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Personal profile

Research interests

Dr Estrela’s research focuses on the development of label-free electrical biosensors and chemical sensors for a wide range of applications such as medical diagnostics and environmental monitoring.

Dr Estrela research interests include

  • label-free electrical detection of biomolecular interactions
  • biologically sensitive field-effect devices
  • detection of DNA, proteins, bacteria, cells, ions and small molecules
  • electrochemical impedance spectroscopy of biological systems
  • use of solid state devices in aqueous environments
  • surface biofunctionalization
  • electronic addressing of microarrays
  • nanobiosensors
  • microfluidics

Dr Estrela’s work has a strong multidisciplinary nature and he has collaborations in place with electrical engineers, physicists, chemists, molecular biologists, chemical engineers, pharmacologists, clinicians and industry.

Willing to supervise PhD


Education/Academic qualification

Doctor of Philosophy, University of Amsterdam

Master of Physics, University of Lisbon


  • TK Electrical engineering. Electronics Nuclear engineering
  • Biosensors
  • QD Chemistry
  • Electrochemical sensors
  • Biosensors
  • Biosensing Technologies
  • Bioengineering
  • Electrochemistry
  • Sensors
  • Nanobiosensors
  • Bioelectronics

Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

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Biosensors Chemical Compounds
Labels Chemical Compounds
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Prostate-Specific Antigen Chemical Compounds
Gold Chemical Compounds
DNA Engineering & Materials Science
Antigens Engineering & Materials Science
Electrochemical impedance spectroscopy Chemical Compounds

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Projects 2009 2020


Estrela, P.


Project: Research council

public health
early warning system
health status
infectious disease

Evaluation of Next Generation Receptor Technologies in OTFT Biosensors

Estrela, P.


Project: Central government, health and local authorities

Biosensing Techniques
Primary Health Care
Point-of-Care Systems
Emergency Medical Services

Research Output 1994 2019

A PNA-based Lab-on-PCB diagnostic platform for rapid and high sensitivity DNA quantification

Jolly, P., Rainbow, J., Regoutz, A., Estrela, P. & Moschou, D., 1 Jan 2019, In : Biosensors and Bioelectronics. 123, p. 244-250 7 p.

Research output: Contribution to journalArticle

Peptide Nucleic Acids
Polychlorinated Biphenyls
Polychlorinated biphenyls
Biosensing Techniques
1 Citation (Scopus)
Glutamate Dehydrogenase
Biosensing Techniques
Plasmodium falciparum
Field effect transistors

Electrochemical Aptasensor using Optimized Surface Chemistry for the Detection of Mycobacterium tuberculosis Secreted Protein MPT64 in Human Serum

Sypabekova, M., Jolly, P., Estrela, P. & Kanayeva, D., 1 Jan 2019, In : Biosensors and Bioelectronics. 123, p. 141-151 11 p.

Research output: Contribution to journalArticle

Surface chemistry
Artificial Receptors
1 Citation (Scopus)

Extracellular Electrophysiology in the Prostate Cancer Cell Model PC-3

Cabello, M., Ge, H., Aracil, C., Moschou, D., Estrela, P., Quero, J. M., Pascu, S. & Rocha, P., 1 Jan 2019, In : Sensors. 19, 1, 11 p., 139.

Research output: Contribution to journalArticle

Open Access

Gold interdigitated triple-microelectrodes for label-free prognosticative aptasensing of prostate cancer biomarker in serum

Ibau, C., Md Arshad, K., Gopinath, S., Nuzaihan, M., Fathil, M. & Estrela, P., 26 Apr 2019, In : Biosensors and Bioelectronics. 136, p. 118-127 10 p.

Research output: Contribution to journalArticle


A Study of Multichannel Open Circuit Potentiometry in Biosensor Applications

Author: Wong, L. C. C., 20 Jun 2018

Supervisor: Estrela, P. (Supervisor)

Student thesis: Doctoral ThesisPhD


A study on the optimisation of electrochemical impedance spectroscopy biosensors

Author: Formisano, N., 24 Feb 2016

Supervisor: Estrela, P. (Supervisor) & Taylor, J. (Supervisor)

Student thesis: Doctoral ThesisPhD


Biosensors for drug discovery applications

Author: Bhalla, N., 6 Jan 2016

Supervisor: Estrela, P. (Supervisor), Di Lorenzo, M. (Supervisor) & Pula, G. (Supervisor)

Student thesis: Doctoral ThesisPhD


Electrochemical detection of cancer biomarkers

Author: Zhurauski, P., 13 Dec 2017

Supervisor: Estrela, P. (Supervisor)

Student thesis: Doctoral ThesisMPhil


Investigations into New Functionalised Thiosemicarbazones and Related Carbon Nanohybrids for the Imaging of Prostate Cancer

Author: Cortezon Tamarit, F., 1 Mar 2017

Supervisor: Pascu, S. (Supervisor), Estrela, P. (Supervisor), Tyrrell, R. (Supervisor) & Frost, C. (Supervisor)

Student thesis: Doctoral ThesisPhD