Projects per year
Personal profile
Research interests
Prof Nikoletta Fotaki is a Greek Pharmacist. She graduated from the National and Kapodistrian University of Athens in Greece and she obtained a MSc in Toxicology from the University of Surrey in the UK. She completed her PhD in Biopharmaceutics-Pharmacokinetics at the School of Pharmacy of the National and Kapodistrian University of Athens in Greece. During this period she worked on various research projects. She worked as a Pharmacist in the National Organisation of Drugs in Greece (EOF) and she was a Postdoctoral Fellow in the School of Pharmacy (National and Kapodistrian University of Athens, Greece) upon completion of her Ph.D degree. After that she was offered a further postdoctoral fellowship by Roche ( New Jersey, USA).
Prof Fotaki’s research and activities are focused on the prediction of oral drug absorption, which is an area of very keen interest in the pharmaceutical world due to the increasing use of libraries to screen structures for potential activity and the need to select leads based not only on potential receptor interactions but also on the basis of ability to be absorbed orally. She is working on the development of in vitro screening tools and associated softwares for predicting oral absorption, the assessment of the impact of changes in drug substance properties and changes in the formulation process on bioavailability , animal models for predicting absorption, and in vitro-in vivo correlations/ in vitro-in vivo relations.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
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Increasing capacity in the NHS - Development of technologies to increase delivery of injectible medicines in the community
Watts, A. (PI), Fincham Haines, T. (CoI), Fotaki, N. (CoI), Martinez Hernandez, U. (CoI), Tosh, D. (CoI) & Şimşek, Ö. (CoI)
Engineering and Physical Sciences Research Council
1/01/24 → 31/12/28
Project: Research council
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Use of medicines and predictions of pharmacokinetic changes after bariatric surgery
Jones, M. (PI) & Fotaki, N. (CoI)
20/09/21 → 30/06/25
Project: UK charity
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P2D Secondment - Biopharmaceutic Strategies and Tools during Drug Development
Fotaki, N. (PI)
1/11/15 → 31/08/16
Project: Research council
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Assessing the Anticholinergic Cognitive Burden Classification of Putative Anticholinergic Drugs Using Drug Properties
Nishtala, P., Fotaki, N. & Phutietsile, G., 30 Sept 2024, In: British Journal Of Clinical Pharmacology. 90, 9, p. 2236-2255 20 p.Research output: Contribution to journal › Article › peer-review
Open Access -
In Vitro Product Performance Testing of Oral Drug Products: View of the USP Expert Panel
Fotaki, N., D’arcy, D., Demuth, J., Hermans, A., Lu, X., Nir, I., Scheubel, E., Skwierczynski, R. & Hernandez-Cardoso, A., 31 Aug 2024, In: Dissolution Technologies. 31, 3, p. 110-121 12 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Parameterization of Physiologically Based Biopharmaceutics Models: Workshop Summary Report
Pepin, X., Arora, S., Borges, L., Cano-Vega, M., Carducci, T., Chatterjee, P., Chen, G., Cristofoletti, R., Dallmann, A., Delvadia, P., Dressman, J., Fotaki, N., Gray, E., Heimbach, T., Holte, Ø., Kijima, S., Kotzagiorgis, E., Lennernäs, H., Lindahl, A. & Loebenberg, R. & 20 others, , 5 Aug 2024, In: Molecular Pharmaceutics. 21, 8, p. 3697-3731 35 p.Research output: Contribution to journal › Review article › peer-review
Open Access -
Thermal stabilisation of lysozyme through ensilication
Abdulkareem, R., Doekhie, A., Fotaki, N., Koumanov, F., Dodson, C. & Sartbaeva, A., 30 Sept 2024, In: Molecules. 29, 17, 4207.Research output: Contribution to journal › Article › peer-review
Open Access -
A review of paediatric injectable drug delivery to inform the study of product acceptability – An introduction
Ruiz, F., Nunn, A., Gill, A., Clapham, D., Fotaki, N., Salunke, S., Cram, A. & O'Brien, F., 1 Jul 2023, In: European Journal of Pharmaceutics and Biopharmaceutics. 188, p. 265-270 6 p.Research output: Contribution to journal › Review article › peer-review
Open Access2 Citations (SciVal)
Datasets
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Numerical data and higher resolution images for Abdulkareem et al (2024), "Thermal stabilisation of lysozyme through ensilication", Molecules
Abdulkareem, R. (Creator), Fotaki, N. (Creator), Koumanov, F. (Creator), Dodson, C. (Creator) & Sartbaeva, A. (Creator), Zenodo, 2 Sept 2024
Dataset