Projects per year
Personal profile
Willing to supervise doctoral students
Gene regulatory networks in neural crest development
Modeling human disease, especially neurocristopathies, in fish models (Zebrafish and medaka)
Pigmentation genetics in zebrafish
Neural crest stem cell in vivo biology
Research interests
Neural crest (stem) cell development, especially fate specification. Dissecting the roles for transcription factors and their associated gene regulatory networks in selecting and balancing fate decisions
Pigment pattern formation, especially in adult fish.
Mathematical modelling of developmental processes; particular interest in using mathematical modelling to provide insights into stem cell biology and pigment pattern formation
Teaching interests
Cell Biology
Developmental biology, especially of nervous system, including neural crest-derived peripheral nervous system
Other responsibilities
Member of Senate (2020-)
Director of Research (Biology & Biochemistry)(2019-)
Academic Assembly Accountability and Transparency Working Group (2019-)
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Zoology, Master of Arts, -, University of Cambridge
Award Date: 1 Nov 1991
Developmental Biology, Doctor of Philosophy, Some aspects of bithorax complex expression in Schistocerca gregaria embryogenesis., University of Cambridge
1 Sept 1987 → 15 Apr 1991
Award Date: 1 Nov 1991
Natural Sciences (Part II Zoology), Bachelor of Arts, -, University of Cambridge
1 Oct 1983 → 15 Jun 1986
Award Date: 1 Jul 1986
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Collaborations and top research areas from the last five years
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A Combined and Automated High Throughput Parallel Peptide Synthesis Platform
Mason, J. (PI), Kelsh, R. (CoI), Lovell, S. (CoI), Mehrban, N. (CoI), Mrsny, R. (CoI), Perry, T. (CoI), Van Den Elsen, J. (CoI), Dela Isla, J. (Researcher), Rodrigues, D. (Researcher) & Vennard, C. (Researcher)
31/10/22 → 30/10/25
Project: Research council
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Multi User High-Content Confocal Microscope
Sero, J. (PI), Cevik, V. (CoI), Gurevich, D. (CoI), Jungwirth, U. (CoI), Kelsh, R. (CoI), Koumanov, F. (CoI), Kyprianou, A. (CoI), Laabei, M. (CoI), Licchesi, J. (CoI), Murrell, A. (CoI), Pascu, S. (CoI), Turner, L. (CoI), Walko, G. (CoI), Ward, A. (CoI), Ward, S. (CoI), Williams, R. (CoI) & Zachariadis, M. (CoI)
Biotechnology and Biological Sciences Research Council
1/08/22 → 31/07/23
Project: Research council
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Rethinking the neural crest – a novel dynamic model of neural crest fate restriction
Kelsh, R. (PI) & Kelsh, R. (PI)
Biotechnology and Biological Sciences Research Council
1/09/19 → 15/12/23
Project: Research council
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Bringing Light Sheet Fluorescence Microscopy to the University of Bath
Kelsh, R. (PI), De Bank, P. (CoI), Ellis, M. (CoI), Gebhard, S. (CoI), Gill, R. (CoI), Jones, B. (CoI), Mrsny, R. (CoI) & Vance, K. (CoI)
Biotechnology and Biological Sciences Research Council
1/07/19 → 30/06/20
Project: Research council
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Bioinformatics of Gene Regulatory Networks during Neural Crest Development
Kelsh, R. (PI)
28/02/18 → 27/02/23
Project: Research council
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Environmental education in the classroom: pilot study in Cabo Verde suggests differing impacts on local knowledge and environmental attitudes.
Rice, R., Hejmadi, M., Silva, H., Kelsh, R. N., Agues, J., Engel, N. & Székely, T., 31 Mar 2024, In: Oryx. 58, 2, p. 210-217Research output: Contribution to journal › Article › peer-review
Open AccessFile126 Downloads (Pure) -
Oscillatory differentiation dynamics fundamentally restricts the resolution of pseudotime reconstruction algorithms
Huy, V., Dawes, J. H. P. & Kelsh, R. N., 31 Mar 2024, In: Journal of the Royal Society, Interface. 21, 212, 18 p., 20230537.Research output: Contribution to journal › Article › peer-review
Open Access -
UV luminescence in Jersey Tiger moths
Zachariadis, M., Valev, E., Valev, K., Lednitzky, D., Choi, H., Fletcher, P., Kelsh, R. N. & Valev, V. K., 10 Jun 2024, Nanophotonics X. Andrews, D. L., Bain, A. J. & Ambrosio, A. (eds.). U. S. A.: SPIE, 129911R. (Proceedings of SPIE - The International Society for Optical Engineering; vol. 12991).Research output: Chapter or section in a book/report/conference proceeding › Chapter in a published conference proceeding
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A gene regulatory network combining Pax3/7, Sox10 and Mitf generates diverse pigment cell types in medaka and zebrafish
Miyadai, M., Takada, H., Shiraishi, A., Kimura, T., Watakabe, I., Kobayashi, H., Nagao, Y., Naruse, K., Higashijima, S. I., Shimizu, T., Kelsh, R. N., Hibi, M. & Hashimoto, H., 31 Oct 2023, In: Development (Cambridge). 150, 19, dev202114.Research output: Contribution to journal › Article › peer-review
Open Access11 Citations (SciVal) -
Myron Gordon Award Lecture 2023: Painting the neural crest: How studying pigment cells illuminates neural crest cell biology
Kelsh, R. N., 27 Nov 2023, In: Pigment Cell & Melanoma Research. 7 p.Research output: Contribution to journal › Review article › peer-review
Open Access
Datasets
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Dataset for "A systems biology approach uncovers the core gene regulatory network governing iridophore fate choice from the neural crest"
Kelsh, R. (Creator), Petratou, K. (Creator) & Subkhankulova, T. (Creator), University of Bath, 17 Aug 2018
DOI: 10.15125/BATH-00502
Dataset
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Dataset for "Endothelin receptor Aa regulates proliferation and differentiation of Erb-dependant pigment progenitors in zebrafish"
Kelsh, R. (Creator), Camargo Sosa, K. (Creator), Colanesi, S. (Creator) & Müller, J. (Creator), University of Bath, 23 Jan 2019
DOI: 10.15125/BATH-00503
Dataset
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Dataset for Petratou, Spencer, Kelsh and Lister 'The MITF paralog tfec is required in neural crest development for fate specification of the iridophore lineage from a multipotent pigment cell progenitor'
Petratou, K. (Creator), Lister, J. A. (Creator) & Kelsh, R. (Creator), University of Bath, 5 Jan 2021
DOI: 10.15125/BATH-00743
Dataset
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An ongoing role for Wnt signaling in differentiating melanocytes in vivo
Kelsh, R. (Creator), University of Bath, 2016
DOI: 10.15125/BATH-00324
Dataset
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Dataset for Sox10 contributes to the balance of fate choice in dorsal root ganglion progenitors
Kelsh, R. (Creator), University of Bath, 2016
DOI: 10.15125/BATH-00164
Dataset