Nikoletta Fotaki

Search results

• 2025

  Drug–Drug Interaction Between Dihydroartemisinin–Piperaquine and Sulfadoxine-Pyrimethamine During Malaria Chemoprevention in Pregnant Women

  Mwebaza, N., Roh, M. E., Geng, Y. Z., Opio, L., Opira, B., Marzan, F., Mwima, M. W., Ssemukuye, T., Guo, K., Gingrich, D., Fotaki, N., Kakuru, A., Kizza, J., Aguti, M., Adrama, H., Kamya, M., Dorsey, G., Rosenthal, P. J., Aweeka, F. T. & Huang, L., 28 Feb 2025, In: Clinical Pharmacology and Therapeutics. 117, 2, p. 506-514

  Research output: Contribution to journal › Article › peer-review

  • Pyrimethamine Plus Sulfadoxine 100%
  • Sulfadoxine 15%
  • Pyrimethamine 15%
  • Piperaquine 7%
• 2024

  Assessing the Anticholinergic Cognitive Burden Classification of Putative Anticholinergic Drugs Using Drug Properties

  Nishtala, P., Fotaki, N. & Phutietsile, G., 30 Sept 2024, In: British Journal Of Clinical Pharmacology. 90, 9, p. 2236-2255 20 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Cholinergic Receptor Blocking Agent 100%
  • Blood-Brain Barrier 36%
  • Bioavailability 9%
  • Drug Distribution 9%
  • P-Glycoprotein 9%

• Biopharmaceutical tools for de-risking paediatric formulation development.

  Murshed, M. & Fotaki, N., 23 Oct 2024.

  Research output: Contribution to conference › Poster › peer-review

• Biopharmaceutics modelling to explore target dissolution profiles of long acting injectable suspensions

  Cleary , H., Fotaki, N. & D'Arcy, D. M., 6 Sept 2024.

  Research output: Contribution to conference › Poster › peer-review

• Exploring Particle Behaviour during Dissolution Testing of Long-Acting Injectable Suspensions - A Potential Role for Image Analysis

  Cleary , H., Persoons , T., Fotaki, N. & D’arcy, D., 23 Oct 2024.

  Research output: Contribution to conference › Poster › peer-review

• Integration of Gut Microbiome Metabolism in a PBBM-PBPK Model: its impact on the Sulfasalazine absorption

  Plait , F., Silva , D., Zhou, H., Fotaki, N., Garrastazu Pereira, G. & Lukacova, V., 23 Oct 2024.

  Research output: Contribution to conference › Poster › peer-review

• In Vitro Product Performance Testing of Oral Drug Products: View of the USP Expert Panel

  Fotaki, N., D’arcy, D., Demuth, J., Hermans, A., Lu, X., Nir, I., Scheubel, E., Skwierczynski, R. & Hernandez-Cardoso, A., 31 Aug 2024, In: Dissolution Technologies. 31, 3, p. 110-121 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Route of Administration 100%
  • Nanomaterial 100%
  • In Vitro 100%

• Parameterization of Physiologically Based Biopharmaceutics Models: Workshop Summary Report

  Pepin, X., Arora, S., Borges, L., Cano-Vega, M., Carducci, T., Chatterjee, P., Chen, G., Cristofoletti, R., Dallmann, A., Delvadia, P., Dressman, J., Fotaki, N., Gray, E., Heimbach, T., Holte, Ø., Kijima, S., Kotzagiorgis, E., Lennernäs, H., Lindahl, A. & Loebenberg, R. & 20 others, Mackie, C., Malamatari, M., McAllister, M., Mitra, A., Moody, R., Mudie, D., Musuamba Tshinanu, F., Polli, J. E., Rege, B., Ren, X., Rullo, G., Scherholz, M., Song, I., Stillhart, C., Suarez-Sharp, S., Tannergren, C., Tsakalozou, E., Veerasingham, S., Wagner, C. & Seo, P., 5 Aug 2024, In: Molecular Pharmaceutics. 21, 8, p. 3697-3731 35 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Pharmaceutics 100%
  • Excipient 14%
  • Base 14%
  • Drug Solubility 14%
  6 Citations (SciVal)

• SUBQ environment impact on in-vitro drug release of PLGA microspheres

  Frigerio , G., Gridley, K., Mrsny, R., Selmin, F. & Fotaki, N., 23 Oct 2024.

