Sergey Smirnov

Search results

• 2024

  Ex-vivo systems for neuromodulation: A comparison of ex-vivo and in-vivo large animal nerve electrophysiology

  Ribeiro, M., Andreis, F. R., Jabban, L., Nielsen, T. G. N. D., Smirnov, S. V., Lutteroth, C., Proulx, M. J., Rocha, P. R. F. & Metcalfe, B., 30 Jun 2024, In: Journal of Neuroscience Methods. 406, 110116.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • In Vivo 100%
  • Electrophysiology 100%
  • Neuromodulation 100%
  • Regression Analysis 22%
  • Ulnar Nerve 22%
  1 Downloads (Pure)
• 2018

  Enhanced calcium entry via activation of NOX/PKC underlies increased vasoconstriction induced by methylglyoxal

  Eid, B. G., Sharib, A. A., El-bassossy, H. M., Balamash, K. & Smirnov, S., 2 Dec 2018, In: Biochemical and Biophysical Research Communications. 506, 4, p. 1013-1018 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Aortic Constriction 100%
  • Diabetic Complication 50%
  12 Citations (SciVal)

  81 Downloads (Pure)
• 2015

  Sphingosylphosphorylcholine potentiates vasoreactivity and voltage-gated Ca2+ entry via NOX1 and reactive oxygen species

  Shaifta, Y., Snetkov, V. A., Prieto-Lloret, J., Knock, G. A., Smirnov, S. V., Aaronson, P. I. & Ward, J. P. T., 1 Apr 2015, In: Cardiovascular Research. p. 121-130

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Sphingosylphosphorylcholine 100%
  • NOX1 100%
  • Tempol 33%
  • U46619 25%
  • 1 [[6 (3 Methoxyestra 1,3,5(10) Trien 17beta Yl)amino]hexyl] 1h Pyrrole 2,5 Dione 11%
  16 Citations (SciVal)

  195 Downloads (Pure)

• TRPM4 inhibitor 9-phenanthrol activates endothelial cell intermediate conductance calcium-activated potassium channels in rat isolated mesenteric artery

  Garland, C. J., Smirnov, S., Bagher, P., Lim, C., Huang, C. Y., Mitchell, R., Stanley, C., Pinkney, A. & Dora, K. A., Feb 2015, In: British Journal of Pharmacology. 172, 4, p. 1114-1123 10 p.

  Research output: Contribution to journal › Article › peer-review

  File

  • Intermediate Conductance Calcium Activated Potassium Channel 100%
  • Transient Receptor Potential Melastatin 100%
  • Transient Receptor Potential Channel M4 100%
  • Muscle Fiber Membrane Steady Potential 12%
  • Antibody Labeling 12%
  40 Citations (SciVal)

  208 Downloads (Pure)
• 2013

  Voltage-activated Ca²⁺ channels in rat renal afferent and efferent myocytes: no evidence for the T-type Ca²⁺ current

  Smirnov, S. V., Loutzenhizer, K. & Loutzenhiser, R., 1 Feb 2013, In: Cardiovascular Research. 97, 2, p. 293-301 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Myocyte 100%
  • Calcium Channel 100%
  • Arteriole 66%
  • Efferent Arteriole 50%
  • Inactivation 33%
  17 Citations (SciVal)

  186 Downloads (Pure)

• β₁-adrenoceptor stimulation suppresses endothelial IK_Ca-channel hyperpolarization and associated dilatation in resistance arteries

  Iarova, P. L., Smirnov, S. V., Dora, K. A. & Garland, C. J., Jun 2013, In: British Journal of Pharmacology. 169, 4, p. 875-886 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Beta Adrenergic Receptor 100%
  • Beta 1 Adrenergic Receptor 49%
  13 Citations (SciVal)

  171 Downloads (Pure)
• 2011

  Segment-specific differences in the inward rectifier K⁺ current along the renal interlobular artery.

  Chilton, L., Smirnov, S. V., Loutzenhiser, K., Wang, X. & Loutzenhiser, R., 1 Oct 2011, In: Cardiovascular Research. 92, 1, p. 169-177 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Interlobular Arteries 100%
  • Potassium Current 100%
  • Potassium Ion 100%
  • Arteriole 50%
  • Vessel Diameter 25%
  18 Citations (SciVal)

  190 Downloads (Pure)

• Superoxide differentially controls pulmonary and systemic vascular tone through multiple signalling pathways

  Snetkov, V. A., Smirnov, S. V., Kua, J., Aaronson, P. I., Ward, J. P. T. & Knock, G. A., Jan 2011, In: Cardiovascular Research. 89, 1, p. 214-224 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Calcium Ion 100%
  • Superoxide 100%
  • Blood Vessel Tone 100%
  • Pulmonary Artery 83%
  • Ligation 83%
  24 Citations (SciVal)
• 2010

  Calcium-dependent regulation of voltage-gated sodium channels in cardiac myocytes: just the beginning?

