Simon is a BBSRC Research Fellow at the University of Bath. With research interests including biocatalysis, peptide drug discovery and directed evolution, his current work aims to develop a bio-based systems for sustainable cyclic peptide production for drug discovery.

Before his fellowship, Simon was a research associate working with Jody Mason at the University of Bath where he used genetically encoded library screening to identify peptide antagonists to modulate protein-protein interactions to develop peptide-based cancer therapeutics by targeting transcription factors which are historically considered undruggable. Prior to joining the University of Bath, Simon acquired significant experience in enzymology and biocatalysis through his PhD research working with a peptide asparaginyl ligase in the lab of Louis Luk at Cardiff University.