Projects per year
Personal profile
Research interests
My lab has interests in several different research areas, including structural biology, protein engineering, biosensing, and Nanopore sequencing.
Ongoing research projects include: autoantibody detection; investigation of tumour immune landscapes and clinical metagenomics using Nanopore sequencing (part funded by Oxford Nanopore Technologies); analysis of protein dynamics at the single molecule level; structure and function of proteins; research towards a novel anti-inflammatory, vasculo-protective agent.
Teaching interests
I teach on units in all years of the undergraduate degree programmes. This includes BB10263 Biochemistry, BB10213 Practical Biochemistry, BB20015 Biochemical Problems and Bioinformatics (convenor), BB20020 Protein Structure, BB30169 Concepts in Systems Biology, BB40048 Enzyme Mechanism and Evolution, BB40085 Medical Biochemistry (convenor), BB40109 Structural Biology in Biotechnology and Medicine.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
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Projects
- 8 Finished
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HACE1 -Substrate Capture Analysis and Activity Enghancement by Deep Mutational Scanning of HACE1
1/05/16 → 31/07/19
Project: UK charity
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Structural, Biochemical and Computational Studies of KIBRA Protein-Protein and Membrane Interactions
Biotechnology and Biological Sciences Research Council
1/08/12 → 29/01/16
Project: Research council
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Delivery Fund - GRABA
Engineering and Physical Sciences Research Council
1/04/12 → 30/06/12
Project: Research council
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Delivery Fund - GRABA
Engineering and Physical Sciences Research Council
1/04/12 → 31/03/13
Project: Research council
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Immune-related pan-cancer gene expression signatures of patient survival revealed by NanoString-based analyses
D'Angelo, A., Kilili, H., Chapman, R., Generali, D., Tinhofer, I., Luminari, S., Donati, B., Ciarrocchi, A., Giannini, R., Moretto, R., Cremolini, C., Pietrantonio, F., Sobhani, N., Bonazza, D., Prins, R., Song, S. G., Jeon, Y. K., Pisignano, G., Cinelli, M., Bagby, S., & 1 others, 17 Jan 2023, In: PLoS ONE. 18, 1, e0280364.Research output: Contribution to journal › Article › peer-review
Open Access -
Nanopore-Based Metagenomic Sequencing in Respiratory Tract Infection: A Developing Diagnostic Platform
Chapman, R., Jones, L., D’Angelo, A., Suliman, A., Anwar, M. & Bagby, S., 30 Apr 2023, In: Lung. 201, 2, p. 171-179 9 p.Research output: Contribution to journal › Review article › peer-review
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A peptide from the staphylococcal protein Efb binds P-selectin and inhibits the interaction of platelets with leukocytes
Wallis, S., Wolska, N., Englert, H., Posner, M., Upadhyay, A., Renne, T., Eggleston, I., Bagby, S. & Pula, G., 31 Mar 2022, In: Journal of Thrombosis and Haemostasis. 20, 3, p. 729-741 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Citations (SciVal)30 Downloads (Pure) -
Comparative genomics of Bordetella pertussis isolates from New Zealand, a country with an uncommonly high incidence of whooping cough.
Ring, N., Davies, H., Morgan, J., Sundaresan, M., Tiong, A., Preston, A. & Bagby, S., 27 Jan 2022, In: Microbial Genomics. 8, 1, 29 p., MGEN-D-21-00373R1.Research output: Contribution to journal › Article › peer-review
Open Access -
Generation of murine tumour-reactive T cells by co-culturing murine pancreatic cancer organoids and peripheral blood lymphocytes
D'Angelo, A., Shibata, K., Tokunaga, M., Furutani-Seiki, M. & Bagby, S., 31 Dec 2022, In: Biochemistry and Biophysics Reports. 32, 101365.Research output: Contribution to journal › Article › peer-review
Open Access