If you made any changes in Pure these will be visible here soon.

Research Output

2005

Intranasal immunization strategy to impede pilin-mediated binding of Pseudomonas aeruginosa to airway epithelial cells

Hsieh, J. C., Tham, D. M., Feng, W., Huang, F., Embaie, S., Liu, K., Dean, D., Hertle, R., Fitzgerald, D. J. & Mrsny, R. J., 2005, In : Infection and immunity. 73, 11, p. 7705-7717 13 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Mechanism of IFN- g -induced endocytosis of tight junction proteins: myosin II-dependent vacuolarization of the apical plasma membrane

Utech, M., Ivanov, A. I., Samarin, S. N., Bruewer, M., Turner, J. R., Mrsny, R. J., Parkos, C. A. & Nusrat, A., 2005, In : Molecular Biology of the Cell. 16, 10, p. 5040-5052 13 p.

Research output: Contribution to journalArticle

238 Citations (Scopus)
12 Citations (Scopus)

Multiple protein interactions involving proposed extracellular loop domains of the tight junction protein occludin

Nusrat, A., Brown, G. T., Tom, J., Drake, A., Bui, T. T., Quan, C. & Mrsny, R. J., 2005, In : Molecular Biology of the Cell. 16, 4, p. 1725-1734 10 p.

Research output: Contribution to journalArticle

56 Citations (Scopus)
29 Citations (Scopus)

The second loop of occludin is required for suppression of Raf-1induced tumor growth

Wang, Z., Mrsny, R. J. & et al, N. V., 2005, In : Oncogene. 24, 27, p. 4412-4420 9 p.

Research output: Contribution to journalArticle

53 Citations (Scopus)

Tight junctions; more than a permeability barrier

Nusrat, A. & Mrsny, R. J., 2005, In : Advanced Drug Delivery Reviews. 57

Research output: Contribution to journalArticle

2004

A perspective on current and future synthetic reflexive systems

Park, K., Yui, N. & Mrsny, R. J., 2004, Multi-Reflexive Polymers and Hydrogels: Understanding and Designing Fast-Responsive Polymeric Systems. Yui, N., Mrsny, R. & Park, K. (eds.). Boca Raton, Florida: CRC Press, p. 427-437 11 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Citation (Scopus)

Identification of hepoxilin A3 in inflammatory events: a required role in neutrophil migration across intestinal epithelia

Mrsny, R. J., Gewirtz, A. T., Siccardi, D., Savidge, T., Hurley, B. P., Madara, J. L. & McCormick, B. A., 11 May 2004, In : Proceedings of the National Academy of Sciences of the United States of America. 101, 19, p. 7421-7426 6 p.

Research output: Contribution to journalArticle

124 Citations (Scopus)

Learning from nature: examples of rapid, repetitive, responsive biological events

Mrsny, R. J., 2004, Multi-Reflexive Polymers and Hydrogels: Understanding and Designing Fast-Responsive Polymeric Systems. Yui, N., Mrsny, R. J. & Park, K. (eds.). Boca Raton, Florida: CRC Press, p. 3-15 13 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Modulation of tight junctional permeability (Preface)

Thanou, M. & Mrsny, R. J., 2004, In : Journal of Drug Targeting. 12, 2, p. 63-63 1 p.

Research output: Contribution to journalArticle

Multi-Reflexive Polymers and Hydrogels: Understanding and Designing Fast-Responsive Polymeric Systems

Yui, N. (ed.), Mrsny, R. (ed.) & Park, K. (ed.), 2004, Boca Raton, Florida: CRC Press.

Research output: Book/ReportBook

Polymorphonuclear cell transmigration induced by Pseudomonas aeruginosa requires the eicosanoid hepoxilin A 3 1

Hurley, B. P., Siccardi, D., Mrsny, R. J. & McCormick, B. A., 2004, In : The Journal of Immunology. 173, 9, p. 5712-5720 9 p.

Research output: Contribution to journalArticle

54 Citations (Scopus)

Strategies for targeting protein therapeutics to selected tissues and cells

Mrsny, R. J., 2004, In : Expert Opinion on Biological Therapy. 4, 1, p. 65-73 9 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Tight junctions - more than a permeability barrier

Thanou, M. & Mrsny, R. J., 2004, In : Journal of Drug Targeting. 12, 2, p. 63 1 p.

Research output: Contribution to journalArticle

Tissue and cell specific targeting

Mrsny, R. J., 2004, Gene Delivery: Principles and Applications. Amiji, M. M. (ed.). Boca Raton, Florida: CRC Press, p. 5-27 23 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

3 Citations (Scopus)
2003

Emerging technologies that overcome biological barriers for therapeutic protein delivery

Daugherty, A. L. & Mrsny, R. J., 2003, In : Expert Opinion on Biological Therapy. 3, 7, p. 1071-1081 11 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)
2002

A membrane-permeant peptide that inhibits MLC kinase restores barrier function in In Vitro models of intestinal disease

Zolotarevsky, Y., Hecht, G., Koutsouris, A., Gonzalez, D. E., Quan, C., Tom, J., Mrsny, R. J. & Turner, J. R., 2002, In : Gastroenterology. 123, 1, p. 163-172 10 p.

