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Tumour Necrosis Factor Inhibitor monotherapy versus combination therapy for the treatment of psoriatic arthritis: combined analysis of European biologics databases

Thomas, M., Shaddick, G., Charlton, R., Cavill, C., Holland, R., Iannone, F., Lapadula, G., Lopriore, S., Zavada, J., Uher, M., Pavelka, K., Szczukova, L., Sidiropolous, P., Flouri, I., Drosos, A., Möller, B., Nissen, M., Müller, R., Scherer, A., McHugh, N. & 1 others, Nightingale, A., 5 Mar 2020, (Accepted/In press) In : The Journal of Rheumatology.

Research output: Contribution to journalArticle

2019

Comparison of Three Immunoassays for the Detection of Myositis Specific Antibodies

Mahler, M., Betteridge, Z., Bentow, C., Richards, M., Seaman, A., Chinoy, H. & McHugh, N., 30 Apr 2019, In : Frontiers in Immunology. 10, p. 1-5 5 p., 848.

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Open Access
5 Citations (Scopus)

Diagnosis and initial management in psoriatic arthritis: a qualitative study with patients

Dures, E., Bowen, C., Brooke, M., Lord, J., Tillett, W., McHugh, N. & Hewlett, S., 26 Aug 2019, In : Rheumatology Advances in Practice. 3, 2, rkz022.

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Open Access
1 Citation (Scopus)
Open Access

Evaluation of the Economic Burden of Psoriatic Arthritis and the Relationship Between Functional Status and Healthcare Costs

McHugh, N., Maguire, Á., Handel, I., Tillett, W., Morris, J., Hawkins, N., Cavill, C., Korendowych, E. & Mughal, F., 31 Aug 2019, In : The Journal of Rheumatology. 46, 8, 190083.

Research output: Contribution to journalArticle

Expression of Myxovirus-resistance Protein A: A Possible Marker of Muscle Disease Activity and Autoantibody Specificities in Juvenile Dermatomyositis

Soponkanaporn, S., Deakin, C. T., Schutz, P. W., Marshall, L. R., Yasin, S. A., Johnson, C. M., Sag, E., Tansley, S. L., McHugh, N. J., Wedderburn, L. R. & Jacques, T. S., 1 Jun 2019, In : Neuropathology and Applied Neurobiology. 45, 4, p. 410-420 11 p.

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Open Access
2 Citations (Scopus)
12 Downloads (Pure)

Fatigue in primary Sjögren’s syndrome (pSS) is associated with lower levels of proinflammatory cytokines: a validation study

UK Primary Sjögren’s Syndrome registry, 1 Nov 2019, In : Rheumatology International. 39, 11, p. 1867-1873 7 p.

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Open Access
3 Citations (Scopus)

Focused HLA analysis in Caucasians with myositis identifies significant associations with autoantibody subgroups

Myositis Genetics Consortium (MYOGEN), 1 Jul 2019, In : Annals of the Rheumatic Diseases. 78, 7, p. 996-1002 7 p.

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Open Access
5 Citations (Scopus)

Frequency, mutual exclusivity and clinical associations of myositis autoantibodies in a combined European cohort of idiopathic inflammatory myopathy patients

Betteridge, Z., Tansley, S., Shaddick, G., Chinoy, H., Cooper, R. G., New, R. P., Lilleker, J. B., Vencovsky, J., Chazarain, L., Danko, K., Nagy-Vincze, M., Bodoki, L., Dastmalchi, M., Ekholm, L., Lundberg, I. E. & McHugh, N., 1 Jul 2019, In : Journal of Autoimmunity. 101, p. 48-55 8 p.

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Open Access
9 Citations (Scopus)

Genome-wide association study of eosinophilic granulomatosis with polyangiitis reveals genomic loci stratified by ANCA status

The European Vasculitis Genetics Consortium, 1 Dec 2019, In : Nature Communications. 10, 1, 5120.

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Open Access
4 Citations (Scopus)

Histological heterogeneity in a large clinical cohort of juvenile idiopathic inflammatory myopathy: analysis by myositis autoantibody and pathological features

UK Juvenile Dermatomyositis Research Group (UK-Ireland), 1 Aug 2019, In : Neuropathology and Applied Neurobiology. 45, 5, p. 495-512 18 p.