  Yuill, K. H. & Smirnov, S. V., 2010, In: Cardiovascular Research. 85, 3, p. 411-412 2 p.

  Research output: Contribution to journal › Article › peer-review
  4 Citations (SciVal)

• Single protein molecule mapping with magnetic atomic force microscopy

  Moskalenko, A. V., Yarova, P. L., Gordeev, S. N. & Smirnov, S. V., 3 Feb 2010, In: Biophysical Journal. 98, 3, p. 478-487 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Atomic Force Microscopy 100%
  • Protein 100%
  • Molecule 100%
  • Microscopy 100%
  • Magnetism 100%
  16 Citations (SciVal)
• 2009

  An atomic force microscope nanoscalpel for nanolithography and biological applications

  Beard, J. D., Burbridge, D. J., Moskalenko, A. V., Dudko, O., Yarova, P. L., Smirnov, S. V. & Gordeev, S. N., 2009, In: Nanotechnology. 20, 44, 445302.

  Research output: Contribution to journal › Article › peer-review

  • Nanolithography 100%
  • Devices 100%
  • Electrode 100%
  • Nanoelectronics 33%
  • Nanotools 33%
  15 Citations (SciVal)

• Cellular localization of mitochondria contributes to K_v channel-mediated regulation of cellular excitability in pulmonary but not mesenteric circulation

  Firth, A. L., Gordienko, D. V., Yuill, K. H. & Smirnov, S. V., Mar 2009, In: American Journal of Physiology-Lung Cellular and Molecular Physiology. 296, 3, p. L347-L360

  Research output: Contribution to journal › Article › peer-review

  • Mesentery Blood Flow 100%
  • Arterial Smooth Muscle Cell 50%
  • Hypoxic Pulmonary Vasoconstriction 25%
  • Antimycin A1 25%
  • Antimycin A 25%
  29 Citations (SciVal)

• Structural and functional association between mitochondria and voltage-gated K+ currents in the rat pulmonary (PAMs), but not mesenteric (MAMs) arterial myocytes

  Smirnov, S. V., Gordienko, D. V., Firth, A. L. & Yuill, K. H., 2009, In: FASEB Journal. 23, p. 999.7

  Research output: Contribution to journal › Article

  4 Citations (SciVal)

• Voltage-independent calcium channels mediate lipopolysaccharide-induced hyporeactivity to endothelin-1 in the rat aorta

  El-Awady, M. S. H., Smirnov, S. V. & Watson, M. L., 2009, In: American Journal of Physiology-Heart and Circulatory Physiology. 296, 5, p. H1408-H1415

  Research output: Contribution to journal › Article › peer-review
  7 Citations (SciVal)
• 2008

  Desensitization of the soluble guanylyl cyclase/cGMP pathway by lipopolysaccharide in rat isolated pulmonary artery but not aorta

  El-Awady, M. S. H., Smirnov, S. V. & Watson, M. L., 2008, In: British Journal of Pharmacology. 155, 8, p. 1164-1173 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Lipopolysaccharide 100%
  • Cyclic GMP 100%
  • Phosphodiesterase V 50%
  • 4 Amino 5 Cyclopropyl 2 [1 (2 Fluorobenzyl) 1h pyrazolo[3,4 B]pyridin 3 Yl]pyrimidine 37%
  • N [3 (Aminomethyl)benzyl]acetamidine 25%
  15 Citations (SciVal)

• Involvement of Na+-H+ exchanger in hypoxia-mediated inhibition of voltage-gated K+ channels in rat small pulmonary arterial myocytes

  Smirnov, S. V., Telezhkin, V. S., Firth, A. L. & Yuill, K. H., 2008, In: Fundamental & Clinical Pharmacology. 22, Suppl 2, p. 63 1 p.

  Research output: Contribution to journal › Article › peer-review

• Lipopolysaccharide-induced vascular hypocontractility to endothelin-1 in rats is dependent on non-voltage-gated calcium channels but not on calcium sensitization

  El-Awady, M. S. H., Smirnov, S. V. & Watson, M. L., 2008, In: Fundamental & Clinical Pharmacology. 22, Suppl 2, p. 74 1 p.

