Research output per year
Research output per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Dive into the research topics where Peter Sunderland is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Exploration of the nicotinamide-binding site of the tankyrases, identifying 3-arylisoquinolin-1-ones as potent and selective inhibitors in vitro
Paine, H. A., Nathubhai, A., Woon, E. C. Y., Sunderland, P. T., Wood, P. J., Mahon, M. F., Lloyd, M. D., Thompson, A. S., Haikarainen, T., Narwal, M., Lehtio, L. & Threadgill, M. D., 1 Sept 2015, In: Bioorganic and Medicinal Chemistry. 23, 17, p. 5891-5908 18 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile27 Citations (SciVal)1092 Downloads (Pure) -
TANKYRASE INHIBITORS
Threadgill, M. D., Lloyd, M. D., Thompson, A. S., Nathubhai, A., Wood, P. J., Paine, H. A., Kumpan, E., Sunderland, P. T. & Chue Yen Woon, E., 12 Jun 2014, IPC No. C07D471/04, A61K31/4375, Patent No. WO2014087165, Priority date 6 Dec 2012, Priority No. GB201221971AResearch output: Patent
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Use of new and known pyridine or pyrimidine compounds, for the treatment of a disease or condition associated with tankyrase, e.g. cancer selected from e.g. breast, colon, stomach, and liver
Threadgill, M., Lloyd, M., Thompson, A., Nathubhai, A., Wood, P., Paine, H., Kumpan, E., Sunderland, P. & Woon, E. C. Y., 2014, Patent No. WO2014087165-A1Research output: Patent
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One-pot tandem Hurtley–retro-Claisen–cyclisation reactions in the synthesis of 3-substituted analogues of 5-aminoisoquinolin-1-one (5-AIQ), a water-soluble inhibitor of PARPs
Woon, E. C. Y., Sunderland, P. T., Paine, H. A., Lloyd, M. D., Thompson, A. S. & Threadgill, M. D., 1 Sept 2013, In: Bioorganic and Medicinal Chemistry. 21, 17, p. 5218-5227 10 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile21 Citations (SciVal)202 Downloads (Pure) -
5-benzamidoisoquinolin-1-ones and 5-(ω-carboxyalkyl)isoquinolin-1-ones as isoform-selective inhibitors of poly(ADP-ribose) polymerase 2 (PARP-2)
Sunderland, P. T., Woon, E. C. Y., Dhami, A., Bergin, A. B., Mahon, M. F., Wood, P. J., Jones, L. A., Tully, S. R., Lloyd, M. D., Thompson, A. S., Javaid, H., Martin, N. M. B. & Threadgill, M. D., 2011, In: Journal of Medicinal Chemistry. 54, 7, p. 2049-2059 11 p.Research output: Contribution to journal › Article › peer-review
File46 Citations (SciVal)333 Downloads (Pure)
Thesis
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Design and synthesis of selective inhibitors of poly(ADP-ribose)polymerase-2
Author: Sunderland, P., 1 Jan 2010Supervisor: Threadgill, M. (Supervisor), Thompson, A. (Supervisor) & Martin, N. G. (External person) (Supervisor)
Student thesis: Doctoral Thesis › PhD
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