  Research output: Contribution to conference › Poster › peer-review

• Testing the In Vitro Product Performance of Inhalation and Nasal Drug Products: Views of the USP Expert Panel

  Sakagami, M. & Fotaki, N., 30 Nov 2024, In: Dissolution Technologies. 31, 4, p. 162-172 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • In Vitro 100%
  • Exhalation 100%
  • Drug Device Combination Product 100%
  • Pharmacokinetics 33%
  • Systemic Disease 33%
  1 Citation (SciVal)

• Thermal stabilisation of lysozyme through ensilication

  Abdulkareem, R., Doekhie, A., Fotaki, N., Koumanov, F., Dodson, C. & Sartbaeva, A., 30 Sept 2024, In: Molecules. 29, 17, 4207.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Lysozyme 100%
  • Enzyme 100%
  • Buffer 75%
  • Silicon Dioxide 25%
  • Therapeutic Vaccine 25%

• Using PBBM to Establish In Vitro-In Vivo Relationship for Budesonide Delayed Release Oral Drug Product

  Silva , D., Zhou, H., Wu , F., Fotaki, N., Garrastazu Pereira, G. & Lukacova, V., 23 Oct 2024.

  Research output: Contribution to conference › Poster › peer-review
• 2023

  A review of paediatric injectable drug delivery to inform the study of product acceptability – An introduction

  Ruiz, F., Nunn, A., Gill, A., Clapham, D., Fotaki, N., Salunke, S., Cram, A. & O'Brien, F., 1 Jul 2023, In: European Journal of Pharmaceutics and Biopharmaceutics. 188, p. 265-270 6 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Pediatrics 100%
  • Intramuscular Injection 100%
  • Drug Administration Route 100%
  • Subcutaneous Injection 100%
  • Medicine 50%
  4 Citations (SciVal)

• Physiologically based biopharmaceutics model (PBBM) of minimally absorbed locally acting drugs in the gastrointestinal tract - case study: Tenapanor

  Stamatopoulos, K., Mistry, N., Fotaki, N., Turner, D. B. & Swift, B., 31 Dec 2023, In: Pharmaceutics. 15, 12, 16 p., 2726.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Gastrointestinal Tract 100%
  • Tenapanor 100%
  • Pharmaceutics 100%
  • Food Intake 25%
  • Pharmacodynamics 25%
  1 Citation (SciVal)

• Report on the Virtual Workshop: A Quest for Biowaiver, Including Next Generation Dissolution Characterization and Modeling

  Srebro, J., Abend, A., Dorożyński, P., Fotaki, N., Garbacz, G., Gray, V. A., Mann, J., Marques, M. R., Mendyk, A., Pepin, X., Polak, S. & Suarez-Sharp, S., 1 May 2023, In: Dissolution Technologies. 30, 2, p. 100-108 9 p.

  Research output: Contribution to journal › Article

  Open Access

  • Characterization 100%
  1 Citation (SciVal)

• The association between anticholinergic burden and mobility: a systematic review and meta-analyses

  Phutietsile, G. O., Fotaki, N., Jamieson, H. A. & Nishtala, P. S., 23 Mar 2023, In: BMC Geriatrics. 23, 1, 161.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Cholinergic Receptor Blocking Agent 100%
  • Polypharmacy 15%
  • Observational Study 7%
  9 Citations (SciVal)

• Usefulness of the Beagle Model in the Evaluation of Paracetamol and Ibuprofen Exposure after Oral Administration to Pediatric Populations: An Exploratory Study

  Statelova, M., Holm, R., Fotaki, N., Reppas, C. & Vertzoni, M., 5 Jun 2023, In: Molecular Pharmaceutics. 20, 6, p. 2836-2852 17 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Paracetamol 100%
  • Ibuprofen 100%
  • Beagle 100%
  • Infant Formula 20%
  • Bioavailability 10%
  3 Citations (SciVal)

