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20092019
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Research Output 2009 2019

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Article
2019

Acute effects of cannabinoids on addiction endophenotypes are moderated by genes encoding the CB1 receptor and FAAH enzyme

Hindocha, C., Freeman, T. P., Schafer, G., Gardner, C., Bloomfield, M. A. P., Bramon, E., Morgan, C. J. A. & Curran, H. V., 23 Apr 2019, In : Addiction Biology. e12762.

Research output: Contribution to journalArticle

Dissociable effects of cannabis with and without cannabidiol on the human brain’s resting-state functional connectivity

Wall, M. B., Pope, R., Freeman, T. P., Kowalczyk, O. S., Demetriou, L., Mokrysz, C., Hindocha, C., Lawn, W., Bloomfield, M. A. P., Freeman, A. M., Feilding, A., Nutt, D. J. & Curran, H. V., 1 Jul 2019, In : Journal of Psychopharmacology. 33, 7, p. 822-830 9 p.

Research output: Contribution to journalArticle

Open Access
File
3 Citations (Scopus)

Increasing potency and price of cannabis in Europe, 2006-16

Freeman, T. P., Groshkova, T., Cunningham, A., Sedefov, R., Griffiths, P. & Lynskey, M. T., 1 Jun 2019, In : Addiction. 114, 6, p. 1015-1023

Research output: Contribution to journalArticle

Open Access

Medicinal use of cannabis based products and cannabinoids

Freeman, T. P., Hindocha, C., Green, S. F. & Bloomfield, M. A. P., 4 Apr 2019, In : British Medical Journal. 365, 7 p., l1141.

Research output: Contribution to journalArticle

Open Access
5 Citations (Scopus)

New trends in cannabis potency in USA and Europe during the last decade (2008-2017)

Chandra, S., Radwan, M. M., Majumdar, C. G., Church, J. C., Freeman, T. P. & ElSohly, M. A., 1 Feb 2019, In : European Archives of Psychiatry and Clinical Neuroscience. 269, 1, p. 5-15 11 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

The contribution of cannabis use to variation in the incidence of psychotic disorder across Europe (EU-GEI): a multicentre case-control study

Di Forti, M., Quattrone, D., Freeman, T., Tripoli, G., Gayer-Anderson, C., Quigley, H., Rodriguez, V., Jongsma, H. E., Ferraro, L., La Cascia, C., La Barbera, D., Tarricone, I., Berardi, D., Szoke, A., Arango, C., Tortelli, A., Velthorst, E., Bernardo, M., Del-Ben, C. M., Menezes, P. R. & 3 othersSelten, J-P., Jones, P. B. & Kirkbride, J. B., 1 May 2019, In : The Lancet Psychiatry. 6, 5, p. 427-436 10 p.

Research output: Contribution to journalArticle

Open Access
2018
6 Citations (Scopus)

Cannabidiol reverses attentional bias to cigarette cues in a human experimental model of tobacco withdrawal

Hindocha, C., Freeman, T. P., Grabski, M., Stroud, J. B., Crudgington, H., Davies, A. C., Das, R. K., Lawn, W., Morgan, C. J. A. & Curran, H. V., 2 Aug 2018, In : Addiction. 113, 9, p. 1696-1705 10 p.

Research output: Contribution to journalArticle

Open Access
Cannabidiol
Tobacco Products
Tobacco
Cues
Theoretical Models
3 Citations (Scopus)

Cannabis Dampens the Effects of Music in Brain Regions Sensitive to Reward and Emotion

Freeman, T. P., Pope, R. A., Wall, M. B., Bisby, J. A., Luijten, M., Hindocha, C., Mokrysz, C., Lawn, W., Moss, A., Bloomfield, M. A. P., Morgan, C. J. A., Nutt, D. J. & Curran, H. V., 1 Jan 2018, In : International Journal of Neuropsychopharmacology. 21, 1, p. 21-32 12 p.

