Projects per year
Personal profile
Research interests
My lab has interests in several different research areas, including structural biology, protein engineering, biosensing, and Nanopore sequencing.
Ongoing research projects include: autoantibody detection; investigation of tumour immune landscapes and clinical metagenomics using Nanopore sequencing (part funded by Oxford Nanopore Technologies); analysis of protein dynamics at the single molecule level; structure and function of proteins; research towards a novel anti-inflammatory, vasculo-protective agent.
Teaching interests
I teach on units in all years of the undergraduate degree programmes. This includes BB10263 Biochemistry, BB10213 Practical Biochemistry, BB20015 Biochemical Problems and Bioinformatics (convenor), BB20020 Protein Structure, BB30169 Concepts in Systems Biology, BB40048 Enzyme Mechanism and Evolution, BB40085 Medical Biochemistry (convenor), BB40109 Structural Biology in Biotechnology and Medicine.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
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Projects
- 8 Finished
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Towards a Novel Anti-Inflammatory Vasculo Protective Agent
Bagby, S. (PI)
1/10/17 → 30/12/20
Project: UK charity
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HACE1 -Substrate Capture Analysis and Activity Enghancement by Deep Mutational Scanning of HACE1
Bagby, S. (PI)
1/05/16 → 31/07/19
Project: UK charity
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Structural, Biochemical and Computational Studies of KIBRA Protein-Protein and Membrane Interactions
Bagby, S. (PI) & Van Den Elsen, J. (CoI)
Biotechnology and Biological Sciences Research Council
1/08/12 → 29/01/16
Project: Research council
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Delivery Fund - GRABA
Bagby, S. (PI) & Ilie, A. (CoI)
Engineering and Physical Sciences Research Council
1/04/12 → 30/06/12
Project: Research council
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Delivery Fund - GRABA
Bagby, S. (PI) & Ilie, A. (CoI)
Engineering and Physical Sciences Research Council
1/04/12 → 31/03/13
Project: Research council
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Double and single stranded detection of 5-methylcytosine and 5-hydroxymethylcytosine with nanopore sequencing
Halliwell, D. O., Honig, F., Bagby, S., Roy, S. & Murrell, A., 15 Feb 2025, In: Communications Biology. 8, 1, 1 p., 243.Research output: Contribution to journal › Article › peer-review
Open Access -
Single Molecule Thermodynamic Penalties Applied to Enzymes by Whispering Gallery Mode Biosensors
Houghton, M. C., Toropov, N. A., Yu, D., Bagby, S. & Vollmer, F., 18 Sept 2024, In: Advanced Science. 11, 35, 2403195.Research output: Contribution to journal › Article › peer-review
Open Access -
Corrigendum to “Generation of murine tumour-reactive T cells by co-culturing murine pancreatic cancer organoids and peripheral blood lymphocytes” (Biochemistry and Biophysics Reports (2022) 32, (S2405580822001650), (10.1016/j.bbrep.2022.101365))
D'Angelo, A., Shibata, K., Tokunaga, M., Furutani-Seiki, M. & Bagby, S., 31 Mar 2023, In: Biochemistry and Biophysics Reports. 33, 101374.Research output: Contribution to journal › Comment/debate › peer-review
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Immune-related pan-cancer gene expression signatures of patient survival revealed by NanoString-based analyses
D'Angelo, A., Kilili, H., Chapman, R., Generali, D., Tinhofer, I., Luminari, S., Donati, B., Ciarrocchi, A., Giannini, R., Moretto, R., Cremolini, C., Pietrantonio, F., Sobhani, N., Bonazza, D., Prins, R., Song, S. G., Jeon, Y. K., Pisignano, G., Cinelli, M. & Bagby, S. & 1 others, , 17 Jan 2023, In: PLoS ONE. 18, 1, e0280364.Research output: Contribution to journal › Article › peer-review
Open Access -
Nanopore-Based Metagenomic Sequencing in Respiratory Tract Infection: A Developing Diagnostic Platform
Chapman, R., Jones, L., D’Angelo, A., Suliman, A., Anwar, M. & Bagby, S., 30 Apr 2023, In: Lung. 201, 2, p. 171-179 9 p.Research output: Contribution to journal › Review article › peer-review
Open AccessFile