Projects per year
Personal profile
Research interests
My research is broadly concerned with developing economically efficient scale-up systems for cell therapy manufacturing. I design and compare different bioreactor configurations for the culture and manufacturing of cell and cell-derived products. Currently, I focus on production of red blood cells from an immortalized blood progenitor cell line (Bristol Erythroid Lineage- Adult; BELA cells) and will also be working towards developing systems for production of stem cell-derived therapeutic extracellular vesicles.
Willing to supervise PhD
I welcome enquiries from potential PhD students in the areas of regenerative medicine, in particular bioprocess engineering.
Education/Academic qualification
Biomedical Engineering, Doctor of Philosophy, Keele University
Keywords
- Bioreactors
- Regenerative medicine
- Extracellular vesicles
- Blood Manufacturing
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Projects
Developing a combined isolation and size-sorting tool for ovarian cancerous exosome detection.
13/01/20 → 13/06/20
Project: Research-related funding
Nanoengineered membranes for the separation of extracellular vesicles
4/02/19 → 18/04/19
Project: Other
Fluidised Bed Bioreactor for Culturing Extracellular Vesicle-Secreting Cells
1/02/19 → 1/05/19
Project: Research-related funding
Research Output
Fluidized bed bioreactor for the potential scale-up of an adult erythroid cell line
Moise, S., Pellegrin, S., Frayne, J., Toye, A. M. & Ellis, M., 2019.Research output: Contribution to conference › Poster
Fluidized Bed Bioreactor for the potential scale-up of an adult erythroid cell line
Moise, S., Pellegrin, S., Frayne, J., Toye, A. M. & Ellis, M., 2019.Research output: Contribution to conference › Poster
The potential of magnetic hyperthermia for triggering the differentiation of cancer cells
Moise, S., Byrne, J. M., El Haj, A. J. & Telling, N. D., 28 Nov 2018, In : Nanoscale. 10, 44, p. 20519-20525 7 p.Research output: Contribution to journal › Article
Open Access
File
8
Citations
(Scopus)
34
Downloads
(Pure)
The cellular magnetic response and biocompatibility of biogenic zinc- and cobalt-doped magnetite nanoparticles
Moise, S., Céspedes, E., Soukup, D., Byrne, J. M., El Haj, A. J. & Telling, N. D., 3 Jan 2017, In : Scientific Reports. 7, 39922.Research output: Contribution to journal › Article
Open Access
28
Citations
(Scopus)
In situ measurement of magnetization relaxation of internalized nanoparticles in live cells
Soukup, D., Moise, S., Céspedes, E., Dobson, J. & Telling, N. D., 27 Jan 2015, In : ACS Nano. 9, 1, p. 231-240 10 p.Research output: Contribution to journal › Article
65
Citations
(Scopus)