Research output: Contribution to journalArticle

Open Access
Cannabis
Music
Reward
Emotions
Cannabidiol
17 Citations (Scopus)

Changes in cannabis potency and first-time admissions to drug treatment: a 16-year study in the Netherlands

Freeman, T. P., van der Pol, P., Kuijpers, W., Wisselink, J., Das, R. K., Rigter, S., van Laar, M., Griffiths, P., Swift, W., Niesink, R. & Lynskey, M. T., 31 Oct 2018, In : Psychological Medicine. 48, 14, p. 2346-2352 7 p.

Research output: Contribution to journalArticle

Open Access
File
Cannabis
Netherlands
Dronabinol
Pharmaceutical Preparations
Linear Models
5 Citations (Scopus)

Individual and combined effects of acute delta-9-tetrahydrocannabinol and cannabidiol on psychotomimetic symptoms and memory function

Morgan, C. J. A., Freeman, T. P., Hindocha, C., Schafer, G., Gardner, C. & Curran, H. V., 5 Sep 2018, In : Translational Psychiatry. 8, 1, 10 p., 181.

Research output: Contribution to journalArticle

Open Access
Cannabidiol
Dronabinol
Cannabis
Episodic Memory
Short-Term Memory
5 Citations (Scopus)

Psilocybin with psychological support improves emotional face recognition in treatment-resistant depression

Stroud, J. B., Freeman, T. P., Leech, R., Hindocha, C., Lawn, W., Nutt, D. J., Curran, H. V. & Carhart-Harris, R. L., Feb 2018, In : Psychopharmacology. 235, 2, p. 459-466 8 p.

Research output: Contribution to journalArticle

Open Access
Psilocybin
Treatment-Resistant Depressive Disorder
Psychology
Anhedonia
Emotions
1 Citation (Scopus)

Restrictions on drugs with medical value: Moving beyond stalemate

Freeman, T. P., Mehta, M. A., Neill, J. C., Nutt, D. J., Tunbridge, E. M. & Young, A. H., Oct 2018, In : Journal of Psychopharmacology . 32, 10, p. 1053-1055 3 p.

Research output: Contribution to journalArticle

Open Access
File
3 Citations (Scopus)

The Acute Effects of a Dopamine D3 Receptor Preferring Agonist on Motivation for Cigarettes in Dependent and Occasional Cigarette Smokers

Lawn, W., Freeman, T. P., East, K., Gaule, A., Aston, E. R., Bloomfield, M. A. P., Das, R. K., Morgan, C. J. A. & Curran, H. V., 7 Jun 2018, In : Nicotine & Tobacco Research. 20, 7, p. 800-809 10 p.

Research output: Contribution to journalArticle

Open Access
Dopamine D3 Receptors
Tobacco Products
Motivation
Reward
Tobacco Use Disorder
2 Citations (Scopus)

The effects of cannabidiol on impulsivity and memory during abstinence in cigarette dependent smokers

Hindocha, C., Freeman, T. P., Grabski, M., Crudgington, H., Davies, A. C., Stroud, J. B., Das, R. K., Lawn, W., Morgan, C. J. A. & Curran, H. V., 1 Dec 2018, In : Scientific Reports. 8, 1, 7568.

Research output: Contribution to journalArticle

Open Access
Cannabidiol
Impulsive Behavior
Tobacco Products
Nicotine
Short-Term Memory
6 Citations (Scopus)

Which biological and self-report measures of cannabis use predict cannabis dependency and acute psychotic-like effects?

Curran, H. V., Hindocha, C., Morgan, C. J. A., Shaban, N., Das, R. K. & Freeman, T. P., 4 Sep 2018, In : Psychological Medicine. p. 1-7 7 p.

Research output: Contribution to journalArticle

Open Access
Cannabis
Self Report
Dronabinol
Cannabidiol
Cannabinol
2017
14 Citations (Scopus)

Acute memory and psychotomimetic effects of cannabis and tobacco both 'joint' and individually: a placebo-controlled trial

Hindocha, C., Freeman, T. P., Xia, J. X., Shaban, N. D. C. & Curran, H. V., 1 Nov 2017, In : Psychological Medicine. 47, 15, p. 2708-2719 12 p.

