Shobbir Hussain

Dr

  • 4 SOUTH 1.32

20022020

Research output per year

If you made any changes in Pure these will be visible here soon.

Personal profile

Research interests

Dr Hussain was awarded a PhD in Medical and Molecular Genetics from Guy’s Hospital, King’s College London, before completing his postdoctoral training at the University of Cambridge. His current research aims to understand how aspects of transcriptome malleability can shape biological outcomes such as those associated with inherited neurodevelopmental disorders. Molecular investigations in his laboratory currently centre on developing and applying Next Generation DNA/RNA Sequencing-based methodologies, while relevant transgenic models are employed for physiological in vivo studies.

Fingerprint Dive into the research topics where Shobbir Hussain is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects

  • Research Output

    On a new proposed mechanism of 5-fluorouracil-mediated cytotoxicity

    Hussain, S., 13 Mar 2020, In : Trends in Cancer.

    Research output: Contribution to journalArticle

    FICC-Seq: a method for enzyme-specified profiling of methyl-5-uridine in cellular RNA

    Carter, J-M., Emmett, W., Rdl Mozos, I., Kotter, A., Helm, M., Ule, J. & Hussain, S., 4 Nov 2019, In : Nucleic Acids Research. 47, 19, p. e113-e124 12 p., gkz658.

    Research output: Contribution to journalArticle

    Open Access
    3 Citations (Scopus)

    A comprehensive examination of Nanopore native RNA sequencing for characterization of complex transcriptomes

    Soneson, C., Yao, Y., Bratus-Neuenschwander, A., Patrignani, A., Robinson, M. D. & Hussain, S., 31 Jul 2019, In : Nature Communications. 10, 1, p. 1-14 14 p., 3359.

    Research output: Contribution to journalArticle

    Open Access
    4 Citations (Scopus)

    Robust long-read native DNA sequencing using the ONT CsgG Nanopore system

    Carter, J-M. & Hussain, S., 2017, In : Wellcome Open Research. 2, 23.

    Research output: Contribution to journalArticle

    Open Access
  • 13 Citations (Scopus)

    Deficient methylation and formylation of mt-tRNAMet wobble cytosine in a patient carrying mutations in NSUN3

    Van Haute, L., Dietmann, S., Kremer, L., Hussain, S., Pearce, S. F., Powell, C. A., Rorbach, J., Lantaff, R., Blanco, S., Sauer, S., Kotzaeridou, U., Hoffmann, G. F., Memari, Y., Kolb-Kokocinski, A., Durbin, R., Mayr, J. A., Frye, M., Prokisch, H. & Minczuk, M., 30 Jun 2016, In : Nature Communications. 7, p. 1-10 10 p., 12039.

    Research output: Contribution to journalArticle

    Open Access
  • 60 Citations (Scopus)
    74 Downloads (Pure)

    Thesis

    Investigation into the role of the RNA methyltransferase NSun2 in neuroplasticity regulation

    Author: George, H., 2 Oct 2019

    Supervisor: Williams, R. J. (Supervisor) & Hussain, M. S. (Supervisor)

    Student thesis: Doctoral ThesisPhD

    File