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2020

A Three-Component Derivatization Protocol for Determining the Enantiopurity of Sulfinamides by 1H and 19F NMR Spectroscopy

Groleau, R. R., Chapman, R. S. L., Ley-Smith, H., Liu, L., James, T. D. & Bull, S. D., 17 Jan 2020, In : Journal of Organic Chemistry. 85, 2, p. 1208-1215

Research output: Contribution to journalArticle

Open Access

Coumarin-based fluorescent probe for the rapid detection of peroxynitrite 'AND' biological thiols

Wu, L., Tian, X., Groleau, R. R., Wang, J., Han, H. H., Reeksting, S. B., Sedgwick, A. C., He, X. P., Bull, S. D. & James, T. D., 2020, In : RSC Advances. 10, 23, p. 13496-13499 4 p.

Research output: Contribution to journalArticle

Open Access

Protein encapsulation: A new approach for improving the capability of small-molecule fluorogenic probes

Han, H. H., Sedgwick, A. C., Shang, Y., Li, N., Liu, T., Li, B. H., Yu, K., Zang, Y., Brewster, J. T., Odyniec, M. L., Weber, M., Bull, S. D., Li, J., Sessler, J. L., James, T. D., He, X. P. & Tian, H., 28 Jan 2020, In : Chemical Science. 11, 4, p. 1107-1113 7 p.

Research output: Contribution to journalArticle

Open Access
4 Citations (Scopus)

Protein Encapsulation: A Nanocarrier Approach to the Fluorescence Imaging of an Enzyme-Based Biomarker

Jia, Z., Han, H. H., Sedgwick, A. C., Williams, G. T., Gwynne, L., Brewster, J. T., Bull, S. D., Jenkins, A. T. A., He, X. P., Schönherr, H., Sessler, J. L. & James, T. D., 3 Jun 2020, In : Frontiers in Chemistry. 8, 389.

Research output: Contribution to journalArticle

Open Access
Open Access
1 Citation (Scopus)

Voltammetric Monitoring of a Solid-Liquid Phase Transition in N,N,N’,N’-Tetraoctyl-2,6-diamino-9,10-anthraquinone (TODAQ)

Ahn, S. Y., Forder, T., Jones, M., Blackburn, R., Fordred, P., Bull, S. & Marken, F., 31 Jan 2020, In : Journal of Solid State Electrochemistry. 24, p. 11-16 6 p.

Research output: Contribution to journalArticle

2019

A boronic acid-based fluorescent hydrogel for monosaccharide detection

Xu, S., Sedgwick, A. C., Elfeky, S. A., Chen, W., Jones, A. S., Williams, G. T., Jenkins, A. T. A., Bull, S. D., Fossey, J. S. & James, T. D., 21 May 2019, In : Frontiers of Chemical Science and Engineering.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

A Selective Deprotection Strategy for the Construction of trans-2-Aminocyclopropanecarboxylic Acid Derived Peptides

Boddaert, T., Taylor, J. E., Bull, S. D. & Aitken, D. J., 4 Jan 2019, In : Organic Letters. 21, 1, p. 100-103 4 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

A Simple Near-Infrared Fluorescent Probe for the Detection of Peroxynitrite

Wu, L., Tian, X., Han, H. H., Wang, J., Groleau, R. R., Tosuwan, P., Wannalerse, B., Sedgwick, A. C., Bull, S. D., He, X. P. & James, T. D., 9 Dec 2019, In : ChemistryOpen. 8, 12, p. 1407-1409 3 p.

Research output: Contribution to journalArticle

Open Access

Azulene-Derived Fluorescent Probe for Bioimaging: Detection of Reactive Oxygen and Nitrogen Species by Two-Photon Microscopy

Murfin, L. C., Weber, M., Park, S. J., Kim, W. T., Lopez-Alled, C. M., McMullin, C. L., Pradaux-Caggiano, F., Lyall, C. L., Kociok-Köhn, G., Wenk, J., Bull, S. D., Yoon, J., Kim, H. M., James, T. D. & Lewis, S. E., 11 Dec 2019, In : Journal of the American Chemical Society. 141, 49, p. 19389-19396 8 p.