Research output: Contribution to journalArticle

Open Access
Cannabis
Tobacco
Joints
Placebos
Short-Term Memory
Open Access
Cannabis
Tobacco
Anatomy
Joints
Placebos
3 Citations (Scopus)

Individual and combined effects of cannabis and tobacco on drug reward processing in non-dependent users

Hindocha, C., Lawn, W., Freeman, T. P. & Curran, H. V., 1 Nov 2017, In : Psychopharmacology. 234, 21, p. 3153-3163 11 p.

Research output: Contribution to journalArticle

Open Access
Cannabis
Reward
Tobacco
Pharmaceutical Preparations
Tobacco Products

Psychiatric Co-morbidity in Ketamine and Methamphetamine Dependence: a Retrospective Chart Review

Tang, W. K., Liang, H., Lin, Y., Zhang, C., Tang, A., Chan, F., Freeman, T. P. & Ungvari, G. S., 1 Aug 2017, In : International Journal of Mental Health and Addiction. 15, 4, p. 956-966 11 p.

Research output: Contribution to journalArticle

Open Access
File
Methamphetamine
Ketamine
Psychiatry
Morbidity
Substance-Related Disorders
3 Citations (Scopus)

Ultra-Brief Mindfulness Training Reduces Alcohol Consumption in At-Risk Drinkers: A Randomized Double-Blind Active-Controlled Experiment

Kamboj, S. K., Irez, D., Serfaty, S., Thomas, E., Das, R. K. & Freeman, T. P., 1 Nov 2017, In : International Journal of Neuropsychopharmacology. 20, 11, p. 936-947 12 p.

Research output: Contribution to journalArticle

Open Access
Mindfulness
Alcohol Drinking
Alcohols
Up-Regulation
12 Citations (Scopus)

User characteristics and effect profile of Butane Hash Oil: An extremely high-potency cannabis concentrate

Chan, G. C. K., Hall, W., Freeman, T. P., Ferris, J., Kelly, A. B. & Winstock, A., 1 Sep 2017, In : Drug and Alcohol Dependence. 178, p. 32-38 7 p.

Research output: Contribution to journalArticle

Open Access
File
Cannabis
Oils
Anxiety
butane
Depression
2016
27 Citations (Scopus)

Acute and chronic effects of cannabinoids on effort-related decision-making and reward learning: an evaluation of the cannabis 'amotivational' hypotheses

Lawn, W., Freeman, T. P., Pope, R. A., Joye, A., Harvey, L., Hindocha, C., Mokrysz, C., Moss, A., Wall, M. B., Bloomfield, M. A., Das, R. K., Morgan, C. J., Nutt, D. J. & Curran, H. V., 1 Oct 2016, In : Psychopharmacology. 233, 19-20, p. 3537-3552 16 p.

Research output: Contribution to journalArticle

Open Access
Cannabidiol
Cannabinoids
Cannabis
Reward
Decision Making
19 Citations (Scopus)

AKT1 genotype moderates the acute psychotomimetic effects of naturalistically smoked cannabis in young cannabis smokers

Morgan, C. J. A., Freeman, T. P., Powell, J. & Curran, H. V., 16 Feb 2016, In : Translational Psychiatry. 6, e738.

Research output: Contribution to journalArticle

Open Access
Cannabis
Genotype
Short-Term Memory
Psychotic Disorders
Catechol O-Methyltransferase
2 Citations (Scopus)

A Moderate Dose of Alcohol Does Not Influence Experience of Social Ostracism in Hazardous Drinkers

Buckingham, J., Moss, A., Gyure, K., Ralph, N., Hindocha, C., Lawn, W., Curran, H. V. & Freeman, T. P., Apr 2016, In : Frontiers in Psychology. 7, p. 1-7 7 p., 555.

Research output: Contribution to journalArticle

Open Access
Alcohols
Alcoholism
Bayes Theorem
Cross-Over Studies
Placebos
18 Citations (Scopus)

Are adolescents more vulnerable to the harmful effects of cannabis than adults? A placebo-controlled study in human males

Mokrysz, C., Freeman, T. P., Korkki, S. & Curran, H. V., 29 Nov 2016, In : Translational Psychiatry. 6, 11, p. 1-10 10 p., e961.