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Open Access
4 Citations (Scopus)

Identification of a novel autoantigen eukaryotic initiation factor 3 associated with polymyositis

Betteridge, Z., Chinoy, H., Vencovsky, J., Winer, J., Putchakayala, K., Ho, P., Lundberg, I., Danko, K., Cooper, R. & McHugh, N., 19 Aug 2019, (Accepted/In press) In : Rheumatology (Oxford, England).

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Modifiable risk factors and the development of psoriatic arthritis in people with psoriasis

PROMPT Study Group, 18 Jun 2019, In : British Journal of Dermatology. p. 1-7 7 p.

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1 Citation (Scopus)

Pain and depression are associated with both physical and mental fatigue independently of comorbidities and medications in primary Sjögren's syndrome

Hackett, K. L., Davies, K., Tarn, J., Bragg, R., Hargreaves, B., Miyamoto, S., McMeekin, P., Mitchell, S., Bowman, S., Price, E. J., Pease, C., Emery, P., Andrews, J., Lanyon, P., Hunter, J., Gupta, M., Bombardieri, M., Sutcliffe, N., Pitzalis, C., McLaren, J. & 15 others, Cooper, A., Regan, M., Giles, I., Isenberg, D., Vadivelu, S., Coady, D., Dasgupta, B., McHugh, N., Young-Min, S., Moots, R., Gendi, N., Akil, M., Griffiths, B., Lendrem, D. W. & Ng, W. F., 24 Apr 2019, In : RMD Open. 5, 1, p. 1-7 7 p., e000885.

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Open Access

Predictors, demographics and frequency of sustained remission and low disease activity in anti-tumour necrosis factor-treated rheumatoid arthritis patients

BSRBR-RA Contributors Group , 1 Dec 2019, In : Rheumatology. 58, 12, p. 2162-2169 8 p., kez188.

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Open Access
3 Citations (Scopus)

PsAID12 Provisionally Endorsed at OMERACT 2018 as Core Outcome Measure to Assess Psoriatic Arthritis-specific Health-related Quality of Life in Clinical Trials

Orbai, A-M., Holland, R., Leung, Y. Y., Tillett, W., Goel, N., Christensen, R., McHugh, N., Gossec, L., de Wit, M., Højgaard, P., Coates, L. C., Mease, P. J., Birt, J., Fallon, L., FitzGerald, O., Ogdie, A., Shea, B., Strand, V., Callis Duffin, K., Tugwell, P. & 2 others, Beaton, D. & Gladman, D. D., 1 Aug 2019, In : The Journal of Rheumatology. 46, 1, p. 990-995 6 p.

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1 Citation (Scopus)
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Psoriatic nail dystrophy is associated with erosive disease in the distal interphalangeal joints in psoriatic arthritis: a retrospective cohort study

Antony, A., Allard, A., Rambojun, A., Lovell, C. R., Shaddick, G., Robinson, G., Jadon, D. R., Holland, R., Cavill, C., Korendowych, E., McHugh, N. J. & Tillett, W., 1 Sep 2019, In : The Journal of Rheumatology. 46, 9, p. 1097-1102 6 p.

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Open Access
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Risk of type 2 diabetes and cardiovascular disease in an incident cohort of people with psoriatic arthritis: a population-based cohort study

PROMPT Study Group, 1 Jan 2019, In : Rheumatology. 58, 1, p. 144-148 5 p.

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3 Citations (Scopus)
21 Downloads (Pure)

Symptom-based stratification of patients with primary Sjögren's syndrome: multi-dimensional characterisation of international observational cohorts and reanalyses of randomised clinical trials

UK Primary Sjögren's Syndrome Registry, Leeds CTRU & French ASSESS cohort, 1 Oct 2019, In : The Lancet Rheumatology. 1, 2, p. e85-e94 10 p.

