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Richard Guy

Prof

 https://orcid.org/0000-0003-3227-9862

  • 7 WEST 3.13

1993 …2023
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Research Output 1993 2019

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Article
2019

Mechanism of human nail poration by high-repetition-rate, femtosecond laser ablation

Vanstone, S., Stone, J., Gordeev, S. & Guy, R., 23 Apr 2019, In : Drug Delivery and Translational Research. 12 p.

Research output: Contribution to journal › Article

Open Access
1 Citation (Scopus)

Potential of iontophoresis as a drug delivery method for midazolam in pediatrics

Djabri, A., Guy, R. & Delgado-Charro, M., 1 Feb 2019, In : European Journal of Pharmaceutical Sciences. 128, p. 137-143 7 p.

Research output: Contribution to journal › Article

2018
1 Citation (Scopus)

Comparison of patient (POEM), observer (EASI, SASSAD, TIS) and corneometry measures of emollient effectiveness in children with eczema: findings from the COMET feasibility trial

Ridd, M. J., Gaunt, D. M., Guy, R. H., Redmond, N. M., Garfield, K., Hollinghurst, S., Ball, N., Shaw, L., Purdy, S. & Metcalfe, C., 1 Aug 2018, In : British Journal of Dermatology. 179, 2, p. 362-370 9 p.

Research output: Contribution to journal › Article

Open Access
File
Emollients
Eczema
Atopic Dermatitis
Outcome Assessment (Health Care)

Dermal Absorption of Pesticide Residues

Clarke, J., Cordery, S., Morgan, N. A., Knowles, P. & Guy, R., 17 Dec 2018, In : Chemical Research in Toxicology. 31, 12, p. 1356-1363

Research output: Contribution to journal › Article

File
20 Citations (Scopus)

Non-invasive, transdermal, path-selective and specific glucose monitoring via a graphene-based platform

Lipani, L., Dupont, B. G. R., Doungmene, F., Marken, F., Tyrrell, R. M., Guy, R. H. & Ilie, A., 30 Jun 2018, In : Nature Nanotechnology. 13, 6, p. 504-511 8 p.

Research output: Contribution to journal › Article

Open Access
File
Graphite
glucose
Graphene
Glucose
graphene

Topical bio(in)equivalence of metronidazole formulations in vivo

Pedon de Araujo, T., Moura Fittipaldi, I., Galindo Bedor, D. C., Ludna Duarte, M., Cordery, S., Guy, R., Delgado-Charro, M., Pereira de Santana, D. & Bastos Leal, L., 25 Apr 2018, In : International Journal of Pharmaceutics. 541, p. 167-172 6 p.

Research output: Contribution to journal › Article

Open Access
File
Metronidazole
Cornea
Skin
Pharmaceutical Preparations
Biological Availability
2017
7 Citations (Scopus)

Bioequivalence methodologies for topical drug products: in vitro and ex vivo studies with a cortiscosteroid and an anti-fungal drug

Bastos Leal, L., Cordery, S. F., Delgado-Charro, M. B., Bunge, A. L. & Guy, R. H., Apr 2017, In : Pharmaceutical Research. 34, 4, p. 730-737 8 p.

Research output: Contribution to journal › Article

Open Access

Precise laser poration to control drug delivery into and through human nail

Vanstone, S., Cordery, S., Stone, J., Gordeev, S. & Guy, R., 28 Dec 2017, In : Journal of Controlled Release. 268, p. 72-77 6 p.

Research output: Contribution to journal › Article

Open Access
File
Drug and Narcotic Control
Nails
Lasers
Pharmaceutical Preparations
Nail Diseases
3 Citations (Scopus)

Reverse iontophoretic extraction of metabolites from living plants and their identification by ion-chromatography coupled to high resolution mass spectrometry

Gonzalez-Sanchez, M. I., McCullagh, J., Guy, R. & Compton, R., May 2017, In : Phytochemical Analysis. 28, 3, p. 195-201 7 p.

