : Nanoscale. 11, 19, p. 9498-9507 10 p.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

NAG-targeting fluorescence based probe for precision diagnosis of kidney injury

Yan, F., Tian, X., Luan, Z., Feng, L., Ma, X. & James, T. D., 7 Feb 2019, In : Chemical communications (Cambridge, England). 55, 13, p. 1955-1958 4 p.

Research output: Contribution to journalArticle

Open Access

Novel 2-arylthiopropanoyl-CoA inhibitors of α-methylacyl-CoA racemase 1A (AMACR; P504S) as potential anti-prostate cancer agents

Jevglevskis, M., Nathubhai, A., Wadda, K., Lee, G. L., Al-Rawi, S., Jiao, T., Mitchell, P., James, T., Threadgill, M., Woodman, T. & Lloyd, M., 7 Sep 2019, In : Bioorganic Chemistry. 92, 103263.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)

Ratiometric fluorescent probe for sensing Streptococcus mutans glucosyltransferase, a key factor in the formation of dental caries

Feng, L., Yan, Q., Zhang, B., Tian, X., Wang, C., Yu, Z., Cui, J., Guo, D., Ma, X. & James, T. D., 25 Mar 2019, In : Chemical Communications. 55, 24, p. 3548-3551 4 p.

Research output: Contribution to journalArticle

Open Access

Target Enzyme-Activated Two-Photon Fluorescent Probes: A Case Study of CYP3A4 Using a Two-Dimensional Design Strategy

Ning, J., Wang, W., Ge, G., Chu, P., Long, F., Yang, Y., Peng, Y., Feng, L., Ma, X. & James, T. D., 17 May 2019, In : Angewandte Chemie - International Edition. 58, 29

Research output: Contribution to journalArticle

The mechanisms of boronate ester formation and fluorescent turn-on in ortho-aminomethylphenylboronic acids

Sun, X., Chapin, B. M., Metola, P., Collins, B., Wang, B., James, T. D. & Anslyn, E. V., 1 Sep 2019, In : Nature Chemistry. 11, 9, p. 768-778 11 p.

Research output: Contribution to journalReview article

1 Citation (Scopus)

Voltammetric characterisation of diferrocenylborinic acid in organic solution and in aqueous media when immobilised into a titanate nanosheet film

Konhefr, M., Sedgwick, A. C., James, T. D., Lacina, K., Skládal, P., Putra, B. R., Harito, C., Bavykin, D. V., Walsh, F. C., Raithby, P. R., Kociok-Köhn, G. & Marken, F., 14 Aug 2019, In : Dalton transactions (Cambridge, England : 2003). 48, 30, p. 11200-11207 8 p.

Research output: Contribution to journalArticle

Open Access
2018
3 Citations (Scopus)
12 Downloads (Pure)

A fluorescent peptidyl substrate for visualizing peptidyl-prolyl cis/trans isomerase activity in live cells

Jiang, Q., Li, X-R., Wang, C-K., Cheng, J., Tan, C., Cui, T-T., Lu, N-N., James, T. D., Han, F. & Li, X., 21 Feb 2018, In : Chemical communications (Cambridge, England). 54, 15, p. 1857-1860 4 p.

Research output: Contribution to journalArticle

Open Access
File
Peptidylprolyl Isomerase
Imaging techniques
Communication
Substrates
Fluorescent Dyes
16 Citations (Scopus)

A hemicyanine based ratiometric fluorescence probe for mapping lysosomal pH during heat stroke in living cells

Wu, L., Wang, Y., James, T. D., Jia, N. & Huang, C., 11 Apr 2018, In : Chemical Communications. 54, p. 5518-5521 4 p.

Research output: Contribution to journalArticle

Open Access
Fluorescence
Cells
Fluorophores
Neurology
Fluorescent Dyes

Analysis of Protein Glycation Using Phenylboronate Acrylamide Gel Electrophoresis

Pereira Morais, M., Munir, O. K., Flower, S., Williams, R. J., James, T. & Van Den Elsen, J., 14 Nov 2018, Electrophoretic Separation of Proteins: Methods and Protocols. T. Kurien, B. & Hal Scofield, R. (eds.). New York, U. S. A.: Humana Press, p. 161-175 (Methods in Molecular Biology; vol. 1855).

