• MILNER CENTRE 1.26

20022022

Research output per year

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Personal profile

Research interests

I am Professor and director of Bioinformatics (Milner Centre for Evolution) at the University of Bath and Co-PI of MRC CLIMB (Cloud Infrastructure for Microbial Bioinformatics)–the UKs largest cloud-based system for the analysis of microbial genomes.

Research in my group centres on the use of genetics/genomics and phenotypic studies to address complex questions in the ecology, epidemiology and evolution of microbes.

Our most recent interests focus upon comparative genome analyses to describe the core and flexible genome of pathogenic bacteria (Campylobacter, Staphylococcus, Helicobacter and Escherichia coli) and how this is related to population genetic structuring, the maintenance of species, and the evolution of host/niche adaptation and virulence.

Group website

CLIMB website

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Projects

AMR China

Sheppard, S.

MRC

1/02/1931/01/22

Project: Research council

Medical Microbial Bioinformatics

Sheppard, S. & Pascoe, B.

MRC

1/07/1631/08/20

Project: Research council

Research Output

Agricultural intensification and the evolution of host specialism in the enteric pathogen Campylobacter jejuni

Mourkas, E., Taylor, A. J., Méric, G., Bayliss, S. C., Pascoe, B., Mageiros, L., Calland, J. K., Hitchings, M. D., Ridley, A., Vidal, A., Forbes, K. J., Strachan, N. J. C., Parker, C. T., Parkhill, J., Jolley, K. A., Cody, A. J., Maiden, M. C. J., Kelly, D. J. & Sheppard, S. K., 4 May 2020, In : Proceedings of the National Academy of Sciences.

Research output: Contribution to journalArticle

Open Access

High-resolution sweep metagenomics using fast probabilistic inference

Mäklin, T., Kallonen, T., David, S., Boinett, C. J., Pascoe, B., Méric, G., Aanensen, D. M., Feil, E. J., Baker, S., Parkhill, J., Sheppard, S. K., Corander, J. & Honkela, A., 30 Jan 2020, In : Wellcome Open Research. 5, p. 14

Research output: Contribution to journalArticle

Open Access

The emergence of plasmid-borne cfr-mediated linezolid resistant-staphylococci in Vietnam

Nguyen, L. T. T., Nguyen, K. N. T., Le, P. N. T. A., Cafini, F., Pascoe, B., Sheppard, S. K., Nguyen, T. B., Hoang, T. P. N., Nguyen, T. V., Pham, T. T. K., Morikawa, K., Nguyen, D. Q. & Duong, H. X., 27 Apr 2020, In : Journal of Global Antimicrobial Resistance.

Research output: Contribution to journalArticle

Open Access

Core genome sequence analysis to characterize Salmonella enterica serovar Rissen ST469 from a swine production chain

Prasertsee, T., Chuammitri, P., Deeudom, M., Chokesajjawatee, N., Santiyanont, P., Tadee, P., Nuangmek, A., Tadee, P., Sheppard, S. K., Pascoe, B. & Patchanee, P., 2 Sep 2019, In : International Journal of Food Microbiology. 304, p. 68-74 7 p.

Research output: Contribution to journalArticle

Open Access
File

Domestication of Campylobacter jejuni NCTC 11168

Pascoe, B., Williams, L. K., Calland, J. K., Meric, G., Hitchings, M. D., Dyer, M., Ryder, J., Shaw, S., Lopes, B. S., Chintoan-Uta, C., Allan, E., Vidal, A., Fearnley, C., Everest, P., Pachebat, J. A., Cogan, T. A., Stevens, M. P., Humphrey, T. J., Wilkinson, T. S., Cody, A. J. & 12 others, Colles, F. M., Jolley, K. A., Maiden, M. C. J., Strachan, N., Pearson, B. M., Linton, D., Wren, B. W., Parkhill, J., Kelly, D. J., van Vliet, A. H. M., Forbes, K. J. & Sheppard, S. K., 1 Jul 2019, In : Microbial Genomics. 5, 7, 000279.

Research output: Contribution to journalArticle

Open Access
3 Citations (Scopus)