  82 Downloads (Pure)
• 2022

  Biopharmaceutics Tools for Rational Formulation Design

  Zarmpi, P., McAllister, M., Butler, J. & Fotaki, N., 2022, Biopharmaceutics: From Fundamentals to Industrial Practice. Batchelor, H. (ed.). John Wiley & Sons

  Research output: Chapter or section in a book/report/conference proceeding › Book chapter

• Oral administration of buparvaquone nanostructured lipid carrier enables in vivo activity against Leishmania infantum

  Monteiro, L. M., Löbenberg, R., Barbosa, E. J., de Araujo, G. L. B., Sato, P. K., Kanashiro, E., de Araujo Eliodoro, R. H., Rocha, M., de Freitas, V. L. T., Fotaki, N. & Bou-Chacra, N. A., 1 Feb 2022, In: European Journal of Pharmaceutical Sciences . 169, p. 106097 1 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Buparvaquone 100%
  • Leishmania infantum 100%
  • Leishmaniasis 28%
  • Adverse Event 14%
  • Biocompatibility 14%
  9 Citations (SciVal)

• Performance Evaluation of Montelukast Pediatric Formulations: Part I—Age-Related In Vitro Conditions

  Guimarães, M., Somville, P., Vertzoni, M. & Fotaki, N., 10 Jan 2022, In: AAPS Journal. 24, 1, 26.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Montelukast 100%
  • Liquid 25%
  • Gastrointestinal Tract 25%
  • Tablet 16%
  • Pharmaceutics 16%
  3 Citations (SciVal)

• Performance Evaluation of Montelukast Pediatric Formulations: Part II — a PBPK Modelling Approach

  Guimarães, M., Vertzoni, M. & Fotaki, N., 10 Jan 2022, In: AAPS Journal. 24, 1, 27.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Physiologically Based Pharmacokinetic Modelling 100%
  • Montelukast 100%
  • Pharmacokinetics 80%
  • Drug Development 20%
  • Tablet 20%
  5 Citations (SciVal)

• Understanding the impact of age-related changes in pediatric GI solubility by multivariate data analysis

  Guimarães, M., Maharaj, A., Edginton, A., Vertzoni, M. & Fotaki, N., 4 Feb 2022, In: Pharmaceutics. 14, 2, 356.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Drug Solubility 100%
  • Drug Solubilisation 100%
  • Drug Development 33%
  • Phenobarbital 33%
  • Lipophilicity 33%
  1 Citation (SciVal)
• 2021

  Affinity of Lipophilic Drugs to Mixed Lipid Aggregates in Simulated Gastrointestinal Fluids

  Fagerberg, J. H., Zarmpi, P., Jabbar, H. & Fotaki, N., 1 Jan 2021, In: Journal of Pharmaceutical Sciences. 110, 1, p. 186-197 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Lipophilicity 100%
  • Bile Salt 100%
  • Bioavailability 33%
  • Phospholipid 33%
  • Bioequivalence 33%
  4 Citations (SciVal)

  87 Downloads (Pure)

• Current challenges and future perspectives in oral absorption research: An opinion of the UNGAP network

  Vinarov, Z., Abrahamsson, B., Artursson, P., Batchelor, H., Berben, P., Bernkop-Schnürch, A., Butler, J., Ceulemans, J., Davies, N., Dupont, D., Flaten, G. E., Fotaki, N., Griffin, B. T., Jannin, V., Keemink, J., Kesisoglou, F., Koziolek, M., Kuentz, M., Mackie, A. & Meléndez Martinez, A. J. & 16 others, McAllister, M., Müllertz, A., O'Driscoll, C. M., Parrott, N., Paszkowska, J., Pavek, P., Porter, C. J. H., Reppas, C., Stillhart, C., Sugano, K., Toader, E., Valentová, K., Vertzoni, M., De Wildt, S., Wilson, C. G. & Augustijns, P., 30 Apr 2021, In: Advanced Drug Delivery Reviews. 171, p. 289-331 43 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Oral Absorption 100%
  • Drug Absorption 100%
  • Drug Development 50%
  • Drug Discovery 50%
  • Drug Interaction 50%
  104 Citations (SciVal)

• Evaluating pediatric and adult simulated fluids solubility: Abraham solvation parameters and multivariate analysis