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Continuous-flow liquid-phase dehydrogenation of 1,4-cyclohexanedione in a structured multichannel reactor

Ashraf, M. A., Tan, J., Davidson, M. G., Bull, S., Hutchby, M., Mattia, D. & Plucinski, P., 1 Jan 2019, In : Reaction Chemistry & Engineering. 4, 1, p. 27-40 14 p.

Research output: Contribution to journalArticle

Open Access
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2 Citations (Scopus)
12 Downloads (Pure)

Coumarin-based fluorescent 'AND' logic gate probes for the detection of homocysteine and a chosen biological analyte

Wu, L., Gardiner, J. E., Kumawat, L. K., Han, H. H., Guo, R., Li, X., He, X. P., Elmes, R. B. P., Sedgwick, A. C., Bull, S. D. & James, T. D., 27 Aug 2019, In : RSC Advances. 9, 45, p. 26425-26428 4 p.

Research output: Contribution to journalArticle

Open Access
4 Citations (Scopus)

Dual enzyme activated fluorescein based fluorescent probe

Odyniec, M. L., Gardiner, J. E., Sedgwick, A. C., He, X. P., Bull, S. D. & James, T. D., 1 Mar 2019, In : Frontiers of Chemical Science and Engineering.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

ESIPT-based fluorescence probe for the ratiometric detection of superoxide

Wu, L., Liu, L., Han, H. H., Tian, X., Odyniec, M. L., Feng, L., Sedgwick, A. C., He, X. P., Bull, S. D. & James, T. D., 21 Feb 2019, In : New Journal of Chemistry. 43, 7, p. 2875-2877 3 p.

Research output: Contribution to journalArticle

Open Access
4 Citations (Scopus)

Exposing the Interplay Between Enzyme Turnover, Protein Dynamics and the Membrane Environment in Monoamine Oxidase B

Jones, H. B. L., Crean, R. M., Mullen, A., Kendrick, E., Bull, S. D., Wells, S. A., Carbery, D. R., MacMillan, F., van der Kamp, M. W. & Pudney, C. R., 7 May 2019, In : Biochemistry. 58, 18, p. 2362-2372 11 p.

Research output: Contribution to journalArticle

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Long Wavelength TCF-Based Fluorescent Probe for the Detection of Alkaline Phosphatase in Live Cells

Gwynne, L., Sedgwick, A. C., Gardiner, J. E., Williams, G. T., Kim, G., Maillard, J. Y., Jenkins, T., Bull, S. D., Sessler, J. L., Yoon, J. & James, T. D., 30 Apr 2019, In : Frontiers in Chemistry. 7, APR, p. 1-6 6 p., 255.

Research output: Contribution to journalArticle

Open Access
4 Citations (Scopus)

Peroxynitrite Activated Drug Conjugate Systems Based on a Coumarin Scaffold Toward the Application of Theranostics

Odyniec, M. L., Han, H. H., Gardiner, J. E., Sedgwick, A. C., He, X. P., Bull, S. D. & James, T. D., 5 Dec 2019, In : Frontiers in Chemistry. 7, 775.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

Reaction-Based Fluorescent Probes for the Detection and Imaging of Reactive Oxygen, Nitrogen, and Sulfur Species

Wu, L., Sedgwick, A. C., Sun, X., Bull, S. D., He, X. P. & James, T. D., 17 Sep 2019, In : Accounts of Chemical Research. 52, 9, p. 2582-2597 16 p.

Research output: Contribution to journalArticle

Open Access
22 Citations (Scopus)

Reaction-based indicator displacement assay (RIA) for the development of a triggered release system capable of biofilm inhibition

Patenall, B. L., Williams‡, G. T., Gwynne, L., Stephens, L. J., Lampard, E. V., Hathaway, H. J., Thet, N. T., Young, A. E., Sutton, M. J., Short, R. D., Bull, S. D., James, T. D., Sedgwick, A. C. & Jenkins, A. T. A., 12 Dec 2019, In : Chemical Communications. 55, 100, p. 15129-15132 4 p.

