Projects per year
Personal profile
Research interests
Dr Nikoletta Fotaki is a UK-registered Greek Pharmacist. She graduated from the National and Kapodistrian University of Athens in Greece and she obtained a MSc in Toxicology from the University of Surrey in the UK. She completed her PhD in Biopharmaceutics-Pharmacokinetics at the School of Pharmacy of the National and Kapodistrian University of Athens in Greece. During this period she worked on various research projects. She worked as a Pharmacist in the National Organisation of Drugs in Greece (EOF) and she was a Postdoctoral Fellow in the School of Pharmacy (National and Kapodistrian University of Athens, Greece) upon completion of her Ph.D degree. After that she was offered a further postdoctoral fellowship by Roche ( New Jersey, USA).
Dr Fotaki’s research and activities are focused on the prediction of oral drug absorption, which is an area of very keen interest in the pharmaceutical world due to the increasing use of libraries to screen structures for potential activity and the need to select leads based not only on potential receptor interactions but also on the basis of ability to be absorbed orally. She is working on the development of in vitro screening tools and associated softwares for predicting oral absorption, the assessment of the impact of changes in drug substance properties and changes in the formulation process on bioavailability , animal models for predicting absorption, and in vitro-in vivo correlations/ in vitro-in vivo relations.
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Projects
FAPESP - Bath Scheme 2018
Fotaki, N. & Bou-Chacra, N. A.
1/03/19 → 1/03/20
Project: Research-related funding
P2D Secondment - Biopharmaceutic Strategies and Tools during Drug Development
1/11/15 → 31/08/16
Project: Research council
Evaluation of In Vitro Tests to Reduce Animal Testing in Drug Toxicology Studies
1/01/15 → 31/12/15
Project: Central government, health and local authorities
Research Output
American association of pharmaceutical scientists (AAPS) and Chinese national institutes for food and drug control (NIFDC) joint workshop on dissolution, bioequivalence, product performance, and quality
Lu, X., Ning, B., Fotaki, N., Sharp, S. S., Burgess, D. & Haddouchi, S., 1 Jan 2020, In : Dissolution Technologies. 27, 2, p. 42-50 9 p.Research output: Contribution to journal › Book/Film/Article review
Open Access
A new medium-throughput screening design approach for the development of hydroxymethylnitrofurazone (NFOH) nanostructured lipid carrier for treating leishmaniasis
de Souza, A., Yukuyama, M. N., Barbosa, E. J., Monteiro, L. M., Faloppa, A. C. B., Calixto, L. A., de Barros Araújo, G. L., Fotaki, N., Löbenberg, R. & Bou-Chacra, N. A., 1 May 2020, In : Colloids and Surfaces B: Biointerfaces. 193, 111097.Research output: Contribution to journal › Article
Biopharmaceutical implications of excipient variability on drug dissolution from immediate release products
Zarmpi, P., Flanagan, T., Meehan, E., Mann, J., Østergaard, J. & Fotaki, N., 16 Jul 2020, In : European Journal of Pharmaceutics and Biopharmaceutics. 154, p. 195-209 15 p.Research output: Contribution to journal › Article
Biopharmaceutical understanding of excipient variability on drug apparent solubility based on drug physicochemical properties. Case study: Hypromellose (HPMC)
Zarmpi, P., Flanagan, T., Meehan, E., Mann, J. & Fotaki, N., 2020, In : AAPS Journal. 22, 49.Research output: Contribution to journal › Article
Open Access
2
Citations
(Scopus)
Biopharmaceutical understanding of excipient variability on drug apparent solubility based on drug physicochemical properties. Case study: Superdisintegrants
Zarmpi, P., Flanagan, T., Meehan, E., Mann, J. & Fotaki, N., 31 Mar 2020, In : AAPS Journal. 22, 2, 46.Research output: Contribution to journal › Article
Open Access