Personal profile
Research interests
I have a multidisciplinary background in pharmacy, epidemiology, and data science, and expertise in outcome-based health informatics and pharmacoepidemiology. My overarching research purpose is to develop a coordinated approach to accelerate real-world evidence using Big data to improve ageing and pioneer translational research to improve the safety of medicines in the ageing population.
As a member and key co-investigator within the Big Data and Better Ageing Research Group (along with Professor Philip Schluter and Associate Professor Hamish Jamieson (lead): https://www.otago.ac.nz/big-data-better-ageing/staff/index.html), my research has significantly impacted and advanced research in [a] improved understanding of the harmful effects of polypharmacy (application of drug burden index on big data) at a population-level, [b] quantifying multimorbidity (developed comorbidity index) in the ageing population, [c] using improved confounding methods for causal inference in observational studies, and more recently [d] using artificial intelligence to understanding clustering of multiple long-term conditions in the ageing population. In addition, my research has directly impacted patient care with a better understanding of the risks and benefits of using medicines in the ageing population.
I am interested to recruit doctoral students. Current projects on offer:
1. Development and validation of a novel anticholinergic tool to quantify anticholinergic burden.
2. Novel pharmacoepidemiological approaches to predict adverse drug reactions.
3. Measuring the impact of drug burden and polypharmacy on health outcomes in older people.
4. Artificial intelligence for identifying disease clusters in age-related multimorbidity.
5. Measuring the impact of the anticholinergic burden on health outcomes in individuals with dementia.
Education/Academic qualification
Pharmacy, Doctor of Philosophy, Impact of medication reviews on quality use of psychotropics, University of Sydney
Award Date: 18 Dec 2009
External positions
Senior Research Fellow, University of Otago
9 Oct 2018 → …
Keywords
- RM Therapeutics. Pharmacology
- RS Pharmacy and materia medica
Fingerprint
- 1 Similar Profiles
Collaborations and top research areas from the last five years
Projects
- 5 Finished
-
NERC GW4+: Leveraging Deep Learning to Uncover Hidden Patterns of Adverse Events in FAERS Data
Nishtala, P. (PI) & Babbar, R. (PI)
1/07/23 → 31/08/23
Project: Research council
-
A sense-act digital technology for the home-based care of diabetic foot ulcers
Preatoni, E. (PI), Cioroianu, I. (CoI), Ehrhardt, B. (CoI), Gurevich, D. (CoI), Kreusser, L. (CoI), Lazarus, J. (CoI), Metcalfe, B. (CoI), Nishtala, P. (CoI), Sharp, T. (CoI) & Carter, J. (Researcher)
25/02/23 → 31/07/23
Project: Research-related funding
-
Development of a digital therapeutic intervention to improve the quality of life and reduce the healthcare costs of those living with chronic diseases
Preatoni, E. (PI), Cioroianu, I. (PI), Ehrhardt, B. (PI), Gurevich, D. (PI), Kreusser, L. (PI), Lazarus, J. (PI), Metcalfe, B. (PI), Nishtala, P. (PI) & Sharp, T. (PI)
1/09/22 → 28/02/23
Project: Research-related funding
-
Artificial intelligence for identifying new disease clusters in patients with immune-mediated inflammatory conditions: A Proof-of-Concept Study
Nishtala, P. (PI), Isupova, O. (CoI), McGrogan, A. (CoI), McHugh, N. (CoI), Roy, S. (CoI), Tillett, W. (CoI) & Snowball, J. (Researcher)
National Institute for Health Research
4/01/21 → 31/12/21
Project: Central government, health and local authorities
-
Examining risks of bleeding and cardiovascular events in older people using anticoagulant and antiplatelet therapy
Nishtala, P. (PI)
1/01/15 → 31/12/15
Project: Project at a former HEI
Research output
-
Call to collaborate on data science for older people across Europe: an EuGMS Big Data Special Interest Group position paper
EuGMS Big Data Special Interest Group, 31 Oct 2025, In: European Geriatric Medicine. 16, 5, p. 1561-1565 5 p.Research output: Contribution to journal › Editorial › peer-review
-
Potentially inappropriate polypharmacy is an important predictor of 30-day emergency hospitalisation in older adults: a machine learning feature validation study
Olender, R. T., Roy, S. & Nishtala, P. S., 30 Jun 2025, In: Age and Ageing. 54, 6, afaf156.Research output: Contribution to journal › Article › peer-review
Open AccessFile68 Downloads (Pure) -
Rethinking anticholinergic burden in older adults: innovative approaches to detection and management
Phutietsile, G. O. & Nishtala, P. S., 31 Aug 2025, In: Expert Review of Clinical Pharmacology. 18, 8, p. 551-562 12 p.Research output: Contribution to journal › Review article › peer-review
Open Access -
The off-label use of psychotropic medicines in paediatric patients in Australian primary care: Off-label use of psychotropics in paediatric patients
Tanana, L., Harrison, C., Nishtala, P. S. & Chen, T. F., 30 Nov 2025, In: Psychiatry Research. 353, 116763.Research output: Contribution to journal › Article › peer-review
Open Access -
Antibiotic-Associated Acute Kidney Injury Among Older Adults: A Case-Crossover Study
Chinzowu, T., Chyou, T.-Y. & Nishtala, P. S., 29 Feb 2024, In: Clinical Drug Investigation. 44, 2, p. 131-139 9 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Link opens in a new tab Citations (SciVal)90 Downloads (Pure)
Activities
-
EuGMS Congress 2024
Nishtala, P. (Speaker)
18 Sept 2024Activity: Academic conferences and events (excluding conference publications) › Conference presentation / attendance
-
Shock dementia study shows antidepressants could actually speed up mental decline
Nishtala, P. (No value)
25 Feb 2025Activity: Media article or participation, blog › Media article or participation
-
Antidepressants Might Accelerate Dementia Decline
Nishtala, P. (No value)
26 Feb 2025Activity: Media article or participation, blog › Media article or participation
-
Why links between antidepressants and dementia should be treated with caution
Nishtala, P. (No value)
26 Feb 2025Activity: Media article or participation, blog › Media article or participation
-
Dementia: Some Antidepressants May Speed Up Decline, Neuroscientists Warn
Nishtala, P. (No value)
25 Feb 2025Activity: Media article or participation, blog › Media article or participation