Projects per year
Personal profile
Research interests
Dr Hussain was awarded a PhD in Medical and Molecular Genetics from Guy’s Hospital, King’s College London, before completing his postdoctoral training at the University of Cambridge. His current research aims to understand how aspects of transcriptome malleability can shape biological outcomes such as those associated with inherited neurodevelopmental disorders. Molecular investigations in his laboratory currently centre on developing and applying Next Generation DNA/RNA Sequencing-based methodologies, while relevant transgenic models are employed for physiological in vivo studies.
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- 3 Similar Profiles
RNA
Medicine & Life Sciences
Transcriptome
Medicine & Life Sciences
Cytosine
Medicine & Life Sciences
RNA Sequence Analysis
Medicine & Life Sciences
Methylation
Medicine & Life Sciences
DNA Sequence Analysis
Medicine & Life Sciences
Nucleotides
Medicine & Life Sciences
Immunoprecipitation
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects 2015 2019
Long-read Nanopore Sequencing to Identify Isoform-Specific Patterns of mRNA Methylation
15/01/18 → 14/01/19
Project: Research council
Nanopores
Methylation
Protein Isoforms
RNA
Messenger RNA
Characterising the Epitanscriptome Using Catalysis-Dependent RIPseq Approaches
1/04/16 → 31/08/19
Project: Research council
Catalysis
RNA
Research
DNA
RNA Sequence Analysis
Characterizing the Landscape and Function of the Epitranscriptome using Catalysis-Dependent RIP-seq Approaches
23/03/15 → 22/03/16
Project: Research council
Research Output 2002 2018
Native RNA-Sequencing Throws its Hat into the Transcriptomics Ring
Hussain, S. 1 Apr 2018 In : Trends in Biochemical Sciences. 43, 4, p. 225-227 3 p.Research output: Contribution to journal › Review article
RNA Sequence Analysis
Transcriptome
RNA
DNA
Chemical analysis
1
Citations
Illustrating the Epitranscriptome at Nucleotide Resolution Using Methylation-iCLIP (miCLIP)
George, H., Ule, J. & Hussain, S. 28 Mar 2017 In : Methods in Molecular Biology. 1562, p. 91-106 16 p.Research output: Contribution to journal › Article
Methylation
Nucleotides
RNA
Cytosine
Transcriptome
6
Citations
Robust long-read native DNA sequencing using the ONT CsgG Nanopore system
Carter, J-M. & Hussain, S. 2017 In : Wellcome Open Research. 2, 23Research output: Contribution to journal › Article
Open Access
Nanopores
DNA Sequence Analysis
Technology
DNA
Throughput
Shaping and Reshaping Transcriptome Plasticity During Evolution
Hussain, S. Sep 2017 In : Trends in Biochemical Sciences. 42, 9, p. 682-684Research output: Contribution to journal › Article
Open Access
File
Transcriptome
Plasticity
Protein Isoforms
RNA
Biodiversity
32
Citations
Deficient methylation and formylation of mt-tRNAMet wobble cytosine in a patient carrying mutations in NSUN3
Van Haute, L., Dietmann, S., Kremer, L., Hussain, S., Pearce, S. F., Powell, C. A., Rorbach, J., Lantaff, R., Blanco, S., Sauer, S., Kotzaeridou, U., Hoffmann, G. F., Memari, Y., Kolb-Kokocinski, A., Durbin, R., Mayr, J. A., Frye, M., Prokisch, H. & Minczuk, M. 30 Jun 2016 In : Nature Communications. 7, 12039Research output: Contribution to journal › Article
Open Access
File
RNA, Transfer, Met
ribonucleic acids
methionine
methylation
Methylation