  Guimarães, M., Kuentz, M., Vertzoni, M. & Fotaki, N., 30 Nov 2021, In: Pharmaceutical Research. 38, 11, p. 1889-1896 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Drug Solubility 100%
  • Surfactant 16%
  • Drug Solubilisation 16%
  1 Citation (SciVal)

• Gastric Emptying

  Zarmpi, P. & Fotaki, N., 2021, The ADME Encyclopedia. Talevi, A. (ed.). Springer

  Research output: Chapter or section in a book/report/conference proceeding › Book chapter

• Gut Microbiota: Impact on Pharmacokinetics

  Zarmpi, P. & Fotaki, N., 2021, The ADME Encyclopedia. Talevi, A. (ed.). Springer

  Research output: Chapter or section in a book/report/conference proceeding › Book chapter

• Highlights from the 2020 AAPS 360 annual meeting

  Gray, V. A., Diaz, D. A., Dressman, J., Tsume, Y. & Fotaki, N., 31 May 2021, In: Dissolution Technologies. 28, 2, p. 36-40 5 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Annuals 100%
  • Americans 100%
  2 Citations (SciVal)

• Investigating the critical variables of azithromycin oral absorption using in vitro tests and PBPK Modeling

  Guimaraes Sa Correia, M., Somville, P., Vertzoni, M. & Fotaki, N., 31 Dec 2021, In: Journal of Pharmaceutical Sciences. 110, 12, p. 3874-3888 15 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Azithromycin 100%
  • Normal Human 11%
  • Buffer 11%
  • Drug Absorption 11%
  • Pharmaceutics 11%
  6 Citations (SciVal)

  317 Downloads (Pure)

• Investigating the Impact of Crohn's Disease on the Bioaccessibility of a Lipid-Based Formulation with an in Vitro Dynamic Gastrointestinal Model

  Effinger, A., Mcallister, M., Tomaszewska, I., O'Driscoll, C. M., Taylor, M., Gomersall, S., Heaton, J., Smith, K. L., Sarcevica, I., Young, S. L. & Fotaki, N., 5 Apr 2021, In: Molecular Pharmaceutics. 18, 4, p. 1530-1543 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Bile Salt 100%
  • Crohn's Disease 100%
  • Phase Composition 100%
  • Ciprofloxacin 75%
  • Fatty Acids 50%
  10 Citations (SciVal)

  165 Downloads (Pure)

• In vitro in vivo relations for the parenteral liposomal formulation of Amphotericin B: A biorelevant and clinically relevant approach

  Díaz de León–Ortega, R., D'Arcy, D. M., Lamprou, D. A., Xue, W. F. & Fotaki, N., 28 Feb 2021, In: European Journal of Pharmaceutics and Biopharmaceutics. 159, p. 188-197

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Buffer 100%
  • Amphotericin B 100%
  • In Vitro 100%
  • In Vivo 100%
  • Normal Human 66%
  6 Citations (SciVal)

  94 Downloads (Pure)

• In vitro - in vivo relations for the parenteral liposomal formulation of Amphotericin B: A clinically relevant approach with PBPK modeling

  Díaz de León–Ortega, R., D'Arcy, D. M., Lamprou, D. A. & Fotaki, N., 28 Feb 2021, In: European Journal of Pharmaceutics and Biopharmaceutics. 159, p. 177-187

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Amphotericin B 100%
  • Physiologically Based Pharmacokinetic Modelling 100%
  • Pharmacokinetics 100%
  • In Vitro Release 80%
  • Blood Level 60%
  1 Citation (SciVal)

  40 Downloads (Pure)

• Migrating Motor Complex

  Zarmpi, P. & Fotaki, N., 2021, The ADME Encyclopedia. Talevi, A. (ed.).

