Projects per year
Personal profile
Research interests
Synthetic chemistry is the cornerstone of the natural sciences where it serves as a fundamental technology for the preparation of structurally complex materials on a molecular scale. Complexity in molecules is often associated with chirality - the fundamental property of a structure that renders it non-superimposable on its mirror image. The synthesis of chiral molecules is a challenging undertaking and we are interested in developing novel, atom efficient strategies for the asymmetric synthesis of highly desirable chiral fragments. Towards this aim, my research interests can be categorised into four main areas - asymmetric synthesis, biotransformations, combinatorial chemistry and bioorganic chemistry.
Research workers within my group will be exposed to a wide range of 'state of the art' synthetic and analytical techniques which are ideally suited to a career in both academia and industry. For more information visit the Bull Group homepage.
Research Interests
- Asymmetic Synthesis
- Biotransformations
- Combinatorial Chemistry
- Bioorganic Synthesis
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Projects
Global Collaboration Scheme - A biorefinery approach for the conversion of grape waste into value-added chemicals.
Bull, S., Jones, M. & Patterson, D.
1/04/14 → 22/08/14
Project: Research-related funding
Global Mobility Scheme - chemical sensors for use by pharma industry
James, T., Bull, S. & Frost, C.
1/05/13 → 1/12/14
Project: Research-related funding
Terpene-based Manufacturing for Sustainable Chemical feedstocks
Davidson, M., Bull, S., Frost, C., Jones, M. & Scott, J. L.
Engineering and Physical Sciences Research Council
1/02/13 → 31/07/18
Project: Research council
KTP with Quotient Diaganostics Ltd
5/11/12 → 4/11/15
Project: Central government, health and local authorities
Research Output
A Three-Component Derivatization Protocol for Determining the Enantiopurity of Sulfinamides by 1H and 19F NMR Spectroscopy
Groleau, R. R., Chapman, R. S. L., Ley-Smith, H., Liu, L., James, T. D. & Bull, S. D., 17 Jan 2020, In : Journal of Organic Chemistry. 85, 2, p. 1208-1215Research output: Contribution to journal › Article
Open Access
Protein encapsulation: A new approach for improving the capability of small-molecule fluorogenic probes
Han, H. H., Sedgwick, A. C., Shang, Y., Li, N., Liu, T., Li, B. H., Yu, K., Zang, Y., Brewster, J. T., Odyniec, M. L., Weber, M., Bull, S. D., Li, J., Sessler, J. L., James, T. D., He, X. P. & Tian, H., 28 Jan 2020, In : Chemical Science. 11, 4, p. 1107-1113 7 p.Research output: Contribution to journal › Article
Open Access
Sensing Peroxynitrite in Different Organelles of Murine RAW264.7 Macrophages With Coumarin-Based Fluorescent Probes
Weber, M., Yamada, N., Tian, X., Bull, S. D., Minoshima, M., Kikuchi, K., Mackenzie, A. B. & James, T. D., 20 Feb 2020, In : Frontiers in Chemistry. 8, 39.Research output: Contribution to journal › Article
Open Access
Sustainable Catalytic Protocols for the Solvent Free Epoxidation and (anti)-Dihydroxylation of the Alkene Bonds of Biorenewable Terpene Feedstocks Using H2O2 as Oxidant
Bull, S., Cunningham, W., Tibbetts, J., Hutchby, M., Smug, K. A., Davidson, M., Hintermair, U. & Plucinski, P., 21 Jan 2020, In : Green Chemistry. 22, 2, p. 513-524Research output: Contribution to journal › Article
Open Access
A boronic acid-based fluorescent hydrogel for monosaccharide detection
Xu, S., Sedgwick, A. C., Elfeky, S. A., Chen, W., Jones, A. S., Williams, G. T., Jenkins, A. T. A., Bull, S. D., Fossey, J. S. & James, T. D., 21 May 2019, In : Frontiers of Chemical Science and Engineering.Research output: Contribution to journal › Article
Open Access
1
Citation
(Scopus)
Datasets
A Simple Protocol for NMR Analysis of the Enantiomeric Excess of Chiral Diols Using an Achiral Diboronic Acid Template
Tickell, D. (Creator), Lampard, E. (Creator), Lowe, J. (Creator), James, T. (Creator), Bull, S. (Creator), University of Bath, 2016
DOI: 10.15125/BATH-00211
Dataset
Data from "A bodipy based hydroxylamine sensor"
James, T. (Creator), Sedgwick, A. (Creator), University of Bath, 2017
DOI: 10.15125/BATH-00381
Dataset
Selective Electrochemiluminescent Sensing of Saccharides using Boronic Acid-Modified Coreactant
James, T. (Creator), University of Bath, 2016
DOI: 10.15125/BATH-00254
Dataset
Boronate based fluorescence (ESIPT) probe for peroxynitrite
Sedgwick, A. (Creator), Sun, X. (Creator), Kim, G. (Creator), Yoon, J. (Creator), Bull, S. (Creator), James, T. (Creator), University of Bath, 2016
DOI: 10.15125/BATH-00252
Dataset
Thesis
Alcohol Dehydrogenases from the thermophile Geobacillus thermoglucosidasius
Author: Williams, L., 23 Nov 2016Supervisor: Bull, S. (Supervisor) & Danson, M. (Supervisor)
Student thesis: Doctoral Thesis › PhD
File
A Novel Methodology for the Asymmetric Synthesis of beta-Lactams and beta-Amino Acids
Author: Evans, C., 30 Jun 2012Supervisor: Bull, S. (Supervisor)
Student thesis: Doctoral Thesis › PhD
File
Benzoxaboroles and Boronic Acids for Sensing Applications
Author: Lampard, E., 12 Jan 2018Supervisor: James, T. (Supervisor) & Bull, S. (Supervisor)
Student thesis: Doctoral Thesis › PhD
File
Carbohydrate Directed Photoaffinity Labelling
Author: Fowle, C., 24 Jan 2018Supervisor: James, T. (Supervisor) & Bull, S. (Supervisor)
Student thesis: Doctoral Thesis › PhD
File
Catalytic Conversion of Terpene Feedstocks into value-added Chemicals and Commodity Chemicals
Author: Cunningham, W., 20 Sep 2018Supervisor: Bull, S. (Supervisor) & Plucinski, P. (Supervisor)
Student thesis: Doctoral Thesis › PhD
File