Tony James

Prof, Royal Society Wolfson Research Merit Award Holder, Fellow of the Royal Society of Chemistry

  • 1 SOUTH 0.21

Accepting PhD Students

1987 …2022
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Research Output 1987 2018

2018

A fluorescent peptidyl substrate for visualizing peptidyl-prolyl cis/trans isomerase activity in live cells

Jiang, Q., Li, X-R., Wang, C-K., Cheng, J., Tan, C., Cui, T-T., Lu, N-N., James, T. D., Han, F. & Li, X. 21 Feb 2018 In : Chemical communications (Cambridge, England). 54, 15, p. 1857-1860 4 p.

Research output: Contribution to journalArticle

Peptidylprolyl Isomerase
Imaging techniques
Communication
Substrates
Fluorescent Dyes

A hemicyanine based ratiometric fluorescence probe for mapping lysosomal pH during heat stroke in living cells

Wu, L., Wang, Y., James, T. D., Jia, N. & Huang, C. 11 Apr 2018 In : Chemical Communications. 54, p. 5518-5521 4 p.

Research output: Contribution to journalArticle

Open Access
Fluorescence
Cells
Fluorophores
Neurology
Fluorescent Dyes

A quick and selective rhodamine based “smart probe” for “signal-on” optical detection of Cu2+ and Al3+ in water, cell imaging, computational studies and solid state analysis

Rai, A., Singh, A. K., Tripathi, K., Sonkar, A. K., Chauhan, B. S., Srikrishna, S., James, T. D. & Mishra, L. 5 Feb 2018 In : Sensors and Actuators B: Chemical. 266, p. 95-105

Research output: Contribution to journalArticle

Rhodamines
rhodamine
solid state
Imaging techniques
Water
1 Citations
Open Access
File
Fructose
Bolts
Boronic Acids
Acids
Fluorescence

A simple umbelliferone based fluorescent probe for the detection of nitroreductase

Sedgwick, A. C., Hayden, A., Hill, B., Bull, S. D., Elmes, R. B. P. & James, T. D. 17 Jan 2018 In : Frontiers of Chemical Science and Engineering. p. 1-4 4 p.

Research output: Contribution to journalArticle

7-hydroxycoumarin
Nitroreductases
Fluorescent Dyes
Enzymes
Fluorophores

Biodegradable macroporous scaffold with nano-crystal surface microstructure for highly effective osteogenesis and vascularization

Chu, L., Jiang, G., Hu, X., James, T. D., He, X-P., Li, Y. & Tang, T. 21 Mar 2018 In : Journal of Materials Chemistry B . 6, 11, p. 1658-1667

Research output: Contribution to journalArticle

Scaffolds
Scaffolds (biology)
Crystals
Microstructure
Calcium

Boronate-Based Fluorescence Probes for the Detection of Hydrogen Peroxide

Lampard, E. V., Sedgwick, A. C., Sun, X., Filer, K. L., Hewins, S. C., Kim, G., Yoon, J., Bull, S. D. & James, T. D. 1 Mar 2018 In : ChemistryOpen. 7, 3, p. 262-265

Research output: Contribution to journalArticle

Open Access
1 Citations

Dual-function cellulose composites for fluorescence detection and removal of fluoride

Li, M., Liu, Z., Wang, H. C., Sedgwick, A. C., Gardiner, J. E., Bull, S. D., Xiao, H. N. & James, T. D. 1 Feb 2018 In : Dyes and Pigments. 149, p. 669-675 7 p.

Research output: Contribution to journalArticle

Fluorides
Cellulose
Fluorescence
Adsorption
Composite materials

Dye Displacement Assay for Saccharides using Benzoxaborole Hydrogels

Lampard, E. V., Sedgwick, A. C., Sombuttan, T., Williams, G. T., Wannalerse, B., Jenkins, A. T. A., Bull, S. D. & James, T. D. 1 Mar 2018 In : ChemistryOpen. 7, 3, p. 266-268

Research output: Contribution to journalArticle

Open Access
Hydrogels
Assays
Coloring Agents
Boronic Acids
Monosaccharides
2 Citations

Fluorescence detection and removal of copper from water using a biobased and biodegradable 2D soft material

Li, M., Liu, Z., Wang, S., Calatayud, D. G., Zhu, W. H., James, T. D., Wang, L., Mao, B. & Xiao, H. N. 7 Jan 2018 In : Chemical Communications. 54, 2, p. 184-187 4 p.