Research output: Contribution to journal › Article

Ion chromatography
ion exchange chromatography
Metabolites
Mass spectrometry
Chromatography
6 Citations (Scopus)

Topical bioavailability of diclofenac from locally-acting, dermatological formulations

Cordery, S. F., Pensado, A., Chiu, W. S., Shehab, M. Z., Bunge, A. L., Delgado-Charro, M. B. & Guy, R. H., 30 Aug 2017, In : International Journal of Pharmaceutics. 529, 1-2, p. 55-64 10 p.

Research output: Contribution to journal › Article

Open Access
File
Diclofenac
Biological Availability
Skin
Pharmaceutical Preparations
Cornea
2016
18 Citations (Scopus)

Assessing the safety of cosmetic chemicals: consideration of a flux decision tree to predict dermally delivered systemic dose for comparison with oral TTC (Threshold of Toxicological Concern)

Williams, F. M., Rothe, H., Barrett, G., Chiodini, A., Whyte, J., Cronin, M. T. D., Monteiro-Riviere, N. A., Plautz, J., Roper, C., Westerhout, J., Yang, C. & Guy, R. H., 1 Apr 2016, In : Regulatory Toxicology and Pharmacology. 76, p. 174-186 13 p.

Research output: Contribution to journal › Article

Open Access
Chemical Safety
Decision Trees
Cosmetics
Decision trees
Toxicology
10 Citations (Scopus)

Choice of moisturiser for eczema treatment (COMET): feasibility study of a randomised controlled parallel group trial in children recruited from primary care

Ridd, M., Garfield, K., Gaunt, D., Hollinghurst, S., Redmond, N., Powell, K., Wilson, V., Guy, R., Ball, N., Shaw, L., Purdy, S. & Metcalfe, C., 16 Nov 2016, In : BMJ Open. 6, 11, 9 p., e012021.

Research output: Contribution to journal › Article

Open Access
Emollients
Eczema
Feasibility Studies
Primary Health Care
Therapeutics
8 Citations (Scopus)

Femtosecond pulsed laser ablation to enhance drug delivery across the skin

Garvie-Cook, H., Stone, J. M., Yu, F., Guy, R. H. & Gordeev, S. N., Jan 2016, In : Journal of Biophotonics. 9, 1-2, p. 144-154 11 p.

Research output: Contribution to journal › Article

Laser Therapy
inks
Laser ablation
Pulsed lasers
Drug delivery
7 Citations (Scopus)

Ibuprofen delivery into and through the skin from novel oxidized cellulose-based gels and conventional topical formulations

Celebi, D., Edler, K., Scott, J. & Guy, R., 30 Nov 2016, In : International Journal of Pharmaceutics. 514, p. 238-243 6 p.

Research output: Contribution to journal › Article

Open Access
File
oxidized cellulose
Ibuprofen
Gels
Skin
Cornea
9 Citations (Scopus)

Managing diabetes through the skin: Diagnostic devices

Guy, R., Jun 2016, In : Nature Nanotechnology. 11, 6, p. 493-494 2 p.

Research output: Contribution to journal › Article

Open Access
File
Medical problems
Gold
Skin
sweat
Controlled drug delivery
4 Citations (Scopus)

Modelling drug flux through microporated skin

Rzhevskiy, A. S., Guy, R. H. & Anissimov, Y. G., 10 Nov 2016, In : Journal of Controlled Release. 241, p. 194-199 6 p.