Research output: Chapter in Book/Report/Conference proceedingChapter

3 Citations (Scopus)

A naphthoimidazolium-cholesterol derivative as a ratiometric fluorescence based chemosensor for the chiral recognition of carboxylates

Zhang, X., Ko, G., Joung, J. F., Li, M., Jeong, Y., Swamy, K. M. K., Lee, D., Liu, Y., Lee, S., Park, S., James, T. D. & Yoon, J., 22 Nov 2018, In : Chemical communications (Cambridge, England). 54, 94, p. 13264-13267 4 p.

Research output: Contribution to journalArticle

Open Access
7 Citations (Scopus)

'AND'-based fluorescence scaffold for the detection of ROS/RNS and a second analyte

Odyniec, M. L., Sedgwick, A. C., Swan, A. H., Weber, M., Tang, T. M. S., Gardiner, J. E., Zhang, M., Jiang, Y. B., Kociok-Kohn, G., Elmes, R. B. P., Bull, S. D., He, X. P. & James, T. D., 27 Jun 2018, In : Chemical Communications. 54, p. 8466-8469 4 p.

Research output: Contribution to journalArticle

Open Access
Scaffolds
Fluorescence
Biomarkers
Esterases
Fluorescent Dyes
17 Citations (Scopus)

An ESIPT Probe for the Ratiometric Imaging of Peroxynitrite Facilitated by Binding to Aβ-Aggregates

Sedgwick, A. C., Dou, W. T., Jiao, J. B., Wu, L., Williams, G. T., Jenkins, A. T. A., Bull, S. D., Sessler, J. L., He, X. P. & James, T. D., 31 Oct 2018, In : Journal of the American Chemical Society. 140, 43, p. 14267-14271 5 p.

Research output: Contribution to journalArticle

Open Access
19 Citations (Scopus)

A quick and selective rhodamine based “smart probe” for “signal-on” optical detection of Cu2+ and Al3+ in water, cell imaging, computational studies and solid state analysis

Rai, A., Singh, A. K., Tripathi, K., Sonkar, A. K., Chauhan, B. S., Srikrishna, S., James, T. D. & Mishra, L., 1 Aug 2018, In : Sensors and Actuators B: Chemical. 266, p. 95-105

Research output: Contribution to journalArticle

Rhodamines
rhodamine
solid state
Imaging techniques
Water
12 Citations (Scopus)
13 Downloads (Pure)
Open Access
Fructose
Bolts
Boronic Acids
Acids
Fluorescence
3 Citations (Scopus)
12 Downloads (Pure)

A simple umbelliferone based fluorescent probe for the detection of nitroreductase

Sedgwick, A. C., Hayden, A., Hill, B., Bull, S. D., Elmes, R. B. P. & James, T. D., 1 Jun 2018, In : Frontiers of Chemical Science and Engineering. 12, 2, p. 311-314 4 p.

Research output: Contribution to journalArticle

Open Access
File
7-hydroxycoumarin
Nitroreductases
Fluorescent Dyes
Enzymes
Fluorophores
5 Citations (Scopus)
14 Downloads (Pure)

Biodegradable macroporous scaffold with nano-crystal surface microstructure for highly effective osteogenesis and vascularization

Chu, L., Jiang, G., Hu, X., James, T. D., He, X-P., Li, Y. & Tang, T., 21 Mar 2018, In : Journal of Materials Chemistry B . 6, 11, p. 1658-1667

Research output: Contribution to journalArticle

Open Access
File
Scaffolds
Scaffolds (biology)
Crystals
Microstructure
Calcium
6 Citations (Scopus)

Boronate-Based Fluorescence Probes for the Detection of Hydrogen Peroxide

Lampard, E. V., Sedgwick, A. C., Sun, X., Filer, K. L., Hewins, S. C., Kim, G., Yoon, J., Bull, S. D. & James, T. D., 1 Mar 2018, In : ChemistryOpen. 7, 3, p. 262-265

Research output: Contribution to journalArticle

Open Access

Correction: A bodipy based hydroxylamine sensor (Chemical Communications (2017) 53 (10441-10443) DOI: 10.1039/C7CC05872A)

Sedgwick, A. C., Chapman, R. S. L., Gardiner, J. E., Peacock, L. R., Kim, G., Yoon, J., Bull, S. D. & James, T. D., 4 Oct 2018, In : Chemical Communications. 54, 77, p. 10922 1 p.