Research output: Contribution to journalArticle

Open Access
Metal ions
Copper
Fluorescence
Graphite
Water
Open Access
Sulfhydryl Compounds
Toxicity
Fluorescence
Drug therapy
Imaging techniques
2 Citations

Molecular logic gates: the past, present and future

Erbas-cakmak, S., Kolemen, S., Sedgwick, A. C., Gunnlaugsson, T., James, T. D., Yoon, J. & Akkaya, E. U. 1 Mar 2018 In : Chemical Society Reviews. 47, 7, p. 2228-2248 21 p.

Research output: Contribution to journalArticle

Open Access
Logic gates
Silicon
Integrated circuits
Tissue
Molecules

Osteogenesis, vascularization and osseointegration of a bioactive multiphase macroporous scaffold in the treatment of large bone defects

Chu, L., Jiang, G., Hu, X., James, T. D., He, X., Li, Y. & Tang, T. 2018 In : Journal of Materials Chemistry B . 10 p.

Research output: Contribution to journalArticle

Scaffolds
Bone
Defects
Bone Substitutes
Biocompatible Materials

Structure-activity relationships of rationally designed AMACR 1A inhibitors

Jevglevskis, M., Lee, G. L., Nathubhai, A., Petrova, Y., James, T., Threadgill, M., Woodman, T. & Lloyd, M. 30 Apr 2018 In : Bioorganic and Medicinal Chemistry. 79, p. 145-154 10 p.

Research output: Contribution to journalArticle

Acyl Coenzyme A
Enzyme activity
Coenzyme A
Assays
Esters

Supramolecular glyco-poly-cyclodextrin functionalized 2D probe for targeted stimulus-responsive bioimaging

Wang, H., Liu, Y., Xu, C., Wang, X., Chen, G-R., James, T. D., Zang, Y., Li, J., Ma, X. & He, X-P. 18 Apr 2018 In : Chemical Communications. 54, 32, p. 4037-4040

Research output: Contribution to journalArticle

Cyclodextrins
Cells
1 Citations

The development of a novel AND logic based fluorescence probe for the detection of peroxynitrite and GSH

Sedgwick, A. C., Han, H. H., Gardiner, J. E., Bull, S. D., He, X-P. & James, T. D. 21 Apr 2018 In : Chemical Science. 9, 15, p. 3672-3676

Research output: Contribution to journalArticle

Open Access
Peroxynitrous Acid
Fluorescence
Fluorescein
Imaging techniques
Experiments

Virtual Issue: Chemosensors

Sedgwick, A. C. & James, T. D. 1 Mar 2018 In : ChemistryOpen. 7, 3, p. 215-216 2 p.

Research output: Contribution to journalSpecial issue

Open Access
Fluorescence
Molecular interactions
Public health
Agriculture
Imaging techniques
2017
1 Citations

A 1-hydroxy-2,3,1-benzodiazaborine-containing π-conjugated system: synthesis, optical properties and solvent-dependent response toward anions

Satta, Y., Nishiyabu, R., James, T. D. & Kubo, Y. 13 Apr 2017 In : Tetrahedron. 73, 15, p. 2053-2061 9 p.

Research output: Contribution to journalArticle

File
Optical Devices
Dimethyl Sulfoxide
Anions
Boron
Optical properties
3 Citations

A bodipy based hydroxylamine sensor

Sedgwick, A. C., Chapman, R. S. L., Gardiner, J. E., Peacock, L. R., Kim, G., Yoon, J., Bull, S. D. & James, T. D. 25 Sep 2017 In : Chemical Communications. 53, 75, p. 10441-10443

Research output: Contribution to journalArticle

Open Access
Hydroxylamine
Fluorescence
Sensors

A convenient colorimetric assay for α-methylacyl-CoA racemase (AMACR; P504S) and testing of inhibitors

Jevglevskis, M., Lee, G. L., Nathubhai, A., James, T., Threadgill, M., Woodman, T. & Lloyd, M. 21 Apr 2017 (Unpublished)

Research output: Contribution to conferenceAbstract

File
Coenzyme A
Inhibitory Concentration 50
Acyl Coenzyme A
Prostatic Neoplasms
S 10
7 Citations

A fluorogenic 2D glycosheet for the simultaneous identification of human-and avian-receptor specificity in influenza viruses

Song, J. X., Tang, X. Y., Zhou, D. M., Zhang, W., James, T. D., He, X-P. & Tian, H. 7 Mar 2017 In : Materials Horizons. 4, 3, p. 431-436 6 p.

