Projects per year
Willing to supervise doctoral students
Inhibiting tau, amyloid-β and α-synuclein toxicity: protecting neuronal network function in Dementias
Understanding microglial migration to pathogenic synapses
Assessing the neuroprotective potential and risk reducing capability of dietary polyphenolics in Alzheimer's Disease
My laboratory is interested in the molecular mechanisms underlying synaptic dysfunction and neuronal loss in Alzheimer's Disease and other forms of neurodegeneration. We are focused on cell signalling abnormalities that underpin the early stages of disease with the aim of identifying new targets for therapeutic intervention.
Member of Alzheimer's Research UK Grant Review Board: 2013 - 2019
Editorial Board of Neurochemistry International: 2015 -
Editorial Board of Nutrition and Aging: 2012 -
Editorial Advisory Board of Journal of Alzheimer's Disease: 2018 - 2019
Doctor of Science, University of Leeds
Award Date: 1 Jan 1990
Bachelor of Science, University of Leeds
Award Date: 1 Jan 1986
2/09/19 → 1/03/22
Project: UK charity
GW4 Biomed MRC DTP: Polyphenols as inhibitors of tau toxicity: protecting neuronal network function in AD
1/10/18 → 1/04/22
Project: Research council
Meade, R., Williams, R. J. & Mason, J., 19 Aug 2020, In : Nature Partner Journal - Parkinson's disease. 6, 1, 17.
Research output: Contribution to journal › ArticleOpen AccessFile13 Downloads (Pure)
Flavonoids as an Intervention for Alzheimer’s Disease: Progress and Hurdles Towards Deﬁning a Mechanism of Action: Reducing the Risk of Dementia with FlavonoidsHole, K. & Williams, R. J., 23 Jun 2020, In : Brain Plasticity. 25 p., 200098.
Research output: Contribution to journal › Review articleOpen AccessFile12 Downloads (Pure)
The Bidirectional Relationship Between Sleep and Inflammation Links Traumatic Brain Injury and Alzheimer's DiseaseGreen, T., Ortiz, J. B., Wonnacott, S., Williams, R. J. & Rowe, R. K., 25 Aug 2020, In : Frontiers in Neuroscience. 14, 894.
Research output: Contribution to journal › Review articleOpen AccessFile6 Downloads (Pure)
Meade, R., Morris, K., Watt, K., Williams, R. J. & Mason, J., 11 Nov 2020, In : Journal of Molecular Biology.
Research output: Contribution to journal › ArticleOpen AccessFile
Excitation-energy-dependent molecular beacon detects early stage neurotoxic Aβ aggregates in the presence of cortical neuronsGulácsy, C. E., Meade, R., Catici, D. A. M., Soeller, C., Pantos, G. D., Jones, D. D., Alibhai, D., Jepson, M., Valev, V. K., Mason, J. M., Williams, R. J. & Pudney, C. R., 20 Mar 2019, In : ACS Chemical Neuroscience. 10, 3, p. 1240-1250 11 p.
Research output: Contribution to journal › ArticleOpen AccessFile3 Citations (Scopus)54 Downloads (Pure)