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Personal profile

Research interests

Synthetic chemistry is the cornerstone of the natural sciences where it serves as a fundamental technology for the preparation of structurally complex materials on a molecular scale. Complexity in molecules is often associated with chirality - the fundamental property of a structure that renders it non-superimposable on its mirror image. The synthesis of chiral molecules is a challenging undertaking and we are interested in developing novel, atom efficient strategies for the asymmetric synthesis of highly desirable chiral fragments. Towards this aim, my research interests can be categorised into four main areas - asymmetric synthesis, biotransformations, combinatorial chemistry and bioorganic chemistry.

Research workers within my group will be exposed to a wide range of 'state of the art' synthetic and analytical techniques which are ideally suited to a career in both academia and industry. For more information visit the Bull Group homepage.

Research Interests

  • Asymmetic Synthesis
  • Biotransformations
  • Combinatorial Chemistry
  • Bioorganic Synthesis

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RS International COST share with Japan

Bull, S.

The Royal Society


Project: Research council

KTP with Quotient Diaganostics Ltd

James, T. & Bull, S.

Innovate UK


Project: Central government, health and local authorities

Research Output

A Three-Component Derivatization Protocol for Determining the Enantiopurity of Sulfinamides by 1H and 19F NMR Spectroscopy

Groleau, R. R., Chapman, R. S. L., Ley-Smith, H., Liu, L., James, T. D. & Bull, S. D., 17 Jan 2020, In : Journal of Organic Chemistry. 85, 2, p. 1208-1215

Research output: Contribution to journalArticle

Open Access

Protein encapsulation: A new approach for improving the capability of small-molecule fluorogenic probes

Han, H. H., Sedgwick, A. C., Shang, Y., Li, N., Liu, T., Li, B. H., Yu, K., Zang, Y., Brewster, J. T., Odyniec, M. L., Weber, M., Bull, S. D., Li, J., Sessler, J. L., James, T. D., He, X. P. & Tian, H., 28 Jan 2020, In : Chemical Science. 11, 4, p. 1107-1113 7 p.

Research output: Contribution to journalArticle

Open Access
Open Access

A boronic acid-based fluorescent hydrogel for monosaccharide detection

Xu, S., Sedgwick, A. C., Elfeky, S. A., Chen, W., Jones, A. S., Williams, G. T., Jenkins, A. T. A., Bull, S. D., Fossey, J. S. & James, T. D., 21 May 2019, In : Frontiers of Chemical Science and Engineering.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)


A Simple Protocol for NMR Analysis of the Enantiomeric Excess of Chiral Diols Using an Achiral Diboronic Acid Template

Tickell, D. (Creator), Lampard, E. (Creator), Lowe, J. (Creator), James, T. (Creator), Bull, S. (Creator), University of Bath, 2016


Data from "A bodipy based hydroxylamine sensor"

James, T. (Creator), Sedgwick, A. (Creator), University of Bath, 2017


Boronate based fluorescence (ESIPT) probe for peroxynitrite

Sedgwick, A. (Creator), Sun, X. (Creator), Kim, G. (Creator), Yoon, J. (Creator), Bull, S. (Creator), James, T. (Creator), University of Bath, 2016



Alcohol Dehydrogenases from the thermophile Geobacillus thermoglucosidasius

Author: Williams, L., 23 Nov 2016

Supervisor: Bull, S. (Supervisor) & Danson, M. (Supervisor)

Student thesis: Doctoral ThesisPhD


A Novel Methodology for the Asymmetric Synthesis of beta-Lactams and beta-Amino Acids

Author: Evans, C., 30 Jun 2012

Supervisor: Bull, S. (Supervisor)

Student thesis: Doctoral ThesisPhD


Benzoxaboroles and Boronic Acids for Sensing Applications

Author: Lampard, E., 12 Jan 2018

Supervisor: James, T. (Supervisor) & Bull, S. (Supervisor)

Student thesis: Doctoral ThesisPhD


Carbohydrate Directed Photoaffinity Labelling

Author: Fowle, C., 24 Jan 2018

Supervisor: James, T. (Supervisor) & Bull, S. (Supervisor)

Student thesis: Doctoral ThesisPhD


Catalytic Conversion of Terpene Feedstocks into value-added Chemicals and Commodity Chemicals

Author: Cunningham, W., 20 Sep 2018

Supervisor: Bull, S. (Supervisor) & Plucinski, P. (Supervisor)

Student thesis: Doctoral ThesisPhD