If you made any changes in Pure these will be visible here soon.

Personal profile

Research interests

Dr Nikoletta Fotaki is a UK-registered Greek Pharmacist. She graduated from the National and Kapodistrian University of Athens in Greece and she obtained a MSc in Toxicology from the University of Surrey in the UK. She completed her PhD in Biopharmaceutics-Pharmacokinetics at the School of Pharmacy of the National and Kapodistrian University of Athens in Greece. During this period she worked on various research projects. She worked as a Pharmacist in the National Organisation of Drugs in Greece (EOF) and she was a Postdoctoral Fellow in the School of Pharmacy (National and Kapodistrian University of Athens, Greece) upon completion of her Ph.D degree. After that she was offered a further postdoctoral fellowship by Roche ( New Jersey, USA).

Dr Fotaki’s research and activities are focused on the prediction of oral drug absorption, which is an area of very keen interest in the pharmaceutical world due to the increasing use of libraries to screen structures for potential activity and the need to select leads based not only on potential receptor interactions but also on the basis of ability to be absorbed orally. She is working on the development of in vitro screening tools and associated softwares for predicting oral absorption, the assessment of the impact of changes in drug substance properties and changes in the formulation process on bioavailability , animal models for predicting absorption, and in vitro-in vivo correlations/ in vitro-in vivo relations.

Fingerprint Dive into the research topics where Nikoletta Fotaki is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 7 Similar Profiles
Pharmaceutical Preparations Medicine & Life Sciences
Stomach Medicine & Life Sciences
Oral Administration Medicine & Life Sciences
Hydrodynamics Medicine & Life Sciences
Solubility Medicine & Life Sciences
Excipients Medicine & Life Sciences
Capsules Medicine & Life Sciences
Nifedipine Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2014 2020

Evaluation of In Vitro Tests to Reduce Animal Testing in Drug Toxicology Studies

Fotaki, N.

Innovate UK

1/01/1531/12/15

Project: Central government, health and local authorities

FAPESP Bath Scheme

Fotaki, N.

1/09/141/08/16

Project: Research-related funding

Accelerating paediatric Formulation Development Through Smart Design and Predictive Science

Fotaki, N.

Innovate UK

1/07/1431/03/18

Project: Central government, health and local authorities

Research Output 2000 2019

Application of the relationship between pharmacokinetics and pharmacodynamics in drug development and therapeutic equivalence: a PEARRL review

Loisios-Konstantinidis, I., Paraiso, R. L. M., Fotaki, N., McAllister, M., Cristofoletti, R. & Dressman, J., 1 Apr 2019, In : Journal of Pharmacy and Pharmacology. 71, 4, p. 699-723 25 p.

Research output: Contribution to journalReview article

Biorelevant release testing of biodegradable microspheres intended for intra-articular administration

Magri, G., Selmin, F., Cilurzo, F. & Fotaki, N., 1 Jun 2019, In : European Journal of Pharmaceutics and Biopharmaceutics. 139, p. 115-122 8 p.

Research output: Contribution to journalArticle

Co-delivery of buparvaquone and polymyxin B in a nanostructured lipid carrier for leishmaniasis treatment

Monteiro, L. M., Löbenberg, R., Fotaki, N., Barros de Araujo, G. L., Cotrim, P. C. & Bou-Chacra, N. A., 1 Sep 2019, In : Journal of Global Antimicrobial Resistance. 18, p. 279-283 5 p.

Research output: Contribution to journalArticle

6 Downloads (Pure)

Effects of medicines used to treat gastrointestinal diseases on the pharmacokinetics of coadministered drugs: A PEARRL Review

Litou, C., Effinger, A., Kostewicz, E. S., Box, K. J., Fotaki, N. & Dressman, J. B., 1 Apr 2019, In : Pharmacy and Pharmacology Communications. 71, 4, p. 643-673 31 p.

Research output: Contribution to journalReview article

Open Access
File
Gastrointestinal Diseases
Pharmacokinetics
Pharmaceutical Preparations
Microbiota
Treatment Failure

Thesis

Biopharmaceutical considerations and in vitro-in vivo correlations (IVIVCs) for orally administered amorphous formulations

Author: Long, C. M., 10 Jun 2014

Supervisor: Fotaki, N. (Supervisor)

Student thesis: Doctoral ThesisPhD

File

Biopharmaceutical understanding of excipient variability in drug product performance

Author: Zarmpi, P., 4 Sep 2019

Supervisor: Fotaki, N. (Supervisor) & Bolhuis, A. (Supervisor)

Student thesis: Doctoral ThesisPhD

Clinically relevant in vitro dissolution/release testing for parenteral formulations

Author: Diaz De Leon Ortega, R., 3 Apr 2019

Supervisor: Pourzand, C. (Supervisor) & Fotaki, N. (Supervisor)

Student thesis: Doctoral ThesisPhD

Formulation performance in paediatric patients - in vitro predictive models and biowaivers

Author: Martir, J., 4 Sep 2019

Supervisor: Fotaki, N. (Supervisor) & Husbands, S. (Supervisor)

Student thesis: Doctoral ThesisPhD

In vitro and Physiologically Based Pharmacokinetic models for pharmaceutical cocrystals Irena Tomaszewska

Author: Tomaszewska, I., 31 Dec 2013

Supervisor: Fotaki, N. (Supervisor) & Price, R. (Supervisor)

Student thesis: Doctoral ThesisPhD

File