Projects per year
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Research interests
Prof Nikoletta Fotaki is a Greek Pharmacist. She graduated from the National and Kapodistrian University of Athens in Greece and she obtained a MSc in Toxicology from the University of Surrey in the UK. She completed her PhD in Biopharmaceutics-Pharmacokinetics at the School of Pharmacy of the National and Kapodistrian University of Athens in Greece. During this period she worked on various research projects. She worked as a Pharmacist in the National Organisation of Drugs in Greece (EOF) and she was a Postdoctoral Fellow in the School of Pharmacy (National and Kapodistrian University of Athens, Greece) upon completion of her Ph.D degree. After that she was offered a further postdoctoral fellowship by Roche ( New Jersey, USA).
Prof Fotaki’s research and activities are focused on the prediction of oral drug absorption, which is an area of very keen interest in the pharmaceutical world due to the increasing use of libraries to screen structures for potential activity and the need to select leads based not only on potential receptor interactions but also on the basis of ability to be absorbed orally. She is working on the development of in vitro screening tools and associated softwares for predicting oral absorption, the assessment of the impact of changes in drug substance properties and changes in the formulation process on bioavailability , animal models for predicting absorption, and in vitro-in vivo correlations/ in vitro-in vivo relations.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Use of medicines and predictions of pharmacokinetic changes after bariatric surgery
20/09/21 → 19/04/24
Project: UK charity
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P2D Secondment - Biopharmaceutic Strategies and Tools during Drug Development
1/11/15 → 31/08/16
Project: Research council
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Evaluation of In Vitro Tests to Reduce Animal Testing in Drug Toxicology Studies
1/01/15 → 31/12/15
Project: Central government, health and local authorities
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Biopharmaceutics Tools for Rational Formulation Design
Zarmpi, P., McAllister, M., Butler, J. & Fotaki, N., 2022, Biopharmaceutics: From Fundamentals to Industrial Practice. Batchelor, H. (ed.). John Wiley & Sons, LtdResearch output: Chapter or section in a book/report/conference proceeding › Chapter or section
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Oral administration of buparvaquone nanostructured lipid carrier enables in vivo activity against Leishmania infantum
Monteiro, L. M., Löbenberg, R., Barbosa, E. J., de Araujo, G. L. B., Sato, P. K., Kanashiro, E., de Araujo Eliodoro, R. H., Rocha, M., de Freitas, V. L. T., Fotaki, N. & Bou-Chacra, N. A., 1 Feb 2022, In: European Journal of Pharmaceutical Sciences . 169, p. 106097 1 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Performance Evaluation of Montelukast Pediatric Formulations: Part II — a PBPK Modelling Approach
Guimarães, M., Vertzoni, M. & Fotaki, N., 10 Jan 2022, In: AAPS Journal. 24, 1, 27.Research output: Contribution to journal › Article › peer-review
Open Access -
Performance Evaluation of Montelukast Pediatric Formulations: Part I—Age-Related In Vitro Conditions
Guimarães, M., Somville, P., Vertzoni, M. & Fotaki, N., 10 Jan 2022, In: AAPS Journal. 24, 1, 26.Research output: Contribution to journal › Article › peer-review
Open Access -
Understanding the impact of age-related changes in pediatric GI solubility by multivariate data analysis
Guimarães, M., Maharaj, A., Edginton, A., Vertzoni, M. & Fotaki, N., 4 Feb 2022, In: Pharmaceutics. 14, 2, 356.Research output: Contribution to journal › Article › peer-review
Open Access