Projects per year
Personal profile
Research interests
My research is broadly concerned with developing economically efficient scale-up systems for cell therapy manufacturing. I design and compare different bioreactor configurations for the culture and manufacturing of cell and cell-derived products. Currently, I focus on production of red blood cells from an immortalized blood progenitor cell line (Bristol Erythroid Lineage- Adult; BELA cells) and will also be working towards developing systems for production of stem cell-derived therapeutic extracellular vesicles.
Willing to supervise doctoral students
I welcome enquiries from potential PhD students in the areas of regenerative medicine, in particular bioprocess engineering.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Biomedical Engineering, Doctor of Philosophy, An evaluation of tailored magnetic nanoparticles in the induction of stem cell differentiation, Keele University
Keywords
- Bioreactors
- Regenerative medicine
- Extracellular vesicles
- Blood Manufacturing
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Manufacturing in Hospital: BioMed 4.0
Leese, H. (PI), Castro Dominguez, B. (CoI), Flynn, J. (CoI), Gill, R. (CoI), Martinez Hernandez, U. (CoI), Moise, S. (CoI) & Wilson, P. (CoI)
Engineering and Physical Sciences Research Council
2/11/21 → 29/08/25
Project: Research council
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EPSRC IAA - Fluidised bed bioreactors for large-scale manufacture of mammalian single cell suspension-derived therapeutics
Moise, S. (CoI)
Engineering and Physical Sciences Research Council
14/10/24 → 27/04/25
Project: Research council
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Exosome-based diagnostic module for early cancer detection
Leese, H. (PI) & Moise, S. (PI)
1/01/21 → 30/08/22
Project: UK charity
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Characterizing a novel adult erythroid cell line for red blood cell manufacture
Phillips, D., Ellis, M. J., Frayne, J. & Moise, S., 6 May 2025, (E-pub ahead of print) In: Bioengineering and Translational Medicine. e70026.Research output: Contribution to journal › Article › peer-review
Open Access -
Repurposing Laboratory Plastic into Functional Fibrous Scaffolds via Green Electrospinning for Cell Culture and Tissue Engineering Applications
Berri, N., Moise, S., Keirouz, A., Jennings, A., Castro-Dominguez, B. & Leese, H. S., 10 Apr 2025, (E-pub ahead of print) In: ACS Biomaterials Science and Engineering. 13 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Advances in screening and diagnostic lab-on-chip tools for gynaecological cancers – a review
Nujhat, S., Leese, H., Di Lorenzo, M., Bowen, R. & Moise, S., 31 Dec 2023, In: Artificial Cells, Nanomedicine, and Biotechnology . 51, 1, p. 618-629 12 p.Research output: Contribution to journal › Review article › peer-review
Open Access1 Citation (SciVal) -
An impedimetric immunosensor for the selective detection of CD34+ T-cells in human serum
Diaz-Fernandez, A., Bernalte Morgado, E., Fernandez-Ramos, C., Moise, S., Estrela, P. & Di Lorenzo, M., 1 Apr 2022, In: Sensors and Actuators B: Chemical. 356, 7 p., 131306.Research output: Contribution to journal › Article › peer-review
Open AccessFile9 Citations (SciVal)140 Downloads (Pure) -
Assessing the immunosuppressive activity of alginate-encapsulated mesenchymal stromal cells on splenocytes
Moise, S., Dolcetti, L., Dazzi, F., Roach, P., Buttery, L., MacNeil, S. & Medcalf, N., 31 Dec 2022, In: Artificial Cells, Nanomedicine, and Biotechnology . 50, 1, p. 168-176 9 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Citations (SciVal)
Datasets
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Dataset for "Assessing the immunosuppressive activity of alginate-encapsulated mesenchymal stromal cells on splenocytes"
Moise, S. (Creator), University of Bath, 21 Jun 2022
DOI: 10.15125/BATH-01069
Dataset
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Dataset for "Characterising a novel adult erythroid cell line for red blood cell manufacture"
Phillips, D. (Creator), Moise, S. (Supervisor), Ellis, M. (Supervisor) & Frayne, J. (Contributor), University of Bath, 6 May 2025
DOI: 10.15125/BATH-01456
Dataset