Research output: Contribution to journalArticle

Open Access

Correction: Boronate based fluorescence (ESIPT) probe for peroxynitrite(Chem. Commun. (2016) 52 (12350–12352) DOI: 10.1039/C6CC06829D)

Sedgwick, A. C., Sun, X., Kim, G., Yoon, J., Bull, S. D. & James, T. D., 28 Sep 2018, In : Chemical Communications. 54, 76, p. 10775 1 p.

Research output: Contribution to journalArticle

Open Access
12 Citations (Scopus)
19 Downloads (Pure)

Dual-function cellulose composites for fluorescence detection and removal of fluoride

Li, M., Liu, Z., Wang, H. C., Sedgwick, A. C., Gardiner, J. E., Bull, S. D., Xiao, H. N. & James, T. D., 1 Feb 2018, In : Dyes and Pigments. 149, p. 669-675 7 p.

Research output: Contribution to journalArticle

Open Access
File
Fluorides
Cellulose
Fluorescence
Adsorption
Composite materials
1 Citation (Scopus)

Dye Displacement Assay for Saccharides using Benzoxaborole Hydrogels

Lampard, E. V., Sedgwick, A. C., Sombuttan, T., Williams, G. T., Wannalerse, B., Jenkins, A. T. A., Bull, S. D. & James, T. D., 1 Mar 2018, In : ChemistryOpen. 7, 3, p. 266-268

Research output: Contribution to journalArticle

Open Access
Hydrogels
Assays
Coloring Agents
Boronic Acids
Monosaccharides
12 Citations (Scopus)

ESIPT-based fluorescence probe for the rapid detection of hypochlorite (HOCl/ClO-)

Wu, L., Yang, Q., Liu, L., Sedgwick, A. C., Cresswell, A. J., Bull, S. D., Huang, C. & James, T. D., 4 Jul 2018, In : Chemical Communications. 54, 61, p. 8522-8525 4 p.

Research output: Contribution to journalArticle

Open Access
Hypochlorous Acid
Fluorescence
Water
Logic gates
Potable water
8 Citations (Scopus)

ESIPT-based fluorescence probe for the rapid detection of peroxynitrite ‘AND' biological thiols

Wu, L., Han, H. H., Liu, L., Gardiner, J. E., Sedgwick, A. C., Huang, C., Bull, S. D., He, X. P. & James, T. D., 14 Oct 2018, In : Chemical Communications. 54, 80, p. 11336-11339 4 p.

Research output: Contribution to journalArticle

Open Access
12 Citations (Scopus)

ESIPT-based ratiometric fluorescence probe for the intracellular imaging of peroxynitrite

Wu, L., Wang, Y., Weber, M., Liu, L., Sedgwick, A. C., Bull, S. D., Huang, C. & James, T. D., 7 Aug 2018, In : Chemical Communications. 54, 71, p. 9953-9956 4 p.

Research output: Contribution to journalArticle

Open Access
Peroxynitrous Acid
Fluorescent Dyes
Fluorescence
Imaging techniques
Experiments
45 Citations (Scopus)

Excited-state intramolecular proton-transfer (ESIPT) based fluorescence sensors and imaging agents

Sedgwick, A. C., Wu, L., Han, H. H., Bull, S. D., He, X. P., James, T. D., Sessler, J. L., Tang, B. Z., Tian, H. & Yoon, J., 26 Nov 2018, In : Chemical Society Reviews. 47, 23, p. 8842-8880 39 p.

