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Personal profile

Research interests

My lab has interests in several different research areas, including structural biology, protein engineering, biosensing, biomolecular interactions with 2D materials such as graphene, and nanopore sequencing.

Ongoing research projects include: research towards a novel anti-inflammatory, vasculo-protective agent - based on our discovery of a new mode of action of Staphylococcus aureus effector protein Efb involving disruption of host blood cell complexes (funded by BHF); autoantibody detection using autoantigen fragments immobilised on gold (funded by Bath Institute for Rheumatic Diseases); investigation of tumour immune landscapes using nanopore sequencing (part funded by Oxford Nanopore Technologies); analysis of protein dynamics at the single molecule level; biofunctionalisation of graphene and other materials; structure and function of proteins involved in organ size control, stem cell maintenance, and 3D body shape.

Teaching interests

I teach on units in all years of the undergraduate degree programmes. This includes BB10003 Biochemistry I, BB10004 Biochemistry II, BB10213 Practical Biochemistry, BB20015 Biochemical Problems and Bioinformatics (convenor), BB20020 Protein Structure, BB30169 Concepts in Systems Biology, BB40048 Enzyme Mechanism and Evolution, BB40085 Medical Biochemistry (convenor), BB40109 Structural Biology in Biotechnology and Medicine.

I also look after the Department's Personal Tutoring System.

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