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Research Output 1988 2019

Tumour infiltrating lymphocytes and immune-related genes as predictors of outcome in pancreatic adenocarcinoma

D'Angelo, A., Sobhani, N., Roviello, G., Bagby, S., Bonazza, D., Bottin, C., Giudici, F., Zanconati, F., De Manzini, N., Guglielmi, A. & Generali, D., 5 Aug 2019, In : PLoS ONE. 14, 8, e0219566.

Research output: Contribution to journalArticle

Open Access
2018
2 Citations (Scopus)

Distinctive phosphoinositide- A and Ca2+ binding properties of normal and cognitive performance-linked variant forms of KIBRA C2 domain

Posner, M. G., Upadhyay, A., Ishima, R., Kalli, A. C., Harris, G., Kremerskothen, J., Sansom, M. S. P., Crennell, S. J. & Bagby, S., 15 Jun 2018, In : The Journal of biological chemistry. 293, 24, p. 9335-9344

Research output: Contribution to journalArticle

Open Access
Phosphatidylinositols
Membranes
Nuclear magnetic resonance
Calcium
Titration
Open Access
1 Citation (Scopus)

Resolving the complex Bordetella pertussis genome using barcoded nanopore sequencing

Ring, N., Abrahams, J. S., Jain, M., Olsen, H., Preston, A. & Bagby, S., 28 Nov 2018, In : Microbial Genomics. 4, 11, p. 1-13 13 p.

Research output: Contribution to journalArticle

Open Access
2017

A modular sensor platform based on a versatile supramolecular multi-enzyme complex directly attached to graphene

Alshammari, A., Posner, M., Upadhyay, A., Bashir, M., Marken, F., Bagby, S. & Ilie, A., 2017.

Research output: Contribution to conferencePoster

Protein dynamics revealed by CPMG dispersion

Ishima, R. & Bagby, S., Jul 2017, Modern Magnetic Resonance, 2nd edition. Webb, G. (ed.). 9783319283876: Springer, p. 435-452

Research output: Chapter in Book/Report/Conference proceedingChapter

gills
nuclear magnetic resonance spectroscopy
proteins
methodology
2016
9 Citations (Scopus)
83 Downloads (Pure)

A Modular Bio-Platform Based on a Versatile Supramolecular Multi-Enzyme Complex Directly Attached to Graphene

Alshammari, A., Posner, M. G., Upadhyay, A., Marken, F., Bagby, S. & Ilie, A., 17 Aug 2016, In : ACS Applied Materials and Interfaces. 8, 32, p. 21077–21088 12 p.

Research output: Contribution to journalArticle

Open Access
File
Graphite
Graphene
Enzymes
Proteins
Acyltransferases

Extracellular fibrinogen binding protein (Efb) from S. aureus inhibits the formation of platelet/leukocyte complexes

Pula, G., Posner, M., Upadhyay, A., Vara, D. & Bagby, S., 2016.

Research output: Contribution to conferencePoster

6 Citations (Scopus)
49 Downloads (Pure)

Extracellular Fibrinogen-binding Protein (Efb) from Staphylococcus aureus Inhibits the Formation of Platelet-Leukocyte Complexes

Posner, M. G., Upadhyay, A., Alsheikh Abubaker, A., Fortunato, T. M., Vara, D., Canobbio, I., Bagby, S. & Pula, G., 5 Feb 2016, In : Journal of Biological Chemistry. 291, 6, p. 2764-2776 22 p.

Research output: Contribution to journalArticle

Open Access
Platelets
Fibrinogen
Staphylococcus aureus
Carrier Proteins
Leukocytes

Use of MinION data to assemble the 67% GC genome sequence of Bordetella pertussis

Bagby, S., Jain, M., Olsen, H., Preston, A. & Akeson, M., 2015.

Research output: Contribution to conferencePoster

101 Citations (Scopus)
68 Downloads (Pure)

YAP is essential for tissue tension to ensure vertebrate 3D body shape

Porazinski, S., Wang, H., Asaoka, Y., Behrndt, M., Miyamoto, T., Morita, H., Hata, S., Sasaki, T., Krens, S. F. G., Osada, Y., Asaka, S., Momoi, A., Linton, S., Miesfeld, J. B., Link, B. A., Senga, T., Castillo-Morales, A., Urrutia, A. O., Shimizu, N., Nagase, H. & 6 others, Matsuura, S., Bagby, S., Kondoh, H., Nishina, H., Heisenberg, C. P. & Furutani-Seiki, M., 14 May 2015, In : Nature. 521, 7551, p. 217-221 5 p.