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Open Access
3 Citations (Scopus)

The myositis clinical phenotype associated with anti-Zo autoantibodies: a case series of nine UK patients

Tansley, S. L., Betteridge, Z., Lu, H., Davies, E., Rothwell, S., New, P. P., Chinoy, H., Gordon, P., Gunawardena, H., Lloyd, M., Stratton, R., Cooper, R. & McHugh, N. J., 26 Oct 2019, In : Rheumatology. kez504.

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Open Access

The performance of the European League Against Rheumatism/American College of Rheumatology idiopathic inflammatory myopathies classification criteria in an expert-defined 10 year incident cohort

Parker, M. J. S., Oldroyd, A., Roberts, M. E., Lilleker, J. B., Betteridge, Z. E., McHugh, N. J., Herrick, A. L., Cooper, R. G. & Chinoy, H., 1 Mar 2019, In : Rheumatology. 58, 3, p. 468-475 8 p.

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Open Access
2 Citations (Scopus)

Trajectory of radiographic change over a decade: the effect of transition from conventional synthetic disease-modifying antirheumatic drugs to anti-tumour necrosis factor in patients with psoriatic arthritis

Allard, A., Antony, A., Shaddick, G., Jadon, D. R., Cavill, C., Robinson, G., Korendowych, E., McHugh, N. & Tillett, W., 1 Feb 2019, In : Rheumatology. 58, 2, p. 269-273 5 p.

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2 Citations (Scopus)
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2018

Advancing research paradigms and pathophysiological pathways in psoriatic arthritis and ankylosing spondylitis: Proceedings of the 2017 Platform for the Exchange of Expertise and Research (PEER) meeting

Abraham, S., Barton, A., Eder, L., Lim, A., McGonagle, D., McHugh, N., Pennington, S., Sengupta, R., Siebert, S., Bowness, P., Schafer, P. H., Cullen, E. & FitzGerald, O., 15 Oct 2018, In : Seminars in Arthritis and Rheumatism. 48, p. 1005-1013 9 p.

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Open Access

A Multicenter Study of the Validity and Reliability of Responses to Hand Cold Challenge as Measured by Laser Speckle Contrast Imaging and Thermography: outcome measures for systemic sclerosis-related Raynaud's phenomenon

Wilkinson, J. D., Leggett, S. A., Marjanovic, E. J., Moore, T. L., Allen, J., Anderson, M. E., Britton, J., Buch, M. H., Galdo, F. D., Denton, C. P., Dinsdale, G., Griffiths, B., Hall, F., Howell, K., MacDonald, A., McHugh, N. J., Manning, J. B., Pauling, J. D., Roberts, C., Shipley, J. A. & 2 others, Herrick, A. L. & Murray, A. K., 1 Jun 2018, In : Arthritis & Rheumatology. 70, 6, p. 903-911 9 p.

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23 Citations (Scopus)
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A multi-national qualitative research study exploring the patient experience of Raynaud's phenomenon in systemic sclerosis

Pauling, J. D., Domsic, R. T., Saketkoo, L. A., Almeida, C., Withey, J., Jay, H., Frech, T. M., Ingegnoli, F., Dures, E., Robson, J., McHugh, N. J., Herrick, A. L., Matucci-Cerinic, M., Khanna, D. & Hewlett, S., 30 Sep 2018, In : Arthritis Care and Research. 70, 9, p. 1373-1384

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Open Access
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16 Citations (Scopus)
49 Downloads (Pure)

B-cell activity markers are associated with different disease activity domains in primary Sjögren's syndrome

for the UK Primary Sjögren's Syndrome Registry, 1 Jul 2018, In : Rheumatology (United Kingdom). 57, 7, p. 1222-1227 6 p.

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Open Access
5 Citations (Scopus)

Comparison of ESSDAI and ClinESSDAI in potential optimisation of trial outcomes in primary Sjögren's syndrome: examination of data from the UK Primary Sjögren's Syndrome Registry

Dumusc, A., Ng, W-F., James, K., Griffiths, B., Price, E., Pease, C., Emery, P., Lanyon, P., Jones, A., Bombardieri, M., Sutcliffe, N., Pitzalis, C., Gupta, M., McLaren, J., Cooper, A., Giles, I., Isenberg, D., Saravanan, V., Coady, D., Dasgupta, B. & 10 others, McHugh, N., Young-Min, S., Moots, R., Gendi, N., Akil, M., Barone, F., Fisher, B., Rauz, S., Richards, A. & Bowman, S., 7 Feb 2018, In : Swiss Medical Weekly. 148, 5-6, p. w14588 14588.

