Projects per year
My lab has interests in several different research areas, including structural biology, protein engineering, biomolecular interactions with 2D materials such as graphene, and nanopore sequencing.
Ongoing research projects include: structure and function of ubiquitin ligase HACE1 (funded by BHF); structure and function of proteins involved in organ size control, stem cell maintenance, and 3D body shape; towards a novel anti-inflammatory, vasculo-protective agent - based on our discovery of a new mode of action of Staphylococcus aureus effector protein Efb involving disruption of host blood cell complexes (funded by BHF); biofunctionalisation of graphene; nanopore sequencing applied to bacterial genome sequencing (Bordetella pertussis), and tumour infiltrating lymphocytes (part funded by Oxford Nanopore Technologies).
I teach on units in all years of the undergraduate degree programmes. This includes BB10003 Biochemistry I, BB10004 Biochemistry II, BB10213 Practical Biochemistry, BB20015 Biochemical Problems and Bioinformatics (convenor), BB20020 Protein Structure, BB30169 Concepts in Systems Biology, BB40048 Enzyme Mechanism and Evolution, BB40085 Medical Biochemistry (convenor), BB40109 Structural Biology in Biotechnology and Medicine.
I also look after the Department's Personal Tutoring System.
1/10/17 → 30/09/20
Project: UK charity
1/05/16 → 30/04/19
Project: UK charity
1/07/14 → 1/12/15
Project: Research-related funding › International Relations Office Funding
1/07/13 → 1/04/14
Project: Research-related funding › Internally Funded Research
Structural, Biochemical and Computational Studies of KIBRA Protein-Protein and Membrane Interactions
1/08/12 → 29/01/16
Project: Research council
Research Output per year
Distinctive phosphoinositide and Ca binding properties of normal and cognitive performance-linked variant forms of KIBRA C2 domainPosner, M. G., Upadhyay, A., Ishima, R., Kalli, A. C., Harris, G., Kremerskothen, J., Sansom, M. S. P., Crennell, S. J. & Bagby, S. 3 May 2018 In : The Journal of biological chemistry.
Research output: Contribution to journal › Article
Research output: Contribution to conference › Poster
Research output: Contribution to conference › Paper