Research output: Contribution to journalArticle

Open Access
Cannabis
Placebos
Short-Term Memory
Pharmaceutical Preparations
Episodic Memory
13 Citations (Scopus)

Nitrous oxide speeds the reduction of distressing intrusive memories in an experimental model of psychological trauma

Das, R. K., Tamman, A., Nikolova, V., Freeman, T. P., Bisby, J. A., Lazzarino, A. I. & Kamboj, S. K., 1 Jun 2016, In : Psychological Medicine. 46, 8, p. 1749-1759 11 p.

Research output: Contribution to journalArticle

Nitrous Oxide
Theoretical Models
Post-Traumatic Stress Disorders
Motion Pictures
Surgical Instruments
27 Citations (Scopus)

No Smoke without Tobacco: A Global Overview of Cannabis and Tobacco Routes of Administration and Their Association with Intention to Quit

Hindocha, C., Freeman, T. P., Ferris, J. A., Lynskey, M. T. & Winstock, A. R., Jul 2016, In : Frontiers in Psychiatry . 7, 104.

Research output: Contribution to journalArticle

Open Access
Cannabis
Smoke
Tobacco
Tobacco Use
Motivation
4 Citations (Scopus)

Salience attribution and its relationship to cannabis-induced psychotic symptoms

Bloomfield, M. A. P., Mouchlianitis, E., Morgan, C. J. A., Freeman, T. P., Curran, H. V., Roiser, J. P. & Howes, O. D., 1 Dec 2016, In : Psychological Medicine. 46, 16, p. 3383-3395 13 p.

Research output: Contribution to journalArticle

Open Access
Cannabis
Psychotic Disorders
Dopamine
Marijuana Abuse
Corpus Striatum
2015
14 Citations (Scopus)

A comparison of emotion regulation strategies in response to craving cognitions: Effects on smoking behaviour, craving and affect in dependent smokers

Beadman, M., Das, R. K., Freeman, T. P., Scragg, P., West, R. & Kamboj, S. K., Jun 2015, In : Behaviour Research and Therapy. 69, p. 29-39 11 p.

Research output: Contribution to journalArticle

Cognition
Emotions
Smoking
Cues
Avoidance Learning
48 Citations (Scopus)

Acute effects of delta-9-tetrahydrocannabinol, cannabidiol and their combination on facial emotion recognition: a randomised, double-blind, placebo-controlled study in cannabis users

Hindocha, C., Freeman, T. P., Schafer, G., Gardener, C., Das, R. K., Morgan, C. J. A. & Curran, H. V., 1 Mar 2015, In : European Neuropsychopharmacology. 25, 3, p. 325-334 10 p.

Research output: Contribution to journalArticle

Open Access
Cannabidiol
Dronabinol
Cannabis
Emotions
Placebos
18 Citations (Scopus)

Assessing the translational feasibility of pharmacological drug memory reconsolidation blockade with memantine in quitting smokers

Das, R. K., Hindocha, C., Freeman, T. P., Lazzarino, A. I., Curran, H. V. & Kamboj, S. K., Sep 2015, In : Psychopharmacology. 232, 18, p. 3363-3374 12 p.

Research output: Contribution to journalArticle

Open Access
Memantine
Smoking
Pharmacology
Pharmaceutical Preparations
Cues
32 Citations (Scopus)

Associations between cigarette smoking and cannabis dependence: a longitudinal study of young cannabis users in the United Kingdom

Hindocha, C., Shaban, N. D. C., Freeman, T. P., Das, R. K., Gale, G., Schafer, G., Falconer, C. J., Morgan, C. J. A. & Curran, H. V., 1 Mar 2015, In : Drug and Alcohol Dependence. 148, p. 165-171 7 p.

Research output: Contribution to journalArticle

Open Access
Marijuana Abuse
Cannabis
Tobacco Products
Longitudinal Studies
Smoking
6 Citations (Scopus)

Attentional bias and treatment adherence in substitute-prescribed opiate users

Charles, M., Wellington, C. E., Mokrysz, C., Freeman, T. P., O'Ryan, D. & Curran, H. V., 1 Jul 2015, In : Addictive Behaviors. 46, p. 100-105 6 p.