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Open Access
3 Citations (Scopus)

Exploring the illness representations of people with psoriatic arthritis: A secondary analysis of focus group data

On behalf of the PROMPT Study Group, 1 Jul 2018, In : Rheumatology Advances in Practice. 2, 2, p. 1-7 7 p.

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Open Access
1 Citation (Scopus)
Open Access
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Genetic background may contribute to the latitude-dependent prevalence of dermatomyositis and anti-TIF1-γ autoantibodies in adult patients with myositis

The Myositis Genetics Consortium (MYOGEN), 8 Jun 2018, In : Arthritis Research and Therapy. 20, 1, p. 117 5 p., 117.

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Open Access
4 Citations (Scopus)

GRAPPA-OMERACT consensus-based recommendations and research agenda for use of composite measures and treatment targets in PsA

Coates, L. C., Fitzgerald, O., Merola, J. F., Smolen, J., van Mens, L. J. J., Bertheussen, H., Boehncke, W-H., Callis Duffin, K., Campbell, W., de Wit, M., Gladman, D. D., Gottlieb, A., James, J., Kavanaugh, A. F., Kristensen, L. E., Kvien, T. K., Luger, T., McHugh, N., Mease, P. J., Nash, P. & 6 others, Ogdie, A., Rosen, C. F., Strand, V., Tillett, W., Veale, D. J. & Helliwell, P. S., 31 Mar 2018, In : Arthritis & Rheumatology. 70, 3, p. 345-355

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Open Access
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24 Citations (Scopus)
26 Downloads (Pure)

Investigation of myositis and scleroderma specific autoantibodies in patients with lung cancer

Betteridge, Z. E., Priest, L., Cooper, R. G., McHugh, N. J., Blackhall, F. & Lamb, J. A., 9 Aug 2018, In : Arthritis Research & Therapy. 20, 1, 176.

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Open Access
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Long-term effectiveness of tumour necrosis factor-α inhibitor treatment for psoriatic arthritis in the UK: A multicentre retrospective study

Clunie, G., McInnes, I. B., Barkham, N., Marzo-Ortega, H., Patel, Y., Gough, A., Packham, J., Kyle, S., Kirkham, B., Sheeran, T., Coope, H., Bishop-Bailey, A. & McHugh, N., 2018, In : Rheumatology Advances in Practice. 2, 2, p. 1-11 11 p.

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Open Access
1 Citation (Scopus)

Mixed-Methods Study Identifying Key Intervention Targets to Improve Participation in Daily Living Activities in Primary Sjögren's Syndrome Patients

United Kingdom Primary Sjögren's Syndrome Registry, 1 Jul 2018, In : Arthritis Care and Research. 70, 7, p. 1064-1073 10 p.

Research output: Contribution to journalArticle

Open Access
5 Citations (Scopus)

Patient-reported outcome instruments for assessing Raynaud’s phenomenon in systemic sclerosis: A SCTC vascular working group report

Pauling, J. D., Frech, T. M., Hughes, M., Gordon, J. K., Domsic, R. T., Anderson, M. E., Ingegnoli, F., McHugh, N. J., Johnson, S. R., Hudson, M., Boin, F., Ong, V. H., Matucci-Cerinic, M., Altorok, N., Scolnik, M., Nikpour, M., Shah, A., Pope, J. E., Khanna, D. & Herrick, A. L., 1 Oct 2018, In : Journal of Scleroderma and Related Disorders. 3, 3, p. 249-252 4 p.

