• 3 SOUTH 1.02

20022018
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Personal profile

Research interests

I'm Director of Studies for the MSc in Chemistry for Drug Discovery and MRes in Chemistry programmes and teach Organic Chemistry and Drug Discovery. My Postdoctoral research focussed on the synthesis of fluorescent and electrochemical sensors for biomedical applications with industrial partners for uses such DNA detection and blood sugar level monitoring and this has shaped my interests in the application of synthetic organic chemistry to healthcare challenges.

I'm active in Widening Participation and Outreach activities, the Salters' Festivals of Chemistry and the Goldsmiths Company's "Sustainable Energy Residential Course" for teachers.

Research Interests

My current research interests are in the areas of novel anti-MRSA drugs and targetted anti-cancer drugs that utilise reversible cyclisation to become activated in the tumor cell. My other area of interest is in the development of new tunable fluorophores with orthogonal sites of attachment to biological targets.

Personal page

Keywords

  • QD Chemistry
  • Synthetic Organic Chemistry
  • Fluorescence Spectroscopy
  • Electrochemistry
  • Sensors
  • Sensing
  • Organic Chemistry
  • Boronic Acids
  • Curcumin
  • Fluorescence Sensors
  • Saccharides
  • Sugars

Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 5 Similar Profiles
Boronic Acids Chemical Compounds
Fluorescence Chemical Compounds
Acids Engineering & Materials Science
Assays Chemical Compounds
Derivatives Chemical Compounds
Oligonucleotides Engineering & Materials Science
Labels Chemical Compounds
Imaging techniques Chemical Compounds

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Research Output 2002 2018

Analysis of Protein Glycation Using Phenylboronate Acrylamide Gel Electrophoresis

Pereira Morais, M., Munir, O. K., Flower, S., Williams, R. J., James, T. & Van Den Elsen, J., 14 Nov 2018, Electrophoretic Separation of Proteins: Methods and Protocols. T. Kurien, B. & Hal Scofield, R. (eds.). New York, U. S. A.: Humana Press, p. 161-175 (Methods in Molecular Biology; vol. 1855).

Research output: Chapter in Book/Report/Conference proceedingChapter

5 Citations

Behavior of Supramolecular Assemblies of Radiometal-Filled and Fluorescent Carbon Nanocapsules In Vitro and In Vivo

Ge, H., Riss, P. J., Mirabello, V., Calatayud, D. G., Flower, S. E., Arrowsmith, R. L., Fryer, T. D., Hong, Y., Sawiak, S., Jacobs, R. M. J., Botchway, S. W., Tyrrell, R. M., James, T. D., Fossey, J. S., Dilworth, J. R., Aigbirhio, F. I. & Pascu, S. I., 14 Sep 2017, In : Chem. 3, 3, p. 437-460

Research output: Contribution to journalArticle

Open Access
File
Nanocapsules
Carbon Nanotubes
beta-Glucans
Carbon
Optical Imaging

Materials and methods for analysing glycation

Flower, S., James, T., Van Den Elsen, J. & Pereira, M., 2016, IPC No. G01 N27/447(200.01), Patent No. US 2016/282355 A1

Research output: Patent

Open Access
material
method
48 Citations

Reaction-based Indicator displacement Assay (RIA) for the selective colorimetric and fluorometric detection of peroxynitrite

Sun, X., Lacina, K., Ramsamy, E. C., Flower, S. E., Fossey, J. S., Qian, X., Anslyn, E. V., Bull, S. D. & James, T. D., 1 May 2015, In : Chemical Science. 6, 5, p. 2963-2967

Research output: Contribution to journalArticle

Open Access
File

An enzyme-less bis-boronic acid modified electrode for glucose sensing in human blood serum

Regan, E. M., Flower, S. E., Wang, H-C., Fossey, J. S., James, T. D. & Estrela, P., 2014, (Unpublished).

Research output: Contribution to conferencePoster

Boronic Acids
Blood
Glucose
Electrodes
Enzymes

Thesis

Lewis Acid Mediated Reactions of Olefins with Carbonyls

Author: Flower, S., 11 Dec 2002

Supervisor: Willis, M. (Supervisor)

Student thesis: Doctoral ThesisPhD