  Research output: Contribution to journal › Article › peer-review

• Mitochondria-dependent regulation of Kv currents in rat pulmonary artery smooth muscle cells

  Firth, A. L., Yuill, K. H. & Smirnov, S. V., Jul 2008, In: American Journal of Physiology-Lung Cellular and Molecular Physiology. 295, 1, p. L61-L70 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Pulmonary Artery Smooth Muscle Cell 100%
  • Pulmonary Artery 100%
  • Antimycin A 100%
  • Arterial Smooth Muscle Cell 50%
  • Pulmonary Vasculature 50%
  22 Citations (SciVal)
• 2007

  Biophysical characterisation of an extracellular calcium-dependent non-selective cation current (Ic) in rat small pulmonary arterial myocytes

  Yuill, K. H. & Smirnov, S. V., 2007, In: Biophysical Journal. 92, Suppl S, p. 120A-120A

  Research output: Contribution to journal › Article › peer-review
• 2006

  Mechanisms of LPS-induced changes in vascular reactivity to endothelin 1 in rat aortic and pulmonary vessels

  El-Awady, M. S., Smirnov, S. V. & Watson, M. L., 2006, In: pA2Online. 4, 2, p. 020P

  Research output: Contribution to journal › Article › peer-review
• 2005

  Effect of extracellular Na⁺ removal and amiloride on voltage-gated K⁺ channel currents I_Kv in rat small (resistance) pulmonary arterial myocytes (PAMs)

  Smith, A. L., Yuill, K. H. & Smirnov, S. V., 2005, In: Biophysical Journal. 88, 1, p. 305A-305A

  Research output: Contribution to journal › Article › peer-review

• Effects of H2O2 on Kv currents in rat pulmonary arterial myocytes (PAMs): the role of intracellular redox state

  Smith, A. L., Yuill, K. H. & Smirnov, S. V., 2005, In: pA2Online. 3, 2, p. 125P

  Research output: Contribution to journal › Article › peer-review

• Effects of intracellular magnesium on Kv1.5 and Kv2.1 potassium channels

  Tammaro, P., Smirnov, S. V. & Moran, O., 2005, In: European Biophysics Journal. 34, 1, p. 42-51 10 p.

  Research output: Contribution to journal › Article › peer-review

  11 Citations (SciVal)

• Modulation of the voltage-dependent K + current by intracellular Mg 2+ in rat aortic smooth muscle cells

  Tammaro, P., Smith, A. L., Crowley, B. L. & Smirnov, S. V., 2005, In: Cardiovascular Research. 65, 2, p. 387-396 10 p.

  Research output: Contribution to journal › Article › peer-review

  27 Citations (SciVal)

• Voltage-gated K+ (Kv) channel currents in mouse intrapulmonary and mesenteric arteries

  Smirnov, S. V. & Smith, A. L., 2005, In: Biophysical Journal. 88, 1, p. 304A-305A

  Research output: Contribution to journal › Article › peer-review
• 2004

  Effect of intracellular magnesium on K-v currents in rat conduit pulmonary arterial myocytes (rPAMs) and K-v channels expressed in Xenopus oocytes

  Tammaro, P., Moran, O., Conti, F. & Smirnov, S. V., 2004, In: Biophysical Journal. 86, 1, p. 391A-391A

  Research output: Contribution to journal › Article › peer-review

• Pharmacological evidence for a key role of voltage-gated K ⁺ channels in the function of rat aortic smooth muscle cells

  Smirnov, S. V., Tammaro, P., Smith, A. L. & Hutchings, S. R., 2004, In: pA2Online. 2, 2, 010P.

  Research output: Contribution to journal › Article › peer-review

• Pharmacological evidence for a key role of voltage-gated K + channels in the function of rat aortic smooth muscle cells

  Tammaro, P., Smith, A. L., Hutchings, S. R. & Smirnov, S. V., Sept 2004, In: British Journal of Pharmacology. 143, 2, p. 303-317 15 p.

  Research output: Contribution to journal › Article › peer-review
  48 Citations (SciVal)

• The effect of organ culture and endothelin-1 treatment on Kv currents in rat small pulmonary arterial myocyte

  Smith, A. L. & Smirnov, S. V., 2004, In: pA2Online. 2, 2, 012P.