Research output: Contribution to journal › Article

Open Access
File
Drug Design
Skin
Pharmaceutical Preparations
Theoretical Models
Molecular Weight
6 Citations (Scopus)

The potential of polymeric film-forming systems as sustained delivery platforms for topical drugs

Frederiksen, K., Guy, R. H. & Petersson, K., 2016, In : Expert Opinion on Drug Delivery. 13, 3, p. 349-360

Research output: Contribution to journal › Article

Open Access
File
Skin
Patient Compliance
Pharmaceutical Preparations
Expert Testimony
Drug Delivery Systems
2015
3 Citations (Scopus)

Biophysical elucidation of the mechanism of enhanced drug release and topical delivery from polymeric film-forming systems

Garvie-Cook, H., Frederiksen, K., Petersson, K., Guy, R. & Gordeev, S., 28 Aug 2015, In : Journal of Controlled Release. 212, p. 103-112 10 p.

Research output: Contribution to journal › Article

Open Access
File
Betamethasone Valerate
Triglycerides
Polymers
Skin
Raman Spectrum Analysis
8 Citations (Scopus)

Characterization of Topical Film-Forming Systems Using Atomic Force Microscopy and Raman Microspectroscopy

Garvie-cook, H., Frederiksen, K., Petersson, K., Guy, R. H. & Gordeev, S., Mar 2015, In : Molecular Pharmaceutics. 12, 3, p. 751-757 7 p.

Research output: Contribution to journal › Article

Open Access
File
Plasticizers
Atomic Force Microscopy
Elastic Modulus
Betamethasone Valerate
Skin
11 Citations (Scopus)

Choice of Moisturiser for Eczema Treatment (COMET): Study protocol for a randomized controlled trial

Ridd, M. J., Redmond, N. M., Hollinghurst, S., Ball, N., Shaw, L., Guy, R., Wilson, V., Metcalfe, C. & Purdy, S., 15 Jul 2015, In : Trials. 16, 304.

Research output: Contribution to journal › Article

Open Access
File
Emollients
Eczema
Clinical Protocols
Randomized Controlled Trials
Feasibility Studies
16 Citations (Scopus)

Development and in vitro evaluation of lipid nanoparticle-based dressings for topical treatment of chronic wounds

Gainza, G., Chu, W. S., Guy, R. H., Pedraz, J. L., Hernandez, R. M., Delgado-Charro, B. & Igartua, M., 25 Jul 2015, In : International Journal of Pharmaceutics. 490, 1-2, p. 404-411 8 p.

Research output: Contribution to journal › Article

File
Bandages
Nanoparticles
Lipids
Wounds and Injuries
Fibrin
16 Citations (Scopus)

Drug delivery into microneedle-porated nails from nanoparticle reservoirs

Chiu, W. S., Belsey, N. A., Garrett, N. L., Moger, J., Price, G. J., Delgado-Charro, M. B. & Guy, R. H., 28 Dec 2015, In : Journal of Controlled Release. 220, A, p. 98-106 9 p.

Research output: Contribution to journal › Article

Open Access
File
Nails
Nanoparticles
Pharmaceutical Preparations
Raman Spectrum Analysis
Optical Imaging
23 Citations (Scopus)

Formulation considerations in the design of topical, polymeric film-forming systems for sustained drug delivery to the skin

Frederiksen, K., Guy, R. H. & Petersson, K., Apr 2015, In : European Journal of Pharmaceutics and Biopharmaceutics. 91, p. 9-15 7 p.

Research output: Contribution to journal › Article

Open Access
File
Plasticizers
Drug Delivery Systems
Betamethasone Valerate
Skin
Polymers
10 Citations (Scopus)

In situ detection of salicylate in Ocimum basilicum plant leaves via reverse iontophoresis

González-Sánchez, M. I., Lee, P. T., Guy, R. H. & Compton, R. G., 28 Nov 2015, In : Chemical Communications. 51, 92, p. 16534-16536 3 p.

