Projects per year
Personal profile
Research interests
I’m a computational evolutionary biologist interested in the history of life and the processes of evolution. I mainly work on questions about the “tree of life”, evolution in deep time, and the evolution of (usually microbial) genomes, from the perspectives of phylogenetics, comparative genomics and bioinformatics. Some of the questions I work on include:
- The structure of the tree of life, and the phylogenetic position of eukaryotic cells - for example, are there two or three primary domains?
- The origin of eukaryotes, including our archaeal and bacterial ancestry, the stages of endosymbiotic integration, and the subsequent evolution of eukaryotic lineages.
- The nature (metabolism, physiology, cell biology) of early life forms, including LUCA (the common ancestor of all life), the early members of the archaeal and bacterial domains, and the diversity of single-celled eukaryotes.
- The course of metabolic evolution - what are the oldest metabolic pathways, and how have life and the “Earth system” co-evolved through time?
- Co-evolutionary relationships among microbes and between microbes and their hosts, including symbiosis and endosymbiosis.
- Phylogenetics and bioinformatics methods development, for making sense of today’s large-scale biological (e.g. omics) datasets.
Lab website here: https://tancata.github.io
Current group members
- Dr. Giorgio Bianchini (evolution of symbiotic integration, the origin of eukaryotes)
- Dr. Zoe Vance (whole genome duplication - with James Clark and the WGDip consortium)
- Chenxue Lin (early eukaryote evolution)
- Lijia Jiang (evolution of archaeal metabolisms)
Get in touch if you are interested in joining - currently hiring for PDRA and PhD positions at Bath.
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Collaborations and top research areas from the last five years
Projects
- 2 Active
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Microbial mercury methylation: a detoxifying defence or an antimicrobial advantage?
Williams, T. (PI)
1/09/25 → 31/08/28
Project: Research council
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Reappraising the role of whole genome duplication and rediploidization in eukaryotic evolution
Clark, J. (PI) & Williams, T. (CoI)
1/04/25 → 31/03/29
Project: Research council
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Ancestral gene content estimates under gain–loss–duplication depend on the chosen observation threshold
Szollosi, G. J. & Williams, T., 4 Aug 2026, In: Proceedings of the National Academy of Sciences of the United States of America. 123, 31, p. e2618431123 2 p., e2618431123.Research output: Contribution to journal › Letter › peer-review
Open Access1 Link opens in a new tab Citation (SciVal) -
Horizontal gene transfer and gene loss drove the divergent evolution of host dependency in Micrarchaeota
Rao, Y.-Z., Li, Y.-X., Li, Z.-W., Qu, Y.-N., Hedlund, B. P., Williams, T., Qi, Y.-L., Xie, Q.-J., Yang, H.-L., Zhang, Y.-Q., Jiang, H.-C., Palmer, M., Shi, M., Shu, W.-S., Hua, Z.-S. & Li, W.-J., 28 Feb 2026, In: National Science Review. 13, 4, nwaf542.Research output: Contribution to journal › Article › peer-review
Open Access3 Link opens in a new tab Citations (SciVal) -
New lineages provide insights into the convergent evolution of extreme salt adaptation within symbiotic Archaea
Hamm, J. N., Dombrowski, N., Valentin-Alvarado, L. E., Greening, C., Williams, T. A. & Spang, A., 31 May 2026, In: Molecular Biology and Evolution. 43, 5, 14 p., MBE-25-0854.Research output: Contribution to journal › Article › peer-review
Open Access1 Link opens in a new tab Citation (SciVal) -
The prokaryotic origins of the COMMD protein family involved in eukaryotic membrane trafficking
Lu, M., Moody, E. R. R., Blades, F., Puente-Lelievre, C., Chen, K.-E., Stephens, E. J., Michie, K. A., Cater, R. J., Williams, T. A., Collins, B. M. & Healy, M. D., 29 May 2026, In: Nature Communications. 17, 1, 15 p., 6989.Research output: Contribution to journal › Article › peer-review
Open Access -
Vertical stratification and metabolic versatility of methanogens in Haima cold seep sediments: Alkane-fueled acetoclastic methanogenesis revealed by metagenomics and experimental verification
Jiang, L., Liang, Z., Williams, T., Deng, Y., Yu, H., Hao, Q., Cao, J., Zhou, H., Lai, H., Chen, J., Chen, H. & Zhang, C., 1 May 2026, In: Marine Environmental Research. 217, 12 p., 107972.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Link opens in a new tab Citation (SciVal)17 Downloads (Pure)