Research output: Contribution to journalArticle

Open Access
File
Vertebrates
Gravitation
Oryzias
Embryonic Structures
Actomyosin
2014
2 Citations (Scopus)
70 Downloads (Pure)

Comparative genomic analysis reveals 2-oxoacid dehydrogenase complex lipoylation correlation with aerobiosis in archaea

Borziak, K., Posner, M., Upadhyay, A., Danson, M., Bagby, S. & Dorus, S., 28 Jan 2014, In : PLoS ONE. 9, p. 1 - 9 9 p., e87063.

Research output: Contribution to journalArticle

Open Access
File
Aerobiosis
Lipoylation
Keto Acids
aerobiosis
Archaea
10 Citations (Scopus)
120 Downloads (Pure)

Transient expression in HEK 293 cells: An alternative to E. coli for the production of secreted and intracellular mammalian proteins

Nettleship, J. E., Watson, P. J., Rahman-Huq, N., Fairall, L., Posner, M. G., Upadhyay, A., Reddivari, Y., Chamberlain, J. M. G., Kolstoe, S. E., Bagby, S., Schwabe, J. W. R. & Owens, R. J., 16 Nov 2014, In : Methods in Molecular Biology. 1258, p. 209-222 14 p.

Research output: Contribution to journalArticle

Open Access
File
HEK293 Cells
Escherichia coli
Recombinant Proteins
Transfection
Proteins

J coupling

Bagby, S., 2013, Encyclopedia of Biophysics. Roberts, G. C. K. (ed.). Springer

Research output: Chapter in Book/Report/Conference proceedingChapter

nuclear spin
chemical bonds
electron spin
scalars
nuclei
8 Citations (Scopus)
71 Downloads (Pure)

Post-translational modification in the archaea: structural characterization of multi-enzyme complex lipoylation

Posner, M. G., Upadhyay, A., Crennell, S., Watson, A. J. A., Dorus, S., Danson, M. J. & Bagby, S., 15 Jan 2013, In : Biochemical Journal. 449, 2, p. 415-425 11 p.

Research output: Contribution to journalArticle

Open Access
File
Lipoylation
Archaea
Post Translational Protein Processing
Enzymes
Protein C
2012
5 Citations (Scopus)
56 Downloads (Pure)

The Hippo pathwaya: Key interaction and catalytic domains in organ growth control, stem cell self-renewal and tissue regeneration

Cherrett, C., Furutani-Seiki, M. & Bagby, S., 2012, In : Essays in Biochemistry. 53, 1, p. 111-127 17 p.

Research output: Contribution to journalArticle

Open Access
File
Tissue regeneration
Stem cells
Regeneration
Catalytic Domain
Growth
2011
10 Citations (Scopus)
Complement 3d Receptors
Complement Inactivating Agents
X-Rays
Ligands
Complement C3

Graphene-based amperometric and field-effect biosensing with supramolecular protein complexes

Alshammari, A., Posner, M., Jones, G., Upadhyay, A., Bagby, S., Ilie, A. & Estrela, P., 2011.

Research output: Contribution to conferencePoster

Graphite
Proteins
Keto Acids
Oxidoreductases
Dihydrolipoamide Dehydrogenase

Immobilization of E2 protein and its supramolecular complexes, and activity retention on graphene

Alshammari, A., Posner, M., Upadhyay, A., Bagby, S. & Ilie, A., 2011.

Research output: Contribution to conferencePoster

43 Citations (Scopus)

Structural features and ligand binding properties of tandem WW domains from YAP and TAZ, nuclear effectors of the Hippo pathway

Webb, C., Upadhyay, A., Giuntini, F., Eggleston, I., Furutani-Seiki, M., Ishima, R. & Bagby, S., 26 Apr 2011, In : Biochemistry. 50, 16, p. 3300-3309 10 p.