Research output: Contribution to journal › Article

Open Access
File
Salicylates
Cyclic voltammetry
Electrodes
Chemical analysis
Iontophoresis
2 Citations (Scopus)

In vitro method to quantify dermal absorption of pesticide residues

Clarke, J. F., Cordery, S. F., Morgan, N. A., Knowles, P. K. & Guy, R. H., 16 Feb 2015, In : Chemical Research in Toxicology. 28, 2, p. 166-168

Research output: Contribution to journal › Article

Open Access
File
16 Citations (Scopus)

Iontophoresis of minoxidil sulphate loaded microparticles, a strategy for follicular drug targeting?

Gelfuso, G. M., Barros, M. A. D. O., Delgado-Charro, M. B., Guy, R. H. & Lopez, R. F. V., Oct 2015, In : Colloids and Surfaces B: Biointerfaces. 134, p. 408-412 5 p.

Research output: Contribution to journal › Article

Open Access
File
Iontophoresis
microparticles
Drug Delivery Systems
Hair Follicle
hair
2 Citations (Scopus)

Iontophoretic transdermal sampling of iohexol as a noninvasive tool to assess glomerular filtration rate

Djabri, A., van’t Hoff, W., Brock, P., Wong, I. C. K., Guy, R. & Delgado-Charro, B., 1 Feb 2015, In : Pharmaceutical Research. 32, 2, p. 590-603

Research output: Contribution to journal › Article

Open Access
File
Iohexol
Iontophoresis
Glomerular Filtration Rate
Sampling
Pediatrics
23 Citations (Scopus)

Molecular diffusion in the human nail measured by stimulated Raman scattering microscopy

Chiu, W-S., Belsey, N., Garrett, N. L., Moger, J., Delgado-Charro, M. & Guy, R., 15 May 2015, In : Proceedings of the National Academy of Sciences of the United States of America. 112, 25, p. 7725-7730

Research output: Contribution to journal › Article

Open Access
File
Raman Spectrum Analysis
Nails
Microscopy
Nail Diseases
Propylene Glycol
5 Citations (Scopus)

Topical formulation and dermal delivery of active phenolic compounds in the Thai medicinal plant - Clerodendrum petasites S. Moore

Thitilertdecha, P., Rowan, M. G. & Guy, R. H., 15 Jan 2015, In : International Journal of Pharmaceutics. 478, 1, p. 39-45 7 p.

Research output: Contribution to journal › Article

Open Access
File
Petasites
Clerodendrum
Vanillic Acid
Medicinal Plants
Cornea
2014
23 Citations (Scopus)

A non-rewarding, non-aversive buprenorphine/naltrexone combination attenuates drug-primed reinstatement to cocaine and morphine in rats in a conditioned place preference paradigm

Cordery, S. F., Taverner, A., Ridzwan, I. E., Guy, R. H., Delgado-Charro, M. B., Husbands, S. M. & Bailey, C. P., 1 Jul 2014, In : Addiction Biology. 19, 4, p. 575-586 12 p.

Research output: Contribution to journal › Article

Open Access
File
Buprenorphine
Naltrexone
Drug Combinations
Cocaine
Morphine
24 Citations (Scopus)

Characterisation of polyphenolic compounds in Clerodendrum petasites S. Moore and their potential for topical delivery through the skin

Thitilertdecha, P., Guy, R. H. & Rowan, M. G., 11 Jun 2014, In : Journal of Ethnopharmacology. 154, 2, p. 400-407 8 p.

Research output: Contribution to journal › Article

Open Access
File
Petasites
Clerodendrum
Vanillic Acid
Apigenin
Skin
6 Citations (Scopus)

Characterisation of skin barrier function using bioengineering and biophysical techniques

Yang, Q. & Guy, R. H., 5 Aug 2014, In : Pharmaceutical Research. 32, 2, p. 445-457

Research output: Contribution to journal › Article

Open Access
File
Bioengineering
Forehead
Cornea
Skin
Forearm
36 Citations (Scopus)

Evaluation of drug delivery to intact and porated skin by coherent Raman scattering and fluorescence microscopies

