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Paul Mitchell

Dr

  • 5 WEST 3.31

20022019
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Personal profile

Research interests

Application of ethological techniques to the analysis of rodent non-social, social and agonistic behaviour, and the effect(s) of psychotropic drug treatment (in particular antidepressants,anxiolytics, antipsychotics and psychostimulants) thereon.

Current lab members

Dr Pauline Wood - development of in vitro and ex vivo techniques (in situ autoradiography, immunohistochemistry, in situ hybridisation, PCR, Western blot) to examine adaptive changes of serotonin receptor subtypes induced by chronic psychotropic drug treatment.

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  • 1 Similar Profiles
Isotretinoin Medicine & Life Sciences
Psychotropic Drugs Medicine & Life Sciences
Retinoids Medicine & Life Sciences
Tretinoin Medicine & Life Sciences
Antidepressive Agents Medicine & Life Sciences
Agonistic Behavior Medicine & Life Sciences
Social Behavior Medicine & Life Sciences
Serotonin Receptors Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 2002 2019

Identification of novel small-molecule inhibitors of α-methylacyl-CoA racemase (AMACR; P504S) and structure-activity relationships

Petrova, Y., Wadda, K., Nathubhai, A., Jevglevskis, M., Mitchell, P., James, T., Threadgill, M., Woodman, T. & Lloyd, M., 1 Nov 2019, In : Bioorganic Chemistry. 92, 103264.

Research output: Contribution to journalArticle

10 Downloads (Pure)

Novel 2-arylthiopropanoyl-CoA inhibitors of α-methylacyl-CoA racemase 1A (AMACR; P504S) as potential anti-prostate cancer agents

Jevglevskis, M., Nathubhai, A., Wadda, K., Lee, G. L., Al-Rawi, S., Jiao, T., Mitchell, P., James, T., Threadgill, M., Woodman, T. & Lloyd, M., 1 Nov 2019, In : Bioorganic Chemistry. 92, 103263.

Research output: Contribution to journalArticle

Open Access
File
16 Citations (Scopus)
87 Downloads (Pure)

Chronic treatment with 13-cis-retinoic acid changes aggressive behaviours in the resident-intruder paradigm in rats

Trent, S., Drew, C. J. G., Mitchell, P. J. & Bailey, S. J., Dec 2009, In : European Neuropsychopharmacology. 19, 12, p. 876-886 11 p.

Research output: Contribution to journalArticle

Open Access
File
Isotretinoin
Retinoids
Tretinoin
Acne Vulgaris
Vitamin A

Antidepressant-like effects of the novel, selective, 5-HT 2C receptor agonist WAY-163909 in rodents

Rosenzweig-Lipson, S., Sabb, A., Stack, G., Mitchell, P. J., Lucki, I., Malberg, J. E., Grauer, S., Brennan, J., Cryan, J. F., Sukoff Rizzo, S. J., Dunlop, J., Barrett, J. E. & Marquis, K. L., 2007, In : Psychopharmacology. 192, p. 159-170 12 p.

Research output: Contribution to journalArticle

Animal models of depression

Willner, P., Mitchell, P. J. & Koch, M., 2006, Animal Models of Neuropsychiatric Diseases. London: Imperial College Press, p. 223-292 70 p.

Research output: Chapter in Book/Report/Conference proceedingChapter