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Ravi Acharya

Prof

  • 4 SOUTH 0.29

20012020

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Peptidyl-Dipeptidase A Medicine & Life Sciences
Clostridium difficile Medicine & Life Sciences
Catalytic Domain Medicine & Life Sciences
Neurotoxins Medicine & Life Sciences
Proteins Medicine & Life Sciences
Angiotensin-Converting Enzyme Inhibitors Medicine & Life Sciences
Pancreatic Ribonuclease Medicine & Life Sciences
Glycosyltransferases Medicine & Life Sciences

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Projects 2002 2020

Structure-function Studies on Human Angiotensin-l Concervting Enzyme (Human ACE)

Acharya, K.

MRC

1/02/16 → 31/01/20

Project: Research council

Expression and Purification of C21 orf2 Protein (Implicated in ALS) for Structural and Functional Studies

Acharya, K.

Motor Neurone Disease Association

1/06/18 → 31/05/19

Project: UK charity

Structure-Function Studies on Clostridium Difficile Large Toxins

Acharya, K.

MRC

1/04/14 → 31/03/17

Project: Research council

Complementary Approaches in Structural Molecular Biology

Acharya, K.

The Royal Society

1/01/14 → 31/01/14

Project: Research council

Structure-function studies on ALS associated C9orf72 Protein

Acharya, K. & Subramanian, V.

Motor Neurone Disease Association

1/12/13 → 30/11/16

Project: UK charity

Research Output 2001 2018

A comparative bioinformatic analysis of C9orf72

Iyer, S., Acharya, K. R. & Subramanian, V. 19 Feb 2018 In : PeerJ. 6, p. e4391

Research output: Contribution to journal › Article

Open Access
Saimiriine herpesvirus 2
Supravalvular Aortic Stenosis
Cyclic AMP Receptor Protein
Frontotemporal Dementia
Submandibular Gland

Crystal structures of sampatrilat and sampatrilat-Asp in complex with human ACE: a molecular basis for domain-selectivity

Cozier, G. E., Schwager, S. L., Sharma, R. K., Chibale, K., Sturrock, E. D. & Acharya, K. R. 24 Feb 2018 In : FEBS Journal.

Research output: Contribution to journal › Article

Open Access
Peptidyl-Dipeptidase A
Hydrophobic and Hydrophilic Interactions
Angiotensin-Converting Enzyme Inhibitors
Lysine
Catalytic Domain

High resolution crystal structures of the receptor-binding domain of neurotoxin serotypes A and FA

Davies, J. R., Hackett, G. S., Liu, S. M. & Acharya, K. R. 21 Mar 2018 In : PeerJ. 6, e4552

Research output: Contribution to journal › Article

Open Access
Neurotoxins
Cytochrome c Group
receptors
botulinum toxin
Disulfides
1 Citations

Investigation into the Mechanism of Homo- and Heterodimerization of Angiotensin-Converting Enzyme

Abrie, J. A., Moolman, W. J. A., Cozier, G. E., Schwager, S. L. U., Acharya, K. R. & Sturrock, E. D. 1 Apr 2018 In : Molecular Pharmacology. 93, 4, p. 344-354

Research output: Contribution to journal › Article

Open Access
Hominidae
Peptidyl-Dipeptidase A
Dimerization
Renin-Angiotensin System
Testis

Prediction of structural consequences for disease causing variants in C21orf2 protein using computational approaches

Iyer, S., Acharya, K. R. & Subramanian, V. 17 Jan 2018 In : Journal of Biomolecular Structure & Dynamics. p. 1-32 32 p.

Research output: Contribution to journal › Article

Amyotrophic Lateral Sclerosis
Mutation
Proteins
Motor Neuron Disease
Missense Mutation