Research output: Contribution to journalArticle

Protein Isoforms
Ligands
Peptides
Protein Interaction Domains and Motifs
Proteins
2010
31 Citations (Scopus)
Complement 3d Receptors
Immune Evasion
Staphylococcus aureus
Mutagenesis
Mutation
5 Citations (Scopus)
71 Downloads (Pure)

Photorhabdus adhesion modification protein (Pam) binds extracellular polysaccharide and alters bacterial attachment

Jones, R. T., Sanchez-Contreras, M., Vlisidou, I., Amos, M. R., Yang, G., Munoz-Berbel, X., Upadhyay, A., Potter, U. J., Joyce, S. A., Ciche, T. A., Jenkins, A. T. A., Bagby, S., ffrench-Constant, R. H. & Waterfield, N. R., 12 May 2010, In : BMC Microbiology. 10, 141.

Research output: Contribution to journalArticle

File
Photorhabdus
Bacterial Polysaccharides
Proteins
Insects
Temperature
2009
14 Citations (Scopus)

A unique lipoylation system in the Archaea: lipoylation in Thermoplasma acidophilum requires two proteins

Posner, M. G., Upadhyay, A., Bagby, S., Hough, D. W. & Danson, M. J., Aug 2009, In : FEBS Journal. 276, 15, p. 4012-4022 11 p.

Research output: Contribution to journalArticle

Thermoplasma
Lipoylation
Archaea
Multienzyme Complexes
Keto Acids

IsaB, a new immunoglobulin-binding protein from Staphylococcus aureus

Clark, E., Upadhyay, A., Bagby, S. & van den Elsen, J., 2009, In : Molecular Immunology. 46, 14, p. 2834-2835 2 p.

Research output: Contribution to journalArticle

2008
89 Citations (Scopus)

Interaction of human complement with Sbi, a staphylococcal immunoglobulin-binding protein: indications of a novel mechanism of complement evasion by Staphylococcus aureus

Burman, J. D., Leung, E., Atkins, K. L., O'Seaghdha, M. N., Lango, L., Bernado, P., Bagby, S., Svergun, D. I., Foster, T. J., Isenman, D. E. & van den Elsen, J. M. H., 20 Jun 2008, In : Journal of Biological Chemistry. 283, 25, p. 17579-17593 15 p.

Research output: Contribution to journalArticle

76 Citations (Scopus)

S. aureus IgG-binding proteins SpA and Sbi: host specificity and mechanisms of immune complex formation

Atkins, K. L., Burman, J. D., Chamberlain, E. S., Cooper, J. E., Poutrel, B., Bagby, S., Jenkins, T. A., Feil, E. J. & van den Elsen, J. M. H., Mar 2008, In : Molecular Immunology. 45, 6, p. 1600-1611 12 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)

Structure-function analysis of the C3 binding region of Staphylococcus aureus immune subversion protein Sbi

Upadhyay, A., Burman, J. D., Clark, E. A., Leung, E., Isenman, D. E., van den Elsen, J. M. H. & Bagby, S., 8 Aug 2008, In : Journal of Biological Chemistry. 283, 32, p. 22113-22120 8 p.

Research output: Contribution to journalArticle

Alternative Complement Pathway
Complement Inactivating Agents
Staphylococcus aureus
Animals
Immune Evasion

Structure–function analysis of the novel Staphylococcus aureus immune subversion protein Sbi

van den Elsen, J., Upadhyay, A., Burman, J., Leung, E., Clark, E., Isenman, D. & Bagby, S., 2008, In : Molecular Immunology. 45, 16, p. 4119 1 p., P71.