Research output: Contribution to journalArticle

Open Access
2018

1,1-Diacyloxy-1-phenylmethanes as versatile N-acylating agents for amines

Chapman, R. S. L., Tibbetts, J. D. & Bull, S. D., 20 Sep 2018, In : Tetrahedron. 74, 38, p. 5330-5339 10 p.

Research output: Contribution to journalArticle

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2 Citations (Scopus)
28 Downloads (Pure)

'AND'-based fluorescence scaffold for the detection of ROS/RNS and a second analyte

Odyniec, M. L., Sedgwick, A. C., Swan, A. H., Weber, M., Tang, T. M. S., Gardiner, J. E., Zhang, M., Jiang, Y. B., Kociok-Kohn, G., Elmes, R. B. P., Bull, S. D., He, X. P. & James, T. D., 27 Jun 2018, In : Chemical Communications. 54, p. 8466-8469 4 p.

Research output: Contribution to journalArticle

Open Access
17 Citations (Scopus)

An ESIPT Probe for the Ratiometric Imaging of Peroxynitrite Facilitated by Binding to Aβ-Aggregates

Sedgwick, A. C., Dou, W. T., Jiao, J. B., Wu, L., Williams, G. T., Jenkins, A. T. A., Bull, S. D., Sessler, J. L., He, X. P. & James, T. D., 31 Oct 2018, In : Journal of the American Chemical Society. 140, 43, p. 14267-14271 5 p.

Research output: Contribution to journalArticle

Open Access
47 Citations (Scopus)

A simple umbelliferone based fluorescent probe for the detection of nitroreductase

Sedgwick, A. C., Hayden, A., Hill, B., Bull, S. D., Elmes, R. B. P. & James, T. D., 1 Jun 2018, In : Frontiers of Chemical Science and Engineering. 12, 2, p. 311-314 4 p.

Research output: Contribution to journalArticle

Open Access
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6 Citations (Scopus)
28 Downloads (Pure)

Boronate-Based Fluorescence Probes for the Detection of Hydrogen Peroxide

Lampard, E. V., Sedgwick, A. C., Sun, X., Filer, K. L., Hewins, S. C., Kim, G., Yoon, J., Bull, S. D. & James, T. D., 1 Mar 2018, In : ChemistryOpen. 7, 3, p. 262-265 4 p.

Research output: Contribution to journalArticle

Open Access
9 Citations (Scopus)

Correction: A bodipy based hydroxylamine sensor (Chemical Communications (2017) 53 (10441-10443) DOI: 10.1039/C7CC05872A)

Sedgwick, A. C., Chapman, R. S. L., Gardiner, J. E., Peacock, L. R., Kim, G., Yoon, J., Bull, S. D. & James, T. D., 4 Oct 2018, In : Chemical Communications. 54, 77, p. 10922 1 p.

Research output: Contribution to journalArticle

Open Access

Correction: Boronate based fluorescence (ESIPT) probe for peroxynitrite(Chem. Commun. (2016) 52 (12350–12352) DOI: 10.1039/C6CC06829D)

Sedgwick, A. C., Sun, X., Kim, G., Yoon, J., Bull, S. D. & James, T. D., 28 Sep 2018, In : Chemical Communications. 54, 76, p. 10775 1 p.

Research output: Contribution to journalArticle

Open Access

Dual-function cellulose composites for fluorescence detection and removal of fluoride

Li, M., Liu, Z., Wang, H. C., Sedgwick, A. C., Gardiner, J. E., Bull, S. D., Xiao, H. N. & James, T. D., 1 Feb 2018, In : Dyes and Pigments. 149, p. 669-675 7 p.

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18 Citations (Scopus)
39 Downloads (Pure)

Dye Displacement Assay for Saccharides using Benzoxaborole Hydrogels

Lampard, E. V., Sedgwick, A. C., Sombuttan, T., Williams, G. T., Wannalerse, B., Jenkins, A. T. A., Bull, S. D. & James, T. D., 1 Mar 2018, In : ChemistryOpen. 7, 3, p. 266-268 3 p.