  Research output: Chapter or section in a book/report/conference proceeding › Book chapter

• Oral Drug Delivery and Food-drug Interactions

  Zarmpi, P. & Fotaki, N., 2021, The ADME Encyclopedia. Talevi, A. (ed.). Springer

  Research output: Chapter or section in a book/report/conference proceeding › Book chapter

• Predicting budesonide performance in healthy subjects and patients with Crohn's disease using biorelevant in vitro dissolution testing and PBPK modeling

  Effinger, A., O'Driscoll, C. M., McAllister, M. & Fotaki, N., 1 Feb 2021, In: European Journal of Pharmaceutical Sciences. 157, 105617.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Normal Human 100%
  • Budesonide 100%
  • Crohn's Disease 100%
  • Physiologically Based Pharmacokinetic Modelling 100%
  • Pharmacokinetics 45%
  15 Citations (SciVal)

  141 Downloads (Pure)
• 2020

  American association of pharmaceutical scientists (AAPS) and Chinese national institutes for food and drug control (NIFDC) joint workshop on dissolution, bioequivalence, product performance, and quality

  Lu, X., Ning, B., Fotaki, N., Sharp, S. S., Burgess, D. & Haddouchi, S., 1 Jan 2020, In: Dissolution Technologies. 27, 2, p. 42-50 9 p.

  Research output: Contribution to journal › Book/Film/Article review › peer-review

  Open Access

  • China 100%
  • Americans 100%
  • Bioequivalence 100%
  1 Citation (SciVal)

• A new medium-throughput screening design approach for the development of hydroxymethylnitrofurazone (NFOH) nanostructured lipid carrier for treating leishmaniasis

  de Souza, A., Yukuyama, M. N., Barbosa, E. J., Monteiro, L. M., Faloppa, A. C. B., Calixto, L. A., de Barros Araújo, G. L., Fotaki, N., Löbenberg, R. & Bou-Chacra, N. A., 1 Sept 2020, In: Colloids and Surfaces B: Biointerfaces. 193, 111097.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Leishmaniasis 100%
  • Bioavailability 25%
  • Dimethyl Sulfoxide 25%
  • High Performance Liquid Chromatography 25%
  • Differential Scanning Calorimetry 25%
  11 Citations (SciVal)

  180 Downloads (Pure)

• BCS-based biowaivers: extension to paediatrics

  Martir, J., Flanagan, T., Mann, J. & Fotaki, N., 1 Dec 2020, In: European Journal of Pharmaceutical Sciences. 155, 105549.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Drug Solubility 100%
  • Prednisolone 100%
  • Amoxicillin 50%
  • Bioequivalence 50%
  • Clinical Study 50%
  5 Citations (SciVal)

  128 Downloads (Pure)

• Biopharmaceutical implications of excipient variability on drug dissolution from immediate release products

  Zarmpi, P., Flanagan, T., Meehan, E., Mann, J., Østergaard, J. & Fotaki, N., 1 Sept 2020, In: European Journal of Pharmaceutics and Biopharmaceutics. 154, p. 195-209 15 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Excipient 100%
  • Tablet 55%
  • Magnesium Stearate 33%
  • Starch Glycolate Sodium 22%
  • Particle-Size Distribution 11%
  21 Citations (SciVal)

  240 Downloads (Pure)

• Biopharmaceutical understanding of excipient variability on drug apparent solubility based on drug physicochemical properties. Case study: Hypromellose (HPMC)

  Zarmpi, P., Flanagan, T., Meehan, E., Mann, J. & Fotaki, N., 2020, In: AAPS Journal. 22, 49.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Excipient 100%
  • Hydroxypropylmethylcellulose 100%
  • Bioavailability 16%
  • Drug Formulation 16%
  • Lipophilicity 16%
  26 Citations (SciVal)

• Biopharmaceutical understanding of excipient variability on drug apparent solubility based on drug physicochemical properties. Case study: Superdisintegrants

  Zarmpi, P., Flanagan, T., Meehan, E., Mann, J. & Fotaki, N., 31 Mar 2020, In: AAPS Journal. 22, 2, 46.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Excipient 100%
  • Drug Solubility 33%
  • Bioavailability 22%
  • Dosage Forms 22%
  • Tablet 11%

• Co-administration of Paediatric Medicines with Food and Drinks in the Context of Their Physicochemical Properties—a Global Perspective on Practices and Recommendations

  Martir, J., Flanagan, T., Mann, J. & Fotaki, N., 4 Mar 2020, In: AAPS Journal. 22, 2, 54.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Drug Formulation 100%
  • Drug Development 100%
  • Statistical Model 100%
  14 Citations (SciVal)

• Development of an Aerosol Dose Collection Apparatus for In Vitro Dissolution Measurements of Orally Inhaled Drug Products