Belsey, N. A., Garrett, N. L., Contreras-Rojas, L. R., Pickup-Gerlaugh, A. J., Price, G. J., Moger, J. & Guy, R. H., 28 Jan 2014, In : Journal of Controlled Release. 174, 28, p. 37-42

Research output: Contribution to journal › Article

Open Access
File
Drug Evaluation
Raman Spectrum Analysis
Fluorescence Microscopy
Skin
Microscopy
4 Citations (Scopus)

Serious photocontact dermatitis induced by topical ketoprofen depends on the formulation

Guy, R. H., Kuma, H. & Nakanishi, M., May 2014, In : European Journal of Dermatology. 24, 3, p. 365-371 7 p.

Research output: Contribution to journal › Article

Open Access
File
Photoallergic Dermatitis
Ketoprofen
Photosensitivity Disorders
Phototoxic Dermatitis
Photolysis
79 Citations (Scopus)

Transdermal drug delivery: 30 + years of war and still fighting!

Wiedersberg, S. & Guy, R. H., 28 Sep 2014, In : Journal of Controlled Release. 190, p. 150-156

Research output: Contribution to journal › Article

Open Access
File
Pharmaceutical Preparations
Cutaneous Administration
Skin
Technology
Research
2013
8 Citations (Scopus)

Effects of iontophoresis, hydration, and permeation enhancers on human nail plate: Infrared and impedance spectroscopy assessment

Benzeval, I., Bowen, C. R., Guy, R. H. & Delgado-Charro, M. B., Jun 2013, In : Pharmaceutical Research. 30, 6, p. 1652-1662 11 p.

Research output: Contribution to journal › Article

Open Access
File
Dielectric Spectroscopy
Iontophoresis
Nails
Permeation
Hydration
19 Citations (Scopus)

Iontophoresis-targeted, follicular delivery of minoxidil sulfate for the treatment of alopecia

Gelfuso, G. M., Gratieri, T., Delgado-Charro, M. B., Guy, R. H. & Vianna Lopez, R. F., 1 May 2013, In : Journal of Pharmaceutical Sciences. 102, 5, p. 1488-1494

Research output: Contribution to journal › Article

Iontophoresis
Alopecia
Minoxidil
Sulfates
Hair Follicle
12 Citations (Scopus)

Mechanical tomography of human corneocytes with a nanoneedle

Beard, J. D., Guy, R. H. & Gordeev, S. N., Jun 2013, In : Journal Of Investigative Dermatology. 133, 6, p. 1565-1571 7 p.

Research output: Contribution to journal › Article

Open Access
File
Nanoneedles
Atomic Force Microscopy
Tomography
Atomic force microscopy
Mechanical properties

Products in "Bounty bags" potentially harm newborn skin

Ridd, M., Guy, R., Ball, N., Roberts, A. & Williams, H., 22 Jun 2013, In : BMJ . 346, 7913, f3895.

Research output: Contribution to journal › Article

5 Citations (Scopus)

Transdermal flux predictions for selected selective oestrogen receptor modulators (SERMs): Comparison with experimental results

Güngör, S., Delgado-Charro, M. B., Masini-Etévé, V., Potts, R. O. & Guy, R. H., 28 Dec 2013, In : Journal of Controlled Release. 172, 3, p. 601-606 6 p.

Research output: Contribution to journal › Article

Open Access
File
Selective Estrogen Receptor Modulators
Skin
Danazol
Water
Epidermis
2012
28 Citations (Scopus)

Comparison of gravimetric and spectroscopic approaches to quantify stratum corneum removed by tape-stripping

Mohammed, D., Yang, Q., Guy, R. H., Matts, P. J., Hadgraft, J. & Lane, M. E., Sep 2012, In : European Journal of Pharmaceutics and Biopharmaceutics. 82, 1, p. 171-174

Research output: Contribution to journal › Article

Cornea
Densitometry
Surgical Tape
Volunteers
Proteins
8 Citations (Scopus)

Novel imaging method to quantify stratum corneum in dermatopharmacokinetic studies

Russell, L. M. & Guy, R. H., Sep 2012, In : Pharmaceutical Research. 29, 9, p. 2389-2397 9 p.

