If you made any changes in Pure these will be visible here soon.

Research Output 2000 2018

2005
54 Citations (Scopus)

Multiple protein interactions involving proposed extracellular loop domains of the tight junction protein occludin

Nusrat, A., Brown, G. T., Tom, J., Drake, A., Bui, T. T., Quan, C. & Mrsny, R. J., 2005, In : Molecular Biology of the Cell. 16, 4, p. 1725-1734 10 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)
50 Citations (Scopus)

The second loop of occludin is required for suppression of Raf-1induced tumor growth

Wang, Z., Mrsny, R. J. & et al, N. V., 2005, In : Oncogene. 24, 27, p. 4412-4420 9 p.

Research output: Contribution to journalArticle

Tight junctions; more than a permeability barrier

Nusrat, A. & Mrsny, R. J., 2005, In : Advanced Drug Delivery Reviews. 57

Research output: Contribution to journalArticle

2004
1 Citation (Scopus)

A perspective on current and future synthetic reflexive systems

Park, K., Yui, N. & Mrsny, R. J., 2004, Multi-Reflexive Polymers and Hydrogels: Understanding and Designing Fast-Responsive Polymeric Systems. Yui, N., Mrsny, R. & Park, K. (eds.). Boca Raton, Florida: CRC Press, p. 427-437 11 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

122 Citations (Scopus)

Identification of hepoxilin A 3 in inflammatory events: a required role in neutrophil migration across intestinal epithelia

Mrsny, R. J., Gewirtz, A. T., Siccardi, D., Savidge, T., Hurley, B. P., Madara, J. L. & McCormick, B. A., 2004, In : Proceedings of the National Academy of Sciences of the United States of America. 101, 19, p. 7421-7426 6 p.

Research output: Contribution to journalArticle

Learning from nature: examples of rapid, repetitive, responsive biological events

Mrsny, R. J., 2004, Multi-Reflexive Polymers and Hydrogels: Understanding and Designing Fast-Responsive Polymeric Systems. Yui, N., Mrsny, R. J. & Park, K. (eds.). Boca Raton, Florida: CRC Press, p. 3-15 13 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Modulation of tight junctional permeability (Preface)

Thanou, M. & Mrsny, R. J., 2004, In : Journal of Drug Targeting. 12, 2, p. 63-63 1 p.

Research output: Contribution to journalArticle

Multi-Reflexive Polymers and Hydrogels: Understanding and Designing Fast-Responsive Polymeric Systems

Yui, N. (ed.), Mrsny, R. (ed.) & Park, K. (ed.), 2004, Boca Raton, Florida: CRC Press.

Research output: Book/ReportBook

49 Citations (Scopus)

Polymorphonuclear cell transmigration induced by Pseudomonas aeruginosa requires the eicosanoid hepoxilin A 3 1

Hurley, B. P., Siccardi, D., Mrsny, R. J. & McCormick, B. A., 2004, In : The Journal of Immunology. 173, 9, p. 5712-5720 9 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Strategies for targeting protein therapeutics to selected tissues and cells

Mrsny, R. J., 2004, In : Expert Opinion on Biological Therapy. 4, 1, p. 65-73 9 p.

Research output: Contribution to journalArticle

Tight junctions - more than a permeability barrier

Thanou, M. & Mrsny, R. J., 2004, In : Journal of Drug Targeting. 12, 2, p. 63 1 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Tissue and cell specific targeting

Mrsny, R. J., 2004, Gene Delivery: Principles and Applications. Amiji, M. M. (ed.). Boca Raton, Florida: CRC Press, p. 5-27 23 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2003
13 Citations (Scopus)

Emerging technologies that overcome biological barriers for therapeutic protein delivery

Daugherty, A. L. & Mrsny, R. J., 2003, In : Expert Opinion on Biological Therapy. 3, 7, p. 1071-1081 11 p.

Research output: Contribution to journalArticle

2002
264 Citations (Scopus)

A membrane-permeant peptide that inhibits MLC kinase restores barrier function in In Vitro models of intestinal disease

Zolotarevsky, Y., Hecht, G., Koutsouris, A., Gonzalez, D. E., Quan, C., Tom, J., Mrsny, R. J. & Turner, J. R., 2002, In : Gastroenterology. 123, 1, p. 163-172 10 p.

Research output: Contribution to journalArticle

40 Citations (Scopus)

Analysis methods of polysorbate 20: a new method to assess the stability of polysorbate 20 and established methods that may overlook degraded polysorbate 20

Khossravi, M., Kao, Y. H., Mrsny, R. J. & Sweeney, T. D., 2002, In : Pharmaceutical Research. 19, 5, p. 634-639 6 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Bacterial toxins as tools for mucosal vaccination

Mrsny, R. J., Daugherty, A. L., McKee, M. L. & Fitzgerald, D. J., 2002, In : Drug Discovery Today. 7, 4, p. 247-258 12 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)

Cdc42 and Rac1 regulate late events in Salmonella typhimurium -induced Interleukin-8 secretion from polarizedepithelial cells

Hobert, M. E., Sands, K. A., Mrsny, R. J. & Madara, J. L., 2002, In : Journal of Biological Chemistry. 277, 52, p. 51025-51032 8 p.