Research output: Contribution to journalReview article

Open Access
6 Citations (Scopus)
21 Downloads (Pure)
Open Access
File
Peroxynitrous Acid
Macrophages
Reactive Oxygen Species
Fluorescence
Oxidative stress
14 Citations (Scopus)

Fluorescence detection and removal of copper from water using a biobased and biodegradable 2D soft material

Li, M., Liu, Z., Wang, S., Calatayud, D. G., Zhu, W. H., James, T. D., Wang, L., Mao, B. & Xiao, H. N., 7 Jan 2018, In : Chemical Communications. 54, 2, p. 184-187 4 p.

Research output: Contribution to journalArticle

Open Access
Metal ions
Copper
Fluorescence
Graphite
Water
14 Citations (Scopus)

Long-wavelength TCF-based fluorescence probes for the detection and intracellular imaging of biological thiols

Sedgwick, A. C., Gardiner, J. E., Kim, G., Yevglevskis, M., Lloyd, M. D., Jenkins, A. T. A., Bull, S. D., Yoon, J. & James, T. D., 2018, In : Chemical Communications. 54, 38, p. 4786-4789 4 p.

Research output: Contribution to journalArticle

Open Access
Sulfhydryl Compounds
Toxicity
Fluorescence
Drug therapy
Imaging techniques
72 Citations (Scopus)

Molecular logic gates: the past, present and future

Erbas-cakmak, S., Kolemen, S., Sedgwick, A. C., Gunnlaugsson, T., James, T. D., Yoon, J. & Akkaya, E. U., 1 Mar 2018, In : Chemical Society Reviews. 47, 7, p. 2228-2248 21 p.

Research output: Contribution to journalReview article

Open Access
Logic gates
Silicon
Integrated circuits
Tissue
Molecules
1 Citation (Scopus)
5 Downloads (Pure)

Osteogenesis, vascularization and osseointegration of a bioactive multiphase macroporous scaffold in the treatment of large bone defects

Chu, L., Jiang, G., Hu, X., James, T. D., He, X-P., Li, Y. & Tang, T., 2018, In : Journal of Materials Chemistry B . 6, 25, p. 4197-4204 10 p.

Research output: Contribution to journalArticle

Open Access
File
Scaffolds
Bone
Defects
Bone Substitutes
Biocompatible Materials

Preferential colonization of osteoblasts over co-cultured bacteria on a bifunctional biomaterial surface

Chu, L., Yang, Y., Yang, S., Fan, Q., Yu, Z., Hu, X. L., James, T. D., He, X. P. & Tang, T., 2 Oct 2018, In : Frontiers in Microbiology. 9, OCT, 2219.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

Proline-Based Boronic Acid Receptors for Chiral Recognition of Glucose

Guo, L-E., Hong, Y., Zhang, S-Y., Zhang, M., Yan, X-S., Cao, J-L., Li, Z., James, T. D. & Jiang, Y-B., 22 Nov 2018, In : Journal of Organic Chemistry. 8 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Promoting magnesium sulfite oxidation: Via partly oxidized metal nanoparticles on graphitic carbon nitride (g-C3N4) in the magnesia desulfurization process

Li, M., Qi, T., Yang, R., Xiao, H. N., Fang, Z., Hodge, S. A., James, T. D., Wang, L. & Mao, B., 28 Jun 2018, In : Journal of Materials Chemistry A. 6, 24, p. 11296-11305 10 p.

Research output: Contribution to journalArticle

Magnesium Oxide
Sulfites
Carbon nitride
Metal nanoparticles
Magnesia
1 Citation (Scopus)

Selective Cu2+ Ion Sensing by Nanoaggregates of Pyridyl-2,6-bis(3-allylsalicylaldehyde)hydrazone

Rai, A., Tripathi, K., Kumar Sonkar, A., James, T. D., Yashaswee, S., Kumar Trigun, S. & Mishra, L., 24 May 2018, In : ChemistrySelect. 3, 19, p. 5395-5400 6 p.

Research output: Contribution to journalArticle

Hydrazones
Ions
Cells
Water