Research output: Contribution to journal › Article

Open Access
File
Cornea
Tapes
Imaging techniques
Weighing
Therapeutic Equivalency
6 Citations (Scopus)

Novel imaging method to quantify stratum corneum in dermatopharmacokinetic studies: Proof-of-concept with acyclovir formulations

Russell, L. M. & Guy, R. H., Dec 2012, In : Pharmaceutical Research. 29, 12, p. 3362-3372 11 p.

Research output: Contribution to journal › Article

Open Access
File
Acyclovir
Cornea
Tapes
Imaging techniques
Weighing
73 Citations (Scopus)

Objective assessment of nanoparticle disposition in mammalian skin after topical exposure

Campbell, C. S. J., Contreras-Rojas, L. R., Delgado-Charro, B. & Guy, R. H., 20 Aug 2012, In : Journal of Controlled Release. 162, 1, p. 201-207 7 p.

Research output: Contribution to journal › Article

Open Access
File
Nanoparticles
Skin
Sebum
Polystyrenes
Drug Delivery Systems
17 Citations (Scopus)

Passive and iontophoretic transdermal delivery of phenobarbital: implications in paediatric therapy

Djabri, A., Guy, R. H. & Delgado-Charro, M. B., 2012, In : International Journal of Pharmaceutics. 435, 1, p. 76-82

Research output: Contribution to journal › Article

Open Access
File
Phenobarbital
Pediatrics
Skin
Iontophoresis
Drug Compounding
32 Citations (Scopus)

Transdermal iontophoresis of ranitidine: An opportunity in paediatric drug therapy

Djabri, A., Guy, R. H. & Delgado-Charro, M. B., 1 Oct 2012, In : International Journal of Pharmaceutics. 435, 1, p. 27-32

Research output: Contribution to journal › Article

Open Access
File
Iontophoresis
Ranitidine
Pediatrics
Drug Therapy
Gels
2011
1 Citation (Scopus)

AFM nanotools for surgery of biological Cells

Beard, J. D., Gordeev, S. N. & Guy, R. H., 2011, In : Journal of Physics: Conference Series. 286, 1, 012003.

Research output: Contribution to journal › Article

surgery
atomic force microscopy
manipulators
surface layers
electron beams
10 Citations (Scopus)

Assessment of dermal exposure to pesticide residues during re-entry

Belsey, N. A., Cordery, S. F., Bunge, A. L. & Guy, R. H., 15 May 2011, In : Environmental Science & Technology. 45, 10, p. 4609-4615 7 p.

Research output: Contribution to journal › Article

Open Access
File
Pesticide Residues
pesticide residue
Reentry
Pesticides
pesticide
89 Citations (Scopus)

Imaging drug delivery to skin with stimulated Raman scattering microscopy

Saar, B. G., Contreras-Rojas, L. R., Xie, X. S. & Guy, R. H., 6 Jun 2011, In : Molecular Pharmaceutics. 8, 3, p. 969-975 7 p.

Research output: Contribution to journal › Article

Open Access
File
Raman Spectrum Analysis
Microscopy
Skin
Pharmaceutical Preparations
Three-Dimensional Imaging
148 Citations (Scopus)

Mathematical models of skin permeability: An overview

Mitragotri, S., Anissimov, Y. G., Bunge, A. L., Frasch, H. F., Guy, R. H., Hadgraft, J., Kasting, G. B., Lane, M. E. & Roberts, M. S., 10 Oct 2011, In : International Journal of Pharmaceutics. 418, 1, p. 115-129 15 p.

Research output: Contribution to journal › Article

Open Access
File
Permeability
Theoretical Models
Skin
Research
Pharmaceutical Preparations
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