Research output: Contribution to journalArticle

272 Citations (Scopus)

Analysis methods of polysorbate 20: a new method to assess the stability of polysorbate 20 and established methods that may overlook degraded polysorbate 20

Khossravi, M., Kao, Y. H., Mrsny, R. J. & Sweeney, T. D., 2002, In : Pharmaceutical Research. 19, 5, p. 634-639 6 p.

Research output: Contribution to journalArticle

48 Citations (Scopus)

Bacterial toxins as tools for mucosal vaccination

Mrsny, R. J., Daugherty, A. L., McKee, M. L. & Fitzgerald, D. J., 2002, In : Drug Discovery Today. 7, 4, p. 247-258 12 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Cdc42 and Rac1 regulate late events in Salmonella typhimurium -induced Interleukin-8 secretion from polarizedepithelial cells

Hobert, M. E., Sands, K. A., Mrsny, R. J. & Madara, J. L., 2002, In : Journal of Biological Chemistry. 277, 52, p. 51025-51032 8 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)
2001

Dual-function vaccine for Pseudomonas aeruginosa : characterization of chimeric exotoxin A-Pilin protein

Hertle, R., Mrsny, R. & Fitzgerald, D. J., 2001, In : Infection and immunity. 69, 11, p. 6962-6969 8 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)

Emerging protein delivery methods

Cleland, J. L., Daugherty, A. & Mrsny, R., 2001, In : Current Opinion in Biotechnology. 12, p. 212-219 8 p.

Research output: Contribution to journalArticle

154 Citations (Scopus)
2000

Characterization of huJAM: evidence for involvement in cell-cell contact and tight junction regulation

Liang, T. W., Demarco, R. A., Mrsny, R. J., Gurney, A., Gray, A., Hooley, J., Aaron, H. L., Huang, A., Klassen, T., Tumas, D. B. & Fong, S., 2000, In : American Journal of Physiology - Cell Physiology. 279, 6, p. C1733-C1743

Research output: Contribution to journalArticle

85 Citations (Scopus)

Choice of microcentrifuge tubes influences T cell proliferation assay

Wei, Y., Mrsny, R., Blumberg, R. S., Fried, M. & Christ, A. D., Jul 2000, In : Biotechniques. 29, 1, p. 54-59 6 p.

Research output: Contribution to journalArticle

Controlled Drug Delivery: Designing Technologies for the Future

Park, K. (ed.) & Mrsny, R. J. (ed.), 2000, Washington, DC: American Chemical Society.

Research output: Book/ReportBook

Epithelial application of Pseudomonas aeruginosa exotoxin A results in a selective targeting to cells in the liver, spleen and lymph node

Daugherty, A. L., McKee, M. L., FitzGerald, D. J. & Mrsny, R. J., 2000, In : Journal of Controlled Release. 65, 1-2, p. 297-302 6 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Modulation of tight junction function by G protein-coupled events

Hopkins, A. M., Li, D. X., Mrsny, R. J., Walsh, S. V. & Nusrat, A., 2000, In : Advanced Drug Delivery Reviews. 41, 3, p. 329-340 12 p.

Research output: Contribution to journalArticle

51 Citations (Scopus)

New approaches to antigen delivery

FitzGerald, D. & Mrsny, R. J., 2000, In : Critical Review of Therapeutic Drug Carrier Systems. 17, 3, p. 165-248 84 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Noninvasive in vivo analysis of human small intestinal paracellular absorption: Regulation by Na+-glucose cotransport

Turner, J. R., Cohen, D. E., Mrsny, R. J. & Madara, J. L., 2000, In : Digestive Diseases and Sciences. 45, 11, p. 2122-2126 5 p.

Research output: Contribution to journalArticle

53 Citations (Scopus)

Oncogenic Raf-1 disrupts epithelial tight junctions via downregulation of occludin

Li, D. X. & Mrsny, R. J., 2000, In : The Journal of Cell Biology (JCB). 148, 4, p. 791-800 10 p.

Research output: Contribution to journalArticle

185 Citations (Scopus)

Targeting macromolecular therapeutics to specific cell organelles

Keller, G. A., Li, W. & Mrsny, R. J., 2000, Controlled Drug Delivery: Designing Technologies for the Future. Park, K. & Mrsny, R. J. (eds.). Washington, DC: American Chemical Society, Vol. 752. p. 168-183 16 p. (ACS Symposium Series).

Research output: Chapter in Book/Report/Conference proceedingChapter

3 Citations (Scopus)

The coiled-coil domain of occludin can act to organize structural and functional elements of the epithelial tight junction

Nusrat, A., Chen, J. A., Foley, C. S., Liang, T. W., Tom, J., Cromwell, M., Quan, C. & Mrsny, R. J., 2000, In : Journal of Biological Chemistry. 275, 38, p. 29816-29822 7 p.

Research output: Contribution to journalArticle

166 Citations (Scopus)