Research output: Contribution to journalArticle

Open Access
Viruses
Polysaccharides
Color
Fluorophores
Switches
2 Citations

A novel colorimetric assay for α-methylacyl-CoA racemase 1A (AMACR; P504S) utilizing the elimination of 2,4-dinitrophenolate

Jevglevskis, M., Lee, G. L., Nathubhai, A., Petrova, Y., James, T., Threadgill, M., Woodman, T. & Lloyd, M. 7 May 2017 In : Chemical Communications. 53, 37, p. 5087-5090 4 p.

Research output: Contribution to journalArticle

Open Access
Assays
Ibuprofen
Fatty acids
Fatty Acids
Degradation
5 Citations

Azulene–boronate esters: colorimetric indicators for fluoride in drinking water

Lopez-Alled, C. M., Sanchez Fernandez, A., Edler, K., Sedgwick, A., Bull, S., McMullin, C., Kociok-Kohn, G., James, T., Wenk, J. & Lewis, S. 4 Dec 2017 In : Chemical Communications. 53, 93, p. 12580-12583 4 p.

Research output: Contribution to journalArticle

Open Access
Fluorides
Developing countries
Potable water
Drinking Water
Esters
2 Citations

Behavior of Supramolecular Assemblies of Radiometal-Filled and Fluorescent Carbon Nanocapsules In Vitro and In Vivo

Ge, H., Riss, P. J., Mirabello, V., Calatayud, D. G., Flower, S. E., Arrowsmith, R. L., Fryer, T. D., Hong, Y., Sawiak, S., Jacobs, R. M. J., Botchway, S. W., Tyrrell, R. M., James, T. D., Fossey, J. S., Dilworth, J. R., Aigbirhio, F. I. & Pascu, S. I. 14 Sep 2017 In : Chem. 3, 3, p. 437-460

Research output: Contribution to journalArticle

Open Access
File
Nanocapsules
Carbon Nanotubes
beta-Glucans
Carbon
Optical Imaging

Benzoxaboroles and Boronic Acids for Sensing Applications

Lampard, E. Sep 2017

Research output: ThesisDoctoral Thesis

Open Access
File
Boronic Acids
Sugars
Hydrogels
Esters
Hydrogen Peroxide
2 Citations

Boronic Acid Mediated Coupling of Catechols and N-Hydroxylamines: A Bioorthogonal Reaction to Label Peptides

Meadows, M. K., Roesner, E. K., Lynch, V. M., James, T. D. & Anslyn, E. V. 16 Jun 2017 In : Organic Letters. 19, 12, p. 3179-3182 4 p.

Research output: Contribution to journalArticle

Open Access
File
Hydroxylamines
Catechols
Boronic Acids
peptides
Labels

Carbohydrate Directed Photoaffinity Labelling

Fowle, C. Sep 2017 136 p.

Research output: ThesisDoctoral Thesis

Open Access
File
Labeling
Carbohydrates
Biological systems
Caseins
Proteins

Electroanalysis in 2D-TiO2 Nanosheet Hosts: Electrolyte and Selectivity Effects in Ferroceneboronic Acid – Saccharide Binding

Tri Wahyuni, W., Marken, F., Putra, B. R., Bavykin, D. V., Walsh, F. C., James, T., Kociok-Kohn, G. & Harito, C. 17 Nov 2017 In : Electroanalysis.

Research output: Contribution to journalArticle

Nanosheets
Electrolytes
Fructose
Acids
Glucose
18 Citations

Fluorescent glycoprobes: a sweet addition for improved sensing

He, X. P., Zang, Y., James, T. D., Li, J., Chen, G. R. & Xie, J. 4 Jan 2017 In : Chemical Communications. 53, 1, p. 82-90 9 p.

