Research output per year
Research output per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Dive into the research topics where Peter Sunderland is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Exploration of the nicotinamide-binding site of the tankyrases, identifying 3-arylisoquinolin-1-ones as potent and selective inhibitors in vitro
Paine, H. A., Nathubhai, A., Woon, E. C. Y., Sunderland, P. T., Wood, P. J., Mahon, M. F., Lloyd, M. D., Thompson, A. S., Haikarainen, T., Narwal, M., Lehtio, L. & Threadgill, M. D., 1 Sep 2015, In: Bioorganic and Medicinal Chemistry. 23, 17, p. 5891-5908 18 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile23 Citations (SciVal)1072 Downloads (Pure) -
Use of new and known pyridine or pyrimidine compounds, for the treatment of a disease or condition associated with tankyrase, e.g. cancer selected from e.g. breast, colon, stomach, and liver
Threadgill, M., Lloyd, M., Thompson, A., Nathubhai, A., Wood, P., Paine, H., Kumpan, E., Sunderland, P. & Woon, E. C. Y., 2014, Patent No. WO2014087165-A1Research output: Patent
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One-pot tandem Hurtley–retro-Claisen–cyclisation reactions in the synthesis of 3-substituted analogues of 5-aminoisoquinolin-1-one (5-AIQ), a water-soluble inhibitor of PARPs
Woon, E. C. Y., Sunderland, P. T., Paine, H. A., Lloyd, M. D., Thompson, A. S. & Threadgill, M. D., 1 Sep 2013, In: Bioorganic and Medicinal Chemistry. 21, 17, p. 5218-5227 10 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile18 Citations (SciVal)186 Downloads (Pure) -
5-benzamidoisoquinolin-1-ones and 5-(ω-carboxyalkyl)isoquinolin-1-ones as isoform-selective inhibitors of poly(ADP-ribose) polymerase 2 (PARP-2)
Sunderland, P. T., Woon, E. C. Y., Dhami, A., Bergin, A. B., Mahon, M. F., Wood, P. J., Jones, L. A., Tully, S. R., Lloyd, M. D., Thompson, A. S., Javaid, H., Martin, N. M. B. & Threadgill, M. D., 2011, In: Journal of Medicinal Chemistry. 54, 7, p. 2049-2059 11 p.Research output: Contribution to journal › Article › peer-review
File40 Citations (SciVal)311 Downloads (Pure) -
Synthesis of 4-alkyl-, 4-aryl- and 4-arylamino-5-aminoisoquinolin-1-ones and identification of a new PARP-2 selective inhibitor
Sunderland, P. T., Dhami, A., Mahon, M. F., Jones, L. A., Tully, S. R., Lloyd, M. D., Thompson, A. S., Javaid, H., Martin, N. M. B. & Threadgill, M. D., 7 Feb 2011, In: Organic and Biomolecular Chemistry. 9, 3, p. 881-891 11 p.Research output: Contribution to journal › Article › peer-review
File14 Citations (SciVal)190 Downloads (Pure)
Thesis
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Design and synthesis of selective inhibitors of poly(ADP-ribose)polymerase-2
Author: Sunderland, P., 1 Jan 2010Supervisor: Threadgill, M. (Supervisor), Thompson, A. (Supervisor) & Martin, N. G. (External person) (Supervisor)
Student thesis: Doctoral Thesis › PhD
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