  Research output: Contribution to journal › Article
• 2003

  Modulation of the voltage-gated potassium (Kv) channel currents by physiological concentrations of intracellular Mg2+ in rat aortic smooth muscle cells (RASMCs)

  Tammaro, P. & Smirnov, S. V., 2003, In: Journal of Physiology. 547P, p. C47

  Research output: Contribution to journal › Article › peer-review

• Modulation of the voltage-gates potassium (Kv) channel currents by intracellular Mg2+ in rat vascular smooth muscle cells (VSMCs)

  Tammaro, P. & Smirnov, S. V., 2003, In: Biophysical Journal. 84, 2

  Research output: Contribution to journal › Article › peer-review

• Role of voltage-gates K+(KV) channels in vascular function

  Smirnov, S. V., Tammaro, P., Hutchings, S. R. & Smith, A. L., 2003, In: Neurophysiology. 35, 3/4, p. 262-275 14 p.

  Research output: Contribution to journal › Article › peer-review

  6 Citations (SciVal)
• 2002

  Developmental changes in the functional characteristics and expression of voltage-gated K + channel currents in rat aortic myocytes

  Belevych, A. E., Beck, R., Tammaro, P., Poston, L. & Smirnov, S. V., 2002, In: Cardiovascular Research. 54, 1, p. 152-161 10 p.

  Research output: Contribution to journal › Article › peer-review

  25 Citations (SciVal)

• Electrophysiologically distinct smooth muscle cell subtypes in rat conduit and resistance pulmonary arteries

  Smirnov, S. V., Beck, R., Tammaro, P., Ishii, T. & Aaronson, P. I., 2002, In: The Journal of Physiology. 538, 3, p. 867-878 12 p.

  Research output: Contribution to journal › Article › peer-review

  58 Citations (SciVal)

• Modulation of cell membrane capacitance by arachidonic acid in rat aortic myocytes

  Smirnov, S. V. & Beck, R., 2002, In: Biophysical Journal. 82, 1 Pt.2, p. 285A

  Research output: Contribution to journal › Article › peer-review

• Modulation of Kv channel currents by bisindolylmaleimide I (BIM), a selective PKC, inhibitor, in rat aortic myocytes

  Tammaro, P. & Smirnov, S. V., 2002, In: Biophysical Journal. 82, 1 Pt 2, p. 285A

  Research output: Contribution to journal › Article › peer-review

• Modulation of the native kV2.1 channel by phosphorylation in rat aortic myocytes

  Tammaro, P., Aaronson, P. I. & Smirnov, S. V., 2002, In: Biophysical Journal. 80, 1 Pt 1, p. 440a

  Research output: Contribution to journal › Article › peer-review
• 2001

  Differing voltage-gated K + currents in rat conduit and resistance pulmonary arteries

  Smirnov, S. V., Beck, R., Tammaro, P. & Aaronson, P. I., 2001, In: Biophysical Journal. 80, 1 Pt 2, p. 214a

  Research output: Contribution to journal › Article › peer-review

• Tamoxifen activates smooth muscle BK channels through the regulatory β1 subunit

  Dick, G. M., Rossow, C. F., Smirnov, S. V., Horowitz, B. & Sanders, K. M., 2001, In: Journal of Biological Chemistry. 276, 37, p. 34594-34599 6 p.

  Research output: Contribution to journal › Article › peer-review

  117 Citations (SciVal)
• 2000

  Evidence for two populations of cells with different voltage-gated K⁺ currents in rat conduit pulmonary arteries

  Smirnov, S. V., Beck, R. & Aaronson, P. I., 2000, In: The Journal of Physiology. 526, p. 132P-133P

  Research output: Contribution to journal › Article

• Mechanism of effect of extracellular pH on L-type Ca2+ channel currents in human mesenteric arterial cells

  Smirnov, S. V., Knock, G. A., Belevych, A. E. & Aaronson, P. I., 2000, In: American Journal of Physiology-Heart and Circulatory Physiology. 279, 1, p. H76-H85

  Research output: Contribution to journal › Article › peer-review

  • Acidification 100%
  • Alkalinization 100%
  • Inactivation 74%
  • Vasoconstriction 49%
  • Voltage-Gated Calcium Channels 49%
  22 Citations (SciVal)

• Mechanism of modulation of the L-type Ca2+ channel currents by extracellular pH in single human mesenteric arterial cells

  Smirnov, S. V., Knock, A. G., Belevych, A. E. & Aaronson, P. I., 2000, In: Biophysical Journal. 78, p. 457A

  Research output: Contribution to journal › Article › peer-review