Research output: Contribution to journalArticle

19 Citations (Scopus)
2007
30 Citations (Scopus)

Characterisation of receptor binding by the chemotaxis inhibitory protein of Staphylococcus aureus and the effects of the host immune response

Wright, A. J., Higginbottom, A., Philippe, D., Upadhyay, A., Bagby, S., Read, R. C., Monk, P. N. & Partridge, L. J., 2007, In : Molecular Immunology. 44, 10, p. 2507-2517

Research output: Contribution to journalArticle

2005
23 Citations (Scopus)

Evolution of the genetic triplet code via two types of doublet codons

Wu, H-L., Bagby, S. & van den Elsen, J., 2005, In : Journal of Molecular Evolution. 61, 1, p. 54-64

Research output: Contribution to journalArticle

Genetic Code
genetic code
codons
Codon
amino acid
2004
1 Citation (Scopus)

Assignment of the 1H, 13C and 15N resonances of the catalytic domain of guanine nucleotide exchange factor BopE from Burkholderia pseudomallei

Wu, H-L., Williams, C., Upadhyay, A., Galyov, E. E. & Bagby, S., 1 Jun 2004, In : Journal of Biomolecular NMR. 29, 2, p. 215-216

Research output: Contribution to journalArticle

6 Citations (Scopus)

Biophysical characterization of the catalytic domain of guanine nucleotide exchange factor BopE from Burkholderia pseudomallei

Upadhyay, A., Williams, C., Gill, A. C., Philippe, D. L., Davis, K., Taylor, L. A., Stevens, M. P., Galyov, E. E. & Bagby, S., 2004, In : Biochimica Et Biophysica Acta-Proteins and Proteomics. 1698, 1, p. 111-119

Research output: Contribution to journalArticle

14 Citations (Scopus)

Solution structure, backbone dynamics, and interaction with Cdc42 of Salmonella guanine nucleotide exchange factor SopE2

Williams, C., Galyov, E. E. & Bagby, S., 2004, In : Biochemistry. 43, 38, p. 11998-12008

Research output: Contribution to journalArticle

5 Citations (Scopus)

Structural analysis of Salmonella enterica effector protein SopD

Wood, M. W., Williams, C., Upadhyay, A., Gill, A. C., Philippe, D. L., Galyov, E. E., van den Elsen, J. M. H. & Bagby, S., 2004, In : Biochimica Et Biophysica Acta-Proteins and Proteomics. 1698, 2, p. 219-226

Research output: Contribution to journalArticle

2003
1 Citation (Scopus)

Assignment of the 1H, 13C and 15N resonances of the catalytic domain of guanine nucleotide exchange factor SopE2 from Salmonella dublin

Williams, C., Galyov, E. E. & Bagby, S., 1 Jan 2003, In : Journal of Biomolecular NMR. 26, 4, p. 379-380

Research output: Contribution to journalArticle

2002
1 Citation (Scopus)

Protein structure calculation from NMR data

Mal, T. K., Bagby, S. & Ikura, M., 2002, In : Methods in Molecular Biology. 173, p. 267-283

Research output: Contribution to journalArticle

2001
2 Citations (Scopus)

Alternate routes to conformational specificity in a Greek key β barrel protein

Qi, X-F., Bagby, S., Gombos, Z., Ikura, M. & Chakrabartty, A., 1 Sep 2001, In : European Journal of Biochemistry. 268, 17, p. 4653-4664

Research output: Contribution to journalArticle

45 Citations (Scopus)

Optimization of protein solubility and stability for protein nuclear magnetic resonance

Bagby, S., Tong, K. I. & Ikura, M., 2001, In : Methods in Enzymology. 339B, p. 20-41

Research output: Contribution to journalArticle

2000
30 Citations (Scopus)

TFIIA–TAF regulatory interplay: NMR evidence for overlapping binding sites on TBP

Bagby, S., Mal, T. K., Liu, D., Raddatz, E., Nakatani, Y. & Ikura, M., 1 Feb 2000, In : FEBS Letters. 468, 2-3, p. 149-154

Research output: Contribution to journalArticle

1998
20 Citations (Scopus)

Equilibrium folding intermediates of a greek key β-barrel protein

Bagby, S., Go, S., Inouye, S., Ikura, M. & Chakrabartty, A., 1 Feb 1998, In : Journal of Molecular Biology. 276, 3, p. 669-681

Research output: Contribution to journalArticle

39 Citations (Scopus)

Human general transcription factor TFIIB : conformational variability and interaction with VP16 activation domain

Hayashi, F., Ishima, R., Liu, D., Tong, K. I., Kim, S., Reinberg, D., Bagby, S. & Ikura, M., 1 Jun 1998, In : Biochemistry. 37, 22, p. 7941-7951

Research output: Contribution to journalArticle