Research output: Contribution to journalArticle

Open Access
Fluorescent Dyes
Solubility
Ions
Imaging techniques
Water
2 Citations

Graphene oxide-enhanced cytoskeleton imaging and mitosis tracking

Li, Q. R., Jiao, J. B., Li, L. L., He, X. P., Zang, Y., James, T. D., Chen, G. R., Guo, L. & Li, J. 28 Feb 2017 In : Chemical Communications. 53, 23, p. 3373-3376 4 p.

Research output: Contribution to journalArticle

Open Access
Graphite
Oxides
Graphene
Peptides
Imaging techniques
1 Citations

High-Throughput Assay for Enantiomeric Excess Determination in 1,2- and 1,3-Diols and Direct Asymmetric Reaction Screening

Shcherbakova, E. G., Brega, V., Lynch, V. M., James, T. D. & Anzenbacher, P. 26 Jul 2017 In : Chemistry - A European Journal. 23, 42, p. 10222-10229 8 p.

Research output: Contribution to journalArticle

Open Access
File
Assays
Screening
Throughput
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Self assembly
Photochromism
Fluorescent Dyes
Imaging techniques
Biological systems
Fluorescence
8 Citations

Long-wavelength fluorescent boronate probes for the detection and intracellular imaging of peroxynitrite

Sedgwick, A. C., Han, H. H., Gardiner, J. E., Bull, S. D., He, X-P. & James, T. D. 11 Dec 2017 In : Chemical Communications. 53, 95, p. 12822-12825

Research output: Contribution to journalArticle

Open Access
Mitochondria
Peroxynitrous Acid
Solubility
Imaging techniques
Wavelength
5 Citations

Lysosomal tracking with a cationic naphthalimide using multiphoton fluorescence lifetime imaging microscopy

Li, M., Ge, H., Mirabello, V., Arrowsmith, R. L., Kociok-Kohn, G., Botchway, S. W., Zhu, W., Pascu, S. I. & James, T. D. 18 Oct 2017 In : Chemical Communications. 53, 81, p. 11161-11164

Research output: Contribution to journalArticle

Open Access
File
Naphthalimides
Microscopic examination
Fluorescence
Imaging techniques
Protonation
6 Citations

Macrophage Migration Inhibitory Factor is subjected to glucose modification and oxidation in Alzheimer's Disease

Kassaar, O., Pereira Morais, M., Xu, S., Adam, E. L., Chamberlain, R. C., Jenkins, B., James, T., Francis, P. T., Ward, S., Williams, R. J. & Van Den Elsen, J. 23 Feb 2017 In : Scientific Reports. 7, 42874

Research output: Contribution to journalArticle

Open Access
Macrophage Migration-Inhibitory Factors
Alzheimer Disease
Glucose
Hyperglycemia
Aptitude
5 Citations

Photochromism and molecular logic gate operation of a water-compatible bis-glycosyl diarylethene

Chai, X., Fu, Y. X., James, T. D., Zhang, J., He, X-P. & Tian, H. 1 Aug 2017 In : Chemical Communications. 53, 68, p. 9494-9497 4 p.

Research output: Contribution to journalArticle

Open Access
Photochromism
Logic gates
Water
4 Citations

Rapid determination of enantiomeric excess via NMR spectroscopy: A research-informed experiment

Fossey, J. S., Anslyn, E. V., Brittain, W. D. G., Bull, S. D., Chapin, B. M., Le Duff, C. S., James, T. D., Lees, G., Lim, S., Lloyd, J. A. C., Manville, C. V., Payne, D. T. & Roper, K. A. 10 Jan 2017 In : Journal of Chemical Education. 94, 1, p. 79-84 6 p.

Research output: Contribution to journalArticle

Open Access
Nuclear magnetic resonance spectroscopy
experiment
Experiments
Teaching
chemistry
4 Citations

Reaction-based indicator displacement assay (RIA) for the colorimetric and fluorometric detection of hydrogen peroxide

Sun, X., Odyniec, M. L., Sedgwick, A. C., Lacina, K., Xu, S., Qiang, T., Bull, S. D., Marken, F. & James, T. D. 1 Jun 2017 In : Organic Chemistry Frontiers. 4, 6, p. 1058-1062 5 p.