Research output: Contribution to journalArticle

Open Access
5 Citations (Scopus)

Electrochemically Driven C-H Hydrogen Abstraction Processes with the Tetrachloro-Phthalimido-N-Oxyl (Cl4PINO) Catalyst

Marken, F., Buckingham, M. A., Bull, S., Cunningham, W., Buchard, A., Folli, A. & Murphy, D., 1 Aug 2018, In : Electroanalysis. 30, 8, p. 1706-1713 8 p.

Research output: Contribution to journalArticle

Open Access
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1 Citation (Scopus)
25 Downloads (Pure)

ESIPT-based fluorescence probe for the rapid detection of hypochlorite (HOCl/ClO-)

Wu, L., Yang, Q., Liu, L., Sedgwick, A. C., Cresswell, A. J., Bull, S. D., Huang, C. & James, T. D., 4 Jul 2018, In : Chemical Communications. 54, 61, p. 8522-8525 4 p.

Research output: Contribution to journalArticle

Open Access
39 Citations (Scopus)

ESIPT-based fluorescence probe for the rapid detection of peroxynitrite ‘AND' biological thiols

Wu, L., Han, H. H., Liu, L., Gardiner, J. E., Sedgwick, A. C., Huang, C., Bull, S. D., He, X. P. & James, T. D., 14 Oct 2018, In : Chemical Communications. 54, 80, p. 11336-11339 4 p.

Research output: Contribution to journalArticle

Open Access
24 Citations (Scopus)

ESIPT-based ratiometric fluorescence probe for the intracellular imaging of peroxynitrite

Wu, L., Wang, Y., Weber, M., Liu, L., Sedgwick, A. C., Bull, S. D., Huang, C. & James, T. D., 7 Aug 2018, In : Chemical Communications. 54, 71, p. 9953-9956 4 p.

Research output: Contribution to journalArticle

Open Access
36 Citations (Scopus)
Open Access
File
17 Citations (Scopus)
42 Downloads (Pure)

Formyloxyacetoxyphenylmethane and 1,1-diacylals as versatile O-formylating and O-acylating reagents for alcohols

Chapman, R., Francis, M., Lawrence, R., Tibbetts, J. & Bull, S., 1 Nov 2018, In : Tetrahedron. 74, 44, p. 6442-6452 11 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Long-wavelength TCF-based fluorescence probes for the detection and intracellular imaging of biological thiols

Sedgwick, A. C., Gardiner, J. E., Kim, G., Yevglevskis, M., Lloyd, M. D., Jenkins, A. T. A., Bull, S. D., Yoon, J. & James, T. D., 11 May 2018, In : Chemical Communications. 54, 38, p. 4786-4789 4 p.

Research output: Contribution to journalArticle

Open Access
26 Citations (Scopus)

The development of a novel AND logic based fluorescence probe for the detection of peroxynitrite and GSH

Sedgwick, A. C., Han, H. H., Gardiner, J. E., Bull, S. D., He, X-P. & James, T. D., 21 Apr 2018, In : Chemical Science. 9, 15, p. 3672-3676 5 p.

Research output: Contribution to journalArticle

Open Access
48 Citations (Scopus)

Uncovering the relationship between the change in heat capacity for enzyme catalysis and vibrational frequency through isotope effect studies

Jones, H. B. L., Crean, R. M., Matthews, C., Troya, A. B., Danson, M. J., Bull, S. D., Arcus, V. L., Van Der Kamp, M. W. & Pudney, C. R., 1 Jun 2018, In : ACS Catalysis. 8, 6, p. 5340-5349 10 p.

Research output: Contribution to journalArticle

Open Access
File
6 Citations (Scopus)
54 Downloads (Pure)
2017

A bodipy based hydroxylamine sensor

Sedgwick, A. C., Chapman, R. S. L., Gardiner, J. E., Peacock, L. R., Kim, G., Yoon, J., Bull, S. D. & James, T. D., 25 Sep 2017, In : Chemical Communications. 53, 75, p. 10441-10443

Research output: Contribution to journalArticle

Open Access
19 Citations (Scopus)

Automation of route identification and optimisation based on data-mining and chemical intuition

Lapkin, A. A., Heer, P. K., Jacob, P. M., Hutchby, M., Cunningham, W., Bull, S. D. & Davidson, M. G., 1 Sep 2017, In : Faraday Discussions. 202, p. 483-496 14 p.