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Open Access
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9 Citations (Scopus)
29 Downloads (Pure)

Patterns and predictors of skin score change in early diffuse systemic sclerosis from the European Scleroderma Observational Study

Herrick, A. L., Peytrignet, S., Lunt, M., Pan, X., Hesselstrand, R., Mouthon, L., Silman, A. J., Dinsdale, G., Brown, E., Czirják, L., Distler, J. H. W., Distler, O., Fligelstone, K., Gregory, W. J., Ochiel, R., Vonk, M. C., Ancuţa, C., Ong, V. H., Farge, D., Hudson, M. & 45 others, Matucci-Cerinic, M., Balbir-Gurman, A., Midtvedt, Ø., Jobanputra, P., Jordan, A. C., Stevens, W., Moinzadeh, P., Hall, F. C., Agard, C., Anderson, M. E., Diot, E., Madhok, R., Akil, M., Buch, M. H., Chung, L., Damjanov, N. S., Gunawardena, H., Lanyon, P., Ahmad, Y., Chakravarty, K., Jacobsen, S., MacGregor, A. J., McHugh, N., Müller-Ladner, U., Riemekasten, G., Becker, M., Roddy, J., Carreira, P. E., Fauchais, A. L., Hachulla, E., Hamilton, J., İnanç, M., McLaren, J. S., van Laar, J. M., Pathare, S., Proudman, S. M., Rudin, A., Sahhar, J., Coppere, B., Serratrice, C., Sheeran, T., Veale, D. J., Grange, C., Trad, G-S. & Denton, C. P., 1 Apr 2018, In : Annals of the Rheumatic Diseases. 77, 4, p. 563-570 8 p.

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Open Access
11 Citations (Scopus)
Open Access
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9 Citations (Scopus)
47 Downloads (Pure)

Short-term efficacy and safety of rituximab therapy in refractory systemic lupus erythematosus: results from the British Isles Lupus Assessment Group Biologics Register

McCarthy, E. M., Sutton, E., Nesbit, S., White, J., Parker, B., Jayne, D., Griffiths, B., Isenberg, D. A., Rahman, A., Gordon, C., D'Cruz, D. P., Rhodes, B., Lanyon, P., Vital, E. M., Yee, C-S., Edwards, C. J., Teh, L-S., Akil, M., McHugh, N. J., Zoma, A. & 1 others, Bruce, I. N., 1 Mar 2018, In : Rheumatology. 57, 3, p. 470-479 10 p.

Research output: Contribution to journalArticle

Open Access
9 Citations (Scopus)
8 Citations (Scopus)

Validation of the Psoriatic Arthritis Impact of Disease (PsAID) Questionnaire and its potential as a single-item outcome measure in clinical practice

Holland, R., Tillett, W., Korendowych, E., Cavill, C., Waldron, N., Brooke, M. & McHugh, N. J., 12 Feb 2018, In : Annals of the Rheumatic Diseases. 77, 3, p. 343-347 5 p.

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Open Access
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10 Citations (Scopus)
36 Downloads (Pure)
2017

A Multicenter Nominal Group Study to Rank Outcomes Important to Patients, and Their Representation in Existing Composite Outcome Measures for Psoriatic Arthritis

Tillett, W., Dures, E., Hewlett, S., Helliwell, P. S., Fitzgerald, O., Brooke, M., James, J., Lord, J., Bowen, C., de Wit, M., Orbai, A-M., McHugh, N. & PROMPT study group, 4 Oct 2017, In : The Journal of Rheumatology. 44, 10, p. 1445-1452

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Open Access
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6 Citations (Scopus)
116 Downloads (Pure)

Anti-HMGCR Autoantibodies in Juvenile Idiopathic Inflammatory Myopathies Identify a Rare but Clinically Important Subset of Patients

Tansley, S. L., Betteridge, Z. E., Simou, S., Jacques, T. S., Pilkington, C., Wood, M., Warrier, K., Wedderburn, L. R. & McHugh, N. J., 1 Apr 2017, In : The Journal of Rheumatology. 44, 4, p. 488-492 5 p.

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Open Access
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22 Citations (Scopus)
249 Downloads (Pure)

A rare coding allele in IFIH1 is protective for psoriatic arthritis

Budu-Aggrey, A., Bowes, J., Stuart, P. E., Zawistowski, M., Tsoi, L. C., Nair, R., Jadon, D. R., McHugh, N., Korendowych, E., Elder, J. T., Barton, A. & Raychaudhuri, S., 1 Jul 2017, In : Annals of the Rheumatic Diseases. 76, 7, p. 1321-1324

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Open Access
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3 Citations (Scopus)
57 Downloads (Pure)

Autoantibodies in juvenile-onset myositis: Their diagnostic value and associated clinical phenotype in a large UK cohort

on behalf of the Juvenile Dermatomyositis Research Group, 1 Nov 2017, In : Journal of Autoimmunity. 84, p. 55-64 10 p.