Research output: Contribution to journalArticle

Open Access
Hydrogen Peroxide
Assays
Phenol
Complexation
Fluorescence
1 Citations

Supramolecular core-glycoshell polythiophene nanodots for targeted imaging and photodynamic therapy

Han, H. H., Wang, C. Z., Zang, Y., Li, J., James, T. D. & He, X-P. 2017 In : Chemical Communications. 53, 70, p. 9793-9796 4 p.

Research output: Contribution to journalArticle

Open Access
Photodynamic therapy
Liver
Optoelectronic devices
Self assembly
Cells
6 Citations

Supramolecular polymer dot ensemble for ratiometric detection of lectins and targeted delivery of imaging agents

Wang, C. Z., Chen, J. L., Tang, Y., Zang, Y., Chen, G. R., James, T. D., Li, J., Wu, C. & He, X. P. 1 Feb 2017 In : ACS Applied Materials and Interfaces. 9, 4, p. 3272-3276 5 p.

Research output: Contribution to journalArticle

Open Access
File
Lectins
Polymers
Imaging techniques
Cell membranes
Sugars

Synthesis of Novel Diagnostic systems

Sedgwick, A. Nov 2017

Research output: ThesisDoctoral Thesis

Open Access
File
Fluorescent Dyes
Peroxynitrous Acid
Phenol
Imaging techniques
Boronic Acids
2 Citations

Targeted tumor detection: guidelines for developing biotinylated diagnostics

Jang, J. H., Kim, W. R., Sharma, A., Cho, S. H., James, T. D., Kang, C. & Kim, J. S. 14 Feb 2017 In : Chemical Communications. 53, 13, p. 2154-2157 4 p.

Research output: Contribution to journalArticle

Open Access
File
Hydrophilicity
Fluorescent Dyes
Medicine
Tumors
2016

A convenient colorimetric assay for alpha-methylacyl-CoA racemase (AMACR; P504S) and testing for inhibitors

Jevglevskis, M., Lee, G. L., Nathubhai, A., James, T., Threadgill, M., Woodman, T. & Lloyd, M. 21 May 2016 (Unpublished)

Research output: Contribution to conferencePoster

File

A Convenient Colorimetric Assay For Alpha-Methylacyl-CoA Racemase (AMACR; P504S) And Testing Of Inhibitors

Jevglevskis, M., Lee, G. L., Nathubhai, A., Petrova, Y., Threadgill, M., James, T., Woodman, T. & Lloyd, M. Jun 2016

Research output: Contribution to conferencePoster

Open Access
File

A Convenient Colorimetric Assay for α-Methylacyl-CoA Racemase (AMACR; P504S) and Testing Of Inhibitors

Jevglevskis, M., Lee, G. L., Nathubhai, A., James, T., Threadgill, M., Woodman, T. & Lloyd, M. 27 Apr 2016 (Unpublished)

Research output: Contribution to conferencePoster

File
24 Citations

A fluorescent chemodosimeter for live-cell monitoring of aqueous sulfides

Wang, S., Xu, S., Hu, G., Bai, X., James, T. D. & Wang, L. 19 Jan 2016 In : Analytical Chemistry. 88, 2, p. 1434-1439 6 p.

Research output: Contribution to journalArticle

Sulfides
Monitoring
Fluorescence
Sulfur Compounds
Fluorescent Dyes
1 Citations
Open Access
File
Spectroscopic analysis
Esters
Nuclear magnetic resonance
Acids
5 Citations

A study on the AMACR catalysed elimination reaction and its application to inhibitor testing

Jevglevskis, M., Lee, G. L., Sun, J., Zhou, S., Sun, X., Kociok-Kohn, G., James, T. D., Woodman, T. J. & Lloyd, M. D. Jan 2016 In : Organic and Biomolecular Chemistry. 14, 2, p. 612-622

Research output: Contribution to journalArticle

Open Access
File
inhibitors
elimination
Acyl Coenzyme A
Coenzyme A
Assays

A Study On The α-Methylacyl-CoA Racemase (AMACR) Elimination Reaction And Its Application To Inhibitor Testing

Jevglevskis, M., Lee, G. L., Sun, J., Zhou, S., Sun, X., Kociok-Kohn, G., James, T., Woodman, T. & Lloyd, M. 27 Apr 2016 (Unpublished)

Research output: Contribution to conferencePoster

File