Research output: Contribution to journalArticle

2001
32 Citations (Scopus)

Dual-function vaccine for Pseudomonas aeruginosa : characterization of chimeric exotoxin A-Pilin protein

Hertle, R., Mrsny, R. & Fitzgerald, D. J., 2001, In : Infection and immunity. 69, 11, p. 6962-6969 8 p.

Research output: Contribution to journalArticle

153 Citations (Scopus)

Emerging protein delivery methods

Cleland, J. L., Daugherty, A. & Mrsny, R., 2001, In : Current Opinion in Biotechnology. 12, p. 212-219 8 p.

Research output: Contribution to journalArticle

2000
82 Citations (Scopus)

Characterization of huJAM: evidence for involvement in cell-cell contact and tight junction regulation

Liang, T. W., Demarco, R. A., Mrsny, R. J., Gurney, A., Gray, A., Hooley, J., Aaron, H. L., Huang, A., Klassen, T., Tumas, D. B. & Fong, S., 2000, In : American Journal of Physiology - Cell Physiology. 279, 6, p. C1733-C1743

Research output: Contribution to journalArticle

Junctional Adhesion Molecules
Intercellular Junctions
Tight Junctions
Cell Communication
Epithelium

Choice of microcentrifuge tubes influences T cell proliferation assay

Wei, Y., Mrsny, R., Blumberg, R. S., Fried, M. & Christ, A. D., Jul 2000, In : Biotechniques. 29, 1, p. 54-59 6 p.

Research output: Contribution to journalArticle

Controlled Drug Delivery: Designing Technologies for the Future

Park, K. (ed.) & Mrsny, R. J. (ed.), 2000, Washington, DC: American Chemical Society.

Research output: Book/ReportBook

Technology
Drug Administration Routes
Pharmaceutical Preparations
Equipment and Supplies
Magic
8 Citations (Scopus)

Epithelial application of Pseudomonas aeruginosa exotoxin A results in a selective targeting to cells in the liver, spleen and lymph node

Daugherty, A. L., McKee, M. L., FitzGerald, D. J. & Mrsny, R. J., 2000, In : Journal of Controlled Release. 65, 1-2, p. 297-302 6 p.

Research output: Contribution to journalArticle

Spleen
Lymph Nodes
Liver
Immunization
Viral Antigens
51 Citations (Scopus)

Modulation of tight junction function by G protein-coupled events

Hopkins, A. M., Li, D. X., Mrsny, R. J., Walsh, S. V. & Nusrat, A., 2000, In : Advanced Drug Delivery Reviews. 41, 3, p. 329-340 12 p.

Research output: Contribution to journalArticle

Monomeric GTP-Binding Proteins
Tight Junctions
GTP-Binding Proteins
Guanine Nucleotides
GTP Phosphohydrolases
13 Citations (Scopus)

New approaches to antigen delivery

FitzGerald, D. & Mrsny, R. J., 2000, In : Critical Review of Therapeutic Drug Carrier Systems. 17, 3, p. 165-248 84 p.

Research output: Contribution to journalArticle

Antigens
Immunity
Histocompatibility Antigens Class II
Biotechnology
Autoimmunity
51 Citations (Scopus)

Noninvasive in vivo analysis of human small intestinal paracellular absorption: Regulation by Na+-glucose cotransport

Turner, J. R., Cohen, D. E., Mrsny, R. J. & Madara, J. L., 2000, In : Digestive Diseases and Sciences. 45, 11, p. 2122-2126 5 p.

Research output: Contribution to journalArticle

Intestinal Absorption
Creatinine
Glucose
Mannitol
Rodentia
182 Citations (Scopus)

Oncogenic Raf-1 disrupts epithelial tight junctions via downregulation of occludin

Li, D. X. & Mrsny, R. J., 2000, In : The Journal of Cell Biology (JCB). 148, 4, p. 791-800 10 p.

Research output: Contribution to journalArticle

Occludin
Tight Junctions
Down-Regulation
Zonula Occludens-1 Protein
Claudin-1
3 Citations (Scopus)

Targeting macromolecular therapeutics to specific cell organelles

Keller, G. A., Li, W. & Mrsny, R. J., 2000, Controlled Drug Delivery: Designing Technologies for the Future. Park, K. & Mrsny, R. J. (eds.). Washington, DC: American Chemical Society, Vol. 752. p. 168-183 16 p. (ACS Symposium Series).

Research output: Chapter in Book/Report/Conference proceedingChapter

165 Citations (Scopus)

The coiled-coil domain of occludin can act to organize structural and functional elements of the epithelial tight junction

Nusrat, A., Chen, J. A., Foley, C. S., Liang, T. W., Tom, J., Cromwell, M., Quan, C. & Mrsny, R. J., 2000, In : Journal of Biological Chemistry. 275, 38, p. 29816-29822 7 p.

Research output: Contribution to journalArticle

Occludin
Tight Junctions
Peptides
Proteins
Phosphatidylinositol 3-Kinase