Projects per year
Personal profile
Research interests
Prof Nikoletta Fotaki is a Greek Pharmacist. She graduated from the National and Kapodistrian University of Athens in Greece and she obtained a MSc in Toxicology from the University of Surrey in the UK. She completed her PhD in Biopharmaceutics-Pharmacokinetics at the School of Pharmacy of the National and Kapodistrian University of Athens in Greece. During this period she worked on various research projects. She worked as a Pharmacist in the National Organisation of Drugs in Greece (EOF) and she was a Postdoctoral Fellow in the School of Pharmacy (National and Kapodistrian University of Athens, Greece) upon completion of her Ph.D degree. After that she was offered a further postdoctoral fellowship by Roche ( New Jersey, USA).
Prof Fotaki’s research and activities are focused on the prediction of oral drug absorption, which is an area of very keen interest in the pharmaceutical world due to the increasing use of libraries to screen structures for potential activity and the need to select leads based not only on potential receptor interactions but also on the basis of ability to be absorbed orally. She is working on the development of in vitro screening tools and associated softwares for predicting oral absorption, the assessment of the impact of changes in drug substance properties and changes in the formulation process on bioavailability , animal models for predicting absorption, and in vitro-in vivo correlations/ in vitro-in vivo relations.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
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Increasing capacity in the NHS - Development of technologies to increase delivery of injectible medicines in the community
Watts, A. (PI), Fincham Haines, T. (CoI), Fotaki, N. (CoI), Martinez Hernandez, U. (CoI), Tosh, D. (CoI) & Şimşek, Ö. (CoI)
Engineering and Physical Sciences Research Council
1/01/24 → 31/12/28
Project: Research council
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Use of medicines and predictions of pharmacokinetic changes after bariatric surgery
Jones, M. (PI) & Fotaki, N. (CoI)
20/09/21 → 30/06/25
Project: UK charity
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P2D Secondment - Biopharmaceutic Strategies and Tools during Drug Development
Fotaki, N. (PI)
1/11/15 → 31/08/16
Project: Research council
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Assessing the Anticholinergic Cognitive Burden Classification of Putative Anticholinergic Drugs Using Drug Properties
Nishtala, P., Fotaki, N. & Phutietsile, G., 30 Sept 2024, In: British Journal Of Clinical Pharmacology. 90, 9, p. 2236-2255 20 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Drug–Drug Interaction Between Dihydroartemisinin–Piperaquine and Sulfadoxine-Pyrimethamine During Malaria Chemoprevention in Pregnant Women
Mwebaza, N., Roh, M. E., Geng, Y. Z., Opio, L., Opira, B., Marzan, F., Mwima, M. W., Ssemukuye, T., Guo, K., Gingrich, D., Fotaki, N., Kakuru, A., Kizza, J., Aguti, M., Adrama, H., Kamya, M., Dorsey, G., Rosenthal, P. J., Aweeka, F. T. & Huang, L., 14 Oct 2024, (E-pub ahead of print) In: Clinical Pharmacology and Therapeutics.Research output: Contribution to journal › Article › peer-review
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In Vitro Product Performance Testing of Oral Drug Products: View of the USP Expert Panel
Fotaki, N., D’arcy, D., Demuth, J., Hermans, A., Lu, X., Nir, I., Scheubel, E., Skwierczynski, R. & Hernandez-Cardoso, A., 31 Aug 2024, In: Dissolution Technologies. 31, 3, p. 110-121 12 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Parameterization of Physiologically Based Biopharmaceutics Models: Workshop Summary Report
Pepin, X., Arora, S., Borges, L., Cano-Vega, M., Carducci, T., Chatterjee, P., Chen, G., Cristofoletti, R., Dallmann, A., Delvadia, P., Dressman, J., Fotaki, N., Gray, E., Heimbach, T., Holte, Ø., Kijima, S., Kotzagiorgis, E., Lennernäs, H., Lindahl, A. & Loebenberg, R. & 20 others, , 5 Aug 2024, In: Molecular Pharmaceutics. 21, 8, p. 3697-3731 35 p.Research output: Contribution to journal › Review article › peer-review
Open Access5 Citations (SciVal) -
Thermal stabilisation of lysozyme through ensilication
Abdulkareem, R., Doekhie, A., Fotaki, N., Koumanov, F., Dodson, C. & Sartbaeva, A., 30 Sept 2024, In: Molecules. 29, 17, 4207.Research output: Contribution to journal › Article › peer-review
Open Access
Datasets
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Numerical data and higher resolution images for Abdulkareem et al (2024), "Thermal stabilisation of lysozyme through ensilication", Molecules
Abdulkareem, R. (Creator), Fotaki, N. (Creator), Koumanov, F. (Creator), Dodson, C. (Creator) & Sartbaeva, A. (Creator), Zenodo, 2 Sept 2024
Dataset
Activities
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“Trends in Utility of Animal Studies in Oral Drug Development” Hot topic, AAPS PharmSci 360
Fotaki, N. (Speaker)
23 Oct 2024Activity: Academic conferences and events (excluding conference publications) › Conference presentation / attendance
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“Biopharmaceutics Modeling in support of drug product development” 21st IPTS - International Pharmaceutical Technology Symposium 2024
Fotaki, N. (Speaker)
9 Sept 2024Activity: Academic conferences and events (excluding conference publications) › Conference presentation / attendance
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“Experiences of dissolution, IVIVC and regulatory applications from other dosage forms” EPAG workshop on Dissolution testing of inhaled products
Fotaki, N. (Speaker)
15 Oct 2024Activity: Academic conferences and events (excluding conference publications) › Conference presentation / attendance
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External examiner for PhD; Aristotle university of Thessaloniki, Greece
Fotaki, N. (Examiner)
1 Nov 2024Activity: External examination and supervision › External examination
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External examiner for PhD; University of Nottingham, UK
Fotaki, N. (Examiner)
22 Nov 2024Activity: External examination and supervision › External examination