Projects per year
Personal profile
Research interests
Dr Hussain was awarded a PhD in Medical and Molecular Genetics from King’s College London before completing his postdoctoral training at the University of Cambridge. His current research aims to understand how aspects of transcriptome malleability can shape biological outcomes such as those associated with inherited neurodevelopmental disorders. Molecular investigations in his laboratory currently centre on developing and applying next generation DNA/RNA sequencing-based methodologies, while relevant transgenic models are employed for physiological in vivo studies.
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Projects
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Investigating the role of Nsun6 methyltransferase during zebrafish brain development
Nikolaou, N., Hussain, S. & Kelsh, R.
25/02/20 → …
Project: Research-related funding
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Long-read Nanopore Sequencing to Identify Isoform-Specific Patterns of mRNA Methylation
Biotechnology and Biological Sciences Research Council
15/01/18 → 14/01/19
Project: Research council
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Characterising the Epitanscriptome Using Catalysis-Dependent RIPseq Approaches
Biotechnology and Biological Sciences Research Council
1/04/16 → 31/08/19
Project: Research council
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Characterizing the Landscape and Function of the Epitranscriptome using Catalysis-Dependent RIP-seq Approaches
23/03/15 → 22/03/16
Project: Research council
Research Output
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On a new proposed mechanism of 5-fluorouracil-mediated cytotoxicity
Hussain, S., 1 May 2020, In: Trends in Cancer. 6, 5, p. 365-368 4 p.Research output: Contribution to journal › Review article › peer-review
1 Citation (Scopus) -
FICC-Seq: a method for enzyme-specified profiling of methyl-5-uridine in cellular RNA
Carter, J-M., Emmett, W., Rdl Mozos, I., Kotter, A., Helm, M., Ule, J. & Hussain, S., 4 Nov 2019, In: Nucleic Acids Research. 47, 19, p. e113-e124 12 p., gkz658.Research output: Contribution to journal › Article › peer-review
Open Access7 Citations (Scopus) -
A comprehensive examination of Nanopore native RNA sequencing for characterization of complex transcriptomes
Soneson, C., Yao, Y., Bratus-Neuenschwander, A., Patrignani, A., Robinson, M. D. & Hussain, S., 31 Jul 2019, In: Nature Communications. 10, 1, p. 1-14 14 p., 3359.Research output: Contribution to journal › Article › peer-review
Open Access23 Citations (Scopus) -
Native RNA-Sequencing Throws its Hat into the Transcriptomics Ring
Hussain, S., 1 Apr 2018, In: Trends in Biochemical Sciences. 43, 4, p. 225-227 3 p.Research output: Contribution to journal › Review article › peer-review
Open AccessFile5 Citations (Scopus)41 Downloads (Pure) -
Robust long-read native DNA sequencing using the ONT CsgG Nanopore system
Carter, J-M. & Hussain, S., 2017, In: Wellcome Open Research. 2, 23.Research output: Contribution to journal › Article › peer-review
Open Access19 Citations (Scopus)