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Paul Mitchell

Dr

  • 5 WEST 3.31

20022019

Research output per year

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Personal profile

Research interests

Application of ethological techniques to the analysis of rodent non-social, social and agonistic behaviour, and the effect(s) of psychotropic drug treatment (in particular antidepressants,anxiolytics, antipsychotics and psychostimulants) thereon.

Current lab members

Dr Pauline Wood - development of in vitro and ex vivo techniques (in situ autoradiography, immunohistochemistry, in situ hybridisation, PCR, Western blot) to examine adaptive changes of serotonin receptor subtypes induced by chronic psychotropic drug treatment.

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Research Output

Identification of novel small-molecule inhibitors of α-methylacyl-CoA racemase (AMACR; P504S) and structure-activity relationships

Petrova, Y., Wadda, K., Nathubhai, A., Jevglevskis, M., Mitchell, P., James, T., Threadgill, M., Woodman, T. & Lloyd, M., 1 Nov 2019, In : Bioorganic Chemistry. 92, 103264.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Novel 2-arylthiopropanoyl-CoA inhibitors of α-methylacyl-CoA racemase 1A (AMACR; P504S) as potential anti-prostate cancer agents

Jevglevskis, M., Nathubhai, A., Wadda, K., Lee, G. L., Al-Rawi, S., Jiao, T., Mitchell, P., James, T., Threadgill, M., Woodman, T. & Lloyd, M., 1 Nov 2019, In : Bioorganic Chemistry. 92, 103263.

Research output: Contribution to journalArticle

Open Access
File
66 Downloads (Pure)

Chronic treatment with 13-cis-retinoic acid changes aggressive behaviours in the resident-intruder paradigm in rats

Trent, S., Drew, C. J. G., Mitchell, P. J. & Bailey, S. J., Dec 2009, In : European Neuropsychopharmacology. 19, 12, p. 876-886 11 p.

Research output: Contribution to journalArticle

Open Access
File
  • 18 Citations (Scopus)
    139 Downloads (Pure)

    Antidepressant-like effects of the novel, selective, 5-HT 2C receptor agonist WAY-163909 in rodents

    Rosenzweig-Lipson, S., Sabb, A., Stack, G., Mitchell, P. J., Lucki, I., Malberg, J. E., Grauer, S., Brennan, J., Cryan, J. F., Sukoff Rizzo, S. J., Dunlop, J., Barrett, J. E. & Marquis, K. L., 2007, In : Psychopharmacology. 192, p. 159-170 12 p.

    Research output: Contribution to journalArticle

    76 Citations (Scopus)

    Animal models of depression

    Willner, P., Mitchell, P. J. & Koch, M., 2006, Animal Models of Neuropsychiatric Diseases. London: Imperial College Press, p. 223-292 70 p.

    Research output: Chapter in Book/Report/Conference proceedingChapter

    1 Citation (Scopus)