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Open Access
30 Citations (Scopus)

Axial Disease in Psoriatic Arthritis study: defining the clinical and radiographic phenotype of psoriatic spondyloarthritis

Jadon, D. R., Sengupta, R., Nightingale, A., Lindsay, M., Korendowych, E., Robinson, G., Jobling, A., Shaddick, G., Bi, J., Winchester, R., Giles, J. T. & McHugh, N. J., 10 Mar 2017, In : Annals of the Rheumatic Diseases. 76, 4, p. 701-707 7 p.

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Open Access
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21 Citations (Scopus)
127 Downloads (Pure)

Cross-phenotype association mapping of the MHC identifies genetic variants that differentiate psoriatic arthritis from psoriasis

Bowes, J., Ashcroft, J., Dand, N., Jalali-Najafabadi, F., Bellou, E., Ho, P., Marzo-Ortega, H., Helliwell, P. S., Feletar, M., Ryan, A. W., Kane, D. J., Korendowych, E., Simpson, M. A., Packham, J., McManus, R., Brown, M. A., Smith, C. H., Barker, J. N., McHugh, N., Fitzgerald, O. & 2 others, Warren, R. B. & Barton, A., 1 Oct 2017, In : Annals of the Rheumatic Diseases. 76, p. 1774-1779

Research output: Contribution to journalArticle

Open Access
16 Citations (Scopus)

Cytosolic 5'-nucleotidase 1A autoantibody profile and clinical characteristics in inclusion body myositis

Lilleker, J. B., Rietveld, A., Pye, S. R., Mariampillai, K., Benveniste, O., Peeters, M. T. J., Miller, J. A. L., Hanna, M. G., Machado, P. M., Parton, M. J., Gheorghe, K. R., Badrising, U. A., Lundberg, I. E., Sacconi, S., Herbert, M. K., McHugh, N. J., Lecky, B. R. F., Brierley, C., Hilton-Jones, D., Lamb, J. A. & 7 others, Roberts, M. E., Cooper, R. G., Saris, C. G. J., Pruijn, G. J. M., Chinoy, H., van Engelen, B. G. M. & all UKMYONET contributors, 1 May 2017, In : Annals of the Rheumatic Diseases. 76, 5

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Open Access
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33 Citations (Scopus)
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Disability, fatigue, pain and their associates in early diffuse cutaneous systemic sclerosis: the European Scleroderma Observational Study

Peytrignet, S., Denton, C. P., Lunt, M., Hesselstrand, R., Mouthon, L., Silman, A., Pan, X., Brown, E., Czirják, L., Distler, J. H. W., Distler, O., Fligelstone, K., Gregory, W. J., Ochiel, R., Vonk, M., Ancuta, C., Ong, V. H., Farge, D., Hudson, M., Matucci-Cerinic, M. & 43 others, Balbir-Gurman, A., Midtvedt, Ø., Jordan, A. C., Stevens, W., Moinzadeh, P., Hall, F. C., Agard, C., Anderson, M. E., Diot, E., Madhok, R., Akil, M., Buch, M. H., Chung, L., Damjanov, N., Gunawardena, H., Lanyon, P., Ahmad, Y., Chakravarty, K., Jacobsen, S., MacGregor, A. J., McHugh, N., Müller-Ladner, U., Riemekasten, G., Becker, M., Roddy, J., Carreira, P. E., Fauchais, A. L., Hachulla, E., Hamilton, J., İnanç, M., McLaren, J. S., van Laar, J. M., Pathare, S., Proudman, S., Rudin, A., Sahhar, J., Coppere, B., Serratrice, C., Sheeran, T., Veale, D. J., Grange, C., Trad, G-S. & Herrick, A. L., 30 Nov 2017, In : Rheumatology. 12 p.

Research output: Contribution to journalArticle

Open Access
10 Citations (Scopus)