Research output: Contribution to journalArticle

Open Access
12 Citations (Scopus)

Azulene–boronate esters: colorimetric indicators for fluoride in drinking water

Lopez-Alled, C. M., Sanchez Fernandez, A., Edler, K., Sedgwick, A., Bull, S., McMullin, C., Kociok-Kohn, G., James, T., Wenk, J. & Lewis, S., 4 Dec 2017, In : Chemical Communications. 53, 93, p. 12580-12583 4 p.

Research output: Contribution to journalArticle

Open Access
33 Citations (Scopus)

Long-wavelength fluorescent boronate probes for the detection and intracellular imaging of peroxynitrite

Sedgwick, A. C., Han, H. H., Gardiner, J. E., Bull, S. D., He, X-P. & James, T. D., 11 Dec 2017, In : Chemical Communications. 53, 95, p. 12822-12825

Research output: Contribution to journalArticle

Open Access
54 Citations (Scopus)

Rapid determination of enantiomeric excess via NMR spectroscopy: A research-informed experiment

Fossey, J. S., Anslyn, E. V., Brittain, W. D. G., Bull, S. D., Chapin, B. M., Le Duff, C. S., James, T. D., Lees, G., Lim, S., Lloyd, J. A. C., Manville, C. V., Payne, D. T. & Roper, K. A., 10 Jan 2017, In : Journal of Chemical Education. 94, 1, p. 79-84 6 p.

Research output: Contribution to journalArticle

Open Access
12 Citations (Scopus)

Reaction-based indicator displacement assay (RIA) for the colorimetric and fluorometric detection of hydrogen peroxide

Sun, X., Odyniec, M. L., Sedgwick, A. C., Lacina, K., Xu, S., Qiang, T., Bull, S. D., Marken, F. & James, T. D., 1 Jun 2017, In : Organic Chemistry Frontiers. 4, 6, p. 1058-1062 5 p.

Research output: Contribution to journalArticle

Open Access
13 Citations (Scopus)
2016

A Protocol for NMR Analysis of the Enantiomeric Excess of Chiral Diols Using an Achiral Diboronic Acid Template

Tickell, D. A., Lampard, E. V., Lowe, J. P., James, T. D. & Bull, S. D., 6 Jul 2016, In : Journal of Organic Chemistry. 81, 15, p. 6795–6799

Research output: Contribution to journalArticle

Open Access
File
7 Citations (Scopus)
119 Downloads (Pure)

Aza-conjugate addition methodology for the synthesis of N-hydroxy-isoindolin-1-ones

Royo, S., Chapman, R. S. L., Sim, A. M., Peacock, L. R. & Bull, S. D., 4 Mar 2016, In : Organic Letters. 18, 5, p. 1146-1149 4 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Boronate based fluorescence (ESIPT) probe for peroxynitrite

Sedgwick, A., Sun, X., Kim, G., Yoon, J., Bull, S. D. & James, T. D., 25 Oct 2016, In : Chemical Communications. 52, 83, p. 12350-12352 3 p.

Research output: Contribution to journalArticle

Open Access
68 Citations (Scopus)

DBN hexafluorophosphate salts as convenient sulfonylating and phosphonylating agents

Jones, C. S., Bull, S. D. & Williams, J. M. J., 28 Sep 2016, In : Organic and Biomolecular Chemistry. 14, 36, p. 8452-8456 5 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Hydrodynamic rocking disc electrode study of the TEMPO-mediated catalytic oxidation of primary alcohols

Ahn, S. Y., Fisher, A. C., Buchard, A., Bull, S. D., Bond, A. M. & Marken, F., Sep 2016, In : Electroanalysis. 28, 9, p. 2093-2103

Research output: Contribution to journalArticle

Open Access
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4 Citations (Scopus)
106 Downloads (Pure)

Orthogonally protected Schöllkopf’s bis-lactim ethers for the asymmetric synthesis of α-amino acid derivatives and dipeptide esters

Hutchby, M., Sedgwick, A. C. & Bull, S. D., Jul 2016, In : Synthesis. 48, 13, p. 2036-2049

Research output: Contribution to journalArticle

7 Citations (Scopus)