Projects per year
Personal profile
Research interests
Dr Hussain was awarded a PhD in Medical and Molecular Genetics from Guy’s Hospital, King’s College London, before completing his postdoctoral training at the University of Cambridge. His current research aims to understand how aspects of transcriptome malleability can shape biological outcomes such as those associated with inherited neurodevelopmental disorders. Molecular investigations in his laboratory currently centre on developing and applying Next Generation DNA/RNA Sequencing-based methodologies, while relevant transgenic models are employed for physiological in vivo studies.
Fingerprint Dive into the research topics where Shobbir Hussain is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
RNA
Medicine & Life Sciences
Transcriptome
Medicine & Life Sciences
Cytosine
Medicine & Life Sciences
RNA Sequence Analysis
Medicine & Life Sciences
Methylation
Medicine & Life Sciences
DNA Sequence Analysis
Medicine & Life Sciences
Nucleotides
Medicine & Life Sciences
Immunoprecipitation
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects 2015 2019
- 4 Finished
Long-read Nanopore Sequencing to Identify Isoform-Specific Patterns of mRNA Methylation
15/01/18 → 14/01/19
Project: Research council
Nanopores
Methylation
Protein Isoforms
RNA
Messenger RNA
Characterising the Epitanscriptome Using Catalysis-Dependent RIPseq Approaches
1/04/16 → 31/08/19
Project: Research council
Catalysis
RNA
Research
DNA
RNA Sequence Analysis
Characterizing the Landscape and Function of the Epitranscriptome using Catalysis-Dependent RIP-seq Approaches
23/03/15 → 22/03/16
Project: Research council
Research Output 2002 2019
A comprehensive examination of Nanopore native RNA sequencing for characterization of complex transcriptomes
Soneson, C., Yao, Y., Bratus-Neuenschwander, A., Patrignani, A., Robinson, M. D. & Hussain, M. S., 31 Jul 2019, In : Nature Communications. 10, 1, p. 1-14 14 p., 3359.Research output: Contribution to journal › Article
Open Access
5
Citations
(Scopus)
A junction coverage compatibility score to quantify the reliability of transcript abundance estimates and annotation catalogs
Soneson, C., Love, M. I., Patro, R., Hussain, M. S., Malhotra, D. & Robinson, M. D., 1 Feb 2019, In : Life Science Alliance. 2, 1, e201800175.Research output: Contribution to journal › Article
Open Access
1
Citation
(Scopus)
3
Downloads
(Pure)
Catalytic crosslinking-based methods for enzyme-specified profiling of RNA ribonucleotide modifications
Hussain, M. S., 1 Mar 2019, In : Methods. 156, p. 60-65 6 p.Research output: Contribution to journal › Article
Open Access
File
FICC-Seq: a method for enzyme-specified profiling of methyl-5-uridine in cellular RNA
Carter, J-M., Emmett, W., Rdl Mozos, I., Kotter, A., Helm, M., Ule, J. & Hussain, M. S., 4 Nov 2019, In : Nucleic Acids Research. 47, 19, p. 1-12 12 p., gkz658.Research output: Contribution to journal › Article
Open Access
3
Citations
(Scopus)
13
Downloads
(Pure)
Native RNA-Sequencing Throws its Hat into the Transcriptomics Ring
Hussain, S., 1 Apr 2018, In : Trends in Biochemical Sciences. 43, 4, p. 225-227 3 p.Research output: Contribution to journal › Review article
Open Access
File
RNA Sequence Analysis
Transcriptome
RNA
DNA
Chemical analysis
Thesis
Investigation into the role of the RNA methyltransferase NSun2 in neuroplasticity regulation
Author: George, H., 2 Oct 2019Supervisor: Williams, R. J. (Supervisor) & Hussain, M. S. (Supervisor)
Student thesis: Doctoral Thesis › PhD
File