  Price, R., Shur, J., Ganley, W., Farias, G., Fotaki, N., Conti, D. S., Delvadia, R., Absar, M., Saluja, B. & Lee, S., 31 Mar 2020, In: AAPS Journal. 22, 2, 47.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Dry Powder Inhaler 100%
  • Metered-Dose Inhaler 66%
  • Fluticasone Propionate 33%
  • Sodium Dodecyl Sulfate 33%
  • Sodium Dihydrogen Phosphate 33%
  23 Citations (SciVal)

• Establishing virtual bioequivalence and clinically relevant specifications using in vitro biorelevant dissolution testing and physiologically-based population pharmacokinetic modeling. Case example: Naproxen

  Loisios-Konstantinidis, I., Cristofoletti, R., Fotaki, N., Turner, D. B. & Dressman, J., 15 Feb 2020, In: European Journal of Pharmaceutical Sciences. 143, 105170.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Bioequivalence 100%
  • Naproxen 100%
  • Pharmacokinetic Modeling 100%
  • Drug Development 28%
  • Normal Human 14%
  70 Citations (SciVal)

  474 Downloads (Pure)

• Factors Affecting Successful Extrapolation of Ibuprofen Exposure from Adults to Pediatric Populations After Oral Administration of a Pediatric Aqueous Suspension

  Statelova, M., Holm, R., Fotaki, N., Reppas, C. & Vertzoni, M., 12 Nov 2020, In: AAPS Journal. 22, 6, 146.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Ibuprofen 100%
  • Pharmacokinetics 28%
  • Paracetamol 14%
  9 Citations (SciVal)

  122 Downloads (Pure)

• Gastrointestinal diseases and their impact on drug solubility: Celiac disease

  Effinger, A., O'Driscoll, C. M., McAllister, M. & Fotaki, N., 1 Sept 2020, In: European Journal of Pharmaceutical Sciences. 152, 105460.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Drug Solubility 100%
  • Gastrointestinal Disease 100%
  • Coeliac Disease 100%
  • Normal Human 16%
  • Bile Salt 16%
  3 Citations (SciVal)

  88 Downloads (Pure)

• Gastrointestinal diseases and their impact on drug solubility: Crohn's disease

  Effinger, A., O'Driscoll, C. M., McAllister, M. & Fotaki, N., 1 Sept 2020, In: European Journal of Pharmaceutical Sciences. 152, 105459.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Drug Solubility 100%
  • Gastrointestinal Disease 100%
  • Crohn's Disease 100%
  • Drug Solubilisation 25%
  • Normal Human 16%
  13 Citations (SciVal)

  99 Downloads (Pure)

• Gastrointestinal diseases and their impact on drug solubility: Ulcerative Colitis

  Effinger, A., M O'Driscoll, C., McAllister, M. & Fotaki, N., 1 Sept 2020, In: European Journal of Pharmaceutical Sciences. 152, 105458.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Drug Solubility 100%
  • Ulcerative Colitis 100%
  • Gastrointestinal Disease 100%
  • Normal Human 30%
  • Lipophilicity 15%
  6 Citations (SciVal)

  88 Downloads (Pure)

• Impact of Food and Drink Administration Vehicles on Paediatric Formulation Performance: Part 1—Effects on Solubility of Poorly Soluble Drugs

  Martir, J., Flanagan, T., Mann, J. & Fotaki, N., 26 Jun 2020, In: AAPS PharmSciTech. 21, 5, 177.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Drug Solubility 100%
  • Bioavailability 100%
  • Aminosalicylic Acid 66%
  • Montelukast 66%
  • Palatability 50%
  15 Citations (SciVal)

• Impact of Food and Drink Administration Vehicles on Paediatric Formulation Performance Part 2: Dissolution of Montelukast Sodium and Mesalazine Formulations

  Martir, J., Flanagan, T., Mann, J. & Fotaki, N., 15 Oct 2020, In: AAPS PharmSciTech. 21, 7, 287.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Aminosalicylic Acid 100%
  • Montelukast 100%
  • Bioavailability 50%
  • Drug Formulation 50%
  • Drug Solubility 50%
  10 Citations (SciVal)