Research output: Contribution to journalArticle

Opiate Alkaloids
Therapeutics
Patient treatment
Attentional Bias
Recovery
6 Citations (Scopus)

Dopamine, urges to smoke, and the relative salience of drug versus non-drug reward

Freeman, T. P., Das, R. K., Kamboj, S. K. & Curran, H. V., 1 Jan 2015, In : Social Cognitive and Affective Neuroscience. 10, 1, p. 85-92 8 p.

Research output: Contribution to journalArticle

Open Access
Reward
Smoke
Dopamine
Smoking
Pharmaceutical Preparations
65 Citations (Scopus)

Examining the profile of high-potency cannabis and its association with severity of cannabis dependence

Freeman, T. P. & Winstock, A. R., Nov 2015, In : Psychological Medicine. 45, 15, p. 3181-3189 9 p.

Research output: Contribution to journalArticle

Open Access
Marijuana Abuse
Cannabis
Mephitidae
Confidence Intervals
Paranoid Disorders

New challenges raised by ‘legal highs’

Freeman, T. & Richardson, T., Apr 2015, In : The Psychologist. 28, 4, p. 254 - 261 2 p.

Research output: Contribution to journalArticle

Open Access
11 Citations (Scopus)

Recreational 3,4-methylenedioxy-N-methylamphetamine (MDMA) or 'ecstasy' and self-focused compassion: Preliminary steps in the development of a therapeutic psychopharmacology of contemplative practices

Kamboj, S. K., Kilford, E. J., Minchin, S., Moss, A., Lawn, W., Das, R. K., Falconer, C. J., Gilbert, P., Curran, H. V. & Freeman, T. P., 1 Sep 2015, In : Journal of Psychopharmacology . 29, 9, p. 961-970 10 p.

Research output: Contribution to journalArticle

Psychopharmacology
Methamphetamine
Imagery (Psychotherapy)
Psychotherapy
Therapeutics
9 Citations (Scopus)

The effects of nicotine dependence and acute abstinence on the processing of drug and non-drug rewards

Lawn, W., Freeman, T. P., Hindocha, C., Mokrysz, C., Das, R. K., Morgan, C. J. A. & Curran, H. V., 1 Jul 2015, In : Psychopharmacology. 232, 14, p. 2503-2517 15 p.

Research output: Contribution to journalArticle

Tobacco Use Disorder
Reward
Pharmaceutical Preparations
Tobacco Products
Nicotine
2014
15 Citations (Scopus)

Emotional processing deficits in chronic cannabis use: a replication and extension

Hindocha, C., Wollenberg, O., Carter Leno, V., Alvarez, B. O., Curran, H. V. & Freeman, T. P., 1 May 2014, In : Journal of Psychopharmacology . 28, 5, p. 466-471 6 p.

Research output: Contribution to journalArticle

Cannabis
Emotions
Personality
45 Citations (Scopus)

Just say 'know': how do cannabinoid concentrations influence users' estimates of cannabis potency and the amount they roll in joints?

Freeman, T. P., Morgan, C. J. A., Hindocha, C., Schafer, G., Das, R. K. & Curran, H. V., 1 Oct 2014, In : Addiction. 109, 10, p. 1686-1694 9 p.

Research output: Contribution to journalArticle

Cannabinoids
Cannabis
Dronabinol
Cannabidiol
Joints
22 Citations (Scopus)

Long-Term Heavy Ketamine Use is Associated with Spatial Memory Impairment and Altered Hippocampal Activation

Morgan, C. J. A., Dodds, C. M., Furby, H., Pepper, F., Fam, J., Freeman, T. P., Hughes, E., Doeller, C., King, J., Howes, O. & Stone, J. M., 2014, In : Frontiers in Psychiatry . 5, 149.

Research output: Contribution to journalArticle

Open Access
Ketamine
Parahippocampal Gyrus
Memory Disorders
Temporal Lobe
Hippocampus
4 Citations (Scopus)

Tobacco smoking in schizophrenia: investigating the role of incentive salience

Freeman, T. P., Stone, J. M., Orgaz, B., Noronha, L. A., Minchin, S. L. & Curran, H. V., 1 Jul 2014, In : Psychological Medicine. 44, 10, p. 2189-2197 9 p.

Research output: Contribution to journalArticle

Motivation
Schizophrenia
Smoking
Delusions
Tobacco Use Disorder
2013
7 Citations (Scopus)

Associative blocking to reward-predicting cues is attenuated in ketamine users but can be modulated by images associated with drug use

Freeman, T. P., Morgan, C. J. A., Pepper, F., Howes, O. D., Stone, J. M. & Curran, H. V., Jan 2013, In : Psychopharmacology. 225, 1, p. 41-50 10 p.

Research output: Contribution to journalArticle

Ketamine
Reward
Cues
Pharmaceutical Preparations
Schizophrenia
5 Citations (Scopus)

Dopaminergic involvement in effort-based but not impulsive reward processing in smokers

Freeman, T. P., Morgan, C. J. A., Brandner, B., Almahdi, B. & Curran, H. V., 1 Jun 2013, In : Drug and Alcohol Dependence. 130, 1-3, p. 109-114 6 p.

Research output: Contribution to journalArticle

Reward
Processing
Nicotine
Sorting
Drug therapy
16 Citations (Scopus)
Adrenergic Antagonists
N-Methylaspartate
Reward
Meta-Analysis
N-Methyl-D-Aspartate Receptors
2012
74 Citations (Scopus)

Cognitive and subjective effects of mephedrone and factors influencing use of a 'new legal high'

Freeman, T. P., Morgan, C. J. A., Vaughn-Jones, J., Hussain, N., Karimi, K. & Curran, H. V., Apr 2012, In : Addiction. 107, 4, p. 792-800 9 p.

Research output: Contribution to journalArticle

Short-Term Memory
Pharmaceutical Preparations
Internet
Depression
mephedrone
20 Citations (Scopus)

Drug cue induced overshadowing: selective disruption of natural reward processing by cigarette cues amongst abstinent but not satiated smokers

Freeman, T. P., Morgan, C. J. A., Beesley, T. & Curran, H. V., Jan 2012, In : Psychological Medicine. 42, 1, p. 161-171 11 p.

Research output: Contribution to journalArticle

Reward
Tobacco Products
Cues
Pharmaceutical Preparations
Learning
22 Citations (Scopus)

Investigating the interaction between schizotypy, divergent thinking and cannabis use

Schafer, G., Feilding, A., Morgan, C. J. A., Agathangelou, M., Freeman, T. P. & Valerie Curran, H., Mar 2012, In : Consciousness and Cognition. 21, 1, p. 292-298 7 p.

Research output: Contribution to journalArticle

Open Access
Cannabis
Creativity
Psychotic Disorders
Thinking
66 Citations (Scopus)

Sub-chronic impact of cannabinoids in street cannabis on cognition, psychotic-like symptoms and psychological well-being

Morgan, C. J. A., Gardener, C., Schafer, G., Swan, S., Demarchi, C., Freeman, T. P., Warrington, P., Rupasinghe, I., Ramoutar, A., Tan, N., Wingham, G., Lewis, S. & Curran, H. V., Feb 2012, In : Psychological Medicine. 42, 2, p. 391-400 10 p.

Research output: Contribution to journalArticle

Cannabidiol
Cannabinoids
Cannabis
Cognition
Dronabinol
2010
93 Citations (Scopus)

Cannabidiol attenuates the appetitive effects of Delta 9-tetrahydrocannabinol in humans smoking their chosen cannabis

Morgan, C. J. A., Freeman, T. P., Schafer, G. L. & Curran, H. V., 28 Apr 2010, In : Neuropsychopharmacology. 35, 9, p. 1879-1885 7 p.

Research output: Contribution to journalArticle

Cannabidiol
Dronabinol
Cannabis
Smoking
Marijuana Abuse